Freeform fabricated scaffolds with roughened struts that enhance both stem cell proliferation and differentiation by controlling cell shape

Biomaterials

Volumn 33, Issue 16, 2012, Pages 4022-4030

  Kumar, Girish ^a,b,c   Waters, Michael S ^a   Farooque, Tanya M ^a   Young, Marian F ^b   Simon, Carl G ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c CENTER FOR DEVICES AND RADIOLOGICAL HEALTH   (United States)

Author keywords

Cell proliferation; Cell spreading; Osteogenesis; Scaffold; Stem cell; Topography

Indexed keywords

BONE-LIKE TISSUE; CAPROLACTONE; CELL FUNCTIONS; CELL MORPHOLOGY; CELL SHAPES; CELL SPREADING; FREEFORMS; NANOFIBER SCAFFOLD; OSTEOGENESIS; OSTEOGENIC DIFFERENTIATION; SCAFFOLD FABRICATION; SOLVENT ETCHING;

BONE; CELL CULTURE; CELL PROLIFERATION; FABRICATION; NANOFIBERS; RATIONAL FUNCTIONS; SCAFFOLDS; STEM CELLS; STRUTS; SURFACE ROUGHNESS; TISSUE; TOPOGRAPHY;

SCAFFOLDS (BIOLOGY);

FREEFORM FABRICATED SCAFFOLD; MOLECULAR SCAFFOLD; NANOFIBER; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HYPOTHESIS; MORPHOLOGY; PRIORITY JOURNAL; TOPOGRAPHY; VALIDATION PROCESS;

BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; OSTEOCALCIN; STEM CELLS; SURFACE PROPERTIES;

EID: 84858800104     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.02.048     Document Type: Article

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