Detection of asymptomatic nigrostriatal dopaminergic lesion in rats by exhaled air analysis using carbon nanotube sensors

ACS Chemical Neuroscience

Volumn 3, Issue 3, 2012, Pages 161-166

  Tisch, Ulrike ^a   Aluf, Yuval ^a   Ionescu, Radu ^a   Nakhleh, Morad ^a   Bassal, Rana ^a   Axelrod, Noa ^a   Robertman, Dorina ^a   Tessler, Yael ^a   Finberg, John P M ^a   Haick, Hossam ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

breath analysis; early diagnosis; nanomaterial; Parkinsonism; sensor; volatile organic compound

Indexed keywords

CARBON NANOTUBE; HEXADECANE; STYRENE; VOLATILE ORGANIC COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASYMPTOMATIC DISEASE; BREATH ANALYSIS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DISEASE CLASSIFICATION; DISEASE MARKER; DOPAMINERGIC NERVE CELL; EARLY DIAGNOSIS; EXPIRED AIR; FACTORIAL ANALYSIS; MALE; MASS FRAGMENTOGRAPHY; NANOSENSOR; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; SHAM PROCEDURE; STATISTICAL SIGNIFICANCE; SUBSTANTIA NIGRA;

BREATH ANALYSIS; EARLY DIAGNOSIS; NANOMATERIAL; PARKINSONISM; SENSOR; VOLATILE ORGANIC COMPOUND;

AIR; ANIMALS; BREATH TESTS; DOPAMINE; DOPAMINERGIC NEURONS; EXHALATION; MALE; NANOTUBES, CARBON; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA;

RATTUS;

EID: 84858784264     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn200093r     Document Type: Article

References (40)

1. Wright, W. A., Evanoff, B. A., Lian, M., Criswell, S. R., and Racette, B. A. (2010) Geographic and ethnic variation in Parkinson disease: A population-based study of US medicare beneficiaries Neuroepidemiology 34, 143-151
2. de Rijk, M. C., Launer, L. J., Berger, K., Breteler, M. M., Dartigues, J. F., Baldereschi, M., Fratiglioni, L., Lobo, A., Martinez-Lage, J., Trenkwalder, C., and Hofman, A. (2000) Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts Neurology 54, S21-S23
3. Lozano, A. M. and Kalia, S. K. (2005) New movement in Parkinson's Sci. Am. 293, 68-75 (Pubitemid 40920763)
4. Braak, H., Del Tredici, K., Rub, U., de Vos, R. A., Jansen Steur, E. N., and Braak, E. (2003) Staging of brain pathology related to sporadic Parkinson's disease Neurobiol. Aging 24, 197-211 (Pubitemid 36007810)
5. Schrag, A., Ben-Shlomo, Y., and Quinn, N. (2002) How valid is the clinical diagnosis of Parkinson's disease in the community? J. Neurol. Neurosurg. Psychiatry 73, 529-534 (Pubitemid 35246805)
6. Goetz, C. G., Tilley, B. C., Shaftman, S. R., Stebbins, G. T., Fahn, S., Martinez-Martin, P., Poewe, W., Sampaio, C., Stern, M. B., Dodel, R., Dubois, B., Holloway, R., Jankovic, J., Kulisevsky, J., Lang, A. E., Lees, A., Leurgans, S., LeWitt, P. A., Nyenhuis, D., Olanow, C. W., Rascol, O., Schrag, A., Teresi, J. A., van Hilten, J. J., and LaPelle, N. (2008) Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS): Scale presentation and clinimetric testing results Mov. Disord. 23, 2129-2170
7. Poewe, W. (2008) Non-motor dymptoms in Parkinson's disease Eur. J. Neurol. 1, 14-20
8. Bezard, E., Gross, C. E., and Brotchie, J. M. (2003) Presymptomatic compensation in Parkinson's disease is not dopamine-mediated Trends Neurosci. 26, 215-221 (Pubitemid 36412004)
9. Bogdanov, M., Matson, W. R., Wang, L., Matson, T., Saunders-Pullman, R., Bressman, S. S., and Flint Beal, M. (2008) Metabolomic profiling to develop blood biomarkers for Parkinson's disease Brain 131, 389-396 (Pubitemid 351197614)
10. Coetsee, T. N., Pretorius, P. J., Terre'blanche, G., and Bergh, J. J. (2008) Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum Food Chem. Toxicol. 46, 3186-3192
11. Ahmed, S. S., Santosh, W., Kumar, S., and Christlet, H. T. T. (2009) Metabolic profiling of parkinson's disease: Evidence of biomarker from gene expression analysis and rapid neural network detection J. Biomed. Sci. 16, 63
12. Michell, A. W., Mosedale, D., Grainger, J. D., and Barker, R. A. (2008) Metabolomic analysis of urine and serum in Parkinson's disease Metabolomics 4, 191-201
13. Quinones, M. P. and Kaddurah-Daouk, R. (2009) Metabolomics tools for identifying biomarkers for neuropsychiatric diseases Neurobiol. Dis. 35, 165-176
14. Barba, I., Fernandez-Montesinos, R., Garcia-Dorado, D., and Pozo, D. (2008) Alzheimer's disease beyond the genomic rra: Nuclear magnetic resonance (NMR) spectroscopy-based metabolomics J. Cell Mol. Med. 12, 1477-1485
15. Greenberg, N., Grassan, A., Thambisetty, M., Lovestone, S., and Legido-Quigley, C. (2009) A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease Electrophoresis 30, 1235-1239
16. Baykal, A. T., Jain, M. R., and Li, H. (2008) Aberrant regulation of choline metabolism by mitochondrial electron transport system inhibition in neuroblastoma cells Metabolomics 4, 347-356
17. Tisch, U. and Haick, H. (2010) Nanomaterials for cross-reactive sensor arrays MRS Bull. 35, 797-803
18. Tisch, U. and Haick, H. (2011) Arrays of chemisensitive monolayer-capped metallic nanoparticles for diagnostic breath testing Rev. Chem. Eng. 26, 171-179
19. Peng, G., Tisch, U., Adams, O., Hakim, M., Shehada, N., Broza, Y. Y., Billan, S., Abdah-Bortnyak, R., Kuten, A., and Haick, H. (2009) Diagnosing lung cancer in exhaled breath using gold nanoparticles Nat. Nanotechnol. 4, 669-673
20. Peng, G., Hakim, M., Broza, Y. Y., Billan, S., Abdah-Bortnyak, R., Kuten, A., Tisch, U., and Haick, H. (2010) Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors Br. J. Cancer 103, 542-551
21. Shuster, G., Gallimidi, Z., Heyman-Reiss, A., Dovgolevsky, E., Billan, S., Abdah-Bortnyak, R., Kuten, A., Engel, A., Shiban, A., Tisch, U., and Haick, H. (2010) Classification of breast cancer precursors through exhaled breath Breast Cancer Res. Treat. 126, 791-796
22. Amann, A., Spaněl, P., and Smith, D. (2007) Breath analysis: The approach towards clinical applications Mini-Rev. Med. Chem. 7, 115-129 (Pubitemid 46592175)
23. Cao, W. and Duan, Y. (2007) Current status of methods and techniques for breath analysis Crit. Rev. Anal. Chem. 37, 3-13 (Pubitemid 46351780)
24. Ionescu, R., Broza, Y., Shaltieli, H., Sadeh, D., Zilberman, Y., Feng, X., Glass-Marmor, L., Lejbkowicz, I., Müllen, K., Miller, A., and Haick, H. (2011) Detection of Multiple Sclerosis from exhaled breath using bilayers of polycyclic aromatic hydrocarbons and single-wall carbon nanotubes ACS Chem. Neurosci. 2, 687-693
25. Haick, H., Hakim, M., Patrascu, M., Levenberg, C., Shehada, N., Nakhoul, F., and Abassi, Z. (2009) Sniffing chronic renal failure in rat model by an array of random networks of single-walled carbon nanotubes ACS Nano 3, 1258-1266
26. Hakim, M., Billan, S., Tisch, U., Peng, G., Dvrokind, I., Marom, O., Abdah-Bortnyak, R., Kuten, A., and Haick, H. (2011) Diagnosis of head-and-neck cancer from exhaled breath Br. J. Cancer 104, 1649-1655
27. Peng, G., Trock, E., and Haick, H. (2008) Detecting simulated patterns of lung cancer biomarkers by random network of single-walled carbon nanotubes coated with nonpolymeric organic materials Nano Lett. 8, 3631-3635
28. Aluf, Y., Vaya, J., Khatib, S., and Finberg, J. P. (2011) Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule Neuropharmacology 61, 87-94
29. Aluf, Y., Vaya, J., Khatib, S., Loboda, Y., Kizhner, S., and Finberg, J. P. (2010) Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule Free Rad. Res. 44, 635-644
30. Zigmond, M. J., Abercrombie, E. D., Berger, T. W., Grace, A. A., and Stricker, E. M. (1990) Compensations after lesions of central dopaminergic neurons: Some clinical and basic implications Trends Neurosci. 13, 290-296 (Pubitemid 20193461)
31. Jenner, P. (2003) Oxidative stress in Parkinson's disease Ann. Neurol. 53, S26-S38
32. Terre'Blanche, G., Heyer, N., Bergh, J. J., Mienie, L. J., van der Schyf, C. J., and Harvey, B. H. (2011) The styrene metabolite, phenylglyoxylic acid, induces striatal-motor toxicity in the rat: Influence of dose escalation/reduction over time Neurotox. Res. 20, 97-101
33. Wongvijitsuk, S., Navasumrit, P., Vattanasit, U., Parnlob, V., and Ruchirawat, M. (2011) Low level occupational exposure to styrene: Its effects on DNA damage and DNA repair Int. J. Hyg. Environ. Health 214, 127-137
34. Peng, G., Tisch, U., and Haick, H. (2009) Detection of nonpolar molecules by means of carrier scattering in random networks of carbon nanotubes: Toward diagnosis of diseases via breath samples Nano Lett. 9, 1362-1368
35. Zilberman, Y., Tisch, U., Shuster, G., Pisula, W., Feng, X., Müllen, K., and Haick, H. (2010) Carbon nanotube/hexa-peri-hexabenzocoronene bilayers for discrimination between nonpolar volatile organic compounds of cancer and humid atmospheres Adv. Mater. 22, 4317-4320
36. Kushch, I., Schwarz, K., Schwentner, L., Baumann, B., Dzien, A., Schmid, A., Unterkofler, K., Gastl, G., Španel, P., Smith, D., and Amann, A. (2008) Compounds enhanced in a mass spectrometric profile of smokers' exhaled breath versus non-smokers as determined in a pilot study using PTR-MS J. Breath Res. 2, 026002
37. Dovgolevsky, E., Konvalina, G., Tisch, U., and Haick, H. (2010) Monolayer-capped cubic platinum nanoparticles for sensing nonpolar analytes in highly humid atmospheres J. Phys. Chem. C 114, 14042-14049
38. Dovgolevsky, E., Tisch, U., and Haick, H. (2009) Chemically sensitive resistors based on monolayer-capped cubic nanoparticles: towards configurable nanoporous sensors Small 5, 1158-1161
39. 2 in the presence of CO using a single tungsten oxide semiconductor sensor and dynamic signal processing Analyst 127, 1237-1246
40. Brereton, R. G. (1990) Chemometrics, Application of Mathematics Statistics to Laboratory Systems, Ellis Horwood, Chichester.