Conjugation of butadiene diepoxide with glutathione yields DNA adducts in vitro and in vivo

Chemical Research in Toxicology

Volumn 25, Issue 3, 2012, Pages 706-712

  Cho, Sung Hee ^a   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTADIENE DIEPOXIDE; DNA; GLUTATHIONE; GLUTATHIONE TRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; GLUTATHIONE METABOLISM; IN VITRO STUDY; IN VIVO STUDY; KINETICS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE ANALYSIS; RAT; SALMONELLA TYPHIMURIUM; STEADY STATE; STEREOISOMERISM; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; CROSS-LINKING REAGENTS; DNA ADDUCTS; EPOXY COMPOUNDS; GLUTATHIONE; LIVER; MICE; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHI;

MUS; RATTUS; SALMONELLA TYPHIMURIUM;

EID: 84858686225     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200471x     Document Type: Article

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