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Volumn 143, Issue 1, 2012, Pages 77-84

TLR9-mediated signals rescue B-cells from Fas-induced apoptosis via inactivation of caspases

Author keywords

Apoptosis; B cells; BAFF; Fas; TLR9

Indexed keywords

ABELSON KINASE; B LYMPHOCYTE RECEPTOR; CASPASE; CPG OLIGODEOXYNUCLEOTIDE; FAS ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAFFR; PROTEIN KINASE C; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 84858861935     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2012.02.006     Document Type: Article
Times cited : (14)

References (63)
  • 2
    • 0035671436 scopus 로고    scopus 로고
    • Ligand-dependent and -independent processes in B-cell-receptor-mediated signaling
    • Fuentes-Panana E.M., Monroe J.G. Ligand-dependent and -independent processes in B-cell-receptor-mediated signaling. Springer Semin Immunopathol 2001, 23:333-350.
    • (2001) Springer Semin Immunopathol , vol.23 , pp. 333-350
    • Fuentes-Panana, E.M.1    Monroe, J.G.2
  • 3
    • 0942301195 scopus 로고    scopus 로고
    • Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival
    • Fuentes-Panana E.M., Bannish G., Monroe J.G. Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival. Immunol Rev 2004, 197:26-40.
    • (2004) Immunol Rev , vol.197 , pp. 26-40
    • Fuentes-Panana, E.M.1    Bannish, G.2    Monroe, J.G.3
  • 4
    • 0030938144 scopus 로고    scopus 로고
    • Germinal center development
    • Liu Y.J., Arpin C. Germinal center development. Immunol Rev 1997, 156:111-126.
    • (1997) Immunol Rev , vol.156 , pp. 111-126
    • Liu, Y.J.1    Arpin, C.2
  • 5
    • 0030887835 scopus 로고    scopus 로고
    • Mechanisms of selection and differentiation in germinal centers
    • Liu Y.J., de Bouteiller O., Fugier-Vivier I. Mechanisms of selection and differentiation in germinal centers. Curr Opin Immunol 1997, 9:256-262.
    • (1997) Curr Opin Immunol , vol.9 , pp. 256-262
    • Liu, Y.J.1    de Bouteiller, O.2    Fugier-Vivier, I.3
  • 6
    • 0942268734 scopus 로고    scopus 로고
    • Peripheral B-cell maturation: the intersection of selection and homeostasis
    • Cancro M.P. Peripheral B-cell maturation: the intersection of selection and homeostasis. Immunol Rev 2004, 197:89-101.
    • (2004) Immunol Rev , vol.197 , pp. 89-101
    • Cancro, M.P.1
  • 8
    • 0032795342 scopus 로고    scopus 로고
    • Expression and function of Fas during differentiation and activation of B cells
    • Wang J., Watanabe T. Expression and function of Fas during differentiation and activation of B cells. Int Rev Immunol 1999, 18:367-379.
    • (1999) Int Rev Immunol , vol.18 , pp. 367-379
    • Wang, J.1    Watanabe, T.2
  • 9
    • 0026806777 scopus 로고
    • Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes
    • Lane P., Traunecker A., Hubele S., Inui S., Lanzavecchia A., Gray D. Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes. Eur J Immunol 1992, 22:2573-2578.
    • (1992) Eur J Immunol , vol.22 , pp. 2573-2578
    • Lane, P.1    Traunecker, A.2    Hubele, S.3    Inui, S.4    Lanzavecchia, A.5    Gray, D.6
  • 10
    • 0036634390 scopus 로고    scopus 로고
    • BAFF: a fundamental survival factor for B cells
    • Mackay F., Browning J.L. BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2002, 2:465-475.
    • (2002) Nat Rev Immunol , vol.2 , pp. 465-475
    • Mackay, F.1    Browning, J.L.2
  • 11
    • 70349336151 scopus 로고    scopus 로고
    • B cell receptor and BAFF receptor signaling regulation of B cell homeostasis
    • Khan W.N. B cell receptor and BAFF receptor signaling regulation of B cell homeostasis. J Immunol 2009, 183:3561-3567.
    • (2009) J Immunol , vol.183 , pp. 3561-3567
    • Khan, W.N.1
  • 12
    • 70249086961 scopus 로고    scopus 로고
    • Signalling crosstalk in B cells: managing worth and need
    • Cancro M.P. Signalling crosstalk in B cells: managing worth and need. Nat Rev Immunol 2009, 9:657-661.
    • (2009) Nat Rev Immunol , vol.9 , pp. 657-661
    • Cancro, M.P.1
  • 13
    • 0036667170 scopus 로고    scopus 로고
    • BAFF: a novel therapeutic target for autoimmunity
    • Kalled S.L. BAFF: a novel therapeutic target for autoimmunity. Curr Opin Investig Drugs 2002, 3:1005-1010.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 1005-1010
    • Kalled, S.L.1
  • 14
    • 0029076561 scopus 로고
    • CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells
    • Rathmell J.C., Cooke M.P., Ho W.Y., Grein J., Townsend S.E., Davis M.M., et al. CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature 1995, 376:181-184.
    • (1995) Nature , vol.376 , pp. 181-184
    • Rathmell, J.C.1    Cooke, M.P.2    Ho, W.Y.3    Grein, J.4    Townsend, S.E.5    Davis, M.M.6
  • 15
    • 0029398947 scopus 로고
    • Autoimmunity The Fas track
    • Rathmell J.C., Goodnow C.C. Autoimmunity The Fas track. Curr Biol 1995, 5:1218-1221.
    • (1995) Curr Biol , vol.5 , pp. 1218-1221
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 16
    • 0032775504 scopus 로고    scopus 로고
    • Severe impairment of B cell function in lpr/lpr mice expressing transgenic Fas selectively on B cells
    • Komano H., Ikegami Y., Yokoyama M., Suzuki R., Yonehara S., Yamasaki Y., et al. Severe impairment of B cell function in lpr/lpr mice expressing transgenic Fas selectively on B cells. Int Immunol 1999, 11:1035-1042.
    • (1999) Int Immunol , vol.11 , pp. 1035-1042
    • Komano, H.1    Ikegami, Y.2    Yokoyama, M.3    Suzuki, R.4    Yonehara, S.5    Yamasaki, Y.6
  • 18
    • 0034569391 scopus 로고    scopus 로고
    • Inducible resistance to Fas-mediated apoptosis in B cells
    • Rothstein T.L. Inducible resistance to Fas-mediated apoptosis in B cells. Cell Res 2000, 10:245-266.
    • (2000) Cell Res , vol.10 , pp. 245-266
    • Rothstein, T.L.1
  • 19
    • 0035099037 scopus 로고    scopus 로고
    • Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
    • Takahashi Y., Ohta H., Takemori T. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. Immunity 2001, 14:181-192.
    • (2001) Immunity , vol.14 , pp. 181-192
    • Takahashi, Y.1    Ohta, H.2    Takemori, T.3
  • 20
    • 53349167095 scopus 로고    scopus 로고
    • Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis
    • Hao Z., Duncan G.S., Seagal J., Su Y.W., Hong C., Haight J., et al. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity 2008, 29:615-627.
    • (2008) Immunity , vol.29 , pp. 615-627
    • Hao, Z.1    Duncan, G.S.2    Seagal, J.3    Su, Y.W.4    Hong, C.5    Haight, J.6
  • 23
    • 40149096635 scopus 로고    scopus 로고
    • Integration of signals mediated by B-cell receptor, B-cell activating factor of the tumor necrosis factor family (BAFF) and Fas (CD95)
    • Hancz A., Herincs Z., Neer Z., Sarmay G., Koncz G. Integration of signals mediated by B-cell receptor, B-cell activating factor of the tumor necrosis factor family (BAFF) and Fas (CD95). Immunol Lett 2008, 116:211-217.
    • (2008) Immunol Lett , vol.116 , pp. 211-217
    • Hancz, A.1    Herincs, Z.2    Neer, Z.3    Sarmay, G.4    Koncz, G.5
  • 25
    • 0031572208 scopus 로고    scopus 로고
    • Unmethylated CpG motifs protect murine B lymphocytes against Fas-mediated apoptosis
    • Wang Z., Karras J.G., Colarusso T.P., Foote L.C., Rothstein T.L. Unmethylated CpG motifs protect murine B lymphocytes against Fas-mediated apoptosis. Cell Immunol 1997, 180:162-167.
    • (1997) Cell Immunol , vol.180 , pp. 162-167
    • Wang, Z.1    Karras, J.G.2    Colarusso, T.P.3    Foote, L.C.4    Rothstein, T.L.5
  • 26
    • 0034650517 scopus 로고    scopus 로고
    • Mechanism and function of a newly identified CpG DNA motif in human primary B cells
    • Hartmann G., Krieg A.M. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol 2000, 164:944-953.
    • (2000) J Immunol , vol.164 , pp. 944-953
    • Hartmann, G.1    Krieg, A.M.2
  • 27
    • 0038142387 scopus 로고    scopus 로고
    • A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    • Bernasconi N.L., Onai N., Lanzavecchia A. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 2003, 101:4500-4504.
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 28
    • 40449137383 scopus 로고    scopus 로고
    • CpG drives human transitional B cells to terminal differentiation and production of natural antibodies
    • Capolunghi F., Cascioli S., Giorda E., Rosado M.M., Plebani A., Auriti C., et al. CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. J Immunol 2008, 180:800-808.
    • (2008) J Immunol , vol.180 , pp. 800-808
    • Capolunghi, F.1    Cascioli, S.2    Giorda, E.3    Rosado, M.M.4    Plebani, A.5    Auriti, C.6
  • 29
    • 34247465923 scopus 로고    scopus 로고
    • A novel immunodeficiency characterized by the exclusive presence of transitional B cells unresponsive to CpG
    • Plebani A., Lougaris V., Soresina A., Meini A., Zunino F., Losi C.G., et al. A novel immunodeficiency characterized by the exclusive presence of transitional B cells unresponsive to CpG. Immunology 2007, 121:183-188.
    • (2007) Immunology , vol.121 , pp. 183-188
    • Plebani, A.1    Lougaris, V.2    Soresina, A.3    Meini, A.4    Zunino, F.5    Losi, C.G.6
  • 30
    • 71649101226 scopus 로고    scopus 로고
    • Emerging roles of TLR7 and TLR9 in murine SLE
    • Santiago-Raber M.L., Baudino L., Izui S. Emerging roles of TLR7 and TLR9 in murine SLE. J Autoimmun 2009, 33:231-238.
    • (2009) J Autoimmun , vol.33 , pp. 231-238
    • Santiago-Raber, M.L.1    Baudino, L.2    Izui, S.3
  • 31
    • 44649161194 scopus 로고    scopus 로고
    • The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens
    • Chaturvedi A., Dorward D., Pierce S.K. The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity 2008, 28:799-809.
    • (2008) Immunity , vol.28 , pp. 799-809
    • Chaturvedi, A.1    Dorward, D.2    Pierce, S.K.3
  • 33
    • 0019499829 scopus 로고
    • Quantitative immunofluorescent analysis of surface phenotypes of murine B cell lymphomas and plasmacytomas with monoclonal antibodies
    • Lanier L.L., Warner N.L., Ledbetter J.A., Herzenberg L.A. Quantitative immunofluorescent analysis of surface phenotypes of murine B cell lymphomas and plasmacytomas with monoclonal antibodies. J Immunol 1981, 127:1691-1697.
    • (1981) J Immunol , vol.127 , pp. 1691-1697
    • Lanier, L.L.1    Warner, N.L.2    Ledbetter, J.A.3    Herzenberg, L.A.4
  • 34
    • 0031255312 scopus 로고    scopus 로고
    • B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression
    • Bras A., Martinez A.C., Baixeras E. B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression. J Immunol 1997, 159:3168-3177.
    • (1997) J Immunol , vol.159 , pp. 3168-3177
    • Bras, A.1    Martinez, A.C.2    Baixeras, E.3
  • 35
    • 0141650513 scopus 로고    scopus 로고
    • B cell receptor signaling mediates immediate protection from Fas-induced apoptosis upstream of caspase activation through an atypical protein kinase C isozyme and de novo protein synthesis
    • Hinshaw J.A., Mueller C.M., Scott D.W., Williams M.S. B cell receptor signaling mediates immediate protection from Fas-induced apoptosis upstream of caspase activation through an atypical protein kinase C isozyme and de novo protein synthesis. Eur J Immunol 2003, 33:2490-2500.
    • (2003) Eur J Immunol , vol.33 , pp. 2490-2500
    • Hinshaw, J.A.1    Mueller, C.M.2    Scott, D.W.3    Williams, M.S.4
  • 36
    • 33847684318 scopus 로고    scopus 로고
    • Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes
    • Moriyama H., Yonehara S. Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes. Immunol Lett 2007, 109:36-46.
    • (2007) Immunol Lett , vol.109 , pp. 36-46
    • Moriyama, H.1    Yonehara, S.2
  • 37
    • 0030240678 scopus 로고    scopus 로고
    • Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells
    • Foote L.C., Schneider T.J., Fischer G.M., Wang J.K., Rasmussen B., Campbell K.A., et al. Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells. J Immunol 1996, 157:1878-1885.
    • (1996) J Immunol , vol.157 , pp. 1878-1885
    • Foote, L.C.1    Schneider, T.J.2    Fischer, G.M.3    Wang, J.K.4    Rasmussen, B.5    Campbell, K.A.6
  • 39
    • 18844380660 scopus 로고    scopus 로고
    • Signaling in B cells via Toll-like receptors
    • Peng S.L. Signaling in B cells via Toll-like receptors. Curr Opin Immunol 2005, 17:230-236.
    • (2005) Curr Opin Immunol , vol.17 , pp. 230-236
    • Peng, S.L.1
  • 40
    • 69449095860 scopus 로고    scopus 로고
    • Caspases and kinases in a death grip
    • Kurokawa M., Kornbluth S. Caspases and kinases in a death grip. Cell 2009, 138:838-854.
    • (2009) Cell , vol.138 , pp. 838-854
    • Kurokawa, M.1    Kornbluth, S.2
  • 41
    • 15744398903 scopus 로고    scopus 로고
    • C-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
    • Raina D., Pandey P., Ahmad R., Bharti A., Ren J., Kharbanda S., et al. c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem 2005, 280:11147-11151.
    • (2005) J Biol Chem , vol.280 , pp. 11147-11151
    • Raina, D.1    Pandey, P.2    Ahmad, R.3    Bharti, A.4    Ren, J.5    Kharbanda, S.6
  • 42
    • 0034689031 scopus 로고    scopus 로고
    • Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL
    • Horita M., Andreu E.J., Benito A., Arbona C., Sanz C., Benet I., et al. Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL. J Exp Med 2000, 191:977-984.
    • (2000) J Exp Med , vol.191 , pp. 977-984
    • Horita, M.1    Andreu, E.J.2    Benito, A.3    Arbona, C.4    Sanz, C.5    Benet, I.6
  • 43
    • 33646858146 scopus 로고    scopus 로고
    • Imatinib mesylate--uncovering a fast track to adaptive immunity
    • Smyth M.J. Imatinib mesylate--uncovering a fast track to adaptive immunity. N Engl J Med 2006, 354:2282-2284.
    • (2006) N Engl J Med , vol.354 , pp. 2282-2284
    • Smyth, M.J.1
  • 46
    • 33646542701 scopus 로고    scopus 로고
    • Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression
    • Cursi S., Rufini A., Stagni V., Condo I., Matafora V., Bachi A., et al. Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression. Embo J 2006, 25:1895-1905.
    • (2006) Embo J , vol.25 , pp. 1895-1905
    • Cursi, S.1    Rufini, A.2    Stagni, V.3    Condo, I.4    Matafora, V.5    Bachi, A.6
  • 47
    • 0025875259 scopus 로고
    • Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen P.L., Eisenberg R.A. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1991, 9:243-269.
    • (1991) Annu Rev Immunol , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 48
    • 0033989612 scopus 로고    scopus 로고
    • Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP
    • Wang J., Lobito A.A., Shen F., Hornung F., Winoto A., Lenardo M.J. Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP. Eur J Immunol 2000, 30:155-163.
    • (2000) Eur J Immunol , vol.30 , pp. 155-163
    • Wang, J.1    Lobito, A.A.2    Shen, F.3    Hornung, F.4    Winoto, A.5    Lenardo, M.J.6
  • 49
    • 0033559247 scopus 로고    scopus 로고
    • A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes
    • Schneider T.J., Fischer G.M., Donohoe T.J., Colarusso T.P., Rothstein T.L. A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes. J Exp Med 1999, 189:949-956.
    • (1999) J Exp Med , vol.189 , pp. 949-956
    • Schneider, T.J.1    Fischer, G.M.2    Donohoe, T.J.3    Colarusso, T.P.4    Rothstein, T.L.5
  • 50
    • 0033197968 scopus 로고    scopus 로고
    • Cutting edge: a novel mechanism for rescue of B cells from CD95/Fas-mediated apoptosis
    • Catlett I.M., Bishop G.A. Cutting edge: a novel mechanism for rescue of B cells from CD95/Fas-mediated apoptosis. J Immunol 1999, 163:2378-2381.
    • (1999) J Immunol , vol.163 , pp. 2378-2381
    • Catlett, I.M.1    Bishop, G.A.2
  • 51
    • 0035976906 scopus 로고    scopus 로고
    • Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis
    • Gomez-Angelats M., Cidlowski J.A. Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis. J Biol Chem 2001, 276:44944-44952.
    • (2001) J Biol Chem , vol.276 , pp. 44944-44952
    • Gomez-Angelats, M.1    Cidlowski, J.A.2
  • 52
    • 78149275614 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression
    • Lim E.J., Park D.W., Lee J.G., Lee C.H., Bae Y.S., Hwang Y.C., et al. Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression. Exp Mol Med 2010, 42:712-720.
    • (2010) Exp Mol Med , vol.42 , pp. 712-720
    • Lim, E.J.1    Park, D.W.2    Lee, J.G.3    Lee, C.H.4    Bae, Y.S.5    Hwang, Y.C.6
  • 53
    • 33846000664 scopus 로고    scopus 로고
    • CpG-B oligodeoxynucleotide promotes cell survival via up-regulation of Hsp70 to increase Bcl-xL and to decrease apoptosis-inducing factor translocation
    • Kuo C.C., Liang S.M., Liang C.M. CpG-B oligodeoxynucleotide promotes cell survival via up-regulation of Hsp70 to increase Bcl-xL and to decrease apoptosis-inducing factor translocation. J Biol Chem 2006, 281:38200-38207.
    • (2006) J Biol Chem , vol.281 , pp. 38200-38207
    • Kuo, C.C.1    Liang, S.M.2    Liang, C.M.3
  • 54
    • 0142242113 scopus 로고    scopus 로고
    • CD4+CD25+ T cells lyse antigen-presenting B cells by Fas-Fas ligand interaction in an epitope-specific manner
    • Janssens W., Carlier V., Wu B., VanderElst L., Jacquemin M.G., Saint-Remy J.M. CD4+CD25+ T cells lyse antigen-presenting B cells by Fas-Fas ligand interaction in an epitope-specific manner. J Immunol 2003, 171:4604-4612.
    • (2003) J Immunol , vol.171 , pp. 4604-4612
    • Janssens, W.1    Carlier, V.2    Wu, B.3    VanderElst, L.4    Jacquemin, M.G.5    Saint-Remy, J.M.6
  • 55
    • 0028920079 scopus 로고
    • Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells
    • Rothstein T.L., Wang J.K., Panka D.J., Foote L.C., Wang Z., Stanger B., et al. Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 1995, 374:163-165.
    • (1995) Nature , vol.374 , pp. 163-165
    • Rothstein, T.L.1    Wang, J.K.2    Panka, D.J.3    Foote, L.C.4    Wang, Z.5    Stanger, B.6
  • 56
    • 0028865583 scopus 로고
    • CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway
    • Schattner E.J., Elkon K.B., Yoo D.H., Tumang J., Krammer P.H., Crow M.K., et al. CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway. J Exp Med 1995, 182:1557-1565.
    • (1995) J Exp Med , vol.182 , pp. 1557-1565
    • Schattner, E.J.1    Elkon, K.B.2    Yoo, D.H.3    Tumang, J.4    Krammer, P.H.5    Crow, M.K.6
  • 57
    • 9344234460 scopus 로고    scopus 로고
    • IL-4 and anti-CD40 protect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation
    • Nakanishi K., Matsui K., Kashiwamura S., Nishioka Y., Nomura J., Nishimura Y., et al. IL-4 and anti-CD40 protect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation. Int Immunol 1996, 8:791-798.
    • (1996) Int Immunol , vol.8 , pp. 791-798
    • Nakanishi, K.1    Matsui, K.2    Kashiwamura, S.3    Nishioka, Y.4    Nomura, J.5    Nishimura, Y.6
  • 58
    • 0037178853 scopus 로고    scopus 로고
    • Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL
    • Wurster A.L., Rodgers V.L., White M.F., Rothstein T.L., Grusby M.J. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem 2002, 277:27169-27175.
    • (2002) J Biol Chem , vol.277 , pp. 27169-27175
    • Wurster, A.L.1    Rodgers, V.L.2    White, M.F.3    Rothstein, T.L.4    Grusby, M.J.5
  • 59
    • 27944476444 scopus 로고    scopus 로고
    • BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway
    • Craxton A., Draves K.E., Gruppi A., Clark E.A. BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway. J Exp Med 2005, 202:1363-1374.
    • (2005) J Exp Med , vol.202 , pp. 1363-1374
    • Craxton, A.1    Draves, K.E.2    Gruppi, A.3    Clark, E.A.4
  • 61
    • 80054875478 scopus 로고    scopus 로고
    • Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease
    • Rickert R.C., Jellusova J., Miletic A.V. Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease. Immunol Rev 2011, 244:115-133.
    • (2011) Immunol Rev , vol.244 , pp. 115-133
    • Rickert, R.C.1    Jellusova, J.2    Miletic, A.V.3
  • 62
    • 0030812046 scopus 로고    scopus 로고
    • Unmethylated CpG-containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step
    • Macfarlane D.E., Manzel L., Krieg A.M. Unmethylated CpG-containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step. Immunology 1997, 91:586-593.
    • (1997) Immunology , vol.91 , pp. 586-593
    • Macfarlane, D.E.1    Manzel, L.2    Krieg, A.M.3
  • 63
    • 70449411507 scopus 로고    scopus 로고
    • Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo
    • Fraser C.K., Lousberg E.L., Kumar R., Hughes T.P., Diener K.R., Hayball J.D. Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo. Exp Hematol 2009, 37:1435-1444.
    • (2009) Exp Hematol , vol.37 , pp. 1435-1444
    • Fraser, C.K.1    Lousberg, E.L.2    Kumar, R.3    Hughes, T.P.4    Diener, K.R.5    Hayball, J.D.6


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