The role of Helicobacter pylori infection in the web of gastric cancer causation

European Journal of Cancer Prevention

Volumn 21, Issue 2, 2012, Pages 118-125

  Peleteiro, Bárbara ^a,b   La Vecchia, Carlo ^c   Lunet, Nuno ^a,b  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Causality; Helicobacter pylori; Stomach neoplasms

Indexed keywords

CAGA PROTEIN; INTERLEUKIN 1; TUMOR NECROSIS FACTOR ALPHA;

BACTERIAL STRAIN; BACTERIAL VIRULENCE; CANCER CLASSIFICATION; CANCER CONTROL; CANCER DIAGNOSIS; CANCER EPIDEMIOLOGY; CANCER GROWTH; CANCER INCIDENCE; CANCER MORTALITY; CANCER PREVENTION; CANCER RISK; CANCER STAGING; CARCINOGENESIS; CELL HETEROGENEITY; DISEASE ASSOCIATION; DNA POLYMORPHISM; ENVIRONMENTAL EXPOSURE; FOOD INTAKE; FRUIT; GENE CLUSTER; GENETIC ANALYSIS; GENOTYPE; HEALTH STATUS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; PRECANCER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; SALT INTAKE; SMOKING; STOMACH CANCER; TUMOR DIFFERENTIATION; VEGETABLE;

CARCINOMA; CAUSALITY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INCIDENCE; MODELS, BIOLOGICAL; RISK FACTORS; STOMACH NEOPLASMS;

EID: 84858297170     PISSN: 09598278     EISSN: 14735709     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e32834a7f66     Document Type: Review

References (77)

1. Adamu MA, Weck MN, Gao L, Brenner H (2010). Incidence of chronic atrophic gastritis: systematic review and meta-analysis of follow-up studies. Eur J Epidemiol 25:439-448.
2. Almeida R, Silva E, Santos-Silva F, Silberg DG,Wang J, De Bolos C, et al. (2003). Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. J Pathol 199:36-40. (Pubitemid 36054727)
3. Barros R, Peleteiro B, Almeida R, Figueiredo C, Barros H, David L, et al. (2010). Relevance of high virulence Helicobacter pylori strains and futility of CDX2 expression for predicting intestinal metaplasia after eradication of infection. Scand J Gastroenterol 45:828-834.
4. Bertuccio P, Chatenoud L, Levi F, Praud D, Ferlay J, Negri E, et al. (2009). Recent patterns in gastric cancer: a global overview. Int J Cancer 125:666-673.
5. Bornschein J, Selgrad M,Warnecke M, Kuester D,Wex T, Malfertheiner P (2010). H. pylori infection is a key risk factor for proximal gastric cancer. Dig Dis Sci 55:3124-3131.
6. Botterweck AA, Schouten LJ, Volovics A, Dorant E, van Den Brandt PA (2000). Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries. Int J Epidemiol 29:645-654. (Pubitemid 30612230)
7. Brenner H, Arndt V, Stegmaier C, Ziegler H, Rothenbacher D (2004). Is Helicobacter pylori infection a necessary condition for noncardia gastric cancer? Am J Epidemiol 159:252-258. (Pubitemid 38141654)
8. Camargo MC, Mera R, Correa P, Peek RM Jr, Fontham ET, Goodman KJ, et al. (2006). Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev 15:1674-1687. (Pubitemid 44497104)
9. Cavaleiro-Pinto M, Peleteiro B, Lunet N, Barros H (2011). Helicobacter pylori infection and gastric cardia cancer: systematic review and meta-analysis. Cancer Causes Control 22:375-387.
10. Corley DA, Kubo A (2004). Influence of site classification on cancer incidence rates: an analysis of gastric cardia carcinomas. J Natl Cancer Inst 96:1383-1387. (Pubitemid 39406172)
11. Correa P (1992). Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 52:6735-6740.
12. Correa P, Sasano N, Stemmermann GN, Haenszel W (1973). Pathology of gastric carcinoma in Japanese populations: comparisons between Miyagi prefecture, Japan, and Hawaii. J Natl Cancer Inst 51:1449-1459.
13. Correa P, Haenszel W, Cuello C, Tannenbaum S, Archer M (1975). A model for gastric cancer epidemiology. Lancet 2:58-60.
14. Correa P, Fontham ET, Bravo JC, Bravo LE, Ruiz B, Zarama G, et al. (2000). Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy. J Natl Cancer Inst 92:1881-1888. (Pubitemid 32036918)
15. Danesh J (1999). Helicobacter pylori infection and gastric cancer: systematic review of the epidemiological studies. Aliment Pharmacol Ther 13:851-856.
16. Derakhshan MH, Malekzadeh R,Watabe H, Yazdanbod A, Fyfe V, Kazemi A, et al. (2008). Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gastric cardia cancer. Gut 57:298-305. (Pubitemid 351288093)
17. Eda A, Osawa H, Yanaka I, Satoh K, Mutoh H, Kihira K, et al. (2002). Expression of homeobox gene CDX2 precedes that of CDX1 during the progression of intestinal metaplasia. J Gastroenterol 37:94-100. (Pubitemid 34223741)
18. Ekstrom AM, Signorello LB, Hansson LE, Bergstrom R, Lindgren A, Nyren O (1999). Evaluating gastric cancer misclassification: a potential explanation for the rise in cardia cancer incidence. J Natl Cancer Inst 91:786-790. (Pubitemid 29239058)
19. Ekstrom AM, Held M, Hansson LE, Engstrand L, Nyren O (2001). Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection. Gastroenterology 121:784-791. (Pubitemid 32959388)
20. Eslick GD, Lim LL, Byles JE, Xia HH, Talley NJ (1999). Association of Helicobacter pylori infection with gastric carcinoma: a meta-analysis. Am J Gastroenterol 94:2373-2379. (Pubitemid 29420659)
21. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2010). GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer. Available from: http://globocan.iarc.fr. [Accessed 26 May 2011].
22. Forman D, Webb P, Parsonnet J (1994). H. pylori and gastric cancer. Lancet 343:243-244.
23. Fuccio L, Zagari RM, Minardi ME, Bazzoli F (2007). Systematic review: Helicobacter pylori eradication for the prevention of gastric cancer. Aliment Pharmacol Ther 25:133-141. (Pubitemid 46046370)
24. Fuccio L, Zagari RM, Eusebi LH, Laterza L, Cennamo V, Ceroni L, et al. (2009). Meta-analysis: can Helicobacter pylori eradication treatment reduce the risk for gastric cancer? Ann Intern Med 151:121-128.
25. Gao L, Weck MN, Nieters A, Brenner H (2009). Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: enhanced elimination of the infection during disease progression? Eur J Cancer 45:2860-2866.
26. Gonzalez CA, Sala N, Capella G (2002). Genetic susceptibility and gastric cancer risk. Int J Cancer 100:249-260. (Pubitemid 34728981)
27. Gorouhi F, Islami F, Bahrami H, Kamangar F (2008). Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis. Br J Cancer 98:1443-1451. (Pubitemid 351543569)
28. Guo RJ, Suh ER, Lynch JP (2004). The role of Cdx proteins in intestinal development and cancer. Cancer Biol Ther 3:593-601.
29. Hansen S, Vollset SE, Derakhshan MH, Fyfe V, Melby KK, Aase S, et al. (2007). Two distinct aetiologies of cardia cancer; evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status. Gut 56:918-925. (Pubitemid 46999074)
30. Helicobacter and Cancer Collaborative Group (2001). Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut 49:347-353.
31. Holcombe C (1992). Helicobacter pylori: the African enigma. Gut 33:429-431.
32. Howson CP, Hiyama T, Wynder EL (1986). The decline in gastric cancer: epidemiology of an unplanned triumph. Epidemiol Rev 8:1-27.
33. Hsu PI, Lai KH, Hsu PN, Lo GH, Yu HC, Chen WC, et al. (2007). Helicobacter pylori infection and the risk of gastric malignancy. Am J Gastroenterol 102:725-730.
34. Huang JQ, Sridhar S, Chen Y, Hunt RH (1998). Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology 114:1169-1179. (Pubitemid 28243902)
35. Huang JQ, Zheng GF, Sumanac K, Irvine EJ, Hunt RH (2003). Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology 125:1636-1644. (Pubitemid 37500427)
36. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. (1994). Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum 61:1-241.
37. Ito M, Takata S, Tatsugami M, Wada Y, Imagawa S, Matsumoto Y, et al. (2009). Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review. J Gastroenterol 44:365-371.
38. Kamangar F, Cheng C, Abnet CC, Rabkin CS (2006). Interleukin-1B polymorphisms and gastric cancer risk - a meta-analysis. Cancer Epidemiol Biomarkers Prev 15:1920-1928. (Pubitemid 44664269)
39. Kidd M, Louw JA, Marks IN (1999). Helicobacter pylori in Africa: observations on an 'enigma within an enigma'. J Gastroenterol Hepatol 14:851-858. (Pubitemid 29459793)
40. Kokkola A, Kosunen TU, Puolakkainen P, Sipponen P, Harkonen M, Laxen F, et al. (2003). Spontaneous disappearance of Helicobacter pylori antibodies in patients with advanced atrophic corpus gastritis. APMIS 111:619-624. (Pubitemid 37130032)
41. Ladeiras-Lopes R, Pereira AK, Nogueira A, Pinheiro-Torres T, Pinto I, Santos-Pereira R, et al. (2008). Smoking and gastric cancer: systematic review and meta-analysis of cohort studies. Cancer Causes Control 19:689-701.
42. Larsson SC, Orsini N, Wolk A (2006). Processed meat consumption and stomach cancer risk: a meta-analysis. J Natl Cancer Inst 98:1078-1087. (Pubitemid 44288156)
43. Lauren P (1965). The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64:31-49.
44. Laurén PA, Nevalainen TJ (1993). Epidemiology of intestinal and diffuse types of gastric carcinoma. A time-trend study in Finland with comparison between studies from high- and low-risk areas. Cancer 71:2926-2933. (Pubitemid 23145518)
45. Loh M, Koh KX, Yeo BH, Song CM, Chia KS, Zhu F, et al. (2009). Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race. Eur J Cancer 45:2562-2568.
46. Louw JA, Kidd MS, Kummer AF, Taylor K, Kotze U, Hanslo D (2001). The relationship between Helicobacter pylori infection, the virulence genotypes of the infecting strain and gastric cancer in the African setting. Helicobacter 6:268-273. (Pubitemid 34015007)
47. Lunet N, Barros H (2003). Helicobacter pylori infection and gastric cancer: facing the enigmas. Int J Cancer 106:953-960. (Pubitemid 37071677)
48. Lunet N, Lacerda-Vieira A, Barros H (2005). Fruit and vegetables consumption and gastric cancer: a systematic review and meta-analysis of cohort studies. Nutr Cancer 53:1-10. (Pubitemid 43068548)
49. Lunet N, Valbuena C, Vieira AL, Lopes C, David L, Carneiro F, et al. (2007). Fruit and vegetable consumption and gastric cancer by location and histological type: case-control and meta-analysis. Eur J Cancer Prev 16:312-327. (Pubitemid 47165297)
50. Marshall BJ, Warren JR (1984). Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1:1311-1315.
51. Mera R, Fontham ET, Bravo LE, Bravo JC, Piazuelo MB, Camargo MC, et al. (2005). Long term follow up of patients treated for Helicobacter pylori infection. Gut 54:1536-1540. (Pubitemid 41531767)
52. Mitchell HM, Ally R, Wadee A, Wiseman M, Segal I (2002). Major differences in the IgG subclass response to Helicobacter pylori in the first and third worlds. Scand J Gastroenterol 37:517-522. (Pubitemid 34522915)
53. Nyren O (1998). Is Helicobacter pylori really the cause of gastric cancer? Semin Cancer Biol 8:275-283.
54. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006; 118:3030-3044.
55. Peleteiro B, Bastos J, Barros H, Lunet N (2008). Systematic review of the prevalence of gastric intestinal metaplasia and its area-level association with smoking. Gac Sanit 22:236-247.
56. Peleteiro B, Lunet N, Carrilho C, Duraes C, Machado JC, La Vecchia C, et al. (2010a). Association between cytokine gene polymorphisms and gastric precancerous lesions: systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev 19:762-776.
57. Peleteiro B, Lunet N, Barros R, La Vecchia C, Barros H (2010b). Factors contributing to the underestimation of Helicobacter pylori-associated gastric cancer risk in a high-prevalence population. Cancer Causes Control 21:1257-1264.
58. Peleteiro B, Lopes C, Figueiredo C, Lunet N (2011a). Salt intake and gastric cancer risk according to Helicobacter pylori infection, smoking, tumour site and histological type. Br J Cancer 104:198-207.
59. Peleteiro B, Cavaleiro-Pinto M, Barros R, Barros H, Lunet N (2011b). Is cardia cancer aetiologically different from distal stomach cancer? Eur J Cancer Prev 20:96-101.
60. Pinto-de-Sousa J, David L, Reis CA, Gomes R, Silva L, Pimenta A (2002). Mucins, MUC1, MUC2, MUC5AC and MUC6 expression in the evaluation of differentiation and clinico-biological behaviour of gastric carcinoma. Virchows Arch 440:304-310. (Pubitemid 34230736)
61. Riboli E, Norat T (2003). Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. Am J Clin Nutr 78:559S-569S. (Pubitemid 40012550)
62. Rokkas T, Pistiolas D, Sechopoulos P, Robotis I, Margantinis G (2007). The long-term impact of Helicobacter pylori eradication on gastric histology: a systematic review and meta-analysis. Helicobacter 12 (Suppl 2):32-38. (Pubitemid 350076224)
63. Rothman KJ (1995). Causes (1976). Am J Epidemiol 141:90-95.
64. Tahara E (2004). Genetic pathways of two types of gastric cancer. IARC Sci Publ, 327-349.
65. The EUROGAST Study Group. (1993). An international association between Helicobacter pylori infection and gastric cancer. Lancet 341:1359-1362.
66. Thye T, Burchard GD, Nilius M, Muller-Myhsok B, Horstmann RD (2003). Genomewide linkage analysis identifies polymorphism in the human interferon-gamma receptor affecting Helicobacter pylori infection. Am J Hum Genet 72:448-453. (Pubitemid 36194252)
67. Tredaniel J, Boffetta P, Buiatti E, Saracci R, Hirsch A (1997). Tobacco smoking and gastric cancer: review and meta-analysis. Int J Cancer 72:565-573. (Pubitemid 27356154)
68. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, et al. (2001). Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345:784-789.
69. Vincenzi B, Patti G, Galluzzo S, Pantano F, Venditti O, Santini D, et al. (2008). Interleukin 1beta-511T gene (IL1beta) polymorphism is correlated with gastric cancer in the Caucasian population: results from a meta-analysis. Oncol Rep 20:1213-1220.
70. Wang C, Yuan Y, Hunt RH (2007). The association between Helicobacter pylori infection and early gastric cancer: a meta-analysis. Am J Gastroenterol 102:1789-1798. (Pubitemid 47206700)
71. Wang J, Xu L, Shi R, Huang X, Li SW, Huang Z, et al. (2011). Gastric atrophy and intestinal metaplasia before and after Helicobacter pylori eradication: a metaanalysis. Digestion 83:253-260.
72. Wang P, Xia HH, Zhang JY, Dai LP, Xu XQ, Wang KJ (2007). Association of interleukin-1 gene polymorphisms with gastric cancer: a meta-analysis. Int J Cancer 120:552-562. (Pubitemid 44969026)
73. Weck MN, Brenner H (2008). Association of Helicobacter pylori infection with chronic atrophic gastritis: meta-analyses according to type of disease definition. Int J Cancer 123:874-881. (Pubitemid 352032415)
74. Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, et al. (2004). Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA 291:187-194. (Pubitemid 38082812)
75. World Cancer Research Fund, American Institute for Cancer Research (2007). Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington DC: AICR.
76. Wu H, Rusiecki JA, Zhu K, Potter J, Devesa SS (2009). Stomach carcinoma incidence patterns in the United States by histologic type and anatomic site. Cancer Epidemiol Biomarkers Prev 18:1945-1952.
77. Xue FB, Xu YY,Wan Y, Pan BR, Ren J, Fan DM (2001). Association of H. pylori infection with gastric carcinoma: a meta analysis. World J Gastroenterol 7:801-804. (Pubitemid 34051497)