Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development

Journal of Investigative Dermatology

Volumn 132, Issue 4, 2012, Pages 1094-1102

  Lefebvre, Sylvie ^a   Fliniaux, Ingrid ^a,c   Schneider, Pascal ^b   Mikkola, Marja L ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; ECTODYSPLASIN A; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; WNT PROTEIN;

ANIMAL TISSUE; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; HAIR FOLLICLE; HAIR GROWTH; HYPOHIDROTIC ECTODERMAL DYSPLASIA; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SKIN APPENDAGE; UPREGULATION;

EID: 84858281892     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.453     Document Type: Article

References (55)

1. Banisadr G, Bhattacharyya BJ, Belmadani A et al. (2011) The chemokine BRAK/CXCL14 regulates synaptic transmission in the adult mouse dentate gyrus stem cell niche. J Neurochem 119:1173-82
2. Belmadani A, Jung H, Ren D et al. (2009) The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles. Differentiation 77:395-411
3. Bunting K, Rao S, Hardy K et al. (2007) Genome-wide analysis of gene expression in T cells to identify targets of the NF-kB transcription factor c-Rel. J Immunol 178:7097-109
4. Cui CY, Durmowicz M, Ottolenghi C et al. (2003) Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential formation of two types of mouse hair follicles. Hum Mol Genet 12:2931-40
5. Cui CY, Hashimoto T, Grivennikov SI et al. (2006) Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci USA 103:9142-7
6. Duverger O, Morasso MI (2009) Epidermal patterning and induction of different hair types during mouse embryonic development. Birth Defects Res C Embryo Today 87:263-72
7. Fliniaux I, Mikkola ML, Lefebvre S et al. (2008) Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes. Dev Biol 320:60-71
8. Fuchs E (2007) Scratching the surface of skin development. Nature 445:834-42
9. Gaide O, Schneider P (2003) Permanent correction of an inherited ectodermal dysplasia with recombinant EDA. Nat Med 9:614-8
10. Garcia-Andres C, Torres M (2010) Comparative expression pattern analysis of the highly conserved chemokines SDF1 and CXCL14 during amniote embryonic development. Dev Dyn 239:2769-77
11. Gum R, Lengyel E, Juarez J et al. (1996) Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-Activated protein kinase kinase 1- independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J Biol Chem 271:10672-80
12. Hammerschmidt B, Schlake T (2007) Localization of Shh expression by Wnt and Eda affects axial polarity and shape of hairs. Dev Biol 305:246-61
13. Headon DJ, Emmal SA, Ferguson BM et al. (2001) Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature 414:913-5
14. Headon DJ, Overbeek PA (1999) Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet 22:370-4
15. Hoser M, Potzner MR, Koch JM et al. (2008) Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol 28:4675-87
16. Jiang TX, Widelitz RB, Shen WM et al. (2004) Integument pattern formation involves genetic and epigenetic controls: Feather arrays simulated by digital hormone models. Int J Dev Biol 48:117-35
17. Kere J, Srivastava AK, Montonen O et al. (1996) X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet 13:409-15
18. Kiso M, Tanaka S, Saba R et al. (2009) The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proc Natl Acad Sci USA 106:9292-7
19. Koppinen P, Pispa J, Laurikkala J et al. (2001) Signaling and subcellular localization of the TNF receptor Edar. Exp Cell Res 269:180-92
20. Kroeze KL, Boink MA, Sampat-Sardjoepersad SC et al. (2011) Autocrine regulation of re-epithelialization after wounding by chemokine receptors CCR1, CCR10, CXCR1, CXCR2, and CXCR3. J Invest Dermatol 132:216-25
21. Lacotte S, Brun S, Muller S et al. (2009) CXCR3, inflammation, and autoimmune diseases. Ann N Y Acad Sci 1173:310-7
22. Laurikkala J, Pispa J, Jung HS et al. (2002) Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development 129:2541-53
23. Lippens S, Lefebvre S, Gilbert B et al. (2011) Keratinocyte-specific ablation of the NF-kB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis. Cell Death Differ 18:1845-53
24. Martin P (1990) Tissue patterning in the developing mouse limb. Int J Dev Biol 34:323-35
25. Mikkola ML (2008) TNF superfamily in skin appendage development. Cytokine Growth Factor Rev 19:219-30
26. Mikkola ML (2009) Molecular aspects of hypohidrotic ectodermal dysplasia. Am J Med Genet A 149A:2031-5
27. Miller RJ, Banisadr G, Bhattacharyya BJ (2008) CXCR4 signaling in the regulation of stem cell migration and development. J Neuroimmunol 198:31-8
28. Monreal AW, Ferguson BM, Headon DJ et al. (1999) Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet 22:366-9
29. Mou C, Jackson B, Schneider P et al. (2006) Generation of the primary hair follicle pattern. Proc Natl Acad Sci USA 103:9075-80
30. Müller-Rover S, Bulfone-Paus S, Handjiski B et al. 2000 Intercellular adhesion molecule-1 and hair follicle regression. J Histochem Cytochem 48 557-68
31. Mustonen T, Ilmonen M, Pummila M et al. (2004) Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development 131:4907-19
32. Mustonen T, Pispa J, Mikkola ML et al. (2003) Stimulation of ectodermal organ development by Ectodysplasin-A1. Dev Biol 259:123-35
33. Närhi K, Järvinen E, Birchmeier W et al. (2008) Sustained epithelial b-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. Development 135:1019-28
34. Nishioka E, Tanaka T, Yoshida H et al. (2002) Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair. J Invest Dermatol 119:632-8
35. Nowak JA, Polak L, Pasolli HA et al. (2008) Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell 3:33-43
36. Ohmori Y, Hamilton TA (1995) The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-g and TNF-A. J Immunol 154:5235-44
37. Pispa J, Pummila M, Barker PA et al. (2008) Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet 17:3380-91
38. Pummila M, Fliniaux I, Jaatinen R et al. (2007) Ectodysplasin has a dual role in ectodermal organogenesis: Inhibition of Bmp activity and induction of Shh expression. Development 134:117-25
39. Rossi D, Zlotnik A (2000) The biology of chemokines and their receptors. Annu Rev Immunol 18:217-42
40. Sandelin A, Wasserman WW, Lenhard B (2004) ConSite: Web-based prediction of regulatory elements using cross-species comparison. Nucleic Acids Res 32:W249-52
41. Satish L, Yager D, Wells A (2003) Glu-Leu-Arg-negative CXC chemokine interferon gamma inducible protein-9 as a mediator of epidermaldermal communication during wound repair. J Invest Dermatol 120:1110-7
42. Schlake T (2007) Determination of hair structure and shape. Semin Cell Dev Biol 18:267-73
43. Schmidt-Ullrich R, Tobin DJ, Lenhard D et al. (2006) NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 133:1045-57
44. Schneider MR, Schmidt-Ullrich R, Paus R (2009) The hair follicle as a dynamic miniorgan. Curr Biol 19:R132-42
45. Scott CA, Tattersall D, O'Toole EA et al. (2011) Connexins in epidermal homeostasis and skin disease. Biochim Biophys Acta; advance online publication 10 September 2011
46. Sharov AA, Schroeder M, Sharova TY et al. (2011) Matrix metalloproteinase-9 is involved in the regulation of hair canal formation. J Invest Dermatol 131:257-60
47. Shin SY, Nam JS, Lim Y et al. (2010) TNFalpha-exposed bone marrow-derived mesenchymal stem cells promote locomotion of MDA-MB-231 breast cancer cells through transcriptional activation of CXCR3 ligand chemokines. J Biol Chem 285:30731-40
48. Sick S, Reinker S, Timmer J et al. (2006) WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanism. Science 314:1447-50
49. Takeuchi M, Baichwal VR (1995) Induction of the gene encoding mucosal vascular addressin cell adhesion molecule 1 by tumor necrosis factor alpha is mediated by NF-kB proteins. Proc Natl Acad Sci USA 92:3561-5
50. Tensen CP, Flier J, Rampersad SS et al. (1999) Genomic organization, sequence and transcriptional regulation of the human CXCL 111 gene. Biochim Biophys Acta 1446:167-72
51. Thiefes A, Wolter S, Mushinski JF et al. (2005) Simultaneous blockade of NFkB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor target genes. J Biol Chem 280: 27728-41
52. Vidal VP, Chaboissier MC, Lutzkendorf S et al. (2005) Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol 15:1340-51
53. Yates CC, Whaley D, Hooda S et al. (2009) Delayed reepithelialization and basement membrane regeneration after wounding in mice lacking CXCR3. Wound Repair Regen 17:34-41
54. Zhang Y, Tomann P, Andl T et al. (2009) Reciprocal requirements for EDA/ EDAR/NF-kB and Wnt/b-catenin signaling pathways in hair follicle induction. Dev Cell 17:49-61
55. Zlotnik A, Yoshie O (2000) Chemokines: A new classification system and their role in immunity. Immunity 12:121-7