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Volumn 34, Issue 1, 2012, Pages 88-97

A new multigene superfamily of Kunitz-type protease inhibitors from sea anemone Heteractis crispa

Author keywords

Gene family, Molecular diversity; Kunitz type protease inhibitor; Sea anemone

Indexed keywords

KUNITZ PROTEIN INHIBITOR; POLYPEPTIDE; PROTEINASE INHIBITOR; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; VENOM;

EID: 84858334167     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2011.09.022     Document Type: Article
Times cited : (34)

References (59)
  • 2
    • 0036027362 scopus 로고    scopus 로고
    • Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria)
    • DOI 10.1016/S0041-0101(01)00191-X, PII S004101010100191X
    • G. Anderluh, and P. Macek Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actinaria) Toxicon 40 2002 111 124 (Pubitemid 33016540)
    • (2002) Toxicon , vol.40 , Issue.2 , pp. 111-124
    • Anderluh, G.1    Macek, P.2
  • 3
    • 53049093899 scopus 로고    scopus 로고
    • Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1)
    • Y.A. Andreev, S.A. Kozlov, S.G. Koshelev, E.A. Ivanova, M.M. Monastyrnaya, and E.P. Kozlovskaya Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1) J Biol Chem 283 2008 23914 23921
    • (2008) J Biol Chem , vol.283 , pp. 23914-23921
    • Andreev, Y.A.1    Kozlov, S.A.2    Koshelev, S.G.3    Ivanova, E.A.4    Monastyrnaya, M.M.5    Kozlovskaya, E.P.6
  • 4
    • 0027467611 scopus 로고
    • The NMR solution structure of a Kunitz-type proteinase inhibitor from the sea anemone Stichodactyla helianthus
    • W. Antuch, K.D. Berndt, M.A. Chavez, J. Delfín, and K. Wüthrich The NMR solution structure of a Kunitz-type proteinase inhibitor from the sea anemone Stichodactyla helianthus Eur J Biochem 212 1993 675 684 (Pubitemid 23091712)
    • (1993) European Journal of Biochemistry , vol.212 , Issue.3 , pp. 675-684
    • Antuch, W.1    Berndt, K.D.2    Chavez, M.A.3    Delfin, J.4    Wuthrich, K.5
  • 6
    • 0026795399 scopus 로고
    • Determination of a high-quality nuclear magnetic resonance solution structure of the bovine pancreatic trypsin inhibitor and comparison with three crystal structures
    • K.D. Berndt, P. Guntert, L.P.M. Orbons, and K. Wuthrich Determination of a high-quality nuclear magnetic resonance solution structure of the bovine pancreatic trypsin inhibitor and comparison with three crystal structures J Mol Biol 227 1992 757 775
    • (1992) J Mol Biol , vol.227 , pp. 757-775
    • Berndt, K.D.1    Guntert, P.2    Orbons, L.P.M.3    Wuthrich, K.4
  • 7
    • 70350399657 scopus 로고    scopus 로고
    • Discovery and characterization of cnidarian peptide toxins that affect neuronal potassium ion channels
    • O. Castañeda, and A.L. Harvey Discovery and characterization of cnidarian peptide toxins that affect neuronal potassium ion channels Toxicon 54 2009 1119 1124
    • (2009) Toxicon , vol.54 , pp. 1119-1124
    • Castañeda, O.1    Harvey, A.L.2
  • 8
    • 0036057077 scopus 로고    scopus 로고
    • Precambrian animal life: Probable developmental and adult cnidarian forms from Southwest China
    • J.Y. Chen, P. Oliveri, F. Gao, S.Q. Dornbos, C.W. Li, and D.J. Bottjer Precambrian animal life: probable developmental and adult cnidarian forms from Southwest China Dev Biol 248 2002 182 196
    • (2002) Dev Biol , vol.248 , pp. 182-196
    • Chen, J.Y.1    Oliveri, P.2    Gao, F.3    Dornbos, S.Q.4    Li, C.W.5    Bottjer, D.J.6
  • 9
    • 0020645978 scopus 로고
    • Refined 2·5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex
    • Z. Chen, and W. Bode Refined 2.5 angstrom X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor: crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin pancreatic trypsin inhibitor complex J Mol Biol 164 1983 283 311 (Pubitemid 13123235)
    • (1983) Journal of Molecular Biology , vol.164 , Issue.2 , pp. 283-311
    • Chen, Z.1    Bode, W.2
  • 10
    • 8544229080 scopus 로고    scopus 로고
    • Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants
    • DOI 10.1016/j.jmb.2004.09.088, PII S0022283604012598
    • H. Czapinska, R. Helland, A.O. Smalas, and J. Otlewski Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants J Mol Biol 344 2004 1005 1020 (Pubitemid 39491246)
    • (2004) Journal of Molecular Biology , vol.344 , Issue.4 , pp. 1005-1020
    • Czapinska, H.1    Helland, R.2    Smalas, A.O.3    Otlewski, J.4
  • 12
    • 34147096629 scopus 로고    scopus 로고
    • Purification and partial characterization of a novel proteinase inhibitor from the sea anemone Stichodactyla helianthus
    • J. Diaz, V. Morera, J. Delfin, V. Huerta, G. Lima, and M. Rodriguez de la Vega Purification and partial characterization of a novel proteinase inhibitor from the sea anemone Stichodactyla helianthus Toxicon 36 1998 1275 1276
    • (1998) Toxicon , vol.36 , pp. 1275-1276
    • Diaz, J.1    Morera, V.2    Delfin, J.3    Huerta, V.4    Lima, G.5    Rodriguez De La Vega, M.6
  • 13
    • 33845351490 scopus 로고    scopus 로고
    • Molecular diversification in spider venoms: A web of combinatorial peptide libraries
    • DOI 10.1007/s11030-006-9050-4, Molecular Diversity of Proteins in Biological Offense and Defense Systems
    • P. Escoubas Molecular diversification in spider venoms: a web of combinatorial peptide libraries Mol Divers 10 2006 545 554 (Pubitemid 44885231)
    • (2006) Molecular Diversity , vol.10 , Issue.4 , pp. 545-554
    • Escoubas, P.1
  • 15
    • 0342617491 scopus 로고    scopus 로고
    • Genomic structure of a potassium channel toxin from Heteractis magnifica
    • DOI 10.1016/S0014-5793(97)01365-3, PII S0014579397013653
    • G.S. Gendeh, M.C. Chung, and K. Jeyaseelan Genomic structure of a potassium channel toxin from Heteractis magnifica FEBS Lett 418 1997 183 188 (Pubitemid 27514443)
    • (1997) FEBS Letters , vol.418 , Issue.1-2 , pp. 183-188
    • Gendeh, G.S.1    Chung, M.C.M.2    Jeyaseelan, K.3
  • 16
    • 70349393968 scopus 로고    scopus 로고
    • A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk
    • S. Gonzalez, M. Flo, M. Margenat, R. Duran, G. Gonzalez-Sapienza, and M. Grana A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk PLoS One 4 2009 e7009
    • (2009) PLoS One , vol.4 , pp. 7009
    • Gonzalez, S.1    Flo, M.2    Margenat, M.3    Duran, R.4    Gonzalez-Sapienza, G.5    Grana, M.6
  • 17
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
    • DOI 10.1002/elps.1150181505
    • N. Guex, and M.C. Peitsch SWISS-MODEL and the Swiss-PdbViewer, an environment for comparative protein modeling Electrophoresis 18 1997 2714 2723 (Pubitemid 28059943)
    • (1997) Electrophoresis , vol.18 , Issue.15 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 20
    • 33646191506 scopus 로고    scopus 로고
    • Amino acid sequence of RTX-A's isoform actinoporin from the sea anemone, Radianthus macrodactylus
    • A. Il'ina, A. Lipkin, E. Barsova, M. Issaeva, E. Leychenko, and K. Guzev Amino acid sequence of RTX-A's isoform actinoporin from the sea anemone, Radianthus macrodactylus Toxicon 47 2006 517 520
    • (2006) Toxicon , vol.47 , pp. 517-520
    • Il'Ina, A.1    Lipkin, A.2    Barsova, E.3    Issaeva, M.4    Leychenko, E.5    Guzev, K.6
  • 21
    • 0000856180 scopus 로고    scopus 로고
    • Amino Acid Sequences of Kunitz-type Protease Inhibitors from the Sea Anemone Actinia equina
    • M. Ishida, S. Minagawa, K. Miyauchi, K. Shimakura, Y. Nagashima, and K. Shiomi Amino acid sequences of Kunitz-type protease inhibitors from the sea anemone Actinia equina Fish Sci 63 1997 794 798 (Pubitemid 127443100)
    • (1997) Fisheries Science , vol.63 , Issue.5 , pp. 794-798
    • Ishida, M.1    Minagawa, S.2    Miyauchi, K.3    Shimakura, K.4    Nagashima, Y.5    Shiomi, K.6
  • 22
    • 52049099863 scopus 로고    scopus 로고
    • Genomic organization and cloning of novel genes encoding toxin-like peptides of three superfamilies from the spider Orinithoctonus huwena
    • L.P. Jiang, J.J. Chen, L. Peng, Y.Q. Zhang, X. Xiong, and S.P. Liang Genomic organization and cloning of novel genes encoding toxin-like peptides of three superfamilies from the spider Orinithoctonus huwena Peptides 29 2008 1679 1684
    • (2008) Peptides , vol.29 , pp. 1679-1684
    • Jiang, L.P.1    Chen, J.J.2    Peng, L.3    Zhang, Y.Q.4    Xiong, X.5    Liang, S.P.6
  • 23
    • 0141537020 scopus 로고    scopus 로고
    • The behavioral and developmental physiology of nematocysts
    • G. Kass-Simon, and A.A. Scappaticci Jr. The behavioral and developmental physiology of nematocysts Can J Zool 80 2002 1772 1794
    • (2002) Can J Zool , vol.80 , pp. 1772-1794
    • Kass-Simon, G.1    Scappaticci Jr., A.A.2
  • 25
    • 79251578979 scopus 로고    scopus 로고
    • The mining of toxin-like polypeptides from EST database by single residue distribution analysis
    • S. Kozlov, and E. Grishin The mining of toxin-like polypeptides from EST database by single residue distribution analysis BMC Genomics 12 2011 88
    • (2011) BMC Genomics , vol.12 , pp. 88
    • Kozlov, S.1    Grishin, E.2
  • 27
    • 45949109669 scopus 로고    scopus 로고
    • MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences
    • DOI 10.1093/bib/bbn017, Special Issue: Critical Technologies for Bioinformatics
    • S. Kumar, M. Nei, J. Dudley, and K. Tamura MEGA: a biologist-centric software for evolutionary analysis of DNA and protein sequences Brief Bioinform 9 2008 299 306 (Pubitemid 351890826)
    • (2008) Briefings in Bioinformatics , vol.9 , Issue.4 , pp. 299-306
    • Kumar, S.1    Nei, M.2    Dudley, J.3    Tamura, K.4
  • 28
    • 0018873523 scopus 로고
    • Protein inhibitors of proteinases
    • J.M. Laskowski, and I. Kato Protein inhibitors of proteinases Annu Rev Biochem 49 1980 593 626
    • (1980) Annu Rev Biochem , vol.49 , pp. 593-626
    • Laskowski, J.M.1    Kato, I.2
  • 30
    • 0040020321 scopus 로고    scopus 로고
    • Equistatin, a new inhibitor of cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain
    • B. Lenarcic, A. Ritonja, B. Strukelj, B. Turk, V. Turk, and Equistatin a new inhibitor of cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain J Biol Chem 272 1997 13899 13903 (Pubitemid 27224832)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.21 , pp. 13899-13903
    • Lenarcic, B.1    Ritonja, A.2    Strukelj, B.3    Turk, B.4    Turk, V.5
  • 31
    • 70349305115 scopus 로고    scopus 로고
    • Identification of novel I-superfamily conopeptides from several clades of Conus species found in the South China Sea
    • Z. Liu, N. Xu, J. Hu, C. Zhao, Z. Yu, and Q. Dai Identification of novel I-superfamily conopeptides from several clades of Conus species found in the South China Sea Peptides 30 2009 1782 1787
    • (2009) Peptides , vol.30 , pp. 1782-1787
    • Liu, Z.1    Xu, N.2    Hu, J.3    Zhao, C.4    Yu, Z.5    Dai, Q.6
  • 32
    • 0037977732 scopus 로고    scopus 로고
    • Amplification of cDNA ends using PCR suppression effect and step-out PCR
    • M.V. Matz, N.O. Alieva, A. Chenchik, and S. Lukyanov Amplification of cDNA ends using PCR suppression effect and step-out PCR Methods Mol Biol 221 2003 41 49
    • (2003) Methods Mol Biol , vol.221 , pp. 41-49
    • Matz, M.V.1    Alieva, N.O.2    Chenchik, A.3    Lukyanov, S.4
  • 33
    • 0018825666 scopus 로고
    • Isolation of proteinase inhibitory, toxic and hemolytic polypeptides from a sea anemone. Stoichactis sp
    • D. Mebs, and E. Gebauer Isolation of proteinase inhibitory, toxic and hemolytic polypeptides from the sea anemone Stoichactis sp. Toxicon 18 1980 97 106 (Pubitemid 10100701)
    • (1980) Toxicon , vol.18 , Issue.1 , pp. 97-106
    • Mebs, D.1    Gebauer, E.2
  • 35
    • 0345917643 scopus 로고    scopus 로고
    • Amino acid sequence and biological activities of another Kunitz-type protease inhibitor from the sea anemone Anthopleura aff. xanthogrammica
    • S. Minagawa, M. Ishida, K. Shimakura, Y. Nagashima, and K. Shiomi Amino acid sequence and biological activities of another Kunitz-type protease inhibitor from the sea anemone Anthopleura aff. xanthogrammica Fish Sci 64 1998 157 161
    • (1998) Fish Sci , vol.64 , pp. 157-161
    • Minagawa, S.1    Ishida, M.2    Shimakura, K.3    Nagashima, Y.4    Shiomi, K.5
  • 37
    • 77958474950 scopus 로고    scopus 로고
    • Actinoporins from the sea anemones, tropical Radianthus macrodactylus and northern Oulactis orientalis: Comparative analysis of structure-function relationships
    • M. Monastyrnaya, E. Leychenko, M. Isaeva, G. Likhatskaya, E. Zelepuga, and E. Kostina Actinoporins from the sea anemones, tropical Radianthus macrodactylus and northern Oulactis orientalis: Comparative analysis of structure-function relationships Toxicon 56 2010 1299 1314
    • (2010) Toxicon , vol.56 , pp. 1299-1314
    • Monastyrnaya, M.1    Leychenko, E.2    Isaeva, M.3    Likhatskaya, G.4    Zelepuga, E.5    Kostina, E.6
  • 38
    • 40849126683 scopus 로고    scopus 로고
    • Concerted evolution of sea anemone neurotoxin genes is revealed through analysis of the Nematostella vectensis genome
    • DOI 10.1093/molbev/msn021
    • Y. Moran, H. Weinberger, J.C. Sullivan, A.M. Reitzel, J.R. Finnerty, and M. Gurevitz Concerted evolution of sea anemone neurotoxin genes is revealed through analysis of the Nematostella vectensis genome Mol Biol Evol 25 2008 737 747 (Pubitemid 351398330)
    • (2008) Molecular Biology and Evolution , vol.25 , Issue.4 , pp. 737-747
    • Moran, Y.1    Weinberger, H.2    Sullivan, J.C.3    Reitzel, A.M.4    Finnerty, J.R.5    Gurevitz, M.6
  • 39
    • 70350374052 scopus 로고    scopus 로고
    • Sea anemone toxins affecting voltage-gated sodium channels-molecular and evolutionary features
    • Y. Moran, D. Gordon, and M. Gurevitz Sea anemone toxins affecting voltage-gated sodium channels-molecular and evolutionary features Toxicon 54 2009 1089 1101
    • (2009) Toxicon , vol.54 , pp. 1089-1101
    • Moran, Y.1    Gordon, D.2    Gurevitz, M.3
  • 41
    • 0028864511 scopus 로고
    • Combinatorial peptide libraries in drug design: Lessons from venomous cone snails
    • B.M. Olivera, D.R. Hillyard, M. Marsh, and D. Yoshikami Combinatorial peptide libraries in drug design: lessons from venomous cone snails Trends Biotechnol 13 1995 422 426
    • (1995) Trends Biotechnol , vol.13 , pp. 422-426
    • Olivera, B.M.1    Hillyard, D.R.2    Marsh, M.3    Yoshikami, D.4
  • 44
    • 48449097801 scopus 로고    scopus 로고
    • WebPIPSA: A web server for the comparison of protein interaction properties
    • S. Richter, A. Wenzel, M. Stein, R.R. Gabdoulline, and R.C. Wade webPIPSA: a web server for the comparison of protein interaction properties Nucleic Acid Res 36 2008 276 280
    • (2008) Nucleic Acid Res , vol.36 , pp. 276-280
    • Richter, S.1    Wenzel, A.2    Stein, M.3    Gabdoulline, R.R.4    Wade, R.C.5
  • 45
    • 0037205399 scopus 로고    scopus 로고
    • Substrate recognition drives the evolution of serine proteases
    • DOI 10.1074/jbc.C200132200
    • T. Rose, and E. Di Cera Substrate recognition drives the evolution of serine proteases J Biol Chem 277 2002 19243 19246 (Pubitemid 34967426)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.22 , pp. 19243-19246
    • Rose, T.1    Di Cera, E.2
  • 47
    • 70350400621 scopus 로고    scopus 로고
    • Novel peptide toxins recently isolated from sea anemones
    • K. Shiomi Novel peptide toxins recently isolated from sea anemones Toxicon 54 2009 1112 1118
    • (2009) Toxicon , vol.54 , pp. 1112-1118
    • Shiomi, K.1
  • 49
    • 35148879562 scopus 로고    scopus 로고
    • A serine protease inhibitor from the anemone Radianthus macrodactylus: Isolation and physicochemical characteristics
    • I.N. Sokotun, E.V. Leichenko, T.I. Vakorina, A.A. Es'kov, A.P. Il'ina, and M.M. Monastyrnaia A serine protease inhibitor from the anemone Radianthus macrodactylus: isolation and physicochemical characteristics Bioorg Khim 33 2007 448 455
    • (2007) Bioorg Khim , vol.33 , pp. 448-455
    • Sokotun, I.N.1    Leichenko, E.V.2    Vakorina, T.I.3    Es'Kov, A.A.4    Il'Ina, A.P.5    Monastyrnaia, M.M.6
  • 50
    • 11144319833 scopus 로고    scopus 로고
    • Were arachnids the first to use combinatorial peptide libraries?
    • DOI 10.1016/j.peptides.2004.07.016, PII S0196978104004723, Invertebrate Neuropeptides V
    • B.L. Sollod, D. Wilson, O. Zhaxybayeva, J.P. Gogarten, R. Drinkwater, and G.F. King Were arachnids the first to use combinatorial peptide libraries? Peptides 26 2005 131 139 (Pubitemid 40038886)
    • (2005) Peptides , vol.26 , Issue.1 , pp. 131-139
    • Sollod, B.L.1    Wilson, D.2    Zhaxybayeva, O.3    Gogarten, J.P.4    Drinkwater, R.5    King, G.F.6
  • 52
    • 77952051544 scopus 로고    scopus 로고
    • Molecular diversification of peptide toxins from the tarantula Haplopelma hainanum (Ornithoctonus hainana) venom based on transcriptomic, peptidomic, and genomic analyses
    • X. Tang, Y. Zhang, W. Hu, D. Xu, H. Tao, and X. Yang Molecular diversification of peptide toxins from the tarantula Haplopelma hainanum (Ornithoctonus hainana) venom based on transcriptomic, peptidomic, and genomic analyses J Proteome Res 9 2010 2550 2564
    • (2010) J Proteome Res , vol.9 , pp. 2550-2564
    • Tang, X.1    Zhang, Y.2    Hu, W.3    Xu, D.4    Tao, H.5    Yang, X.6
  • 53
    • 0023433076 scopus 로고
    • The covalent structure of the elastase inhibitor from Anemonia sulcata - A non-classical Kazal-type protein
    • H. Tschesche, H. Kolkenbrock, and W. Bode The covalent structure of the elastase inhibitor from Anemonia sulcata - a non-classical Kazal-type protein Biol Chem Hoppe Seyler 368 1987 1297 1304
    • (1987) Biol Chem Hoppe Seyler , vol.368 , pp. 1297-1304
    • Tschesche, H.1    Kolkenbrock, H.2    Bode, W.3
  • 54
    • 77958508102 scopus 로고    scopus 로고
    • Molecular characterization on the genome structure of hemolysin toxin isoforms isolated from sea anemone Actineria villosa and Phyllodiscus semoni
    • G. Uechi, H. Toma, T. Arakawa, and Y. Sato Molecular characterization on the genome structure of hemolysin toxin isoforms isolated from sea anemone Actineria villosa and Phyllodiscus semoni Toxicon 56 2010 1470 1476
    • (2010) Toxicon , vol.56 , pp. 1470-1476
    • Uechi, G.1    Toma, H.2    Arakawa, T.3    Sato, Y.4
  • 55
    • 44649084221 scopus 로고    scopus 로고
    • A multigene family of Heteractis magnificalysins (HMgs)
    • Y. Wang, L.L. Yap, K.L. Chua, and H.E. Khoo A multigene family of Heteractis magnificalysins (HMgs) Toxicon 51 2008 1374 1382
    • (2008) Toxicon , vol.51 , pp. 1374-1382
    • Wang, Y.1    Yap, L.L.2    Chua, K.L.3    Khoo, H.E.4
  • 56
    • 0000858538 scopus 로고
    • The broad-specificity proteinase inhibitor 5 II from the sea anemone Anemonia sulcata
    • G. Wunderer, W. Machleidt, and H. Fritz The broad-specificity proteinase inhibitor 5 II from the sea anemone Anemonia sulcata Methods Enzymol 80 1981 816 820
    • (1981) Methods Enzymol , vol.80 , pp. 816-820
    • Wunderer, G.1    MacHleidt, W.2    Fritz, H.3
  • 57
    • 54849414437 scopus 로고    scopus 로고
    • Discovery of a distinct superfamily of Kunitz-type toxin (KTT) from Tarantulas
    • C.H. Yuan, Q.Y. He, K. Peng, J.B. Diao, L.P. Jiang, and X. Tang Discovery of a distinct superfamily of Kunitz-type toxin (KTT) from Tarantulas PLoS One 3 2008 e3414
    • (2008) PLoS One , vol.3 , pp. 3414
    • Yuan, C.H.1    He, Q.Y.2    Peng, K.3    Diao, J.B.4    Jiang, L.P.5    Tang, X.6
  • 58
    • 0038643710 scopus 로고    scopus 로고
    • Adaptive evolution in the snake venom Kunitz/BPTI protein family
    • DOI 10.1016/S0014-5793(03)00693-8
    • V. Zupunski, D. Kordis, and F. Gubensek Adaptive evolution in the snake venom Kunitz/BPTI protein family FEBS Lett 547 2003 131 136 (Pubitemid 36829392)
    • (2003) FEBS Letters , vol.547 , Issue.1-3 , pp. 131-136
    • Zupunski, V.1    Kordis, D.2    Gubensek, F.3


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