Numerical diagnoses of superinfection in chronic hepatitis B viral dynamics

Intervirology

Volumn 54, Issue 6, 2011, Pages 349-356

  Wang, Kaifa ^a   Tan, Wenting ^b   Tang, Yingzi ^b   Deng, Guohong ^b  

^a School of Biomedical Engineering and Medical Imaging   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Chronic hepatitis B; Covalently closed circular DNA; HBV DNA load; Mathematical model; Spontaneous fluctuation; Superinfection

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; BILIRUBIN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ARTICLE; CHEMICAL REACTION KINETICS; CLINICAL ARTICLE; CLINICAL STUDY; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CELL; MATHEMATICAL MODEL; PARAMETER; PHENOTYPE; PRIORITY JOURNAL; SUPERINFECTION; VIRION; VIRUS LOAD;

ALGORITHMS; DNA, VIRAL; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MODELS, BIOLOGICAL; SUPERINFECTION; VIRAL LOAD;

HEPATITIS B VIRUS;

EID: 80053974465     PISSN: 03005526     EISSN: 14230100     Source Type: Journal    
DOI: 10.1159/000321454     Document Type: Article

References (32)

1. Lai CL, Dienstag J, Schiff E, Leung NWY, Atkins M, Hunt C, Brown N, Woessner M, Boehme R, Condreay L: Prevalence and clinical correlates of YMDD variants during lamivudine therapy for patients with chronic hepatitis B. Clin Infect Dis 2003; 36: 687-696. (Pubitemid 36337972)
2. Hoofnagle JH, Doo E, Liang TJ, Fleischer R, Lok AS: Management of hepatitis B: summary of a clinical research workshop. Hepatology 2007; 45: 1056-1075. (Pubitemid 46646501)
3. Lewin SR, Ribeiro RM, Walters T, Lau GK, Bowden S, Locarnini S, Perelson AS: Analysis of hepatitis B viral load decline under potent therapy: complex decay profiles observed. Hepatology 2001; 34: 1012-1020. (Pubitemid 33032037)
4. Dahari H, Shudo E, Ribeiro RM, Perelson AS: Modeling complex decay profiles of hepatitis B virus during antiviral therapy. Hepatology 2009; 49: 32-38.
5. Chun YK, Kimm JY, Woo HJ, Oh SM, Kang I, Ha J, Kim SS: No significant correlation exists between core promoter mutations, viral replication, and liver damage in chronic hepatitis B infection. Hepatology 2000; 32: 1154-1162.
6. Deng G, Wang Z, Wang Y, Wang K, Fan Y: Dynamic determination and analysis of serum virus load in patients with chronic HBV infection. World Chin J Digestol 2004; 12: 862-865. (Pubitemid 39341167)
7. Tuttleman J, Pourcel C, Summers J: Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell 1986; 47: 451-460. (Pubitemid 17210159)
8. Zeuzem S, de Man RA, Honkoop P, Roth WK, Schalm SW, Schmidt JM: Dynamics of hepatitis B virus infection in viva. J Hepatol 1997; 21: 431-436. (Pubitemid 27390888)
9. Ciupe SM, Ribeiro RM, Nelson PW, Perelson AS: Modeling the mechanisms of acute hepatitis B virus infection. J Theor Biol 2007; 247: 23-35. (Pubitemid 46770792)
10. Nowak MA, Bonhoeffer S, Hill AM, Boehme R, Thomas HC, McDade H: Viral dynamics in hepatitis B Virus Infection. Proc Natl Acad Sci USA 1996; 93: 4398-4402. (Pubitemid 26144299)
11. Nowak MA, May RM: Virus Dynamics. Oxford, Oxford University Press, 2000.
12. Perelson AS, Nelson PW: Mathematical analysis of HIV-1 dynamics in vivo. SIAM Rev 1999; 41: 3-44. (Pubitemid 129723746)
13. Michalopoulos GK: Liver regeneration. J Cell Physiol 2007; 213: 286-300. (Pubitemid 47509705)
14. Ciupe SM, Ribeiro RM, Nelson PW, Dusheiko G, Perelson AS: The role of cells refractory to productive infection in acute hepatitis B viral dynamics. Proc Natl Acad Sci USA 2007; 104: 5050-5055. (Pubitemid 47186174)
15. Hews S, Eikenberry S, Nagy JD, Kuang Y: Rich dynamics of a hepatitis B viral infection model with logistic hepatocyte growth. J Math Biol 2010; 60: 573-590.
16. Eikenberry S, Hews S, Nagy JD, Kuang Y: The dynamics of a delay model of HBV infection with logistic hepatocyte growth. Math Biosci Eng 2009; 6: 283-299.
17. Gourley SA, Kuang Y, Nagy JD: Dynamics of a delay differential equation model of hepatitis B virus infection. J Biol Dyn 2008; 2: 140-153.
18. Min L, Su Y, Kuang Y: Mathematical analysis of a basic virus infection model with application to HBV infection. Rocky Mount. J Math 2008; 38: 1573-1585.
19. Lau GK, Tsiang M, Hou J, Yuen S, Carman WF, Zhang L, Gibbs CS, Lam S: Combination therapy with lamivudine and famciclovir for chronic hepatitis B-infected Chinese patients: a viral dynamics study. Hepatology 2000; 32: 394-399. (Pubitemid 30616013)
20. Rossotti FJC, Rossotti H: The Determination of Stability Constants. New York, McGraw-Hill, 1961.
21. Guidotti LG, Rochford R, Chung J, Shapiro M, Purcell R, Chisari FV: Viral clearance without destruction of infected cells during acute HBV Infection. Science 1999; 284: 825-829. (Pubitemid 29291352)
22. Liu WM, Levin SA, Iwasa Y: Influence of nonlinear incidence rates upon the behavior of SIRS epidemiological models. J Math Biol 1986; 23: 187-204. (Pubitemid 16153721)
23. Ruan S, Wang W: Dynamical behavior of an epidemic model with a nonlinear incidence rate. J Diff Equa 2003; 188: 135-163. (Pubitemid 36233149)
24. Xiao D, Ruan S: Global analysis of an epidemic model with nonmonotone incidence rate. Math Biosci 2007; 208: 419-429. (Pubitemid 47101853)
25. Whalley SA, Murray JM, Brown D, Webster GJM, Emery VC, G.M. Dusheiko GM, Perelson AS: Kinetics of Acute Hepatitis B Virus Infection in Humans. J Exp Med 2001; 93: 847-853. (Pubitemid 32524534)
26. Xue Y, Xie C: Numerical Simulation for Groundwater (in Chinese). Beijing, Science Press, 2007.
27. Wang K, Wang W, Liu X: Viral infection model with periodic lytic immune response. Chaos Solitons Fractals 2006; 28: 90-99. (Pubitemid 41491974)
28. Wang K, Wang W, Pang H, Liu X: Complex dynamic behavior in a viral model with delayed immune response. Physica D 2007; 226: 197-208. (Pubitemid 46185615)
29. Lok ASF, Lai CL, Leung N, Yao GB, Cui ZY, Schiff ER, Dienstag JL, Heathcote EJ, Little NR, Griffiths DA, Gardner SD, Castiglia M: Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 2003; 125: 1714-1722. (Pubitemid 37500436)
30. Honkoop P, Niesters HGM, de Man RAM, Osterhaus ADME, Schalm SW: Lamivudine resistance in immunocompetent chronic hepatitis B. Incidence and patterns. J Hepatol 1997; 26: 1393-1395. (Pubitemid 27346654)
31. Allen MI, Deslauriers M, Andrews CW, Tipples GA, Walters KA, Tyrrell DLJ, Brown N, Condreay LD: Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Hepatology 1998; 27: 1670-1677. (Pubitemid 28264693)
32. Lai CL, Ratziu V, Yuen MF, Poynard T: Viral hepatitis B. Lancet 2003; 362: 2089-2094. (Pubitemid 38032767)