Anthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteria

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Sun, Chen ^a   Fang, Hui ^a   Xie, Tao ^a   Auth, Roger D ^a   Patel, Nayana ^b   Murray, Patrick R ^b,d   Snoy, Philip J ^c   Frucht, David M ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d BD Diagnostics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTHRAX TOXIN; GENTAMICIN; MITOGEN ACTIVATED PROTEIN KINASE; BACTERIAL ANTIGEN; BACTERIAL TOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; APOPTOSIS; ARTICLE; BACILLUS ANTHRACIS; BLEEDING; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; INTESTINE EPITHELIUM; INTESTINE INJURY; MOUSE; NONHUMAN; PATHOLOGY; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; ULCER; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; ENTEROBACTERIACEAE INFECTION; HOST PATHOGEN INTERACTION; INTESTINE MUCOSA; PATHOGENICITY;

BACILLUS ANTHRACIS; ENTEROBACTERIACEAE; MURINAE; MUS;

ANIMALS; ANTHRAX; ANTIGENS, BACTERIAL; APOPTOSIS; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ENTEROBACTERIACEAE INFECTIONS; FEMALE; HOST-PATHOGEN INTERACTIONS; INTESTINAL MUCOSA; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL;

EID: 84858384009     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033583     Document Type: Article

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