Formulation development and evaluation of alginate microspheres of ibuprofen

Journal of Young Pharmacists

Volumn 4, Issue 1, 2012, Pages 13-16

  Nagpal, M ^a   Maheshwari, D ^b   Rakha, P ^b   Dureja, H ^c   Goyal, S ^d   Dhingra, G ^e  

^a CHITKARA UNIVERSITY   (India)

^b Rajendra Institute of Technology and Sciences   (India)

^c MAHARSHI DAYANAND UNIVERSITY   (India)

^d Department of Pharmaceutical Chemistry   (India)

^e NCRD Sterling Institute of Pharmacy   (India)

Author keywords

Factorial design; microsphere; multiple regression; particle size analysis; scanning electron microscopy

Indexed keywords

ALGINIC ACID; CALCIUM CHLORIDE; IBUPROFEN; MAGNESIUM STEARATE; MICROSPHERE;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG FORMULATION; EMULSION; ENCAPSULATION; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; VISCOSITY;

EID: 84858974674     PISSN: 09751483     EISSN: 09751505     Source Type: Journal    
DOI: 10.4103/0975-1483.93573     Document Type: Article

References (11)

1. th EDITION, New York: Lippincott Williams and Wilkins; 2005.
2. Ghosh SK, editors. Functional Coatings and Microencapsulation: A general perspective. 2006, Weinheim: Wiley-VCH GmBH and Co. KGaA; 2006.
3. Sam MT, Gayathri DS, Prasanth V, Vinod B. NSAIDs as microspheres. Int J Pharmacology 2008;6:1
4. Devrim B, Canefe K. Preparation and evaluation of modified release ibuprofen microspheres with acrylic polymers (eudragit) by quasi emulsion solvent diffusion method: Effect of variables. Acta Poloniae Pharm Drug Res 2006;63:521-34. (Pubitemid 351360457)
5. Rastogi R, Sultana Y, Aqil M, Ali A, Kumar S, Chuttani K, Mishra AK. Alginate microspheres of Isoniazoid for oral sustained drug delivery. Int. J Pharm 2007;334:71-7. (Pubitemid 46400315)
6. George M, Abraham TE. Polyionic hydrocolloids for the intestinal delivery of protein drugs alginate and chitosan-a-review. J Controlled Release 2006;114:1-14. (Pubitemid 44131680)
7. Lee BJ, Cui JH, Kim TW, Heo MY, Kim CK. Biphasic release characteristics of dual drug loaded alginate beads. Arch Pharm Res 1998;21:645-50.
8. Chawla V, Tiwari AK, Gupta S. Characterization of polyvinyl alcohol microspheres of diclofenace sodium application of statistical design. Drug Dev Ind Pharm 2000;26:675-80. (Pubitemid 30317074)
9. Rahman Z, Kohli K, Khar RK, Ali M, Charoo NA, Shamsher AA. Characterization of 5-fluorouracil microspheres for colonic delivery. AAPS PharmSciTech 2006;7:E47.
10. Horoz BB, Kliçarslan M, Yüksel N, Baykara T. Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres. AAPS PharmSciTech 2006;7:E16.
11. Thompson CJ, Hansford D, Higgins S, Rostron C, Hutcheon GA, Munday DL. Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters. Int J Pharm 2007;329:53-61. (Pubitemid 44937523)