Tat(48-60) peptide amino acid sequence is not unique in its cell penetrating properties and cell-surface glycosaminoglycans inhibit its cellular uptake

Journal of Controlled Release

Volumn 158, Issue 2, 2012, Pages 277-285

  Subrizi, Astrid ^a   Tuominen, Eva ^a   Bunker, Alex ^a   Róg, Tomasz ^b   Antopolsky, Maxim ^a   Urtti, Arto ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Cellular barrier; Gene delivery; Glycosaminoglycan; Non amphiphatic cell penetrating peptide; Tat peptide

Indexed keywords

CELLULAR BARRIERS; GENE DELIVERY; GLYCOSAMINOGLYCANS; NON-AMPHIPHATIC CELL PENETRATING PEPTIDE; TAT PEPTIDE;

AMINO ACIDS; ANTIGEN-ANTIBODY REACTIONS; CELL CULTURE; CELL MEMBRANES; DRUG DELIVERY; GENE TRANSFER; LIPID BILAYERS; LIPOSOMES; MOLECULAR BIOLOGY; PHOSPHOLIPIDS;

PEPTIDES;

AROMATIC AMINO ACID; CHONDROITIN SULFATE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; PEPTIDE DERIVATIVE; TAT(48-60) PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL SURFACE; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID BILAYER; LIPID MEMBRANE; LIPOPHILICITY; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN INTERACTION; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCYTOSIS; GLYCOSAMINOGLYCANS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84858704212     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.007     Document Type: Article

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