High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: Role of mitochondrial KATP channels

Cardiovascular Diabetology

Volumn 11, Issue , 2012, Pages

  Ichinomiya, Taiga ^a   Cho, Sungsam ^a   Higashijima, Ushio ^a   Matsumoto, Shuhei ^a   Maekawa, Takuji ^a   Sumikawa, Koji ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fasudil; Hyperglycemia; Mitochondrial KATP channels; Myocardial infarction; Postconditioning

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DIAZOXIDE; FASUDIL; GLUCOSE; PENTOBARBITAL; SODIUM CHLORIDE; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 5-HYDROXYDECANOIC ACID; DECANOIC ACID DERIVATIVE; DRUG DERIVATIVE; HYDROXYACID; MITOCHONDRIAL K(ATP) CHANNEL; POTASSIUM CHANNEL; PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART RATE; HYPERGLYCEMIA; ISCHEMIC POSTCONDITIONING; LOW DRUG DOSE; MALE; MEAN ARTERIAL PRESSURE; MITOCHONDRION; NONHUMAN; RAT; THORAX; ANIMAL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; HEART INFARCTION PREVENTION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REPERFUSION INJURY; SPRAGUE DAWLEY RAT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BLOOD GLUCOSE; DECANOIC ACIDS; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROXY ACIDS; HYPERGLYCEMIA; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MODELS, ANIMAL; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; POTASSIUM CHANNELS; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84858722694     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-11-28     Document Type: Article

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