NADPH oxidase-derived superoxide destabilizes lipopolysaccharide-induced interleukin 8 mRNA via p38, extracellular signal-regulated kinase mitogen-activated protein kinase, and the destabilizing factor tristetraprolin

Shock

Volumn 37, Issue 4, 2012, Pages 433-440

  Al Ghouleh, Imad ^a   Magder, Sheldon ^a  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

endotoxin; ERK; HUVEC; ICAM 1; interleukin 6; interleukin 8; LPS; p22 phox; p38 MAPK; reactive oxygen species; TNF ; tristetraprolin

Indexed keywords

ACETYLCYSTEINE; DIPHENYLIODONIUM SALT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; SUPEROXIDE; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA STABILITY; UMBILICAL VEIN ENDOTHELIAL CELL;

BLOTTING, NORTHERN; BLOTTING, WESTERN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPEROXIDES; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84858796265     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31824582e6     Document Type: Article

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