Cobalt and chromium ions reduce human osteoblast-like cell activity in vitro, reduce the OPG to RANKL ratio, and induce oxidative stress

Journal of Orthopaedic Research

Volumn 30, Issue 5, 2012, Pages 740-747

  Zijlstra, Wierd P ^a,b   Bulstra, Sjoerd K ^b   Van Raay, Jos J A M ^c   Van Leeuwen, Babs M ^b   Kuijer, Roel ^b  

^a MEDICAL CENTER LEEUWARDEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c MARTINI HOSPITAL   (Netherlands)

Author keywords

metal on metal; OPG; osteoblasts; oxidative stress; RANKL

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CATALASE; CHROMIUM; COBALT; CRYSTAL VIOLET; GLUTATHIONE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; RNA; SUPEROXIDE DISMUTASE;

ARTICLE; CELL ACTIVITY; CELL COUNT; CONTROLLED STUDY; ENZYME BLOOD LEVEL; HIP ARTHROPLASTY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TIME; OSTEOBLAST; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

CELL LINE, TUMOR; CHROMIUM; COBALT; HUMANS; OSTEOBLASTS; OSTEOPROTEGERIN; OXIDATIVE STRESS; RANK LIGAND;

EID: 84858279018     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21581     Document Type: Article

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