Relationship of apoE polymorphism with lipoprotein(a), apoA, apoB and lipid levels in atherosclerotic infarct

Journal of the Neurological Sciences

Volumn 277, Issue 1-2, 2009, Pages 17-21

  Tascilar, N ^a   Dursun, A ^a   Ankarali, H ^a   Mungan, G ^a   Sumbuloglu, V ^a   Ekem, S ^a   Bozdogan, S ^a   Baris, S ^a   Aciman, E ^a   Cabuk, F ^a  

^a Zonguldak Karaelmas Universitesi Tip Fakultesi   (Turkey)

Author keywords

Apolipoprotein A; Apolipoprotein B; Apolipoprotein E polymorphism; Lipids; Lipoprotein(a); Stroke

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN E; LIPID;

ADULT; AGED; ALLELE; ARTICLE; ATHEROSCLEROSIS; BRAIN INFARCTION; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENETIC POLYMORPHISM; HUMAN; HYPERTENSION; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STROKE;

ADULT; AGED; AGED, 80 AND OVER; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS A; APOLIPOPROTEINS B; ATHEROSCLEROSIS; CEREBRAL INFARCTION; CHOLESTEROL, LDL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIPOPROTEIN(A); LIPOPROTEINS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; STROKE;

EID: 58149314209     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2008.09.034     Document Type: Article

References (30)

1. Kim J.S., Han S.R., Chung S.W., Kim B.S., Lee K.S., Kim Y.I., et al. The apolipoprotein E epsilon4 haplotype is an important predictor for recurrence in ischemic cerebrovascular disease. J Neurol Sci 206 (2003) 31-37
2. Szolnoki Z., Somogyvári F., Kondacs A., Szabó M., and Fodor L. Evaluation of the interactions of common genetic mutations in stroke subtypes. J Neurol 249 (2002) 1391-1397
3. Catto A.J., McCormack L.J., Mansfield M.W., Carter A.M., Bamford J.M., Robinson P., et al. Apolipoprotein E polymorphism in cerebrovascular disease. Acta Neurol Scand 101 (2000) 399-404
4. Schneider J.A., Bienias J.L., Wilson R.S., Berry-Kravis E., Evans D.A., and Bennett D.A. The apolipoprotein E ε4 allele increases the odds of chronic cerebral infarction detected at autopsy in older persons. Stroke 36 (2005) 954-959
5. Macleod M.J., De Lange R.P., Breen G., Meiklejohn D., Lemmon H., and Clair D.S. Lack of association between apolipoprotein E genotype and ischaemic stroke in a Scottish population. Eur J Clin Invest 31 (2001) 570-573
6. Um J.Y., Kim H.M., Park H.S., Joo J.C., Kim K.Y., Kim Y.K., et al. Candidate genes of cerebral infarction and traditional classification in Koreans with cerebral infarction. Int J Neurosci 115 (2005) 743-756
7. Koschinsky M.L., and Marcovina S.M. Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity. Curr Opin Lipidol 15 (2004) 167-174
8. Akaike M., Azuma H., Kagawa A., Matsumoto K., Hayashi I., Tamura K., et al. Effect of aspirin treatment on serum concentrations of lipoprotein(a) in patients with atherosclerotic diseases. Clin Chem 48 (2002) 1454-1459
9. Jürgens G., Taddei-Peters W.C., Költringer P., Petek W., Chen Q., Greilberger J., et al. Lipoprotein(a) serum concentration and apolipoprotein(a) phenotype correlate with severity and presence of ischemic cerebrovascular disease. Stroke 26 (1995) 1841-1848
10. Marcovina S.M., and Koschinsky M.L. Evaluation of lipoprotein(a) as a prothrombotic factor: progress from bench to bedside. Curr Opin Lipidol 14 (2003) 361-366
11. Rigal M., Ruidavets J.B., Viguier A., Petit R., Perret B., Ferrieres J., et al. Lipoprotein(a) and risk of ischemic stroke in young adults. J Neurol Sci 252 (2007) 39-44
12. Duzenli S., Pirim I., Gepdiren A., and Deniz O. Apolipoprotein E polymorphism and stroke in a population from eastern Turkey. J Neurogenet 18 (2004) 365-375
13. Adams H.P., Bendixen B.H., Kappelle L.J., Biller J., Love B.B., Gordon D.L., et al. Classification of subtype of acute ischemic stroke definitions for use in a multicenter clinical trial. Stroke 24 (1993) 35-41
14. Pulkkinen A., Viitanen L., Kareinen A., Lehto S., and Laakso M. MspI polymorphism at +83 bp in intron 1 of the human apolipoprotein A1 gene is associated with elevated levels of HDL cholesterol and apolipoprotein A1 in nondiabetic subjects but not in type 2 diabetic patients with coronary heart disease. Diabetes Care 23 (2000) 791-795
15. Denti L., Cecchetti A., Annoni V., Merli M.F., Ablondi F., and Valenti G. The role of lipid profile in determining the risk of ischemic stroke in the elderly: a case-control study. Arch Gerontol Geriatr 37 (2003) 51-62
16. Reymer P.W., Groenemeyer B.E., van de Burg R., and Kastelein J.J. Apolipoprotein E genotyping on agarose gels. Clin Chem 41 (1995) 1046-1047
17. Gaw A., Murray H.M., and Brown E.A. Plasma lipoprotein(a) [Lp(a)] concentrations and cardiovascular events in the elderly: evidence from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis 180 (2005) 381-388
18. Walldius G., and Jungner I. Apolipoprotein A-1 versus HDL cholesterol in the prediction of risk for myocardial infarction and stroke. Curr Opin Cardiol 22 (2007) 359-367
19. Sun L., Li Z., Zhang H., Ma A., Liao Y., Wang D., et al. Pentanucleotide TTTTA repeat polymorphism of apolipoprotein(a) gene and plasma lipoprotein(a) are associated with ischemic and hemorrhagic stroke in Chinese. Stroke 34 (2003) 1617-1622
20. Shintani S., Kikuchi S., Hamaguchi H., and Shiigai T. High serum lipoprotein(a) levels are an independent risk factor for cerebral infarction. Stroke 24 (1993) 965-969
21. Holanda M.M., Filizola R.G., Costa M.J., Andrade R.V., and Silva J.A. Plasma lipoprotein(a) levels: a comparison between diabetic and non-diabetic patients with acute ischemic stroke. Arq Neuropsiquiatría 62 (2004) 233-236
22. Nakashima Y., Plump A.S., Raines E.W., Breslow J.L., and Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 14 (1994) 133-140
23. Couderc R., Mahieux F., Bailleul S., Fenelon G., Mary R., and Fermanian J. Prevalence of apolipoprotein E phenotypes in ischemic cerebrovascular disease. A case-control study. Stroke 24 (1993) 661-664
24. Davignon J., Gregg R.E., and Sing C.F. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 8 (1988) 1-21
25. Han Z., Heath S.C., Shmulewitz D., Li W., Auerbach S.B., Blundell M.L., et al. Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. Am J Med Genet 110 (2002) 234-242
26. Welty F.K., Lichtenstein A.H., Barrett P.H., Jener J.L., Dolnikowski G.G., and Schaefer E.J. Effects of apoE genotype on apoB-48 and apoB-100 kinetics with stable isotopes in humans. Arterioscler Thromb Vasc Biol 20 (2000) 1807-1810
27. Bednarska-Makaruk M., Rodo M., Markuszewski C., Rozenfeld A., Świderska M., Habrat B., et al. Polymorphisms of apolipoprotein E and angiotensin-converting enzyme genes and carotid atherosclerosis in heavy drinkers. Alcohol Alcohol 40 (2005) 274-282
28. Banerjee I., Gupta V., and Ganesh S. Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis. J Hum Genet 52 (2007) 205-219
29. Milionis H.J., Liberopoulos E., Goudevenos J., Bairaktari E.T., Seferiadis K., and Elisaf M.S. Risk factors for first-ever acute ischemic non-embolic stroke in elderly individuals. Int J Cardiol 99 (2005) 269-275
30. Qureshi A.I., Giles W.H., Croft J.B., Guterman L.R., and Hopkins L.N. Apolipoproteins A-1 and B and the likelihood of non-fatal stroke and myocardial infarction-data from the third national health and nutrition examination survey. Med Sci Monit 8 (2002) CR311-CR316