Transcription factor GATA4 is activated but not required for insulin-like growth factor 1 (IGF1)-induced cardiac hypertrophy

Journal of Biological Chemistry

Volumn 287, Issue 13, 2012, Pages 9827-9834

  Bisping, Egbert ^a,b   Ikeda, Sadakatsu ^c   Sedej, Miriam ^b   Wakula, Paulina ^a   McMullen, Julie R ^d   Tarnavski, Oleg ^e   Sedej, Simon ^a   Izumo, Seigo ^f   Pu, William T ^c   Pieske, Burkert ^a,b  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^f CVM Consulting   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC EFFECT; CARDIAC HYPERTROPHY; CARDIAC STRUCTURE; CELL SURVIVAL; DNA BINDING ACTIVITY; HEART DISEASE; IGF1 RECEPTOR; IN-VITRO; INSULIN-LIKE GROWTH FACTOR; NEONATAL RAT; NUCLEAR ACCUMULATION; OVER-EXPRESSION; PHENYLEPHRINE; RNA INTERFERENCE; TARGET GENES; THERAPEUTIC EFFECTS; VENTRICULAR MYOCYTES;

GENES; HEART; INSULIN; PEPTIDES; PHOSPHORYLATION; RNA; TRANSCRIPTION FACTORS;

PATHOLOGY;

PHENYLEPHRINE; RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR GATA 4;

ALPHA SKELETAL ACTIN GENE; ANIMAL CELL; ARTICLE; ATRIAL NATRIURETIC PEPTIDE GENE; BETA MYOSIN HEAVY CHAIN GENE; BIOACCUMULATION; BRAIN NATRIURETIC PEPTIDE GENE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE SILENCING; GENE TARGETING; HAPLOINSUFFICIENCY; HEART CELL CULTURE; HEART FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MYOSIN LIGHT CHAIN GENE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TROPONIN I GENE;

ANIMALS; CARDIOMEGALY; CELLS, CULTURED; GATA4 TRANSCRIPTION FACTOR; GENE KNOCKDOWN TECHNIQUES; HEART VENTRICLES; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR;

MUS; RATTUS;

EID: 84858990468     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.338749     Document Type: Article

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