Detoxification of G-and V-series nerve agents by the phosphotriesterase OpdA

Biocatalysis and Biotransformation

Volumn 30, Issue 2, 2012, Pages 203-208

  Wille, Timo ^a   Scott, Colin ^b   Thiermann, Horst ^a   Worek, Franz ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b CSIRO   (Australia)

Author keywords

Human cholinesterase; In vitro kinetics; OP nerve toxins; Organophosphate

Indexed keywords

ANIMAL MODEL; CYCLOSARIN; DIRECTED EVOLUTION; ENZYME ENGINEERING; HUMAN CHOLINESTERASE; IN-VITRO; LEAVING GROUPS; NERVE AGENTS; OP NERVE TOXINS; ORGANOPHOSPHATE; ORGANOPHOSPHOROUS; PHOSPHOTRIESTERASES; REACTION MECHANISM; V-SERIES;

DETOXIFICATION; ENZYMES; INSECTICIDES; METABOLITES;

VANADIUM;

CYCLOSARIN; INSECTICIDE; ORGANOPHOSPHOROUS DEGRADING ENZYME; ORGANOPHOSPHORUS COMPOUND; PHOSPHOTRIESTERASE; SOMAN; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; CHEMICAL STRUCTURE; DETOXIFICATION; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME KINETICS; ENZYME MECHANISM; HYDROLYSIS; IN VITRO STUDY; REACTION ANALYSIS; STOICHIOMETRY;

ANIMALIA;

EID: 84858857296     PISSN: 10242422     EISSN: 10292446     Source Type: Journal    
DOI: 10.3109/10242422.2012.661724     Document Type: Article

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