RSK2 signaling in medial habenula contributes to acute morphine analgesia

Neuropsychopharmacology

Volumn 37, Issue 5, 2012, Pages 1288-1296

  Darcq, Emmanuel ^a,b   Befort, Katia ^a   Koebel, Pascale ^a   Pannetier, Solange ^a   Mahoney, Megan K ^a,b   Gaveriaux Ruff, Claire ^a   Hanauer, André ^a   Kieffer, Brigitte L ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

habenular complex; knockout mice; mu opioid receptor; opiate; shRNA knockdown; withdrawal

Indexed keywords

MORPHINE; MU OPIATE RECEPTOR; NALOXONE; S6 KINASE; SHORT HAIRPIN RNA; SIGNAL PEPTIDE;

ADAPTIVE BEHAVIOR; ADENO ASSOCIATED VIRUS; ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; BRAIN; DRUG DOSE ESCALATION; DRUG EFFECT; DRUG SENSITIZATION; DRUG TOLERANCE; FEMALE; GENE; GENE DELETION; HABENULA; IN VIVO STUDY; INFORMATION PROCESSING; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; RSK2 GENE; TAIL;

ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; DRUG TOLERANCE; HABENULA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MORPHINE DEPENDENCE; MOTOR ACTIVITY; NALOXONE; NARCOTIC ANTAGONISTS; NOCICEPTION; PAIN MEASUREMENT; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC;

EID: 84858336787     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.316     Document Type: Article

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