Long-Term Sphere Culture Cannot Maintain a High Ratio of Cancer Stem Cells: A Mathematical Model and Experiment

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Peng, Tang ^a   Qinghua, Ma ^a   Zhenning, Tang ^a   Kaifa, Wang ^a   Jun, Jiang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER CELL; CANCER RESEARCH; CANCER STEM CELL; CELL DIFFERENTIATION; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL TRANSFORMATION; CONTROLLED STUDY; CULTURE TECHNIQUE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LONG TERM SPHERE CULTURE; MATHEMATICAL MODEL; ONCOLOGICAL PARAMETERS; BIOLOGICAL MODEL; METHODOLOGY; PATHOLOGY; TIME; TUMOR CELL LINE;

CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; HUMANS; MODELS, BIOLOGICAL; NEOPLASTIC STEM CELLS; TIME FACTORS;

EID: 84858754717     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025518     Document Type: Article

References (28)

1. Reya T, Morrison SJ, Clarke MF, Weissman IL, (2001) Stem cells, cancer, and cancer stem cells. Nature 414: 105-11.
2. Marx J, (2003) Mutant stem cells may seed cancer. Science 301: 1308-10.
3. Al-Hajj M, Clarke MF, (2004) Self-renewal and solid tumor stem cells. Oncogene 23: 7274-82.
4. Balic M, Lin H, Young L, Hawes D, Giuliano A, et al.(2006) Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 12: 5615-21.
5. Wicha MS, (2006) Cancer stem cells and metastasis: lethal seeds. Clin Cancer Res 12: 5606-7.
6. Abraham BK, Fritz P, McClellan M, Hauptvogel P, Athelogou M, et al.(2005) Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res 11: 1154-9.
7. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF, (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 100: 3983-8.
8. Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, et al.(2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65: 5506-11.
9. Yuan X, Curtin J, Xiong Y, Liu G, Waschsmann-Hogiu S, et al.(2004) Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23: 9392-400.
10. Cammareri P, Lombardo Y, Francipane MG, Bonventre S, Todaro M, et al.(2008) Isolation and culture of colon cancer stem cells. Methods Cell Biol 86: 311-24.
11. Zhong Y, Guan K, Guo S, Zhou C, Wang D, et al.(2010) Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells. Cancer Lett 299: 150-60.
12. Lim YC, Oh SY, Cha YY, Kim SH, Jin X, et al.(2011) Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas. Oral Oncol 47: 83-91.
13. Morrison SJ, Kimble J, (2006) Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441: 1068-74.
14. Caussinus E, Hirth F, (2007) Asymmetric stem cell division in development and cancer. Prog Mol Subcell Biol 45: 205-25.
15. Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, et al.(2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-15.
16. Phillips TM, McBride WH, Pajonk F, (2006) The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 98: 1777-85.
17. Haario H, Laine M, Mira A, et al.(2006) Dram: Efficient adaptive mcmc. Statistics and Computing 16: 339-54.
18. Tang SY, Xiao YN, (2008) Dynamic biosystems of single population (in Chinese) Beijing Science Press pp. 479-95.
19. Xue Y, Xi C, (2007) Numerical simulation for groundwater (in Chinese) Beijing Science Press.
20. Wang K, Tan W, Tang Y, Deng G, (2011) Numerical Diagnoses of Superinfection in Chronic Hepatitis B Viral Dynamics. Intervirology doi:10.1159/000321454.
21. Lukacs RU, Goldstein AS, Lawson DA, Cheng D, Witte ON, (2010) Isolation, cultivation and characterization of adult murine prostate stem cells. Nat Protoc 5: 702-13.
22. Shackleton M, Quintana E, Fearon ER, Morrison SJ, (2009) Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 138: 822-9.
23. Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, et al.(2004) Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64: 7011-21.
24. Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, et al.(2011) Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A 108: 7950-5.
25. Huang S, (2009) Non-genetic heterogeneity of cells in development: more than just noise. Development 136: 3853-62.
26. Miyazono K, (2009) Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. Proc Jpn Acad Ser B Phys Biol Sci 85: 314-23.
27. Kim S, Goel S, Alexander CM, (2011) Differentiation Generates Paracrine Cell Pairs That Maintain Basaloid Mouse Mammary Tumors: Proof of Concept. PLoS One 6: e19310.
28. Stewart JM, Shaw PA, Gedye C, Bernardini MQ, Neel BG, et al.(2011) Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells. Proc Natl Acad Sci U S A 109: 6468-73.