Duodenal lipid-induced symptom generation in gastroesophageal reflux disease: Role of apolipoprotein A-IV and cholecystokinin

Neurogastroenterology and Motility

Volumn 24, Issue 4, 2012, Pages

  van Boxel, O S ^a   ter Linde, J J M ^a   Oors, J ^a   Otto, B ^b   Feinle Bisset, C ^c   Smout, A J P M ^a   Siersema, P D ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Esophageal hypersensitivity; Fat; Small intestine

Indexed keywords

APOLIPOPROTEIN A4; CHOLECYSTOKININ; INTRALIPID;

ABDOMINAL DISCOMFORT; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DUODENUM; DUODENUM BIOPSY; FEMALE; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEARTBURN; HUMAN; HUMAN TISSUE; INTESTINE MUCOSA; INTESTINE PERFUSION; LIPID ABSORPTION; MALE; NAUSEA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; UPREGULATION;

ADULT; AGED; APOLIPOPROTEINS A; CENTRAL NERVOUS SYSTEM SENSITIZATION; CHOLECYSTOKININ; DUODENUM; EMULSIONS; FEMALE; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION PROFILING; HUMANS; LIPID METABOLISM; MALE; MIDDLE AGED; PHOSPHOLIPIDS; POLYMERASE CHAIN REACTION; SOYBEAN OIL;

EID: 84858288761     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2012.01880.x     Document Type: Article

References (44)

1. Bredenoord AJ, Weusten BL, Curvers WL et al. Determinants of perception of heartburn and regurgitation. Gut 2006; 55: 313-8.
2. Cicala M, Emerenziani S, Caviglia R et al. Intra-oesophageal distribution and perception of acid reflux in patients with non-erosive gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2003; 18: 605-13.
3. Weusten BL, Akkermans LM, vanBerge-Henegouwen GP et al. Symptom perception in gastroesophageal reflux disease is dependent on spatiotemporal reflux characteristics. Gastroenterology 1995; 108: 1739-44.
4. Sarkar S, Aziz Q, Woolf CJ et al. Contribution of central sensitisation to the development of non-cardiac chest pain. Lancet 2000; 356: 1154-9.
5. Mayer EA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994; 107: 271-93.
6. Hobson AR, Khan RW, Sarkar S et al. Development of esophageal hypersensitivity following experimental duodenal acidification. Am J Gastroenterol 2004; 99: 813-20.
7. Meyer JH, Lembo A, Elashoff JD et al. Duodenal fat intensifies the perception of heartburn. Gut 2001; 49: 624-8.
8. Barbera R, Feinle C, Read NW. Nutrient-specific modulation of gastric mechanosensitivity in patients with functional dyspepsia. Dig Dis Sci 1995; 40: 1636-41.
9. Feinle C, Meier O, Otto B et al. Role of duodenal lipid and cholecystokinin A receptors in the pathophysiology of functional dyspepsia. Gut 2001; 48: 347-55.
10. Whited KL, Lu D, Tso P et al. Apolipoprotein A-IV is involved in detection of lipid in the rat intestine. J Physiol 2005; 569(Pt 3): 949-58.
11. Kalogeris TJ, Rodriguez MD, Tso P. Control of synthesis and secretion of intestinal apolipoprotein A-IV by lipid. J Nutr 1997; 127: 537S-43S.
12. Rodriguez MD, Kalogeris TJ, Wang XL et al. Rapid synthesis and secretion of intestinal apolipoprotein A-IV after gastric fat loading in rats. Am J Physiol 1997; 272(4 Pt 2): R1170-7.
13. Glatzle J, Darcel N, Rechs AJ et al. Apolipoprotein A-IV stimulates duodenal vagal afferent activity to inhibit gastric motility via a CCK1 pathway. Am J Physiol Regul Integr Comp Physiol 2004; 287: R354-9.
14. de Vries DR, ter Linde JJ, van Boxel OS et al. In gastroesophageal reflux disease differential gene expression in the duodenum points towards enhanced chylomicron production and secretion. Digestive Diseases and Sciences. doi: 10.1007/s10620-012-2064-0 (in press).
15. Cartwright IJ, Higgins JA. Increased dietary triacylglycerol markedly enhances the ability of isolated rabbit enterocytes to secrete chylomicrons: an effect related to dietary fatty acid composition. J Lipid Res 1999; 40: 1858-66.
16. Mansbach CM, Nevin P. Intracellular movement of triacylglycerols in the intestine. J Lipid Res 1998; 39: 963-8.
17. Hayashi H, Nutting DF, Fujimoto K et al. Transport of lipid and apolipoproteins A-I and A-IV in intestinal lymph of the rat. J Lipid Res 1990; 31: 1613-25.
18. Kalogeris TJ, Fukagawa K, Tsuchiya T et al. Intestinal synthesis and lymphatic secretion of apolipoprotein A-IV after cessation of duodenal fat infusion: mediation by bile. Biochim Biophys Acta 1999; 1436: 451-66.
19. Weusten BL, Roelofs JM, Akkermans LM et al. The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data. Gastroenterology 1994; 107: 1741-5.
20. Feinle C, O'Donovan D, Doran S et al. Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans. Am J Physiol Gastrointest Liver Physiol 2003; 284: G798-807.
21. Cunningham KM, Baker RJ, Horowitz M et al. Use of technetium-99m(V)thiocyanate to measure gastric emptying of fat. J Nucl Med 1991; 32: 878-81.
22. Pilichiewicz AN, Little TJ, Brennan IM et al. Effects of load, and duration, of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men. Am J Physiol Regul Integr Comp Physiol 2006; 290: R668-77.
23. Green PH, Lefkowitch JH, Glickman RM et al. Apolipoprotein localization and quantitation in the human intestine. Gastroenterology 1982; 83: 1223-30.
24. Riepl RL, Lehnert P, Scharl A et al. Effect of intraduodenal bile and Na- taurodeoxycholate on exocrine pancreatic secretion and on plasma levels of secretin, pancreatic polypeptide, and gastrin in man. Scand J Gastroenterol 1990; 25: 45-53.
25. Rehfeld JF, Sun G, Christensen T et al. The predominant cholecystokinin in human plasma and intestine is cholecystokinin-33. J Clin Endocrinol Metab 2001; 86: 251-8.
26. Vandesompele J, De PK, Pattyn F et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: RESEARCH0034.
27. Apfelbaum TF, Davidson NO, Glickman RM. Apolipoprotein A-IV synthesis in rat intestine: regulation by dietary triglyceride. Am J Physiol 1987; 252(5 Pt 1): G662-6.
28. Bentouimou N, Leray V, Zerbib F et al. Expression of the gene of cholecystokinin demonstration from duodenal biopsies in man. Gastroenterol Clin Biol 1995; 19: 659-63.
29. Trudgill NJ, Hussain FN, Moustafa M et al. The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with reflux disease. Aliment Pharmacol Ther 2001; 15: 1357-64.
30. Lal S, Kirkup AJ, Brunsden AM et al. Vagal afferent responses to fatty acids of different chain length in the rat. Am J Physiol Gastrointest Liver Physiol 2001; 281: G907-15.
31. Feinle C, D'Amato M, Read NW. Cholecystokinin-A receptors modulate gastric sensory and motor responses to gastric distension and duodenal lipid. Gastroenterology 1996; 110: 1379-85.
32. Feinle C, Grundy D, Fried M. Modulation of gastric distension-induced sensations by small intestinal receptors. Am J Physiol Gastrointest Liver Physiol 2001; 280: G51-7.
33. Urban MO, Gebhart GF. Supraspinal contributions to hyperalgesia. Proc Natl Acad Sci USA 1999; 96: 7687-92.
34. Khasar SG, Miao JP, Janig W et al. Modulation of bradykinin-induced mechanical hyperalgesia in the rat by activity in abdominal vagal afferents. Eur J Neurosci 1998; 10: 435-44.
35. Tien D, Ohara PT, Larson AA et al. Vagal afferents are necessary for the establishment but not the maintenance of kainic acid-induced hyperalgesia in mice. Pain 2003; 102: 39-49.
36. Watkins LR, Wiertelak EP, Goehler LE et al. Neurocircuitry of illness-induced hyperalgesia. Brain Res 1994; 639: 283-99.
37. Platica O, Chen S, Ivan E, Lopingco MC, Holland JF, Platica M. PAR, a novel androgen regulated gene, ubiquitously expressed in normal and malignant cells. Int J Oncol 2000; 16: 1055-61.
38. Swinnen JV, Ulrix W, Heyns W et al. Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins. Proc Natl Acad Sci USA 1997; 94: 12975-80.
39. Carrier JC, Deblois G, Champigny C et al. Estrogen-related receptor alpha (ERRalpha) is a transcriptional regulator of apolipoprotein A-IV and controls lipid handling in the intestine. J Biol Chem 2004; 279: 52052-8.
40. Wang Q, Sharma D, Ren Y et al. A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression. J Biol Chem 2002; 277: 42852-8.
41. Ungewickell A, Hugge C, Kisseleva M et al. The identification and characterization of two phosphatidylinositol-4, 5-bisphosphate 4-phosphatases. Proc Natl Acad Sci USA 2005; 102: 18854-9.
42. Quigley EM. Non-erosive reflux disease: part of the spectrum of gastro-oesophageal reflux disease, a component of functional dyspepsia, or both? Eur J Gastroenterol Hepatol 2001; 13(Suppl. 1): S13-8.
43. Knowles CH, Aziz Q. Visceral hypersensitivity in non-erosive reflux disease. Gut 2008; 57: 674-83.
44. French SJ, Conlon CA, Mutuma ST et al. The effects of intestinal infusion of long-chain fatty acids on food intake in humans. Gastroenterology 2000; 119: 943-8.