메뉴 건너뛰기




Volumn 7, Issue 2, 2006, Pages

Characterization of 5-fluorouracil microspheres for colonic delivery

Author keywords

5 FU; Alginate; Colon specific; DSC; Eudragit S 100; HPLC; Microspheres

Indexed keywords

ALGINIC ACID; CALCIUM CHLORIDE; EUDRAGIT; FLUOROURACIL; LIQUID PARAFFIN; MICROSPHERE; SOLVENT; ANTINEOPLASTIC AGENT; DRUG VEHICLE;

EID: 33744899357     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt070231     Document Type: Article
Times cited : (103)

References (28)
  • 1
    • 33745464490 scopus 로고
    • Fluorinated pyrimidine. A new class of tumor inhibitory compounds
    • Heidelberger C, Chaudhuri NK, Danneburg P, et al. Fluorinated pyrimidine. A new class of tumor inhibitory compounds. Nature. 1957;179:663-666.
    • (1957) Nature , vol.179 , pp. 663-666
    • Heidelberger, C.1    Chaudhuri, N.K.2    Danneburg, P.3
  • 2
    • 0015525324 scopus 로고
    • Thymidylate synthetase: Mechanism of inhibition of 5-fluorouracil-2-deoxyuridylate
    • Langenbach RJ, Dancenberg PV, Heidelberger C. Thymidylate synthetase: mechanism of inhibition of 5-fluorouracil-2-deoxyuridylate. Biochem Biophys Res Commun. 1972;48:1565-1571.
    • (1972) Biochem Biophys Res Commun , vol.48 , pp. 1565-1571
    • Langenbach, R.J.1    Dancenberg, P.V.2    Heidelberger, C.3
  • 3
    • 0025611018 scopus 로고
    • Metabolism and mechanism of action of 5-fluorouracil
    • Parker WB, Cheng YC. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol Ther. 1990;48:381-395.
    • (1990) Pharmacol Ther , vol.48 , pp. 381-395
    • Parker, W.B.1    Cheng, Y.C.2
  • 4
    • 0016785582 scopus 로고
    • A double-blind comparison of intensive course 5-fluorouracil by oral vs. intravenous route in the treatment of colorectal carcinoma
    • Hahn RG, Moertel CG, Schutt AJ, Bruckner HW. A double-blind comparison of intensive course 5-fluorouracil by oral vs. intravenous route in the treatment of colorectal carcinoma. Cancer. 1975;35:1031-1035.
    • (1975) Cancer , vol.35 , pp. 1031-1035
    • Hahn, R.G.1    Moertel, C.G.2    Schutt, A.J.3    Bruckner, H.W.4
  • 5
    • 0031017851 scopus 로고    scopus 로고
    • Patient preferences for oral vs intravenous palliative chemotherapy
    • Liu G, Fraussen E, Fitch MI, Warner E. Patient preferences for oral vs intravenous palliative chemotherapy. J Clin Oncol. 1997;15: 110-115.
    • (1997) J Clin Oncol , vol.15 , pp. 110-115
    • Liu, G.1    Fraussen, E.2    Fitch, M.I.3    Warner, E.4
  • 7
  • 8
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet. 1989;16:215-237.
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 9
    • 0037139415 scopus 로고    scopus 로고
    • Colon-specific drug delivery: New approaches and in vitro/in vivo evaluation
    • Yang L, Chu JS, Fix JA. Colon-specific drug delivery: new approaches and in vitro/in vivo evaluation. Int J Pharm. 2002;235:1-15.
    • (2002) Int J Pharm , vol.235 , pp. 1-15
    • Yang, L.1    Chu, J.S.2    Fix, J.A.3
  • 10
    • 0026697912 scopus 로고
    • Calcium alginate beads as core carriers of 5-aminosalicylic acid
    • Shun YL, Ayres JW. Calcium alginate beads as core carriers of 5-aminosalicylic acid. Pharm Res. 1992;9:714-790.
    • (1992) Pharm Res , vol.9 , pp. 714-790
    • Shun, Y.L.1    Ayres, J.W.2
  • 11
    • 0041620130 scopus 로고    scopus 로고
    • In vivo pharmacokinetics in human volunteers: Oral administered guar gum-based colon-targeted 5-fluorouracil tablets
    • Krishnaiah YSR, Satyanarayana V, Kumar DB, Karthikeyan RS, Bhaskar P. In vivo pharmacokinetics in human volunteers: oral administered guar gum-based colon-targeted 5-fluorouracil tablets. Eur J Pharm Sci. 2003;19:355-362.
    • (2003) Eur J Pharm Sci , vol.19 , pp. 355-362
    • Krishnaiah, Y.S.R.1    Satyanarayana, V.2    Kumar, D.B.3    Karthikeyan, R.S.4    Bhaskar, P.5
  • 12
    • 0021130547 scopus 로고
    • Phase I-II trial of high dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer
    • Madajewicz S, Petrelli N, Rustum YM, et. al. Phase I-II trial of high dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer. Cancer Res. 1984;44:4667-4669.
    • (1984) Cancer Res , vol.44 , pp. 4667-4669
    • Madajewicz, S.1    Petrelli, N.2    Rustum, Y.M.3
  • 13
    • 0025378582 scopus 로고
    • Efficiency and toxicity of 5-fluorouracil and folates in advanced colon cancer
    • Cortesi E, Aschelter AM, Gioacchini N, et al. Efficiency and toxicity of 5-fluorouracil and folates in advanced colon cancer. J Chemother. 1990;2:47-50.
    • (1990) J Chemother , vol.2 , pp. 47-50
    • Cortesi, E.1    Aschelter, A.M.2    Gioacchini, N.3
  • 14
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluorouracil and low dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
    • O'Connell MJ, Mailliard JA, Kahn MJ, et al. Controlled trial of fluorouracil and low dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol. 1997;15:246-250.
    • (1997) J Clin Oncol , vol.15 , pp. 246-250
    • O'Connell, M.J.1    Mailliard, J.A.2    Kahn, M.J.3
  • 15
    • 0026499175 scopus 로고
    • The transit rate of different-sized model dosage forms through the human colon and effects of a lactulose induced catharsis
    • Watts PJ, Barrow L, Steed KP, et al. The transit rate of different-sized model dosage forms through the human colon and effects of a lactulose induced catharsis. Int J Pharm. 1992;87: 215-221.
    • (1992) Int J Pharm , vol.87 , pp. 215-221
    • Watts, P.J.1    Barrow, L.2    Steed, K.P.3
  • 16
    • 0005422910 scopus 로고    scopus 로고
    • 5-Fluorouracil-loaded alginate microspheres in chitosan gel for local therapy of breast cancer
    • Muzzarelli RAA, Muzzarelli C, eds. Grottammare, Italy: Atec
    • Calis S, Arica B, Kas HS, Hincal AA. 5-Fluorouracil-loaded alginate microspheres in chitosan gel for local therapy of breast cancer. In: Muzzarelli RAA, Muzzarelli C, eds. Chitosan in Pharmacy and Chemistry. Grottammare, Italy: Atec; 2002:65-69.
    • (2002) Chitosan in Pharmacy and Chemistry , pp. 65-69
    • Calis, S.1    Arica, B.2    Kas, H.S.3    Hincal, A.A.4
  • 18
    • 0029936110 scopus 로고    scopus 로고
    • Long term stability of 5-fluorouracil stored in PVC bags and in ambulatory pump reservoirs
    • Martel P, Petit I, Pinguet S, Poujol S, Astre C, Fabbro M. Long term stability of 5-fluorouracil stored in PVC bags and in ambulatory pump reservoirs. J Pharm Biomed Anal. 1996;14:395-399.
    • (1996) J Pharm Biomed Anal , vol.14 , pp. 395-399
    • Martel, P.1    Petit, I.2    Pinguet, S.3    Poujol, S.4    Astre, C.5    Fabbro, M.6
  • 19
    • 0033014363 scopus 로고    scopus 로고
    • Regulatory aspects of stability testing in Europe
    • Matthews BR. Regulatory aspects of stability testing in Europe. Drug Dev Ind Pharm. 1999;25:831-856.
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 831-856
    • Matthews, B.R.1
  • 20
    • 0024345447 scopus 로고
    • Solid particulates of drug-β-cyclodextrin inclusion complexes directly prepared by a spray-drying technique
    • Lin S, Kao Y. Solid particulates of drug-β-cyclodextrin inclusion complexes directly prepared by a spray-drying technique. Int J Pharm. 1989;56:249-259.
    • (1989) Int J Pharm , vol.56 , pp. 249-259
    • Lin, S.1    Kao, Y.2
  • 21
    • 0031788505 scopus 로고    scopus 로고
    • Preparation and characterization of alginate microspheres containing model antigen
    • Lemoine D, Wauters F, Bouchend S, Preat V. Preparation and characterization of alginate microspheres containing model antigen. Int J Pharm. 1998;176:9-19.
    • (1998) Int J Pharm , vol.176 , pp. 9-19
    • Lemoine, D.1    Wauters, F.2    Bouchend, S.3    Preat, V.4
  • 22
    • 0014592606 scopus 로고
    • Interpretation of percent dissolved-time plots derived from in-vitro testing of conventional tablets and capsules
    • Wagner JG. Interpretation of percent dissolved-time plots derived from in-vitro testing of conventional tablets and capsules. J Pharm Sci. 1969;58:1253-1257.
    • (1969) J Pharm Sci , vol.58 , pp. 1253-1257
    • Wagner, J.G.1
  • 23
    • 0344893332 scopus 로고
    • Mechanism of sustained action medication
    • Higuchi T. Mechanism of sustained action medication. J Pharm Sci. 1963;52:1145-1149.
    • (1963) J Pharm Sci , vol.52 , pp. 1145-1149
    • Higuchi, T.1
  • 25
    • 0000187747 scopus 로고
    • Thermo analysis of microspheres
    • Dubernet C. Thermo analysis of microspheres. Thermochim Acta. 1995;248:259-269.
    • (1995) Thermochim Acta , vol.248 , pp. 259-269
    • Dubernet, C.1
  • 26
    • 0035914220 scopus 로고    scopus 로고
    • Fabrication characterization and in vitro release of paclitaxel (Taxol) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers
    • Mu L, Feng SS. Fabrication characterization and in vitro release of paclitaxel (Taxol) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers. J Control Release. 2001;76:239-254.
    • (2001) J Control Release , vol.76 , pp. 239-254
    • Mu, L.1    Feng, S.S.2
  • 27
    • 0035073301 scopus 로고    scopus 로고
    • Modelling and comparison of dissolution profiles
    • Costa P, Labo JSMS. Modelling and comparison of dissolution profiles. Eur J Pharm Sci. 2001;13:123-133.
    • (2001) Eur J Pharm Sci , vol.13 , pp. 123-133
    • Costa, P.1    Labo, J.S.M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.