메뉴 건너뛰기




Volumn 8, Issue 1, 2012, Pages

In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein

Author keywords

Cytosine methylation; Demethylating agents; Genistein; RNA directed DNA methylation; Transcriptional gene silencing

Indexed keywords

ARABIDOPSIS; NICOTIANA BENTHAMIANA; PETUNIA;

EID: 84858302041     PISSN: None     EISSN: 17464811     Source Type: Journal    
DOI: 10.1186/1746-4811-8-10     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 77952355762 scopus 로고    scopus 로고
    • Genome-wide evolutionary analysis of eukaryotic DNA methylation
    • 10.1126/science.1186366, 20395474
    • Zemach A, McDaniel IE, Silva P, Zilberman D. Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science 2010, 328:916-919. 10.1126/science.1186366, 20395474.
    • (2010) Science , vol.328 , pp. 916-919
    • Zemach, A.1    McDaniel, I.E.2    Silva, P.3    Zilberman, D.4
  • 2
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • 10.1101/gad.947102, 11782440
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002, 16:6-21. 10.1101/gad.947102, 11782440.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 4
    • 0037418586 scopus 로고    scopus 로고
    • Role of CG and non-CG methylation in immobilization of transposons in Arabidopsis
    • 10.1016/S0960-9822(03)00106-4, 12620192
    • Kato M, Miura A, Bender J, Jacobsen SE, Kakutani T. Role of CG and non-CG methylation in immobilization of transposons in Arabidopsis. Curr Biol 2003, 13:421-426. 10.1016/S0960-9822(03)00106-4, 12620192.
    • (2003) Curr Biol , vol.13 , pp. 421-426
    • Kato, M.1    Miura, A.2    Bender, J.3    Jacobsen, S.E.4    Kakutani, T.5
  • 5
    • 0035837378 scopus 로고    scopus 로고
    • Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis
    • 10.1038/35075612, 11346800
    • Miura A, Yonebayashi S, Watanabe K, Toyama T, Shimada H, Kakutani T. Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis. Nature 2001, 411:212-214. 10.1038/35075612, 11346800.
    • (2001) Nature , vol.411 , pp. 212-214
    • Miura, A.1    Yonebayashi, S.2    Watanabe, K.3    Toyama, T.4    Shimada, H.5    Kakutani, T.6
  • 6
    • 0035282119 scopus 로고    scopus 로고
    • Robertson's Mutator transposons in A. thaliana are regulated by the chromatin-remodeling gene Decrease in DNA Methylation (DDM1)
    • 10.1101/gad.193701, 312647, 11238379
    • Singer T, Yordan C, Martienssen RA. Robertson's Mutator transposons in A. thaliana are regulated by the chromatin-remodeling gene Decrease in DNA Methylation (DDM1). Genes Dev 2001, 15:591-602. 10.1101/gad.193701, 312647, 11238379.
    • (2001) Genes Dev , vol.15 , pp. 591-602
    • Singer, T.1    Yordan, C.2    Martienssen, R.A.3
  • 7
    • 70349276670 scopus 로고    scopus 로고
    • Bursts of retrotransposition reproduced in Arabidopsis
    • 10.1038/nature08351, 19734880
    • Tsukahara S, Kobayashi A, Kawabe A, Mathieu O, Miura A, Kakutani T. Bursts of retrotransposition reproduced in Arabidopsis. Nature 2009, 461:423-426. 10.1038/nature08351, 19734880.
    • (2009) Nature , vol.461 , pp. 423-426
    • Tsukahara, S.1    Kobayashi, A.2    Kawabe, A.3    Mathieu, O.4    Miura, A.5    Kakutani, T.6
  • 8
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • 10.1146/annurev.biochem.74.010904.153721, 15952895
    • Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem 2005, 74:481-514. 10.1146/annurev.biochem.74.010904.153721, 15952895.
    • (2005) Annu Rev Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 9
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: provocative insights from epigenomics
    • Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 2008, 9:465-476.
    • (2008) Nat Rev Genet , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 10
    • 33845880624 scopus 로고    scopus 로고
    • Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription
    • 10.1038/ng1929, 17128275
    • Zilberman D, Gehring M, Tran RK, Ballinger T, Henikoff S. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet 2007, 39:61-69. 10.1038/ng1929, 17128275.
    • (2007) Nat Genet , vol.39 , pp. 61-69
    • Zilberman, D.1    Gehring, M.2    Tran, R.K.3    Ballinger, T.4    Henikoff, S.5
  • 11
    • 65249148019 scopus 로고    scopus 로고
    • RNA-mediated chromatin-based silencing in plants
    • 10.1016/j.ceb.2009.01.025, 19243928
    • Matzke M, Kanno T, Daxinger L, Huettel B, Matzke AJ. RNA-mediated chromatin-based silencing in plants. Curr Opin Cell Biol 2009, 21:367-376. 10.1016/j.ceb.2009.01.025, 19243928.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 367-376
    • Matzke, M.1    Kanno, T.2    Daxinger, L.3    Huettel, B.4    Matzke, A.J.5
  • 12
    • 17744364327 scopus 로고    scopus 로고
    • Gardening the genome: DNA methylation in Arabidopsis thaliana
    • Chan SW, Henderson IR, Jacobsen SE. Gardening the genome: DNA methylation in Arabidopsis thaliana. Nat Rev Genet 2005, 6:351-360.
    • (2005) Nat Rev Genet , vol.6 , pp. 351-360
    • Chan, S.W.1    Henderson, I.R.2    Jacobsen, S.E.3
  • 13
    • 78650586854 scopus 로고    scopus 로고
    • Virus-mediated efficient induction of epigenetic modifications of endogenous genes with phenotypic changes in plants
    • 10.1111/j.1365-313X.2010.04401.x, 21175898
    • Kanazawa A, Inaba J, Shimura H, Otagaki S, Tsukahara S, Matsuzawa A, Kim BM, Goto K, Masuta C. Virus-mediated efficient induction of epigenetic modifications of endogenous genes with phenotypic changes in plants. Plant J 2011, 65:156-168. 10.1111/j.1365-313X.2010.04401.x, 21175898.
    • (2011) Plant J , vol.65 , pp. 156-168
    • Kanazawa, A.1    Inaba, J.2    Shimura, H.3    Otagaki, S.4    Tsukahara, S.5    Matsuzawa, A.6    Kim, B.M.7    Goto, K.8    Masuta, C.9
  • 14
    • 79958705395 scopus 로고    scopus 로고
    • RNA-mediated epigenetic modifications of an endogenous gene targeted by a viral vector: a potent gene silencing system to produce a plant that does not carry a transgene but has altered traits
    • 10.4161/psb.6.8.16046, 3260699, 21772121
    • Kanazawa A, Inaba J, Kasai M, Shimura H, Masuta C. RNA-mediated epigenetic modifications of an endogenous gene targeted by a viral vector: a potent gene silencing system to produce a plant that does not carry a transgene but has altered traits. Plant Signal Behav 2011, 6:1090-1093. 10.4161/psb.6.8.16046, 3260699, 21772121.
    • (2011) Plant Signal Behav , vol.6 , pp. 1090-1093
    • Kanazawa, A.1    Inaba, J.2    Kasai, M.3    Shimura, H.4    Masuta, C.5
  • 15
    • 79955086529 scopus 로고    scopus 로고
    • Selected aspects of transgenerational epigenetic inheritance and resetting in plants
    • 10.1016/j.pbi.2011.01.002, 21333585
    • Paszkowski J, Grossniklaus U. Selected aspects of transgenerational epigenetic inheritance and resetting in plants. Curr Opin Plant Biol 2011, 14:195-203. 10.1016/j.pbi.2011.01.002, 21333585.
    • (2011) Curr Opin Plant Biol , vol.14 , pp. 195-203
    • Paszkowski, J.1    Grossniklaus, U.2
  • 16
    • 34547751795 scopus 로고    scopus 로고
    • Epigenetic inheritance in rice plants
    • 10.1093/aob/mcm110, 2735323, 17576658
    • Akimoto K, Katakami H, Kim HJ, Ogawa E, Sano CM, Wada Y, Sano H. Epigenetic inheritance in rice plants. Ann Bot 2007, 100:205-217. 10.1093/aob/mcm110, 2735323, 17576658.
    • (2007) Ann Bot , vol.100 , pp. 205-217
    • Akimoto, K.1    Katakami, H.2    Kim, H.J.3    Ogawa, E.4    Sano, C.M.5    Wada, Y.6    Sano, H.7
  • 17
    • 65249186659 scopus 로고    scopus 로고
    • Compromised stability of DNA methylation and transposon immobilization in mosaic Arabidopsis epigenomes
    • 10.1101/gad.524609, 2675864, 19390088
    • Reinders J, Wulff BB, Mirouze M, Marí-Ordóñez A, Dapp M, Rozhon W, Bucher E, Theiler G, Paszkowski J. Compromised stability of DNA methylation and transposon immobilization in mosaic Arabidopsis epigenomes. Genes Dev 2009, 23:939-950. 10.1101/gad.524609, 2675864, 19390088.
    • (2009) Genes Dev , vol.23 , pp. 939-950
    • Reinders, J.1    Wulff, B.B.2    Mirouze, M.3    Marí-Ordóñez, A.4    Dapp, M.5    Rozhon, W.6    Bucher, E.7    Theiler, G.8    Paszkowski, J.9
  • 18
    • 77949864217 scopus 로고    scopus 로고
    • Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins
    • 10.1371/journal.pone.0009514, 2831073, 20209086
    • Boyko A, Blevins T, Yao Y, Golubov A, Bilichak A, Ilnytskyy Y, Hollunder J, Hollander J, Meins F, Kovalchuk I. Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins. PLoS One 2010, 5:e9514. 10.1371/journal.pone.0009514, 2831073, 20209086.
    • (2010) PLoS One , vol.5
    • Boyko, A.1    Blevins, T.2    Yao, Y.3    Golubov, A.4    Bilichak, A.5    Ilnytskyy, Y.6    Hollunder, J.7    Hollander, J.8    Meins, F.9    Kovalchuk, I.10
  • 20
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • 10.1016/0092-8674(80)90237-8, 6156004
    • Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 1980, 20:85-93. 10.1016/0092-8674(80)90237-8, 6156004.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 22
    • 58849132900 scopus 로고    scopus 로고
    • Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine
    • 10.1111/j.1365-313X.2008.03699.x, 2667684, 18826433
    • Baubec T, Pecinka A, Rozhon W, Mittelsten Scheid O. Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine. Plant J 2009, 57:542-554. 10.1111/j.1365-313X.2008.03699.x, 2667684, 18826433.
    • (2009) Plant J , vol.57 , pp. 542-554
    • Baubec, T.1    Pecinka, A.2    Rozhon, W.3    Mittelsten Scheid, O.4
  • 23
    • 28844497663 scopus 로고    scopus 로고
    • Procainamide is a specific inhibitor of DNA methyltransferase 1
    • 10.1074/jbc.M505593200, 1989680, 16230360
    • Lee BH, Yegnasubramanian S, Lin X, Nelson WG. Procainamide is a specific inhibitor of DNA methyltransferase 1. J Biol Chem 2005, 280:40749-40756. 10.1074/jbc.M505593200, 1989680, 16230360.
    • (2005) J Biol Chem , vol.280 , pp. 40749-40756
    • Lee, B.H.1    Yegnasubramanian, S.2    Lin, X.3    Nelson, W.G.4
  • 24
    • 0032482974 scopus 로고    scopus 로고
    • Trichostatin A causes selective loss of DNA methylation in Neurospora
    • 10.1073/pnas.95.16.9430, 21355, 9689097
    • Selker EU. Trichostatin A causes selective loss of DNA methylation in Neurospora. Proc Natl Acad Sci USA 1998, 95:9430-9435. 10.1073/pnas.95.16.9430, 21355, 9689097.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9430-9435
    • Selker, E.U.1
  • 25
    • 1542285163 scopus 로고    scopus 로고
    • A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance
    • 10.1016/S1097-2765(04)00064-4, 14992728
    • Lawrence RJ, Earley K, Pontes O, Silva M, Chen ZJ, Neves N, Viegas W, Pikaard CS. A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance. Mol Cell 2004, 13:599-609. 10.1016/S1097-2765(04)00064-4, 14992728.
    • (2004) Mol Cell , vol.13 , pp. 599-609
    • Lawrence, R.J.1    Earley, K.2    Pontes, O.3    Silva, M.4    Chen, Z.J.5    Neves, N.6    Viegas, W.7    Pikaard, C.S.8
  • 26
    • 34250307172 scopus 로고    scopus 로고
    • Epigenetic inactivation of chalcone synthase-A transgene transcription in petunia leads to a reversion of the post-transcriptional gene silencing phenotype
    • 10.1093/pcp/pcm028, 17317685
    • Kanazawa A, O'Dell M, Hellens RP. Epigenetic inactivation of chalcone synthase-A transgene transcription in petunia leads to a reversion of the post-transcriptional gene silencing phenotype. Plant Cell Physiol 2007, 48:638-647. 10.1093/pcp/pcm028, 17317685.
    • (2007) Plant Cell Physiol , vol.48 , pp. 638-647
    • Kanazawa, A.1    O'Dell, M.2    Hellens, R.P.3
  • 27
    • 33845678142 scopus 로고    scopus 로고
    • Trichostatin A down-regulates DNA methyltransferase 1 in Jurkat T cells
    • 10.1016/j.canlet.2006.03.010, 16624484
    • Januchowski R, Dabrowski M, Ofori H, Jagodzinski PP. Trichostatin A down-regulates DNA methyltransferase 1 in Jurkat T cells. Cancer Lett 2007, 246:313-317. 10.1016/j.canlet.2006.03.010, 16624484.
    • (2007) Cancer Lett , vol.246 , pp. 313-317
    • Januchowski, R.1    Dabrowski, M.2    Ofori, H.3    Jagodzinski, P.P.4
  • 28
    • 27644597195 scopus 로고    scopus 로고
    • Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine
    • 10.1158/1535-7163.MCT-05-0172, 16227400
    • Chuang JC, Yoo CB, Kwan JM, Li TW, Liang G, Yang AS, Jones PA. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Mol Cancer Ther 2005, 4:1515-1520. 10.1158/1535-7163.MCT-05-0172, 16227400.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1515-1520
    • Chuang, J.C.1    Yoo, C.B.2    Kwan, J.M.3    Li, T.W.4    Liang, G.5    Yang, A.S.6    Jones, P.A.7
  • 29
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang CS. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003, 63:7563-7570.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 30
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M, Chen D, Yang CS. Dietary polyphenols may affect DNA methylation. J Nutr 2007, 137:223S-228S.
    • (2007) J Nutr , vol.137
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 31
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • 10.1158/1078-0432.CCR-05-0406, 16203797
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 2005, 11:7033-7041. 10.1158/1078-0432.CCR-05-0406, 16203797.
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 32
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • 10.1002/em.20363, 18181168
    • King-Batoon A, Leszczynska JM, Klein CB. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen 2008, 49:36-45. 10.1002/em.20363, 18181168.
    • (2008) Environ Mol Mutagen , vol.49 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 33
    • 31544441371 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
    • 10.1093/carcin/bgi206, 16081510
    • Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 2006, 27:269-277. 10.1093/carcin/bgi206, 16081510.
    • (2006) Carcinogenesis , vol.27 , pp. 269-277
    • Lee, W.J.1    Zhu, B.T.2
  • 35
    • 25144507259 scopus 로고    scopus 로고
    • Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
    • 10.1124/mol.104.008367, 16037419
    • Lee WJ, Shim JY, Zhu BT. Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 2005, 68:1018-1030. 10.1124/mol.104.008367, 16037419.
    • (2005) Mol Pharmacol , vol.68 , pp. 1018-1030
    • Lee, W.J.1    Shim, J.Y.2    Zhu, B.T.3
  • 36
    • 1842584266 scopus 로고    scopus 로고
    • Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies
    • 10.1016/j.toxlet.2003.06.001, 15068824
    • Park OJ, Surh YJ. Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies. Toxicol Lett 2004, 150:43-56. 10.1016/j.toxlet.2003.06.001, 15068824.
    • (2004) Toxicol Lett , vol.150 , pp. 43-56
    • Park, O.J.1    Surh, Y.J.2
  • 37
    • 79958747794 scopus 로고    scopus 로고
    • Size and positional effects of promoter RNA segments on virus-induced RNA-directed DNA methylation and transcriptional gene silencing
    • 10.4161/epi.6.6.16214, 21610318
    • Otagaki S, Kawai M, Masuta C, Kanazawa A. Size and positional effects of promoter RNA segments on virus-induced RNA-directed DNA methylation and transcriptional gene silencing. Epigenetics 2011, 6:681-691. 10.4161/epi.6.6.16214, 21610318.
    • (2011) Epigenetics , vol.6 , pp. 681-691
    • Otagaki, S.1    Kawai, M.2    Masuta, C.3    Kanazawa, A.4
  • 38
    • 0017801980 scopus 로고
    • Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine
    • 10.1021/jm00200a012, 74412
    • Beisler JA. Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine. J Med Chem 1978, 21:204-208. 10.1021/jm00200a012, 74412.
    • (1978) J Med Chem , vol.21 , pp. 204-208
    • Beisler, J.A.1
  • 39
    • 23844494476 scopus 로고    scopus 로고
    • Distinct regulation of histone H3 methylation at lysines 27 and 9 by CpG methylation in Arabidopsis
    • 10.1038/sj.emboj.7600743, 1182238, 16001083
    • Mathieu O, Probst AV, Paszkowski J. Distinct regulation of histone H3 methylation at lysines 27 and 9 by CpG methylation in Arabidopsis. EMBO J 2005, 24:2783-2791. 10.1038/sj.emboj.7600743, 1182238, 16001083.
    • (2005) EMBO J , vol.24 , pp. 2783-2791
    • Mathieu, O.1    Probst, A.V.2    Paszkowski, J.3
  • 41
    • 46049103996 scopus 로고    scopus 로고
    • Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
    • 10.1002/ijc.23590, 18431742
    • Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Majid S, Igawa M, Dahiya R. Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. Int J Cancer 2008, 123:552-560. 10.1002/ijc.23590, 18431742.
    • (2008) Int J Cancer , vol.123 , pp. 552-560
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3    Kawamoto, K.4    Hirata, H.5    Tanaka, Y.6    Majid, S.7    Igawa, M.8    Dahiya, R.9
  • 42
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
    • 10.1038/sj.onc.1205699, 12154409
    • Christman JK. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 2002, 21:5483-5495. 10.1038/sj.onc.1205699, 12154409.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 43
    • 22144461094 scopus 로고    scopus 로고
    • Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy
    • 10.4161/cbt.3.11.1308, 15539938
    • Gowher H, Jeltsch A. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther 2004, 3:1062-1068. 10.4161/cbt.3.11.1308, 15539938.
    • (2004) Cancer Biol Ther , vol.3 , pp. 1062-1068
    • Gowher, H.1    Jeltsch, A.2
  • 44
    • 0031001563 scopus 로고    scopus 로고
    • Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase
    • 10.1073/pnas.94.9.4681, 20784, 9114051
    • Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proc Natl Acad Sci USA 1997, 94:4681-4685. 10.1073/pnas.94.9.4681, 20784, 9114051.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4681-4685
    • Jackson-Grusby, L.1    Laird, P.W.2    Magge, S.N.3    Moeller, B.J.4    Jaenisch, R.5
  • 45
    • 43149110168 scopus 로고    scopus 로고
    • Identification and characterization of isoflavonoid specific glycosyltransferase and malonyltransferase from soybean seeds
    • 10.1093/jxb/ern046, 18310083
    • Dhaubhadel S, Farhangkhoee M, Chapman R. Identification and characterization of isoflavonoid specific glycosyltransferase and malonyltransferase from soybean seeds. J Exp Bot 2008, 59:981-994. 10.1093/jxb/ern046, 18310083.
    • (2008) J Exp Bot , vol.59 , pp. 981-994
    • Dhaubhadel, S.1    Farhangkhoee, M.2    Chapman, R.3
  • 46
    • 0033214408 scopus 로고    scopus 로고
    • Flavonoids and isoflavonoids - a gold mine for metabolic engineering
    • 10.1016/S1360-1385(99)01471-5, 10498963
    • Dixon RA, Steele CL. Flavonoids and isoflavonoids - a gold mine for metabolic engineering. Trends Plant Sci 1999, 4:394-400. 10.1016/S1360-1385(99)01471-5, 10498963.
    • (1999) Trends Plant Sci , vol.4 , pp. 394-400
    • Dixon, R.A.1    Steele, C.L.2
  • 47
    • 0034979805 scopus 로고    scopus 로고
    • Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology
    • 10.1104/pp.126.2.485, 1540115, 11402179
    • Winkel-Shirley B. Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. Plant Physiol 2001, 126:485-493. 10.1104/pp.126.2.485, 1540115, 11402179.
    • (2001) Plant Physiol , vol.126 , pp. 485-493
    • Winkel-Shirley, B.1
  • 48
    • 73949104134 scopus 로고    scopus 로고
    • Flavonoids: new roles for old molecules
    • 10.1111/j.1744-7909.2010.00905.x, 20074144
    • Buer CS, Imin N, Djordjevic MA. Flavonoids: new roles for old molecules. J Integr Plant Biol 2010, 52:98-111. 10.1111/j.1744-7909.2010.00905.x, 20074144.
    • (2010) J Integr Plant Biol , vol.52 , pp. 98-111
    • Buer, C.S.1    Imin, N.2    Djordjevic, M.A.3
  • 50
    • 1642450675 scopus 로고    scopus 로고
    • Flavanol binding of nuclei from tree species
    • 10.1007/s00299-003-0705-7, 14595514
    • Feucht W, Treutter D, Polster J. Flavanol binding of nuclei from tree species. Plant Cell Rep 2004, 22:430-436. 10.1007/s00299-003-0705-7, 14595514.
    • (2004) Plant Cell Rep , vol.22 , pp. 430-436
    • Feucht, W.1    Treutter, D.2    Polster, J.3
  • 51
    • 2442543374 scopus 로고    scopus 로고
    • The transparent testa4 mutation prevents flavonoid synthesis and alters auxin transport and the response of Arabidopsis roots to gravity and light
    • 10.1105/tpc.020313, 423209, 15100399
    • Buer CS, Muday GK. The transparent testa4 mutation prevents flavonoid synthesis and alters auxin transport and the response of Arabidopsis roots to gravity and light. Plant Cell 2004, 16:1191-1205. 10.1105/tpc.020313, 423209, 15100399.
    • (2004) Plant Cell , vol.16 , pp. 1191-1205
    • Buer, C.S.1    Muday, G.K.2
  • 52
    • 21244501422 scopus 로고    scopus 로고
    • Nuclear localization of flavonoid enzymes in Arabidopsis
    • 10.1074/jbc.M413506200, 15817473
    • Saslowsky DE, Warek U, Winkel BS. Nuclear localization of flavonoid enzymes in Arabidopsis. J Biol Chem 2005, 280:23735-23740. 10.1074/jbc.M413506200, 15817473.
    • (2005) J Biol Chem , vol.280 , pp. 23735-23740
    • Saslowsky, D.E.1    Warek, U.2    Winkel, B.S.3
  • 53
    • 0033395927 scopus 로고    scopus 로고
    • Anthocyanin-DNA copigmentation complex: mutual protection against oxidative damage
    • Sarma A, Sharma R. Anthocyanin-DNA copigmentation complex: mutual protection against oxidative damage. Phytochemistry 1999, 52:1313-1318.
    • (1999) Phytochemistry , vol.52 , pp. 1313-1318
    • Sarma, A.1    Sharma, R.2
  • 54
    • 0030942554 scopus 로고    scopus 로고
    • RNA-mediated RNA degradation and chalcone synthase A silencing in petunia
    • 10.1016/S0092-8674(00)81930-3, 9118227
    • Metzlaff M, O'Dell M, Cluster PD, Flavell RB. RNA-mediated RNA degradation and chalcone synthase A silencing in petunia. Cell 1997, 88:845-854. 10.1016/S0092-8674(00)81930-3, 9118227.
    • (1997) Cell , vol.88 , pp. 845-854
    • Metzlaff, M.1    O'Dell, M.2    Cluster, P.D.3    Flavell, R.B.4
  • 55
    • 0032962650 scopus 로고    scopus 로고
    • Post-transcriptional gene silencing of chalcone synthase in transgenic petunias, cytosine methylation and epigenetic variation
    • O'Dell M, Metzlaff M, Flavell R. Post-transcriptional gene silencing of chalcone synthase in transgenic petunias, cytosine methylation and epigenetic variation. Plant J 1999, 18:33-42.
    • (1999) Plant J , vol.18 , pp. 33-42
    • O'Dell, M.1    Metzlaff, M.2    Flavell, R.3
  • 56
    • 84855873981 scopus 로고    scopus 로고
    • Coincident sequence-specific RNA degradation of linked transgenes in the plant genome
    • 10.1007/s11103-011-9863-0, 22146813
    • Kasai M, Koseki M, Goto K, Masuta C, Ishii S, Hellens RP, Taneda A, Kanazawa A. Coincident sequence-specific RNA degradation of linked transgenes in the plant genome. Plant Mol Biol 2012, 78:259-273. 10.1007/s11103-011-9863-0, 22146813.
    • (2012) Plant Mol Biol , vol.78 , pp. 259-273
    • Kasai, M.1    Koseki, M.2    Goto, K.3    Masuta, C.4    Ishii, S.5    Hellens, R.P.6    Taneda, A.7    Kanazawa, A.8
  • 57
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • 159885, 12354959
    • Napoli C, Lemieux C, Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 1990, 2:279-289. 159885, 12354959.
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 58
    • 3643145804 scopus 로고    scopus 로고
    • Initiation and maintenance of virus-induced gene silencing
    • 144041, 9634582
    • Ruiz MT, Voinnet O, Baulcombe DC. Initiation and maintenance of virus-induced gene silencing. Plant Cell 1998, 10:937-946. 144041, 9634582.
    • (1998) Plant Cell , vol.10 , pp. 937-946
    • Ruiz, M.T.1    Voinnet, O.2    Baulcombe, D.C.3
  • 59
    • 84982358134 scopus 로고
    • A revised medium for rapid growth and bioassays with tobacco tissue cultures
    • Murashige T, Skoog F. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 1962, 15:473-497.
    • (1962) Physiol Plant , vol.15 , pp. 473-497
    • Murashige, T.1    Skoog, F.2
  • 60
    • 34249673341 scopus 로고    scopus 로고
    • The binding of nuclear factors to the as-1 element in the CaMV 35S promoter is affected by cytosine methylation in vitro
    • 10.1055/s-2006-924633, 17099844
    • Kanazawa A, O''Dell M, Hellens RP. The binding of nuclear factors to the as-1 element in the CaMV 35S promoter is affected by cytosine methylation in vitro. Plant Biol 2007, 9:435-441. 10.1055/s-2006-924633, 17099844.
    • (2007) Plant Biol , vol.9 , pp. 435-441
    • Kanazawa, A.1    O'Dell, M.2    Hellens, R.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.