Association between apolipoprotein E polymorphism and subclinic atherosclerosis in patients with type 1 diabetes mellitus

JCRPE Journal of Clinical Research in Pediatric Endocrinology

Volumn 4, Issue 1, 2012, Pages 8-13

  Atabek, Mehmet Emre ^a   Özkul, Yusuf ^b   Ekliǒlu, Beray Selver ^a   Kurtoǧlu, Selim ^b   Baykara, Murat ^b  

^a SELCUK UNIVERSITY   (Turkey)

^b ERCIYES UNIVERSITY   (Turkey)

Author keywords

Apolipoprotein E; Atherosclerosis; Carotid artery intima media thickness; Type 1 diabetes

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; TRIACYLGLYCEROL;

ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; DIABETIC PATIENT; DISEASE ASSOCIATION; DISEASE DURATION; DNA EXTRACTION; FEMALE; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; MICROALBUMINURIA; POLYMERASE CHAIN REACTION; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SYSTOLIC BLOOD PRESSURE;

ADOLESCENT; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD PRESSURE; CAROTID INTIMA-MEDIA THICKNESS; CHILD; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINEAR MODELS; MALE; MULTIVARIATE ANALYSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS; TRIGLYCERIDES;

EID: 84858383679     PISSN: 13085727     EISSN: 13085735     Source Type: Journal    
DOI: 10.4274/jcrpe.521     Document Type: Article

References (35)

1. Pyorala K, Laakso M, Uusitupa M. Diabetes and atherosclerosis: an epidemiologic view. Diabetes Metab Rev 1987;3:463-524.
2. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measrement with ultrasound imaging. Circulation 1986;74:1399-1406.
3. Pujia A, Gnasso A, Iraace C, Colonna A, Mattioli PL. Common carotid arterial wall thickness in NIDDM subjects. Diabetes Care 1994;17:1330-1336.
4. Lehmann ED, Riley WA, Clarkson P, Gosling RG. Noninvasive assessment of cardiovascular disease in diabetes mellitus. Lancet 1997;350:114-119.
5. Atabek ME, Kurtoglu S, Demir F, Baykara M. Relation of serum leptin and insulin- like growth factor-1 levels to intima-media thickness and functions of common carotid artery in children and adolescents with type 1 diabetes. Acta Paediatr 2004;93:1052-1057.
6. Cooper AD. Hepatic uptake of chylomicron remnants. J Lipid Res 1997;38:2173-2192.
7. Brouwer DA, van Doormaal JJ, Muskiet FA. Clinical chemistry of common Apolipoprotein E isoforms. J Chromatogr B Biomed Appl 1996;678:23-41.
8. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measrement with ultrasound imaging. Circulation 1986;74:1399-1406.
9. Soedamah-Muthu SS, Chaturvedi N, Toeller M, Ferriss B, Reboldi P, Michel G, Manes C, Fuller JH; EURODIAB Prospective Complications Study Group. Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study. Diabetes Care 2004;27:530-537.
10. Schneider JA, Bienias JL, Wilson RS, Berry-Kravis E, Evans DA, Bennett DA. The Apolipoprotein E ε4 allele increases the odds of chronic cerebral infarction detected at autopsy in older persons. Stroke 2005;36:954-959.
11. Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 1994;14:133-140.
12. Han Z, Heath SC, Shmulewitz D, Li W, Auerbach SB, Blundell ML, Lehner T, Ott J, Stoffel M, Friedman JM, Breslow JL. Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. Am J Med Genet 2002;110:234-242.
13. Mahley RW, Rall SC Jr. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet 2000;1:507-537.
14. Elosua R, Ordovas JM, Cupples LA, Fox CS, Polak JF, Wolf PA, D'Agostino RA Sr, O'Donnell CJ. Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. J Lipid Res 2004;45:1868-1875.
15. Wohlin M, Sundström J, Lannfelt L, Axelsson T, Syvänen AC, Andrén B, Basu S, Lind L. Apolipoprotein E epsilon 4 genotype is independently associated with increased intima-media thickness in a recessive pattern. Lipids 2007;42:451-456.
16. Beilby JP, Hunt CC, Palmer LJ, Chapman CM, Burley JP, McQuillan BM, Thompson PL, Hung J; Perth Carotid Ultrasound Disease Assessment Study. Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS). Stroke 2003;34:869-874.
17. Volcik KA, Barkley RA, Hutchinson RG, Mosley TH, Heiss G, Sharrett AR, Ballantyne CM, Boerwinkle E. Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants. Am J Epidemiol 2006;164:342-348.
18. Slooter AJ, Bots ML, Havekes LM, del Sol AI, Cruts M, Grobbee DE, Hofman A, Van Broeckhoven C, Witteman JC, van Duijn CM. Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam study. Stroke 2001;32:1947-1952.
19. Mahley RW, Rall SC Jr. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet 2000;1:507-537.
20. Tascilar N, Dursun A, Ankarali H, Mungan G, Sumbuloglu V, Ekem S, Bozdogan S, Baris S, Aciman E, Cabuk F. Relationship of Apo E polymorphism with lipoprotein(a), ApoA, ApoB and lipid levels in atherosclerotic infarct. J Neurol Sci 2009;277:17-21.
21. Fernández-Mestre MT, Yehirobi C, Montagnani S, Balbas O, Layrisse Z. Genetic variability of Apolipoprotein E in different populations from Venezuela. Dis Markers 2005;21:15-19.
22. Bennet AM, Di Angelantonio E, Ye Z, Wensley F, Dahlin A, Ahlbom A, Keavney B, Collins R, Wiman B, de Faire U, Danesh J. Association of Apolipoprotein E genotypes with lipid levels and coronary risk. JAMA 2007;298:1300-1311.
23. Frikke-Schmidt R, Tybjaerg-Hansen A, Steffensen R, Jensen G, Nordestgaard BG. Apolipoprotein E genotype: epsilon32 women are protected while epsilon43 and epsilon44 men are susceptible to ischemic heart disease: the Copenhagen City Heart Study. J Am Coll Cardiol 2000;35:1192-1199.
24. Järvisalo MJ, Raitakari M, Toikka JO, Putto-Laurila A, Rontu R, Laine S, Lehtimäki T, Rönnemaa T, Viikari J, Raitakari OT. Endothelial Dysfunction and increased arterial intima media thickness in children with type 1 diabetes. Circulation 2004;109:1750-1755.
25. Parikh A, Sochett EB, McCrindle BW, Dipchand A, Daneman A, Daneman D. Carotid artery distensibility and function in adolescents with type 1 diabetes. J Pediatr 2000;137:465-469.
26. Yavuz T, Akcay A, Omeroglu RE, Bundak R, Sukur M. Ultrasonic evaluation of early atherosclerosis in children and adolescents with type 1 diabetes mellitus. J Pediatr Endocrinol Metab 2002;15:1131-1136.
27. Gunczler P, Lanes R, Lopez E, Esaa S, Villarroel O, Revel-Chion R. Cardiac mass and function, carotid artery intimamedia thickness and lipoprotein (a) levels in children and adolescents with type 1 diabetes mellitus of short duration. J Pediatr Endocrinol Metab 2002;15:181-186.
28. Yamasaki Y, Kawamori R, Matsushima H, Nishizawa H, Kodama M, Kajimoto Y, Morishima T, Kamada T. Atherosclerosis in carotid artery of young IDDM patients monitored by ultrasound high-resolution B-mode imaging. Diabetes 1994;43:634-639.
29. Järvisalo MJ, Putto-Laurila A, Jartti L, Lehtimäki T, Solakivi T, Rönnemaa T, Raitakari OT. Carotid artery intima-media thickness in children with type 1 diabetes. Diabetes 2002;51:493-498.
30. Vastagh I, Horváth T, Nagy G, Varga T, Juhász E, Juhász V, Kollai M, Bereczki D, Somogyi A. Evolution and predictors of morphological and functional arterial changes in the course of type 1 diabetes mellitus. Diabetes Metab Res Rev 2010;26:646-655
31. Atabek ME, Pirgon O, Kurtoglu S, Imamoglu H. Evidence for an association between type 1 diabetes and premature carotid atherosclerosis in childhood. Pediatr Cardiol 2006;27:428-433.
32. Atabek ME, Kurtoglu S, Pirgon O, Baykara M. Arterial wall thickening and stiffening in children and adolescents with type 1 diabetes. Diabetes Res Clin Pract 2006;74:33-40.
33. Sorof JM, Alexandrov AV, Cardwell G, Portman RJ. Carotid artery intimalmedial thickness and left ventricular hypertrophy in children with elevated blood pressure. Pediatrics 2003;111:61-66.
34. Markus RA, Mack WJ, Azen SP, Hodis HN. Influence of lifestyle modification on atherosclerotic progression determined by ultrasonographic change in the common carotid intima-media thickness. Am J Clin Nutr 1997;65:1000-1004.
35. Zhu W, Huang X, He J, Li M, Neubauer H. Arterial intimamedia thickening and endothelial dysfunction in obese Chinese children. Eur J Pediatr 2005;164:337-344.