메뉴 건너뛰기




Volumn 114, Issue , 2012, Pages 107-149

Malaria Vaccine Development Using Synthetic Peptides as a Technical Platform

Author keywords

Clinical trials; Immune response; Long Synthetic peptides; Malaria; Peptide synthesis; Vaccine

Indexed keywords

ALUMINUM HYDROXIDE; GLUTAMIC ACID; GLUTAMIC ACID RICH PROTEIN; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 1; MEROZOITE SURFACE PROTEIN 2; MEROZOITE SURFACE PROTEIN 3 VACCINE; MONTANIDE ISA 51; SPF 66 VACCINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

EID: 84858773353     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/B978-0-12-396548-6.00005-6     Document Type: Chapter
Times cited : (11)

References (217)
  • 4
  • 5
    • 0031929115 scopus 로고    scopus 로고
    • Mapping and comparison of the B-cell epitopes recognized on the Plasmodium vivax circumsporozoite protein by immune Colombians and immunized Aotus monkeys
    • Arevalo-Herrera M., Roggero M.A., Gonzalez J.M., Vergara J., Corradin G., Lopez J.A., Herrera S. Mapping and comparison of the B-cell epitopes recognized on the Plasmodium vivax circumsporozoite protein by immune Colombians and immunized Aotus monkeys. Ann. Trop. Med. Parasitol. 1998, 92(5):539-551.
    • (1998) Ann. Trop. Med. Parasitol. , vol.92 , Issue.5 , pp. 539-551
    • Arevalo-Herrera, M.1    Roggero, M.A.2    Gonzalez, J.M.3    Vergara, J.4    Corradin, G.5    Lopez, J.A.6    Herrera, S.7
  • 7
    • 85046915641 scopus 로고    scopus 로고
    • Current status of Plasmodium vivax vaccine
    • Arevalo-Herrera M., Chitnis C., Herrera S. Current status of Plasmodium vivax vaccine. Hum. Vaccin. 2010, 6(1):124-132.
    • (2010) Hum. Vaccin. , vol.6 , Issue.1 , pp. 124-132
    • Arevalo-Herrera, M.1    Chitnis, C.2    Herrera, S.3
  • 8
    • 79952470466 scopus 로고    scopus 로고
    • Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein
    • Arevalo-Herrera M., Soto L., Perlaza B.L., Cespedes N., Vera O., Lenis A.M., Bonelo A., Corradin G., Herrera S. Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein. Am. J. Trop. Med. Hyg. 2011, 84(2 Suppl.):35-42.
    • (2011) Am. J. Trop. Med. Hyg. , vol.84 , Issue.2 SUPPL. , pp. 35-42
    • Arevalo-Herrera, M.1    Soto, L.2    Perlaza, B.L.3    Cespedes, N.4    Vera, O.5    Lenis, A.M.6    Bonelo, A.7    Corradin, G.8    Herrera, S.9
  • 9
    • 79952459523 scopus 로고    scopus 로고
    • Preclinical vaccine study of Plasmodium vivax circumsporozoite protein derived-synthetic polypeptides formulated in montanide ISA 720 and montanide ISA 51 adjuvants
    • Arevalo-Herrera M., Vera O., Castellanos A., Cespedes N., Soto L., Corradin G., Herrera S. Preclinical vaccine study of Plasmodium vivax circumsporozoite protein derived-synthetic polypeptides formulated in montanide ISA 720 and montanide ISA 51 adjuvants. Am. J. Trop. Med. Hyg. 2011, 84(2 Suppl.):21-27.
    • (2011) Am. J. Trop. Med. Hyg. , vol.84 , Issue.2 SUPPL. , pp. 21-27
    • Arevalo-Herrera, M.1    Vera, O.2    Castellanos, A.3    Cespedes, N.4    Soto, L.5    Corradin, G.6    Herrera, S.7
  • 11
    • 0022374357 scopus 로고
    • Circumsporozoite protein of Plasmodium vivax: Gene cloning and characterization of the immunodominant epitope
    • Arnot D.E., Barnwell J.W., Tam J.P., Nussenzweig V., Nussenzweig R.S., Enea V. Circumsporozoite protein of Plasmodium vivax: Gene cloning and characterization of the immunodominant epitope. Science 1985, 230(4727):815-818.
    • (1985) Science , vol.230 , Issue.4727 , pp. 815-818
    • Arnot, D.E.1    Barnwell, J.W.2    Tam, J.P.3    Nussenzweig, V.4    Nussenzweig, R.S.5    Enea, V.6
  • 13
    • 28444478057 scopus 로고    scopus 로고
    • Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen
    • Audran R., Cachat M., Lurati F., Soe S., Leroy O., Corradin G., Druilhe P., Spertini F. Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen. Infect. Immun. 2005, 73(12):8017-8026.
    • (2005) Infect. Immun. , vol.73 , Issue.12 , pp. 8017-8026
    • Audran, R.1    Cachat, M.2    Lurati, F.3    Soe, S.4    Leroy, O.5    Corradin, G.6    Druilhe, P.7    Spertini, F.8
  • 14
    • 70350135532 scopus 로고    scopus 로고
    • The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: A randomized controlled phase I trial
    • Audran R., Lurati-Ruiz F., Genton B., Blythman H.E., Ofori-Anyinam O., Reymond C., Corradin G., Spertini F. The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: A randomized controlled phase I trial. PLoS One 2009, 4(10):e7304.
    • (2009) PLoS One , vol.4 , Issue.10
    • Audran, R.1    Lurati-Ruiz, F.2    Genton, B.3    Blythman, H.E.4    Ofori-Anyinam, O.5    Reymond, C.6    Corradin, G.7    Spertini, F.8
  • 15
    • 0025777095 scopus 로고
    • Age-dependent acquired protection against Plasmodium falciparum in people having two years exposure to hyperendemic malaria
    • Baird J.K., Jones T.R., Danudirgo E.W., Annis B.A., Bangs M.J., Basri H., Purnomo, Masbar S. Age-dependent acquired protection against Plasmodium falciparum in people having two years exposure to hyperendemic malaria. Am. J. Trop. Med. Hyg. 1991, 45(1):65-76.
    • (1991) Am. J. Trop. Med. Hyg. , vol.45 , Issue.1 , pp. 65-76
    • Baird, J.K.1    Jones, T.R.2    Danudirgo, E.W.3    Annis, B.A.4    Bangs, M.J.5    Basri, H.6    Purnomo7    Masbar, S.8
  • 16
    • 17344367919 scopus 로고    scopus 로고
    • Age-dependent susceptibility to severe disease with primary exposure to Plasmodium falciparum
    • Baird J.K., Masbar S., Basri H., Tirtokusumo S., Subianto B., Hoffman S.L. Age-dependent susceptibility to severe disease with primary exposure to Plasmodium falciparum. J. Infect. Dis. 1998, 178(2):592-595.
    • (1998) J. Infect. Dis. , vol.178 , Issue.2 , pp. 592-595
    • Baird, J.K.1    Masbar, S.2    Basri, H.3    Tirtokusumo, S.4    Subianto, B.5    Hoffman, S.L.6
  • 18
    • 85173705922 scopus 로고
    • über ein allgemeinesVerfahren der peptid-synthese
    • Bergman M., Zervas L. über ein allgemeinesVerfahren der peptid-synthese. Ber. Dtsch. Chem. Ges. 1932, 65:1192-1201.
    • (1932) Ber. Dtsch. Chem. Ges. , vol.65 , pp. 1192-1201
    • Bergman, M.1    Zervas, L.2
  • 19
    • 84857444327 scopus 로고    scopus 로고
    • Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor
    • [Epub ahead of print]
    • Bernabeu M., Lopez F.J., Ferrer M., Martin-Jaular L., Razaname A., Corradin G., Maier A.G., del Portillo H.A., Fernandez-Becerra C. Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor. Cell. Microbiol. 2011, [Epub ahead of print]. 10.1111/j.1462-5822.2011.01726.x.
    • (2011) Cell. Microbiol.
    • Bernabeu, M.1    Lopez, F.J.2    Ferrer, M.3    Martin-Jaular, L.4    Razaname, A.5    Corradin, G.6    Maier, A.G.7    del Portillo, H.A.8    Fernandez-Becerra, C.9
  • 20
    • 0028983853 scopus 로고
    • Stabilization of type-I beta-turn conformations in peptides containing the npna-repeat motif of the plasmodium-falciparum circumsporozoite protein by substituting proline for (S)-alpha-methylproline
    • Bisang C., Weber C., Inglis J., Schiffer C.A., Vangunsteren W.F., Jelesarov I., Bosshard H.R., Robinson J.A. Stabilization of type-I beta-turn conformations in peptides containing the npna-repeat motif of the plasmodium-falciparum circumsporozoite protein by substituting proline for (S)-alpha-methylproline. J. Am. Chem. Soc. 1995, 117(30):7904-7915.
    • (1995) J. Am. Chem. Soc. , vol.117 , Issue.30 , pp. 7904-7915
    • Bisang, C.1    Weber, C.2    Inglis, J.3    Schiffer, C.A.4    Vangunsteren, W.F.5    Jelesarov, I.6    Bosshard, H.R.7    Robinson, J.A.8
  • 21
    • 0032486772 scopus 로고    scopus 로고
    • Synthesis, conformational properties, and immunogenicity of a cyclic template-bound peptide mimetic containing an NPNA motif from the circumsporozoite protein of Plasmodium falciparum
    • Bisang C., Jiang L.Y., Freund E., Emery F., Bauch C., Matile H., Pluschke G., Robinson J.A. Synthesis, conformational properties, and immunogenicity of a cyclic template-bound peptide mimetic containing an NPNA motif from the circumsporozoite protein of Plasmodium falciparum. J. Am. Chem. Soc. 1998, 120(30):7439-7449.
    • (1998) J. Am. Chem. Soc. , vol.120 , Issue.30 , pp. 7439-7449
    • Bisang, C.1    Jiang, L.Y.2    Freund, E.3    Emery, F.4    Bauch, C.5    Matile, H.6    Pluschke, G.7    Robinson, J.A.8
  • 23
    • 0001703616 scopus 로고
    • Synthesis of peptides by aminolysis of nitrophenyl esters
    • Bodanszky M. Synthesis of peptides by aminolysis of nitrophenyl esters. Nature 1955, 175(4459):685.
    • (1955) Nature , vol.175 , Issue.4459 , pp. 685
    • Bodanszky, M.1
  • 24
    • 0025606095 scopus 로고
    • Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes
    • Bouharoun-Tayoun H., Attanath P., Sabchareon A., Chongsuphajaisiddhi T., Druilhe P. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J. Exp. Med. 1990, 172(6):1633-1641.
    • (1990) J. Exp. Med. , vol.172 , Issue.6 , pp. 1633-1641
    • Bouharoun-Tayoun, H.1    Attanath, P.2    Sabchareon, A.3    Chongsuphajaisiddhi, T.4    Druilhe, P.5
  • 25
    • 0029098383 scopus 로고
    • Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages
    • Bouharoun-Tayoun H., Oeuvray C., Lunel F., Druilhe P. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J. Exp. Med. 1995, 182(2):409-418.
    • (1995) J. Exp. Med. , vol.182 , Issue.2 , pp. 409-418
    • Bouharoun-Tayoun, H.1    Oeuvray, C.2    Lunel, F.3    Druilhe, P.4
  • 26
    • 24044551679 scopus 로고    scopus 로고
    • Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community
    • Branch O., Casapia W.M., Gamboa D.V., Hernandez J.N., Alava F.F., Roncal N., Alvarez E., Perez E.J., Gotuzzo E. Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community. Malar. J. 2005, 4:27.
    • (2005) Malar. J. , vol.4 , pp. 27
    • Branch, O.1    Casapia, W.M.2    Gamboa, D.V.3    Hernandez, J.N.4    Alava, F.F.5    Roncal, N.6    Alvarez, E.7    Perez, E.J.8    Gotuzzo, E.9
  • 27
    • 0034674698 scopus 로고    scopus 로고
    • Protein synthesis by solid-phase chemical ligation using a safety catch linker
    • Brik A., Keinan E., Dawson P.E. Protein synthesis by solid-phase chemical ligation using a safety catch linker. J. Org. Chem. 2000, 65(12):3829-3835.
    • (2000) J. Org. Chem. , vol.65 , Issue.12 , pp. 3829-3835
    • Brik, A.1    Keinan, E.2    Dawson, P.E.3
  • 28
    • 0023373135 scopus 로고
    • Theoretically determined three-dimensional structure for the repeating tetrapeptide unit of the circumsporozoite coat protein of the malaria parasite Plasmodium falciparum
    • Brooks B.R., Pastor R.W., Carson F.W. Theoretically determined three-dimensional structure for the repeating tetrapeptide unit of the circumsporozoite coat protein of the malaria parasite Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 1987, 84(13):4470-4474.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , Issue.13 , pp. 4470-4474
    • Brooks, B.R.1    Pastor, R.W.2    Carson, F.W.3
  • 29
    • 0033847827 scopus 로고    scopus 로고
    • Genetic diversity and dynamics of Plasmodium falciparum and P. vivax populations in multiply infected children with asymptomatic malaria infections in Papua New Guinea
    • Bruce M.C., Galinski M.R., Barnwell J.W., Donnelly C.A., Walmsley M., Alpers M.P., Walliker D., Day K.P. Genetic diversity and dynamics of Plasmodium falciparum and P. vivax populations in multiply infected children with asymptomatic malaria infections in Papua New Guinea. Parasitology 2000, 121(Pt 3):257-272.
    • (2000) Parasitology , vol.121 , Issue.PART 3 , pp. 257-272
    • Bruce, M.C.1    Galinski, M.R.2    Barnwell, J.W.3    Donnelly, C.A.4    Walmsley, M.5    Alpers, M.P.6    Walliker, D.7    Day, K.P.8
  • 30
    • 27744475030 scopus 로고    scopus 로고
    • Dissection of merozoite surface protein 3, a representative of a family of Plasmodium falciparum surface proteins, reveals an oligomeric and highly elongated molecule
    • Burgess B.R., Schuck P., Garboczi D.N. Dissection of merozoite surface protein 3, a representative of a family of Plasmodium falciparum surface proteins, reveals an oligomeric and highly elongated molecule. J. Biol. Chem. 2005, 280(44):37236-37245.
    • (2005) J. Biol. Chem. , vol.280 , Issue.44 , pp. 37236-37245
    • Burgess, B.R.1    Schuck, P.2    Garboczi, D.N.3
  • 31
    • 0033615313 scopus 로고    scopus 로고
    • Chemical protein synthesis by solid phase ligation of unprotected peptide segments
    • Canne L.E., Botti P., Simon R.J., Chen Y.J., Dennis E.A., Kent S.B.H. Chemical protein synthesis by solid phase ligation of unprotected peptide segments. J. Am. Chem. Soc. 1999, 121(38):8720-8727.
    • (1999) J. Am. Chem. Soc. , vol.121 , Issue.38 , pp. 8720-8727
    • Canne, L.E.1    Botti, P.2    Simon, R.J.3    Chen, Y.J.4    Dennis, E.A.5    Kent, S.B.H.6
  • 32
    • 0001119934 scopus 로고
    • Oxidative reactions of hydrazines.4. Elimination of nitrogen from 1,1-disubstituted-2-arenesulfonhydrazides
    • Carpino L.A. Oxidative reactions of hydrazines.4. Elimination of nitrogen from 1,1-disubstituted-2-arenesulfonhydrazides. J. Am. Chem. Soc. 1957, 79(16):4427-4431.
    • (1957) J. Am. Chem. Soc. , vol.79 , Issue.16 , pp. 4427-4431
    • Carpino, L.A.1
  • 33
    • 0017296791 scopus 로고
    • Malaria transmission blocked by immunisation with gametes of the malaria parasite
    • Carter R., Chen D.H. Malaria transmission blocked by immunisation with gametes of the malaria parasite. Nature 1976, 263(5572):57-60.
    • (1976) Nature , vol.263 , Issue.5572 , pp. 57-60
    • Carter, R.1    Chen, D.H.2
  • 34
    • 0026956560 scopus 로고
    • Transmission immunity in malaria: Reflections on the underlying immune mechanisms during natural infections and following artificial immunization
    • Carter R., Mendis K. Transmission immunity in malaria: Reflections on the underlying immune mechanisms during natural infections and following artificial immunization. Mem. Inst. Oswaldo Cruz 1992, 87(Suppl. 3):169-173.
    • (1992) Mem. Inst. Oswaldo Cruz , vol.87 , Issue.SUPPL. 3 , pp. 169-173
    • Carter, R.1    Mendis, K.2
  • 35
    • 79960668000 scopus 로고    scopus 로고
    • Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: Randomized phase 1b trial in semi-immune adults & children
    • Cech P.G., Aebi T., Abdallah M.S., Mpina M., Machunda E.B., Westerfeld N., Stoffel S.A., Zurbriggen R., Pluschke G., Tanner M., et al. Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: Randomized phase 1b trial in semi-immune adults & children. PLoS One 2011, 6(7):e22273.
    • (2011) PLoS One , vol.6 , Issue.7
    • Cech, P.G.1    Aebi, T.2    Abdallah, M.S.3    Mpina, M.4    Machunda, E.B.5    Westerfeld, N.6    Stoffel, S.A.7    Zurbriggen, R.8    Pluschke, G.9    Tanner, M.10
  • 36
    • 0026795458 scopus 로고
    • The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites
    • Cerami C., Frevert U., Sinnis P., Takacs B., Clavijo P., Santos M.J., Nussenzweig V. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites. Cell 1992, 70(6):1021-1033.
    • (1992) Cell , vol.70 , Issue.6 , pp. 1021-1033
    • Cerami, C.1    Frevert, U.2    Sinnis, P.3    Takacs, B.4    Clavijo, P.5    Santos, M.J.6    Nussenzweig, V.7
  • 37
    • 0024377414 scopus 로고
    • Development of sporozoite vaccines for malaria
    • Chulay J.D. Development of sporozoite vaccines for malaria. Trans. R. Soc. Trop. Med. Hyg. 1989, 83(Suppl.):61-66.
    • (1989) Trans. R. Soc. Trop. Med. Hyg. , vol.83 , Issue.SUPPL. , pp. 61-66
    • Chulay, J.D.1
  • 38
    • 0015736375 scopus 로고
    • Specificity of protection of man immunized against sporozoite-induced falciparum malaria
    • Clyde D.F., McCarthy V.C., Miller R.M., Hornick R.B. Specificity of protection of man immunized against sporozoite-induced falciparum malaria. Am. J. Med. Sci. 1973, 266(6):398-403.
    • (1973) Am. J. Med. Sci. , vol.266 , Issue.6 , pp. 398-403
    • Clyde, D.F.1    McCarthy, V.C.2    Miller, R.M.3    Hornick, R.B.4
  • 39
    • 79959262927 scopus 로고    scopus 로고
    • The vaccine formulation laboratory: A platform for access to adjuvants
    • Collin N., Dubois P.M. The vaccine formulation laboratory: A platform for access to adjuvants. Vaccine 2011, 29(Suppl. 1):A37-A39.
    • (2011) Vaccine , vol.29 , Issue.SUPPL. 1
    • Collin, N.1    Dubois, P.M.2
  • 40
    • 3042667881 scopus 로고    scopus 로고
    • A retrospective examination of reinfection of humans with Plasmodium vivax
    • Collins W.E., Jeffery G.M., Roberts J.M. A retrospective examination of reinfection of humans with Plasmodium vivax. Am. J. Trop. Med. Hyg. 2004, 70(6):642-644.
    • (2004) Am. J. Trop. Med. Hyg. , vol.70 , Issue.6 , pp. 642-644
    • Collins, W.E.1    Jeffery, G.M.2    Roberts, J.M.3
  • 41
    • 12344299732 scopus 로고    scopus 로고
    • The plasmodium circumsporozoite protein is proteolytically processed during cell invasion
    • Coppi A., Pinzon-Ortiz C., Hutter C., Sinnis P. The plasmodium circumsporozoite protein is proteolytically processed during cell invasion. J. Exp. Med. 2005, 201(1):27-33.
    • (2005) J. Exp. Med. , vol.201 , Issue.1 , pp. 27-33
    • Coppi, A.1    Pinzon-Ortiz, C.2    Hutter, C.3    Sinnis, P.4
  • 42
    • 79951707136 scopus 로고    scopus 로고
    • The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
    • Coppi A., Natarajan R., Pradel G., Bennett B.L., James E.R., Roggero M.A., Corradin G., Persson C., Tewari R., Sinnis P. The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. J. Exp. Med. 2011, 208(2):341-356.
    • (2011) J. Exp. Med. , vol.208 , Issue.2 , pp. 341-356
    • Coppi, A.1    Natarajan, R.2    Pradel, G.3    Bennett, B.L.4    James, E.R.5    Roggero, M.A.6    Corradin, G.7    Persson, C.8    Tewari, R.9    Sinnis, P.10
  • 43
    • 34247475236 scopus 로고    scopus 로고
    • Peptide based malaria vaccine development: Personal considerations
    • Corradin G. Peptide based malaria vaccine development: Personal considerations. Microbes Infect. 2007, 9(6):767-771.
    • (2007) Microbes Infect. , vol.9 , Issue.6 , pp. 767-771
    • Corradin, G.1
  • 44
    • 5644266187 scopus 로고    scopus 로고
    • Medicinal application of long synthetic peptide technology
    • Corradin G., Spertini F., Verdini A. Medicinal application of long synthetic peptide technology. Expert Opin. Biol. Ther. 2004, 4(10):1629-1639.
    • (2004) Expert Opin. Biol. Ther. , vol.4 , Issue.10 , pp. 1629-1639
    • Corradin, G.1    Spertini, F.2    Verdini, A.3
  • 45
    • 37549060585 scopus 로고    scopus 로고
    • Protein structure based strategies for antigen discovery and vaccine development against malaria and other pathogens
    • Corradin G., Villard V., Kajava A.V. Protein structure based strategies for antigen discovery and vaccine development against malaria and other pathogens. Endocr. Metab. Immune Disord. Drug Targets 2007, 7(4):259-265.
    • (2007) Endocr. Metab. Immune Disord. Drug Targets , vol.7 , Issue.4 , pp. 259-265
    • Corradin, G.1    Villard, V.2    Kajava, A.V.3
  • 46
    • 77958048566 scopus 로고    scopus 로고
    • Long synthetic peptides for the production of vaccines and drugs: A technological platform coming of age
    • Corradin G., Kajava A.V., Verdini A. Long synthetic peptides for the production of vaccines and drugs: A technological platform coming of age. Sci. Transl. Med. 2010, 2(50):50rv3.
    • (2010) Sci. Transl. Med. , vol.2 , Issue.50
    • Corradin, G.1    Kajava, A.V.2    Verdini, A.3
  • 47
    • 14744281606 scopus 로고
    • Ueber einige neue hippursäureanalog constituierte synthetisch dargestellte aminosauren
    • Curtius T. Ueber einige neue hippursäureanalog constituierte synthetisch dargestellte aminosauren. J. Prakt. Chemie 1882, 26:145-208.
    • (1882) J. Prakt. Chemie , vol.26 , pp. 145-208
    • Curtius, T.1
  • 48
    • 84980898395 scopus 로고
    • Synthetische versuche mit hippurazid
    • Curtius T. Synthetische versuche mit hippurazid. Ber. Dtsch. Chem. Ges. 1902, 35:3226-3233.
    • (1902) Ber. Dtsch. Chem. Ges. , vol.35 , pp. 3226-3233
    • Curtius, T.1
  • 51
    • 4644338525 scopus 로고
    • Studies on total synthesis of an enzyme. I. Objective and strategy
    • Denkewalter R.G., Veber D.F., Holly F.W., Hirschmann R. Studies on total synthesis of an enzyme. I. Objective and strategy. J. Am. Chem. Soc. 1969, 91(2):502-503.
    • (1969) J. Am. Chem. Soc. , vol.91 , Issue.2 , pp. 502-503
    • Denkewalter, R.G.1    Veber, D.F.2    Holly, F.W.3    Hirschmann, R.4
  • 53
    • 59649108316 scopus 로고    scopus 로고
    • Acquired immunity to malaria
    • (Table of Contents)
    • Doolan D.L., Dobano C., Baird J.K. Acquired immunity to malaria. Clin. Microbiol. Rev. 2009, 22(1):13-36. (Table of Contents).
    • (2009) Clin. Microbiol. Rev. , vol.22 , Issue.1 , pp. 13-36
    • Doolan, D.L.1    Dobano, C.2    Baird, J.K.3
  • 57
    • 0009619530 scopus 로고
    • Resynthesis of insulin from its glycyl and phenylalanyl chains
    • Du Y.C., Zhang Y.S., Lu Z.X., Tsou C.L. Resynthesis of insulin from its glycyl and phenylalanyl chains. Sci. Sin. 1961, 10(1):84-104.
    • (1961) Sci. Sin. , vol.10 , Issue.1 , pp. 84-104
    • Du, Y.C.1    Zhang, Y.S.2    Lu, Z.X.3    Tsou, C.L.4
  • 58
    • 0021160478 scopus 로고
    • DNA cloning of Plasmodium falciparum circumsporozoite gene: Amino acid sequence of repetitive epitope
    • Enea V., Ellis J., Zavala F., Arnot D.E., Asavanich A., Masuda A., Quakyi I., Nussenzweig R.S. DNA cloning of Plasmodium falciparum circumsporozoite gene: Amino acid sequence of repetitive epitope. Science 1984, 225(4662):628-630.
    • (1984) Science , vol.225 , Issue.4662 , pp. 628-630
    • Enea, V.1    Ellis, J.2    Zavala, F.3    Arnot, D.E.4    Asavanich, A.5    Masuda, A.6    Quakyi, I.7    Nussenzweig, R.S.8
  • 59
    • 0032008130 scopus 로고    scopus 로고
    • Malaria vaccine development: Current status
    • Engers H.D., Godal T. Malaria vaccine development: Current status. Parasitol. Today 1998, 14(2):56-64.
    • (1998) Parasitol. Today , vol.14 , Issue.2 , pp. 56-64
    • Engers, H.D.1    Godal, T.2
  • 61
    • 0344351815 scopus 로고    scopus 로고
    • Semisynthesis of cytotoxic proteins using a modified protein splicing element
    • Evans T.C., Benner J., Xu M.Q. Semisynthesis of cytotoxic proteins using a modified protein splicing element. Protein Sci. 1998, 7(11):2256-2264.
    • (1998) Protein Sci. , vol.7 , Issue.11 , pp. 2256-2264
    • Evans, T.C.1    Benner, J.2    Xu, M.Q.3
  • 62
    • 0030879397 scopus 로고    scopus 로고
    • Clinical trials of malaria vaccines: Progress and prospects
    • Facer C.A., Tanner M. Clinical trials of malaria vaccines: Progress and prospects. Adv. Parasitol. 1997, 39:1-68.
    • (1997) Adv. Parasitol. , vol.39 , pp. 1-68
    • Facer, C.A.1    Tanner, M.2
  • 64
    • 84981756125 scopus 로고
    • Synthese von derivaten der Polypeptid
    • Fischer E. Synthese von derivaten der Polypeptid. Ber. Dtsch. Chem. Ges. 1903, 36:2094-2106.
    • (1903) Ber. Dtsch. Chem. Ges. , vol.36 , pp. 2094-2106
    • Fischer, E.1
  • 65
    • 84946388015 scopus 로고
    • Synthese von polypeptiden. XVII
    • Fischer E. Synthese von polypeptiden. XVII. Ber. Dtsch. Chem. Ges. 1907, 40:1754-1767.
    • (1907) Ber. Dtsch. Chem. Ges. , vol.40 , pp. 1754-1767
    • Fischer, E.1
  • 66
    • 84945084007 scopus 로고
    • Ueber einige derivate des glykokolls
    • Fischer E., Fourneau E. Ueber einige derivate des glykokolls. Ber.Dtsch. Chem. Ges. 1901, 34:2868-2879.
    • (1901) Ber.Dtsch. Chem. Ges. , vol.34 , pp. 2868-2879
    • Fischer, E.1    Fourneau, E.2
  • 67
    • 0031255317 scopus 로고    scopus 로고
    • Induction of protective CTL responses against the Plasmodium yoelii circumsporozoite protein by immunization with peptides
    • Franke E.D., Corradin G., Hoffman S.L. Induction of protective CTL responses against the Plasmodium yoelii circumsporozoite protein by immunization with peptides. J. Immunol. 1997, 159(7):3424-3433.
    • (1997) J. Immunol. , vol.159 , Issue.7 , pp. 3424-3433
    • Franke, E.D.1    Corradin, G.2    Hoffman, S.L.3
  • 68
    • 0027457377 scopus 로고
    • Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes
    • Frevert U., Sinnis P., Cerami C., Shreffler W., Takacs B., Nussenzweig V. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. J. Exp. Med. 1993, 177(5):1287-1298.
    • (1993) J. Exp. Med. , vol.177 , Issue.5 , pp. 1287-1298
    • Frevert, U.1    Sinnis, P.2    Cerami, C.3    Shreffler, W.4    Takacs, B.5    Nussenzweig, V.6
  • 71
    • 77956399020 scopus 로고    scopus 로고
    • Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum
    • Genton B., D'Acremont V., Lurati-Ruiz F., Verhage D., Audran R., Hermsen C., Wolters L., Reymond C., Spertini F., Sauerwein R. Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum. Vaccine 2010, 28(40):6573-6580.
    • (2010) Vaccine , vol.28 , Issue.40 , pp. 6573-6580
    • Genton, B.1    D'Acremont, V.2    Lurati-Ruiz, F.3    Verhage, D.4    Audran, R.5    Hermsen, C.6    Wolters, L.7    Reymond, C.8    Spertini, F.9    Sauerwein, R.10
  • 72
    • 0025174231 scopus 로고
    • Identification of a T-cell epitope on the circumsporozoite protein of Plasmodium vivax
    • George F.W., Law J.L., Rich K.A., Martin W.J. Identification of a T-cell epitope on the circumsporozoite protein of Plasmodium vivax. Infect. Immun. 1990, 58(2):575-578.
    • (1990) Infect. Immun. , vol.58 , Issue.2 , pp. 575-578
    • George, F.W.1    Law, J.L.2    Rich, K.A.3    Martin, W.J.4
  • 73
    • 0027021116 scopus 로고
    • Correlation between destruction of malarial parasites by polymorphonuclear leukocytes and oxidative stress
    • Golenser J., Kamyl M., Tsafack A., Marva E., Cohen A., Kitrossky N., Chevion M. Correlation between destruction of malarial parasites by polymorphonuclear leukocytes and oxidative stress. Free Radic. Res. Commun. 1992, 17(4):249-262.
    • (1992) Free Radic. Res. Commun. , vol.17 , Issue.4 , pp. 249-262
    • Golenser, J.1    Kamyl, M.2    Tsafack, A.3    Marva, E.4    Cohen, A.5    Kitrossky, N.6    Chevion, M.7
  • 74
    • 62249099133 scopus 로고    scopus 로고
    • The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer
    • Gondeau C., Corradin G., Heitz F., Le Peuch C., Balbo A., Schuck P., Kajava A.V. The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer. Mol. Biochem. Parasitol. 2009, 165(2):153-161.
    • (2009) Mol. Biochem. Parasitol. , vol.165 , Issue.2 , pp. 153-161
    • Gondeau, C.1    Corradin, G.2    Heitz, F.3    Le Peuch, C.4    Balbo, A.5    Schuck, P.6    Kajava, A.V.7
  • 76
    • 0035403376 scopus 로고    scopus 로고
    • Variants of the Plasmodium vivax circumsporozoite protein (VK210 and VK247) in Colombian isolates
    • Gonzalez J.M., Hurtado S., Arevalo-Herrera M., Herrera S. Variants of the Plasmodium vivax circumsporozoite protein (VK210 and VK247) in Colombian isolates. Mem. Inst. Oswaldo Cruz 2001, 96(5):709-712.
    • (2001) Mem. Inst. Oswaldo Cruz , vol.96 , Issue.5 , pp. 709-712
    • Gonzalez, J.M.1    Hurtado, S.2    Arevalo-Herrera, M.3    Herrera, S.4
  • 77
    • 77958482582 scopus 로고    scopus 로고
    • Malaria vaccine design: Immunological considerations
    • Good M.F., Doolan D.L. Malaria vaccine design: Immunological considerations. Immunity 2010, 33(4):555-566.
    • (2010) Immunity , vol.33 , Issue.4 , pp. 555-566
    • Good, M.F.1    Doolan, D.L.2
  • 78
    • 0024155455 scopus 로고
    • The T cell response to the malaria circumsporozoite protein: An immunological approach to vaccine development
    • Good M.F., Berzofsky J.A., Miller L.H. The T cell response to the malaria circumsporozoite protein: An immunological approach to vaccine development. Annu. Rev. Immunol. 1988, 6:663-688.
    • (1988) Annu. Rev. Immunol. , vol.6 , pp. 663-688
    • Good, M.F.1    Berzofsky, J.A.2    Miller, L.H.3
  • 79
    • 84858757635 scopus 로고
    • Sur des colloides azotes
    • Grimaux E. Sur des colloides azotes. Bull. Soc. Chim. 1882, 38:64.
    • (1882) Bull. Soc. Chim. , vol.38 , pp. 64
    • Grimaux, E.1
  • 80
    • 0014675276 scopus 로고
    • Total synthesis of an enzyme with ribonuclease a activity
    • Gutte B., Merrifield R.B. Total synthesis of an enzyme with ribonuclease a activity. J. Am. Chem. Soc. 1969, 91(2):501-502.
    • (1969) J. Am. Chem. Soc. , vol.91 , Issue.2 , pp. 501-502
    • Gutte, B.1    Merrifield, R.B.2
  • 81
    • 0034687752 scopus 로고    scopus 로고
    • Chemical synthesis and spontaneous folding of a multidomain protein: Anticoagulant microprotein S
    • Hackeng T.M., Fernandez J.A., Dawson P.E., Kent S.B., Griffin J.H. Chemical synthesis and spontaneous folding of a multidomain protein: Anticoagulant microprotein S. Proc. Natl. Acad. Sci. USA 2000, 97(26):14074-14078.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.26 , pp. 14074-14078
    • Hackeng, T.M.1    Fernandez, J.A.2    Dawson, P.E.3    Kent, S.B.4    Griffin, J.H.5
  • 82
    • 0027756896 scopus 로고
    • A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants
    • Harbury P.B., Zhang T., Kim P.S., Alber T. A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science 1993, 262(5138):1401-1407.
    • (1993) Science , vol.262 , Issue.5138 , pp. 1401-1407
    • Harbury, P.B.1    Zhang, T.2    Kim, P.S.3    Alber, T.4
  • 84
    • 33947107414 scopus 로고    scopus 로고
    • Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial
    • Hermsen C.C., Verhage D.F., Telgt D.S., Teelen K., Bousema J.T., Roestenberg M., Bolad A., Berzins K., Corradin G., Leroy O., et al. Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial. Vaccine 2007, 25(15):2930-2940.
    • (2007) Vaccine , vol.25 , Issue.15 , pp. 2930-2940
    • Hermsen, C.C.1    Verhage, D.F.2    Telgt, D.S.3    Teelen, K.4    Bousema, J.T.5    Roestenberg, M.6    Bolad, A.7    Berzins, K.8    Corradin, G.9    Leroy, O.10
  • 85
    • 84858757636 scopus 로고    scopus 로고
    • Bentham Science Publishers Ltd., CA, (Chapter 4), S. Herrera, M. Arevalo-Herrera (Eds.)
    • Immune Responses to Parasitic Infections 2010, Bentham Science Publishers Ltd., CA, (Chapter 4). S. Herrera, M. Arevalo-Herrera (Eds.).
    • (2010) Immune Responses to Parasitic Infections
  • 86
    • 0026735577 scopus 로고
    • Human recognition of T cell epitopes on the Plasmodium vivax circumsporozoite protein
    • Herrera S., Escobar P., de Plata C., Avila G.I., Corradin G., Herrera M.A. Human recognition of T cell epitopes on the Plasmodium vivax circumsporozoite protein. J. Immunol. 1992, 148(12):3986-3990.
    • (1992) J. Immunol. , vol.148 , Issue.12 , pp. 3986-3990
    • Herrera, S.1    Escobar, P.2    de Plata, C.3    Avila, G.I.4    Corradin, G.5    Herrera, M.A.6
  • 87
    • 0026482754 scopus 로고
    • Failure of a synthetic vaccine to protect Aotus lemurinus against asexual blood stages of Plasmodium falciparum
    • Herrera S., Herrera M.A., Corredor A., Rosero F., Clavijo C., Guerrero R. Failure of a synthetic vaccine to protect Aotus lemurinus against asexual blood stages of Plasmodium falciparum. Am. J. Trop. Med. Hyg. 1992, 47(5):682-690.
    • (1992) Am. J. Trop. Med. Hyg. , vol.47 , Issue.5 , pp. 682-690
    • Herrera, S.1    Herrera, M.A.2    Corredor, A.3    Rosero, F.4    Clavijo, C.5    Guerrero, R.6
  • 88
  • 90
    • 28044446138 scopus 로고    scopus 로고
    • Safety and elicitation of humoral and cellular responses in colombian malaria-naive volunteers by a Plasmodium vivax circumsporozoite protein-derived synthetic vaccine
    • Herrera S., Bonelo A., Perlaza B.L., Fernandez O.L., Victoria L., Lenis A.M., Soto L., Hurtado H., Acuna L.M., Velez J.D., et al. Safety and elicitation of humoral and cellular responses in colombian malaria-naive volunteers by a Plasmodium vivax circumsporozoite protein-derived synthetic vaccine. Am. J. Trop. Med. Hyg. 2005, 73(5 Suppl.):3-9.
    • (2005) Am. J. Trop. Med. Hyg. , vol.73 , Issue.5 SUPPL. , pp. 3-9
    • Herrera, S.1    Bonelo, A.2    Perlaza, B.L.3    Fernandez, O.L.4    Victoria, L.5    Lenis, A.M.6    Soto, L.7    Hurtado, H.8    Acuna, L.M.9    Velez, J.D.10
  • 91
    • 34249887696 scopus 로고    scopus 로고
    • Plasmodium vivax thrombospondin related adhesion protein: Immunogenicity and protective efficacy in rodents and Aotus monkeys
    • Herrera S., Castellanos A., Arevalo-Herrera M., Restrepo N., Gulloso L., Corradin G. Plasmodium vivax thrombospondin related adhesion protein: Immunogenicity and protective efficacy in rodents and Aotus monkeys. Mem. Inst. Oswaldo Cruz 2007, 102(3):411-416.
    • (2007) Mem. Inst. Oswaldo Cruz , vol.102 , Issue.3 , pp. 411-416
    • Herrera, S.1    Castellanos, A.2    Arevalo-Herrera, M.3    Restrepo, N.4    Gulloso, L.5    Corradin, G.6
  • 93
    • 79952468617 scopus 로고    scopus 로고
    • Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51
    • Herrera S., Fernandez O.L., Vera O., Cardenas W., Ramirez O., Palacios R., Chen-Mok M., Corradin G., Arevalo-Herrera M. Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51. Am. J. Trop. Med. Hyg. 2011, 84(2 Suppl.):12-20.
    • (2011) Am. J. Trop. Med. Hyg. , vol.84 , Issue.2 SUPPL. , pp. 12-20
    • Herrera, S.1    Fernandez, O.L.2    Vera, O.3    Cardenas, W.4    Ramirez, O.5    Palacios, R.6    Chen-Mok, M.7    Corradin, G.8    Arevalo-Herrera, M.9
  • 98
    • 0021368476 scopus 로고
    • Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies
    • Hollingdale M.R., Nardin E.H., Tharavanij S., Schwartz A.L., Nussenzweig R.S. Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies. J. Immunol. 1984, 132(2):909-913.
    • (1984) J. Immunol. , vol.132 , Issue.2 , pp. 909-913
    • Hollingdale, M.R.1    Nardin, E.H.2    Tharavanij, S.3    Schwartz, A.L.4    Nussenzweig, R.S.5
  • 100
    • 0027351974 scopus 로고
    • Antibodies to the circumsporozoite protein and protective immunity to malaria sporozoites
    • Jones T.R., Ballou W.R., Hoffman S.L. Antibodies to the circumsporozoite protein and protective immunity to malaria sporozoites. Prog. Clin. Parasitol. 1993, 3:103-117.
    • (1993) Prog. Clin. Parasitol. , vol.3 , pp. 103-117
    • Jones, T.R.1    Ballou, W.R.2    Hoffman, S.L.3
  • 101
    • 0035783062 scopus 로고    scopus 로고
    • Review: Proteins with repeated sequence-Structural prediction and modeling
    • Kajava A.V. Review: Proteins with repeated sequence-Structural prediction and modeling. J. Struct. Biol. 2001, 134(2-3):132-144.
    • (2001) J. Struct. Biol. , vol.134 , Issue.2-3 , pp. 132-144
    • Kajava, A.V.1
  • 102
    • 0006788673 scopus 로고
    • New aspects of solid phase peptide synthesis
    • Academic Press, San Diego, E.P. Goldberg, A. Nakajima (Eds.)
    • Kent S.B.H. New aspects of solid phase peptide synthesis. Biomedical Polymers 1980, Academic Press, San Diego. E.P. Goldberg, A. Nakajima (Eds.).
    • (1980) Biomedical Polymers
    • Kent, S.B.H.1
  • 103
    • 62449282062 scopus 로고    scopus 로고
    • Total chemical synthesis of proteins
    • Kent S.B. Total chemical synthesis of proteins. Chem. Soc. Rev. 2009, 38(2):338-351.
    • (2009) Chem. Soc. Rev. , vol.38 , Issue.2 , pp. 338-351
    • Kent, S.B.1
  • 104
    • 0023610352 scopus 로고
    • Generation of reactive oxygen radicals by human phagocytic cells activated by Plasmodium falciparum
    • Kharazmi A., Jepsen S., Andersen B.J. Generation of reactive oxygen radicals by human phagocytic cells activated by Plasmodium falciparum. Scand. J. Immunol. 1987, 25(4):335-341.
    • (1987) Scand. J. Immunol. , vol.25 , Issue.4 , pp. 335-341
    • Kharazmi, A.1    Jepsen, S.2    Andersen, B.J.3
  • 106
    • 73449092497 scopus 로고    scopus 로고
    • Acute attack of AIP (acute intermittent porphyria) with severe vivax malaria associated with convulsions: A case report
    • Kochar S.K., Mahajan M., Gupta R.P., Middha S., Acharya J., Kochar A., Das A., Kochar D.K. Acute attack of AIP (acute intermittent porphyria) with severe vivax malaria associated with convulsions: A case report. J. Vector Borne Dis. 2009, 46(4):307-309.
    • (2009) J. Vector Borne Dis. , vol.46 , Issue.4 , pp. 307-309
    • Kochar, S.K.1    Mahajan, M.2    Gupta, R.P.3    Middha, S.4    Acharya, J.5    Kochar, A.6    Das, A.7    Kochar, D.K.8
  • 108
    • 0013811635 scopus 로고
    • Malaria Vaccine Development: 20 years of hopes, hypes and limited achievements. Total synthesis of crystalline bovine insulin
    • Kung Y.T., Du Y.C., Huang W.T., Chen C.C., Ke L.T., Hu S.C., Jiang R.Q., Chu S.Q., Niu C.I., Hsu J.Z., et al. Malaria Vaccine Development: 20 years of hopes, hypes and limited achievements. Total synthesis of crystalline bovine insulin. Sci. Sin. 1965, 14(11):1710-1716.
    • (1965) Sci. Sin. , vol.14 , Issue.11 , pp. 1710-1716
    • Kung, Y.T.1    Du, Y.C.2    Huang, W.T.3    Chen, C.C.4    Ke, L.T.5    Hu, S.C.6    Jiang, R.Q.7    Chu, S.Q.8    Niu, C.I.9    Hsu, J.Z.10
  • 109
    • 0034938975 scopus 로고    scopus 로고
    • A synthetic malaria vaccine elicits a potent CD8(+) and CD4(+) T lymphocyte immune response in humans. Implications for vaccination strategies
    • Lopez J.A., Weilenman C., Audran R., Roggero M.A., Bonelo A., Tiercy J.M., Spertini F., Corradin G. A synthetic malaria vaccine elicits a potent CD8(+) and CD4(+) T lymphocyte immune response in humans. Implications for vaccination strategies. Eur. J. Immunol. 2001, 31(7):1989-1998.
    • (2001) Eur. J. Immunol. , vol.31 , Issue.7 , pp. 1989-1998
    • Lopez, J.A.1    Weilenman, C.2    Audran, R.3    Roggero, M.A.4    Bonelo, A.5    Tiercy, J.M.6    Spertini, F.7    Corradin, G.8
  • 111
    • 0024327430 scopus 로고
    • Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes
    • Lyon J.A., Thomas A.W., Hall T., Chulay J.D. Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes. Mol. Biochem. Parasitol. 1989, 36(1):77-85.
    • (1989) Mol. Biochem. Parasitol. , vol.36 , Issue.1 , pp. 77-85
    • Lyon, J.A.1    Thomas, A.W.2    Hall, T.3    Chulay, J.D.4
  • 112
    • 0024349561 scopus 로고
    • Antibodies to blood stage antigens of Plasmodium-falciparum in rural gambians and their relation to protection against infection
    • Marsh K., Otoo L., Hayes R.J., Carson D.C., Greenwood B.M. Antibodies to blood stage antigens of Plasmodium-falciparum in rural gambians and their relation to protection against infection. Trans. R. Soc. Trop. Med. Hyg. 1989, 83(3):293-303.
    • (1989) Trans. R. Soc. Trop. Med. Hyg. , vol.83 , Issue.3 , pp. 293-303
    • Marsh, K.1    Otoo, L.2    Hayes, R.J.3    Carson, D.C.4    Greenwood, B.M.5
  • 113
    • 0026556752 scopus 로고
    • Two novel alleles within subfamilies of the merozoite surface antigen 2 (MSA-2) of Plasmodium falciparum
    • Marshall V.M., Coppel R.L., Anders R.F., Kemp D.J. Two novel alleles within subfamilies of the merozoite surface antigen 2 (MSA-2) of Plasmodium falciparum. Mol. Biochem. Parasitol. 1992, 50(1):181-184.
    • (1992) Mol. Biochem. Parasitol. , vol.50 , Issue.1 , pp. 181-184
    • Marshall, V.M.1    Coppel, R.L.2    Anders, R.F.3    Kemp, D.J.4
  • 114
    • 0031467009 scopus 로고    scopus 로고
    • Conservation of structural motifs and antigenic diversity in the Plasmodium falciparum merozoite surface protein-3 (MSP-3)
    • McColl D.J., Anders R.F. Conservation of structural motifs and antigenic diversity in the Plasmodium falciparum merozoite surface protein-3 (MSP-3). Mol. Biochem. Parasitol. 1997, 90(1):21-31.
    • (1997) Mol. Biochem. Parasitol. , vol.90 , Issue.1 , pp. 21-31
    • McColl, D.J.1    Anders, R.F.2
  • 116
    • 0000508898 scopus 로고
    • The passive transfer of human malarial immunity
    • McGregor I.A. The passive transfer of human malarial immunity. Am. J. Trop. Med. Hyg. 1964, 13(Suppl.):237-239.
    • (1964) Am. J. Trop. Med. Hyg. , vol.13 , Issue.SUPPL. , pp. 237-239
    • McGregor, I.A.1
  • 117
    • 0014431831 scopus 로고
    • Soluble antigens in the blood of African patients with severe Plasmodium falciparum malaria
    • McGregor I.A., Turner M.W., Williams K., Hall P. Soluble antigens in the blood of African patients with severe Plasmodium falciparum malaria. Lancet 1968, 1(7548):881-884.
    • (1968) Lancet , vol.1 , Issue.7548 , pp. 881-884
    • McGregor, I.A.1    Turner, M.W.2    Williams, K.3    Hall, P.4
  • 118
    • 0001347236 scopus 로고
    • New amine-masking groups for peptide synthesis
    • Mckay F.C., Albertson N.F. New amine-masking groups for peptide synthesis. J. Am. Chem. Soc. 1957, 79(17):4686-4690.
    • (1957) J. Am. Chem. Soc. , vol.79 , Issue.17 , pp. 4686-4690
    • Mckay, F.C.1    Albertson, N.F.2
  • 119
    • 0023108995 scopus 로고
    • Malaria transmission-blocking immunity induced by natural infections of Plasmodium vivax in humans
    • Mendis K.N., Munesinghe Y.D., de Silva Y.N., Keragalla I., Carter R. Malaria transmission-blocking immunity induced by natural infections of Plasmodium vivax in humans. Infect. Immun. 1987, 55(2):369-372.
    • (1987) Infect. Immun. , vol.55 , Issue.2 , pp. 369-372
    • Mendis, K.N.1    Munesinghe, Y.D.2    de Silva, Y.N.3    Keragalla, I.4    Carter, R.5
  • 121
    • 0001657112 scopus 로고
    • Peptide synthesis on a solid polymer
    • Merrifield R.B. Peptide synthesis on a solid polymer. Fed. Proc. 1962, 21(2):412.
    • (1962) Fed. Proc. , vol.21 , Issue.2 , pp. 412
    • Merrifield, R.B.1
  • 122
    • 20744456789 scopus 로고
    • Solid phase peptide synthesis. 1. Synthesis of a tetrapeptide
    • Merrifield R.B. Solid phase peptide synthesis. 1. Synthesis of a tetrapeptide. J. Am. Chem. Soc. 1963, 85(14):2149.
    • (1963) J. Am. Chem. Soc. , vol.85 , Issue.14 , pp. 2149
    • Merrifield, R.B.1
  • 124
    • 0013979922 scopus 로고
    • Instrument for automated synthesis of peptides
    • Merrifield R.B., Stewart J.M., Jernberg N. Instrument for automated synthesis of peptides. Anal. Chem. 1966, 38(13):1905-1914.
    • (1966) Anal. Chem. , vol.38 , Issue.13 , pp. 1905-1914
    • Merrifield, R.B.1    Stewart, J.M.2    Jernberg, N.3
  • 125
    • 0027398768 scopus 로고
    • Malaria vaccine: Immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity
    • Migliorini P., Betschart B., Corradin G. Malaria vaccine: Immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity. Eur. J. Immunol. 1993, 23(2):582-585.
    • (1993) Eur. J. Immunol. , vol.23 , Issue.2 , pp. 582-585
    • Migliorini, P.1    Betschart, B.2    Corradin, G.3
  • 126
    • 0021682395 scopus 로고
    • An improved synthesis of crystalline mammalian glucagon
    • Mojsov S., Merrifield R.B. An improved synthesis of crystalline mammalian glucagon. Eur. J. Biochem. 1984, 145(3):601-605.
    • (1984) Eur. J. Biochem. , vol.145 , Issue.3 , pp. 601-605
    • Mojsov, S.1    Merrifield, R.B.2
  • 127
    • 77956481961 scopus 로고    scopus 로고
    • Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambarene, Gabon
    • Mordmuller B., Szywon K., Greutelaers B., Esen M., Mewono L., Treut C., Murbeth R.E., Chilengi R., Noor R., Kilama W.L., et al. Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambarene, Gabon. Vaccine 2010, 28(41):6698-6703.
    • (2010) Vaccine , vol.28 , Issue.41 , pp. 6698-6703
    • Mordmuller, B.1    Szywon, K.2    Greutelaers, B.3    Esen, M.4    Mewono, L.5    Treut, C.6    Murbeth, R.E.7    Chilengi, R.8    Noor, R.9    Kilama, W.L.10
  • 128
    • 0035814134 scopus 로고    scopus 로고
    • Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design
    • Moreno R., Jiang L., Moehle K., Zurbriggen R., Gluck R., Robinson J.A., Pluschke G. Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design. Chembiochem 2001, 2(11):838-843.
    • (2001) Chembiochem , vol.2 , Issue.11 , pp. 838-843
    • Moreno, R.1    Jiang, L.2    Moehle, K.3    Zurbriggen, R.4    Gluck, R.5    Robinson, J.A.6    Pluschke, G.7
  • 130
    • 0042244460 scopus 로고    scopus 로고
    • Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1
    • Mueller M.S., Renard A., Boato F., Vogel D., Naegeli M., Zurbriggen R., Robinson J.A., Pluschke G. Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1. Infect. Immun. 2003, 71(8):4749-4758.
    • (2003) Infect. Immun. , vol.71 , Issue.8 , pp. 4749-4758
    • Mueller, M.S.1    Renard, A.2    Boato, F.3    Vogel, D.4    Naegeli, M.5    Zurbriggen, R.6    Robinson, J.A.7    Pluschke, G.8
  • 131
    • 0032499752 scopus 로고    scopus 로고
    • Expressed protein ligation: A general method for protein engineering
    • Muir T.W., Sondhi D., Cole P.A. Expressed protein ligation: A general method for protein engineering. Proc. Natl. Acad. Sci. USA 1998, 95(12):6705-6710.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.12 , pp. 6705-6710
    • Muir, T.W.1    Sondhi, D.2    Cole, P.A.3
  • 132
    • 0027326632 scopus 로고
    • Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells suggesting a role for this molecule in sporozoite invasion of hepatocytes
    • Muller H.M., Reckmann I., Hollingdale M.R., Bujard H., Robson K.J., Crisanti A. Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells suggesting a role for this molecule in sporozoite invasion of hepatocytes. EMBO J. 1993, 12(7):2881-2889.
    • (1993) EMBO J. , vol.12 , Issue.7 , pp. 2881-2889
    • Muller, H.M.1    Reckmann, I.2    Hollingdale, M.R.3    Bujard, H.4    Robson, K.J.5    Crisanti, A.6
  • 133
    • 0027638134 scopus 로고
    • Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum in parasite-host cell interactions
    • Muller H.M., Scarselli E., Crisanti A. Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum in parasite-host cell interactions. Parassitologia 1993, 35(Suppl.):69-72.
    • (1993) Parassitologia , vol.35 , Issue.SUPPL. , pp. 69-72
    • Muller, H.M.1    Scarselli, E.2    Crisanti, A.3
  • 134
    • 74949109718 scopus 로고    scopus 로고
    • The past decade in malaria synthetic peptide vaccine clinical trials
    • Nardin E. The past decade in malaria synthetic peptide vaccine clinical trials. Hum. Vaccin. 2010, 6(1):27-38.
    • (2010) Hum. Vaccin. , vol.6 , Issue.1 , pp. 27-38
    • Nardin, E.1
  • 135
    • 0027400796 scopus 로고
    • T cell responses to pre-erythrocytic stages of malaria: Role in protection and vaccine development against pre-erythrocytic stages
    • Nardin E.H., Nussenzweig R.S. T cell responses to pre-erythrocytic stages of malaria: Role in protection and vaccine development against pre-erythrocytic stages. Annu. Rev. Immunol. 1993, 11:687-727.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 687-727
    • Nardin, E.H.1    Nussenzweig, R.S.2
  • 137
    • 0035168781 scopus 로고    scopus 로고
    • A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types
    • Nardin E.H., Calvo-Calle J.M., Oliveira G.A., Nussenzweig R.S., Schneider M., Tiercy J.M., Loutan L., Hochstrasser D., Rose K. A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types. J. Immunol. 2001, 166(1):481-489.
    • (2001) J. Immunol. , vol.166 , Issue.1 , pp. 481-489
    • Nardin, E.H.1    Calvo-Calle, J.M.2    Oliveira, G.A.3    Nussenzweig, R.S.4    Schneider, M.5    Tiercy, J.M.6    Loutan, L.7    Hochstrasser, D.8    Rose, K.9
  • 139
    • 0032505997 scopus 로고    scopus 로고
    • Chemical synthesis of the precursor molecule of the Aequorea green fluorescent protein, subsequent folding, and development of fluorescence
    • Nishiuchi Y., Inui T., Nishio H., Bodi J., Kimura T., Tsuji F.I., Sakakibara S. Chemical synthesis of the precursor molecule of the Aequorea green fluorescent protein, subsequent folding, and development of fluorescence. Proc. Natl. Acad. Sci. USA 1998, 95(23):13549-13554.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.23 , pp. 13549-13554
    • Nishiuchi, Y.1    Inui, T.2    Nishio, H.3    Bodi, J.4    Kimura, T.5    Tsuji, F.I.6    Sakakibara, S.7
  • 140
    • 9544237169 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Shoklo SPf66 Malaria Vaccine Trial Group
    • Nosten F., Luxemburger C., Kyle D.E., Ballou W.R., Wittes J., Wah E., Chongsuphajaisiddhi T., Gordon D.M., White N.J., Sadoff J.C., et al. Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Shoklo SPf66 Malaria Vaccine Trial Group. Lancet 1996, 348(9029):701-707.
    • (1996) Lancet , vol.348 , Issue.9029 , pp. 701-707
    • Nosten, F.1    Luxemburger, C.2    Kyle, D.E.3    Ballou, W.R.4    Wittes, J.5    Wah, E.6    Chongsuphajaisiddhi, T.7    Gordon, D.M.8    White, N.J.9    Sadoff, J.C.10
  • 141
    • 0018964364 scopus 로고
    • Use of radiation-attenuated sporozoites in the immunoprophylaxis of malaria
    • Nussenzweig R. Use of radiation-attenuated sporozoites in the immunoprophylaxis of malaria. Int. J. Nucl. Med. Biol. 1980, 7(2):89-96.
    • (1980) Int. J. Nucl. Med. Biol. , vol.7 , Issue.2 , pp. 89-96
    • Nussenzweig, R.1
  • 143
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei
    • Nussenzweig R.S., Vanderberg J., Most H., Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 1967, 216(5111):160-162.
    • (1967) Nature , vol.216 , Issue.5111 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 144
    • 0027989813 scopus 로고
    • Merozoite surface protein-3: A malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes
    • Oeuvray C., Bouharoun-Tayoun H., Gras-Masse H., Bottius E., Kaidoh T., Aikawa M., Filgueira M.C., Tartar A., Druilhe P. Merozoite surface protein-3: A malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes. Blood 1994, 84(5):1594-1602.
    • (1994) Blood , vol.84 , Issue.5 , pp. 1594-1602
    • Oeuvray, C.1    Bouharoun-Tayoun, H.2    Gras-Masse, H.3    Bottius, E.4    Kaidoh, T.5    Aikawa, M.6    Filgueira, M.C.7    Tartar, A.8    Druilhe, P.9
  • 145
    • 0034064657 scopus 로고    scopus 로고
    • Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal
    • Oeuvray C., Theisen M., Rogier C., Trape J.F., Jepsen S., Druilhe P. Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal. Infect. Immun. 2000, 68(5):2617-2620.
    • (2000) Infect. Immun. , vol.68 , Issue.5 , pp. 2617-2620
    • Oeuvray, C.1    Theisen, M.2    Rogier, C.3    Trape, J.F.4    Jepsen, S.5    Druilhe, P.6
  • 147
    • 72449167895 scopus 로고    scopus 로고
    • Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c
    • Olugbile S., Kulangara C., Bang G., Bertholet S., Suzarte E., Villard V., Frank G., Audran R., Razaname A., Nebie I., et al. Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c. Infect. Immun. 2009, 77(12):5701-5709.
    • (2009) Infect. Immun. , vol.77 , Issue.12 , pp. 5701-5709
    • Olugbile, S.1    Kulangara, C.2    Bang, G.3    Bertholet, S.4    Suzarte, E.5    Villard, V.6    Frank, G.7    Audran, R.8    Razaname, A.9    Nebie, I.10
  • 148
    • 76749138933 scopus 로고    scopus 로고
    • Malaria vaccines-The long synthetic peptide approach: Technical and conceptual advancements
    • Olugbile S., Habel C., Servis C., Spertini F., Verdini A., Corradin G. Malaria vaccines-The long synthetic peptide approach: Technical and conceptual advancements. Curr. Opin. Mol. Ther. 2010, 12(1):64-76.
    • (2010) Curr. Opin. Mol. Ther. , vol.12 , Issue.1 , pp. 64-76
    • Olugbile, S.1    Habel, C.2    Servis, C.3    Spertini, F.4    Verdini, A.5    Corradin, G.6
  • 150
    • 52049105157 scopus 로고    scopus 로고
    • Protective CD8 T cells against Plasmodium liver stages: Immunobiology of an 'unnatural' immune response
    • Overstreet M.G., Cockburn I.A., Chen Y.C., Zavala F. Protective CD8 T cells against Plasmodium liver stages: Immunobiology of an 'unnatural' immune response. Immunol. Rev. 2008, 225:272-283.
    • (2008) Immunol. Rev. , vol.225 , pp. 272-283
    • Overstreet, M.G.1    Cockburn, I.A.2    Chen, Y.C.3    Zavala, F.4
  • 151
    • 0026716363 scopus 로고
    • Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates
    • Pancake S.J., Holt G.D., Mellouk S., Hoffman S.L. Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates. J. Cell Biol. 1992, 117(6):1351-1357.
    • (1992) J. Cell Biol. , vol.117 , Issue.6 , pp. 1351-1357
    • Pancake, S.J.1    Holt, G.D.2    Mellouk, S.3    Hoffman, S.L.4
  • 152
    • 0024796883 scopus 로고
    • Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
    • Panina-Bordignon P., Tan A., Termijtelen A., Demotz S., Corradin G., Lanzavecchia A. Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur. J. Immunol. 1989, 19(12):2237-2242.
    • (1989) Eur. J. Immunol. , vol.19 , Issue.12 , pp. 2237-2242
    • Panina-Bordignon, P.1    Tan, A.2    Termijtelen, A.3    Demotz, S.4    Corradin, G.5    Lanzavecchia, A.6
  • 155
    • 0026592279 scopus 로고
    • Study of the safety and immunogenicity of the synthetic malaria SPf66 vaccine in children aged 1-14 years
    • Patarroyo G., Franco L., Amador R., Murillo L.A., Rocha C.L., Rojas M., Patarroyo M.E. Study of the safety and immunogenicity of the synthetic malaria SPf66 vaccine in children aged 1-14 years. Vaccine 1992, 10(3):175-178.
    • (1992) Vaccine , vol.10 , Issue.3 , pp. 175-178
    • Patarroyo, G.1    Franco, L.2    Amador, R.3    Murillo, L.A.4    Rocha, C.L.5    Rojas, M.6    Patarroyo, M.E.7
  • 156
    • 17744420399 scopus 로고
    • Immune mechanisms underlying the premunition against Plasmodium falciparum malaria
    • Perignon J.L., Druilhe P. Immune mechanisms underlying the premunition against Plasmodium falciparum malaria. Mem. Inst. Oswaldo Cruz 1994, 89(Suppl. 2):51-53.
    • (1994) Mem. Inst. Oswaldo Cruz , vol.89 , Issue.SUPPL. 2 , pp. 51-53
    • Perignon, J.L.1    Druilhe, P.2
  • 157
    • 0034945823 scopus 로고    scopus 로고
    • Long synthetic peptides encompassing the Plasmodium falciparum LSA3 are the target of human B and T cells and are potent inducers of B helper, T helper and cytolytic T cell responses in mice
    • Perlaza B.L., Sauzet J.P., Balde A.T., Brahimi K., Tall A., Corradin G., Druilhe P. Long synthetic peptides encompassing the Plasmodium falciparum LSA3 are the target of human B and T cells and are potent inducers of B helper, T helper and cytolytic T cell responses in mice. Eur. J. Immunol. 2001, 31(7):2200-2209.
    • (2001) Eur. J. Immunol. , vol.31 , Issue.7 , pp. 2200-2209
    • Perlaza, B.L.1    Sauzet, J.P.2    Balde, A.T.3    Brahimi, K.4    Tall, A.5    Corradin, G.6    Druilhe, P.7
  • 158
    • 0024449922 scopus 로고
    • Characterizing T-cell epitopes in vaccine candidates
    • Pink J.R., Sinigaglia F. Characterizing T-cell epitopes in vaccine candidates. Immunol. Today 1989, 10(12):408-409.
    • (1989) Immunol. Today , vol.10 , Issue.12 , pp. 408-409
    • Pink, J.R.1    Sinigaglia, F.2
  • 160
    • 0019842023 scopus 로고
    • Persistence of neutralizing antibody 30-35 years after immunization with 17D yellow fever vaccine
    • Poland J.D., Calisher C.H., Monath T.P., Downs W.G., Murphy K. Persistence of neutralizing antibody 30-35 years after immunization with 17D yellow fever vaccine. Bull. World Health Organ. 1981, 59(6):895-900.
    • (1981) Bull. World Health Organ. , vol.59 , Issue.6 , pp. 895-900
    • Poland, J.D.1    Calisher, C.H.2    Monath, T.P.3    Downs, W.G.4    Murphy, K.5
  • 161
    • 70349158714 scopus 로고    scopus 로고
    • New developments in Plasmodium vivax malaria: Severe disease and the rise of chloroquine resistance
    • Price R.N., Douglas N.M., Anstey N.M. New developments in Plasmodium vivax malaria: Severe disease and the rise of chloroquine resistance. Curr. Opin. Infect. Dis. 2009, 22(5):430-435.
    • (2009) Curr. Opin. Infect. Dis. , vol.22 , Issue.5 , pp. 430-435
    • Price, R.N.1    Douglas, N.M.2    Anstey, N.M.3
  • 162
    • 11144353591 scopus 로고    scopus 로고
    • A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
    • Reece W.H., Pinder M., Gothard P.K., Milligan P., Bojang K., Doherty T., Plebanski M., Akinwunmi P., Everaere S., Watkins K.R., et al. A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. Nat. Med. 2004, 10(4):406-410.
    • (2004) Nat. Med. , vol.10 , Issue.4 , pp. 406-410
    • Reece, W.H.1    Pinder, M.2    Gothard, P.K.3    Milligan, P.4    Bojang, K.5    Doherty, T.6    Plebanski, M.7    Akinwunmi, P.8    Everaere, S.9    Watkins, K.R.10
  • 163
    • 0020667655 scopus 로고
    • High-performance liquid chromatography of proteins
    • Regnier F.E. High-performance liquid chromatography of proteins. Methods Enzymol. 1983, 91:137-190.
    • (1983) Methods Enzymol. , vol.91 , pp. 137-190
    • Regnier, F.E.1
  • 164
    • 0029072487 scopus 로고
    • CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: Evidence that localization of peptide-specific CTLs is crucial for protection against malaria
    • Renggli J., Valmori D., Romero J.F., Eberl G., Romero P., Betschart B., Corradin G. CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: Evidence that localization of peptide-specific CTLs is crucial for protection against malaria. Immunol. Lett. 1995, 46(1-2):199-205.
    • (1995) Immunol. Lett. , vol.46 , Issue.1-2 , pp. 199-205
    • Renggli, J.1    Valmori, D.2    Romero, J.F.3    Eberl, G.4    Romero, P.5    Betschart, B.6    Corradin, G.7
  • 167
    • 0025010601 scopus 로고
    • Studies in Owl monkeys leading to the development of a synthetic vaccine against the asexual blood stages of plasmodium-falciparum
    • Rodriguez R., Moreno A., Guzman F., Calvo M., Patarroyo M.E. Studies in Owl monkeys leading to the development of a synthetic vaccine against the asexual blood stages of plasmodium-falciparum. Am. J. Trop. Med. Hyg. 1990, 43(4):339-354.
    • (1990) Am. J. Trop. Med. Hyg. , vol.43 , Issue.4 , pp. 339-354
    • Rodriguez, R.1    Moreno, A.2    Guzman, F.3    Calvo, M.4    Patarroyo, M.E.5
  • 169
    • 0029559716 scopus 로고
    • Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein
    • Roggero M.A., Filippi B., Church P., Hoffman S.L., Blum-Tirouvanziam U., Lopez J.A., Esposito F., Matile H., Reymond C.D., Fasel N., et al. Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein. Mol. Immunol. 1995, 32(17-18):1301-1309.
    • (1995) Mol. Immunol. , vol.32 , Issue.17-18 , pp. 1301-1309
    • Roggero, M.A.1    Filippi, B.2    Church, P.3    Hoffman, S.L.4    Blum-Tirouvanziam, U.5    Lopez, J.A.6    Esposito, F.7    Matile, H.8    Reymond, C.D.9    Fasel, N.10
  • 170
    • 0033830013 scopus 로고    scopus 로고
    • The synthetic, oxidized C-terminal fragment of the Plasmodium berghei circumsporozoite protein elicits a high protective response
    • Roggero M.A., Meraldi V., Lopez J.A., Eberl G., Romero J.C., Matile H., Betschart B., Corradin G., Renggli J. The synthetic, oxidized C-terminal fragment of the Plasmodium berghei circumsporozoite protein elicits a high protective response. Eur. J. Immunol. 2000, 30(9):2679-2685.
    • (2000) Eur. J. Immunol. , vol.30 , Issue.9 , pp. 2679-2685
    • Roggero, M.A.1    Meraldi, V.2    Lopez, J.A.3    Eberl, G.4    Romero, J.C.5    Matile, H.6    Betschart, B.7    Corradin, G.8    Renggli, J.9
  • 171
    • 0025025581 scopus 로고
    • Isolation and characterization of protective cytolytic T cells in a rodent malaria model system
    • Romero P., Maryanski J.L., Cordey A.S., Corradin G., Nussenzweig R.S., Zavala F. Isolation and characterization of protective cytolytic T cells in a rodent malaria model system. Immunol. Lett. 1990, 25(1-3):27-31.
    • (1990) Immunol. Lett. , vol.25 , Issue.1-3 , pp. 27-31
    • Romero, P.1    Maryanski, J.L.2    Cordey, A.S.3    Corradin, G.4    Nussenzweig, R.S.5    Zavala, F.6
  • 172
    • 0028231302 scopus 로고
    • Facile synthesis of homogeneous artificial proteins
    • Rose K. Facile synthesis of homogeneous artificial proteins. J. Am. Chem. Soc. 1994, 116(1):30-33.
    • (1994) J. Am. Chem. Soc. , vol.116 , Issue.1 , pp. 30-33
    • Rose, K.1
  • 173
    • 0028862141 scopus 로고
    • A synthetic peptide-based polyoxime vaccine construct of high purity and activity
    • Rose K., Zeng W., Brown L.E., Jackson D.C. A synthetic peptide-based polyoxime vaccine construct of high purity and activity. Mol. Immunol. 1995, 32(14-15):1031-1037.
    • (1995) Mol. Immunol. , vol.32 , Issue.14-15 , pp. 1031-1037
    • Rose, K.1    Zeng, W.2    Brown, L.E.3    Jackson, D.C.4
  • 176
    • 0025116161 scopus 로고
    • Immunization of owl monkeys with a combination of Plasmodium falciparum asexual blood-stage synthetic peptide antigens
    • Ruebush T.K., Campbell G.H., Moreno A., Patarroyo M.E., Collins W.E. Immunization of owl monkeys with a combination of Plasmodium falciparum asexual blood-stage synthetic peptide antigens. Am. J. Trop. Med. Hyg. 1990, 43(4):355-366.
    • (1990) Am. J. Trop. Med. Hyg. , vol.43 , Issue.4 , pp. 355-366
    • Ruebush, T.K.1    Campbell, G.H.2    Moreno, A.3    Patarroyo, M.E.4    Collins, W.E.5
  • 177
    • 0025729844 scopus 로고
    • Studies on the humoral immune response to a synthetic vaccine against Plasmodium falciparum malaria
    • Salcedo M., Barreto L., Rojas M., Moya R., Cote J., Patarroyo M.E. Studies on the humoral immune response to a synthetic vaccine against Plasmodium falciparum malaria. Clin. Exp. Immunol. 1991, 84(1):122-128.
    • (1991) Clin. Exp. Immunol. , vol.84 , Issue.1 , pp. 122-128
    • Salcedo, M.1    Barreto, L.2    Rojas, M.3    Moya, R.4    Cote, J.5    Patarroyo, M.E.6
  • 178
    • 78650598833 scopus 로고    scopus 로고
    • Experimental human challenge infections can accelerate clinical malaria vaccine development
    • Sauerwein R.W., Roestenberg M., Moorthy V.S. Experimental human challenge infections can accelerate clinical malaria vaccine development. Nat. Rev. Immunol. 2011, 11(1):57-64.
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.1 , pp. 57-64
    • Sauerwein, R.W.1    Roestenberg, M.2    Moorthy, V.S.3
  • 179
    • 77955536057 scopus 로고
    • Ueber einige aus asparagisäure entstchende producte
    • Schaal E. Ueber einige aus asparagisäure entstchende producte. Leibig's Annalen der Chemie 1871, 157:24-34.
    • (1871) Leibig's Annalen der Chemie , vol.157 , pp. 24-34
    • Schaal, E.1
  • 180
    • 0023714070 scopus 로고
    • Enzymatic activity of a synthetic 99 residue protein corresponding to the putative HIV-1 protease
    • Schneider J., Kent S.B. Enzymatic activity of a synthetic 99 residue protein corresponding to the putative HIV-1 protease. Cell 1988, 54(3):363-368.
    • (1988) Cell , vol.54 , Issue.3 , pp. 363-368
    • Schneider, J.1    Kent, S.B.2
  • 181
    • 0026525457 scopus 로고
    • Constructing proteins by dovetailing unprotected synthetic peptides: Backbone-engineered HIV protease
    • Schnolzer M., Kent S.B. Constructing proteins by dovetailing unprotected synthetic peptides: Backbone-engineered HIV protease. Science 1992, 256(5054):221-225.
    • (1992) Science , vol.256 , Issue.5054 , pp. 221-225
    • Schnolzer, M.1    Kent, S.B.2
  • 182
    • 0023483210 scopus 로고
    • Gamma-interferon, Cd8+ T-cells and antibodies required for immunity to malaria sporozoites
    • Schofield L., Villaquiran J., Ferreira A., Schellekens H., Nussenzweig R., Nussenzweig V. Gamma-interferon, Cd8+ T-cells and antibodies required for immunity to malaria sporozoites. Nature 1987, 330(6149):664-666.
    • (1987) Nature , vol.330 , Issue.6149 , pp. 664-666
    • Schofield, L.1    Villaquiran, J.2    Ferreira, A.3    Schellekens, H.4    Nussenzweig, R.5    Nussenzweig, V.6
  • 183
    • 84858772616 scopus 로고
    • Coenzym-a-Modellversuche Zur Biologischen Acylierungsreaktion-Uber Die Reaktionsfahigkeit Von Thiolcarbonsauren Und Ihren Estern
    • Schwyzer R. Coenzym-a-Modellversuche Zur Biologischen Acylierungsreaktion-Uber Die Reaktionsfahigkeit Von Thiolcarbonsauren Und Ihren Estern. Helvetica Chimica Acta 1953, 36(2):414-424.
    • (1953) Helvetica Chimica Acta , vol.36 , Issue.2 , pp. 414-424
    • Schwyzer, R.1
  • 184
    • 33749099648 scopus 로고
    • Total synthesis of adrenocorticotrophic hormone
    • Schwyzer R., Sieber P. Total synthesis of adrenocorticotrophic hormone. Nature 1963, 199(488):172.
    • (1963) Nature , vol.199 , Issue.488 , pp. 172
    • Schwyzer, R.1    Sieber, P.2
  • 186
    • 12444283342 scopus 로고
    • A new method of forming peptide bonds
    • Sheehan J.C., Hess G.P. A new method of forming peptide bonds. J. Am. Chem. Soc. 1955, 77(4):1067-1068.
    • (1955) J. Am. Chem. Soc. , vol.77 , Issue.4 , pp. 1067-1068
    • Sheehan, J.C.1    Hess, G.P.2
  • 187
    • 4344561703 scopus 로고    scopus 로고
    • Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design
    • Singh S., Soe S., Mejia J.P., Roussilhon C., Theisen M., Corradin G., Druilhe P. Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design. J. Infect. Dis. 2004, 190(5):1010-1018.
    • (2004) J. Infect. Dis. , vol.190 , Issue.5 , pp. 1010-1018
    • Singh, S.1    Soe, S.2    Mejia, J.P.3    Roussilhon, C.4    Theisen, M.5    Corradin, G.6    Druilhe, P.7
  • 190
    • 33947114334 scopus 로고    scopus 로고
    • Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa
    • Sirima S.B., Nebie I., Ouedraogo A., Tiono A.B., Konate A.T., Gansane A., Derme A.I., Diarra A., Soulama I., Cuzzin-Ouattara N., et al. Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa. Vaccine 2007, 25(14):2723-2732.
    • (2007) Vaccine , vol.25 , Issue.14 , pp. 2723-2732
    • Sirima, S.B.1    Nebie, I.2    Ouedraogo, A.3    Tiono, A.B.4    Konate, A.T.5    Gansane, A.6    Derme, A.I.7    Diarra, A.8    Soulama, I.9    Cuzzin-Ouattara, N.10
  • 191
    • 80052844191 scopus 로고    scopus 로고
    • Protection against malaria by MSP3 candidate vaccine
    • Sirima S., Cousens S., Druilhe P. Protection against malaria by MSP3 candidate vaccine. N. Engl. J. Med. 2011, 365(11):1062-1064.
    • (2011) N. Engl. J. Med. , vol.365 , Issue.11 , pp. 1062-1064
    • Sirima, S.1    Cousens, S.2    Druilhe, P.3
  • 192
    • 0030789141 scopus 로고    scopus 로고
    • Thrombospondin-related adhesive protein (TRAP) of Plasmodium berghei and parasite motility
    • Spaccapelo R., Naitza S., Robson K.J., Crisanti A. Thrombospondin-related adhesive protein (TRAP) of Plasmodium berghei and parasite motility. Lancet 1997, 350(9074):335.
    • (1997) Lancet , vol.350 , Issue.9074 , pp. 335
    • Spaccapelo, R.1    Naitza, S.2    Robson, K.J.3    Crisanti, A.4
  • 194
    • 0036074405 scopus 로고    scopus 로고
    • Establishment of intein-mediated protein ligation under denaturing conditions: C-terminal labeling of a single-chain antibody for biochip screening
    • Sydor J.R., Mariano M., Sideris S., Nock S. Establishment of intein-mediated protein ligation under denaturing conditions: C-terminal labeling of a single-chain antibody for biochip screening. Bioconjug. Chem. 2002, 13(4):707-712.
    • (2002) Bioconjug. Chem. , vol.13 , Issue.4 , pp. 707-712
    • Sydor, J.R.1    Mariano, M.2    Sideris, S.3    Nock, S.4
  • 195
    • 0025099759 scopus 로고
    • Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria
    • Tam J.P., Clavijo P., Lu Y.A., Nussenzweig V., Nussenzweig R., Zavala F. Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. J. Exp. Med. 1990, 171(1):299-306.
    • (1990) J. Exp. Med. , vol.171 , Issue.1 , pp. 299-306
    • Tam, J.P.1    Clavijo, P.2    Lu, Y.A.3    Nussenzweig, V.4    Nussenzweig, R.5    Zavala, F.6
  • 196
    • 0031040547 scopus 로고    scopus 로고
    • Cloning and cross-species comparison of the thrombospondin-related anonymous protein (TRAP) gene from Plasmodium knowlesi, Plasmodium vivax and Plasmodium gallinaceum
    • Templeton T.J., Kaslow D.C. Cloning and cross-species comparison of the thrombospondin-related anonymous protein (TRAP) gene from Plasmodium knowlesi, Plasmodium vivax and Plasmodium gallinaceum. Mol. Biochem. Parasitol. 1997, 84(1):13-24.
    • (1997) Mol. Biochem. Parasitol. , vol.84 , Issue.1 , pp. 13-24
    • Templeton, T.J.1    Kaslow, D.C.2
  • 197
    • 0031975242 scopus 로고    scopus 로고
    • The glutamate-rich protein (GLURP) of Plasmodium falciparum is a target for antibody-dependent monocyte-mediated inhibition of parasite growth in vitro
    • Theisen M., Soe S., Oeuvray C., Thomas A.W., Vuust J., Danielsen S., Jepsen S., Druilhe P. The glutamate-rich protein (GLURP) of Plasmodium falciparum is a target for antibody-dependent monocyte-mediated inhibition of parasite growth in vitro. Infect. Immun. 1998, 66(1):11-17.
    • (1998) Infect. Immun. , vol.66 , Issue.1 , pp. 11-17
    • Theisen, M.1    Soe, S.2    Oeuvray, C.3    Thomas, A.W.4    Vuust, J.5    Danielsen, S.6    Jepsen, S.7    Druilhe, P.8
  • 198
    • 0034666704 scopus 로고    scopus 로고
    • Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing
    • Theisen M., Soe S., Jessing S.G., Okkels L.M., Danielsen S., Oeuvray C., Druilhe P., Jepsen S. Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing. Vaccine 2000, 19(2-3):204-212.
    • (2000) Vaccine , vol.19 , Issue.2-3 , pp. 204-212
    • Theisen, M.1    Soe, S.2    Jessing, S.G.3    Okkels, L.M.4    Danielsen, S.5    Oeuvray, C.6    Druilhe, P.7    Jepsen, S.8
  • 201
    • 46349102897 scopus 로고    scopus 로고
    • Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: A prospective study in Papua, Indonesia
    • Tjitra E., Anstey N.M., Sugiarto P., Warikar N., Kenangalem E., Karyana M., Lampah D.A., Price R.N. Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: A prospective study in Papua, Indonesia. PLoS Med. 2008, 5(6):e128.
    • (2008) PLoS Med. , vol.5 , Issue.6
    • Tjitra, E.1    Anstey, N.M.2    Sugiarto, P.3    Warikar, N.4    Kenangalem, E.5    Karyana, M.6    Lampah, D.A.7    Price, R.N.8
  • 202
    • 34250021917 scopus 로고    scopus 로고
    • Glucagon and the glucagon receptor: Merrifield years at the interface of chemistry and biology
    • Unson C.G. Glucagon and the glucagon receptor: Merrifield years at the interface of chemistry and biology. Int. J. Pept. Res. Ther. 2007, 13(1-2):19-27.
    • (2007) Int. J. Pept. Res. Ther. , vol.13 , Issue.1-2 , pp. 19-27
    • Unson, C.G.1
  • 204
    • 0026703523 scopus 로고
    • Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination
    • Valmori D., Pessi A., Bianchi E., Corradin G. Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination. J. Immunol. 1992, 149(2):717-721.
    • (1992) J. Immunol. , vol.149 , Issue.2 , pp. 717-721
    • Valmori, D.1    Pessi, A.2    Bianchi, E.3    Corradin, G.4
  • 205
    • 0026158338 scopus 로고
    • Toward the elucidation of the mechanism of attachment and entry of malaria sporozoites into cells: Synthetic polypeptides from the circumsporozoite protein of Plasmodium falciparum bind Ca2+ and interact with model phospholipid membranes
    • Verdini A.S., Chiappinelli L., Zanobi A. Toward the elucidation of the mechanism of attachment and entry of malaria sporozoites into cells: Synthetic polypeptides from the circumsporozoite protein of Plasmodium falciparum bind Ca2+ and interact with model phospholipid membranes. Biopolymers 1991, 31(6):587-594.
    • (1991) Biopolymers , vol.31 , Issue.6 , pp. 587-594
    • Verdini, A.S.1    Chiappinelli, L.2    Zanobi, A.3
  • 206
    • 61749084617 scopus 로고    scopus 로고
    • Oxidative folding of synthetic polypeptides S-protected as tert-butylthio derivatives
    • Verdini A., Terenzi S., Brossard V., Roggero M., Corradin G. Oxidative folding of synthetic polypeptides S-protected as tert-butylthio derivatives. J. Pept. Sci. 2008, 14(12):1271-1282.
    • (2008) J. Pept. Sci. , vol.14 , Issue.12 , pp. 1271-1282
    • Verdini, A.1    Terenzi, S.2    Brossard, V.3    Roggero, M.4    Corradin, G.5
  • 207
    • 84858766260 scopus 로고    scopus 로고
    • Malaria Vaccine Development: 20 Years of Hopes, Hypes and Limited Achievements
    • Lausanne, Switzerland, E. Jirillo (Ed.)
    • Verdini A., Olugbile S., Corradin G., Pink P. Malaria Vaccine Development: 20 Years of Hopes, Hypes and Limited Achievements. Immune Response to Parasitic Infections 2010, 21-42. Lausanne, Switzerland. E. Jirillo (Ed.).
    • (2010) Immune Response to Parasitic Infections , pp. 21-42
    • Verdini, A.1    Olugbile, S.2    Corradin, G.3    Pink, P.4
  • 209
    • 0026675372 scopus 로고
    • A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei
    • Weiss W.R., Berzofsky J.A., Houghten R.A., Sedegah M., Hollindale M., Hoffman S.L. A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei. J. Immunol. 1992, 149(6):2103-2109.
    • (1992) J. Immunol. , vol.149 , Issue.6 , pp. 2103-2109
    • Weiss, W.R.1    Berzofsky, J.A.2    Houghten, R.A.3    Sedegah, M.4    Hollindale, M.5    Hoffman, S.L.6
  • 210
    • 79952193925 scopus 로고    scopus 로고
    • WHO, World Health Organization
    • World Health Organization World Malaria Report: 2010 2010, WHO.
    • (2010) World Malaria Report: 2010
  • 211
    • 0032749078 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins: Re-assessing the protein structure-function paradigm
    • Wright P.E., Dyson H.J. Intrinsically unstructured proteins: Re-assessing the protein structure-function paradigm. J. Mol. Biol. 1999, 293(2):321-331.
    • (1999) J. Mol. Biol. , vol.293 , Issue.2 , pp. 321-331
    • Wright, P.E.1    Dyson, H.J.2
  • 212
    • 0015147422 scopus 로고
    • Synthesis of naturally occurring polypeptides, problems of current research
    • Wünsch E. Synthesis of naturally occurring polypeptides, problems of current research. Angew. Chem. Int. Ed Engl. 1971, 10(11):786-795.
    • (1971) Angew. Chem. Int. Ed Engl. , vol.10 , Issue.11 , pp. 786-795
    • Wünsch, E.1
  • 213
    • 0014233399 scopus 로고
    • Zur synthese des glucagons. XIX Reindarstellung des synthetischen glucagons
    • Wünsch E., Jaeger E., Scharf R. Zur synthese des glucagons. XIX Reindarstellung des synthetischen glucagons. Chem. Ber. 1968, 101:3664-3667.
    • (1968) Chem. Ber. , vol.101 , pp. 3664-3667
    • Wünsch, E.1    Jaeger, E.2    Scharf, R.3
  • 214
    • 0019618495 scopus 로고
    • Totally synthetic crystalline ribonuclease A
    • Yajima H., Fujii N. Totally synthetic crystalline ribonuclease A. Biopolymers 1981, 20(9):1859-1867.
    • (1981) Biopolymers , vol.20 , Issue.9 , pp. 1859-1867
    • Yajima, H.1    Fujii, N.2
  • 216
    • 76649103701 scopus 로고    scopus 로고
    • The first protein ever synthesized in vitro-A personal reminiscence of the total synthesis of crystalline insulin
    • Zhang Y.S. The first protein ever synthesized in vitro-A personal reminiscence of the total synthesis of crystalline insulin. Sci. China Life Sci. 2010, 53(1):16-18.
    • (2010) Sci. China Life Sci. , vol.53 , Issue.1 , pp. 16-18
    • Zhang, Y.S.1
  • 217
    • 0037435877 scopus 로고    scopus 로고
    • Immunostimulating reconstituted influenza virosomes
    • Zurbriggen R. Immunostimulating reconstituted influenza virosomes. Vaccine 2003, 21(9-10):921-924.
    • (2003) Vaccine , vol.21 , Issue.9-10 , pp. 921-924
    • Zurbriggen, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.