The correlation of RANK, RANKL and TNFα expression with bone loss volume and polyethylene wear debris around hip implants

Biomaterials

Volumn 27, Issue 30, 2006, Pages 5212-5219

  Holding, Christopher A ^a   Findlay, David M ^a,b   Stamenkov, Roumen ^a   Neale, Susan D ^a   Lucas, Helen ^a   Dharmapatni, A S S K ^a   Callary, Stuart A ^a   Shrestha, Kush R ^a,b   Atkins, Gerald J ^a   Howie, Donald W ^a,b   Haynes, David R ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b HANSON INSTITUTE   (Australia)

Author keywords

Image analysis; Osteoclast; Osteolysis; Polyethylene; Wear debris

Indexed keywords

CELLS; PROSTHETICS; TISSUE; TUMORS; WEAR OF MATERIALS;

OSTEOCLAST; OSTEOLYSIS; POLYETHYLENE; WEAR DEBRIS;

POLYETHYLENES;

FORMALDEHYDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METAL; OSTEOCLAST DIFFERENTIATION FACTOR; POLYETHYLENE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BONE TURNOVER; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMPLANT; IN VITRO STUDY; INTERMETHOD COMPARISON; MALE; MULTINUCLEAR CELL; OPTICAL RESOLUTION; OSSIFICATION; OSTEOARTHRITIS; OSTEOCLAST; OSTEOLYSIS; PARAMETERS OF MEASUREMENT AND ANALYSIS; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REOPERATION; STATISTICAL ANALYSIS; SYNOVIUM; TISSUE SECTION; TOTAL HIP PROSTHESIS;

ARTHROPLASTY, REPLACEMENT, HIP; BONE RESORPTION; CARRIER PROTEINS; GLYCOPROTEINS; HIP; HIP PROSTHESIS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; OSTEOCLASTS; OSTEOLYSIS; OSTEOPROTEGERIN; POLYETHYLENES; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; TOMOGRAPHY, X-RAY COMPUTED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33746061250     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.05.054     Document Type: Article

References (36)

1. Graves S.E., Davidson D., Ingerson L., Ryan P., Griffith E.C., McDermott B.F., et al. The Australian Orthopaedic Association National Joint Replacement Registry. Med J Aust 180 (2004) S31-S34
2. Harris W.H. The problem is osteolysis. Clin Orthop Relat Res (1995) 46-53
3. Howie D.W., Cornish B.L., and Vernon-Roberts B. Resurfacing hip arthroplasty. Classification of loosening and the role of prosthesis wear particles. Clin Orthop Relat Res (1990) 144-159
4. Santavirta S., Hoikka V., Eskola A., Konttinen Y.T., Paavilainen T., and Tallroth K. Aggressive granulomatous lesions in cementless total hip arthroplasty. J Bone Joint Surg Br 72 (1990) 980-984
5. al Saffar N., and Revell P.A. Interleukin-1 production by activated macrophages surrounding loosened orthopaedic implants: a potential role in osteolysis. Br J Rheumatol 33 (1994) 309-316
6. Matthews J.B., Green T.R., Stone M.H., Wroblewski B.M., Fisher J., and Ingham E. Comparison of the response of three human monocytic cell lines to challenge with polyethylene particles of known size and dose. J Mater Sci Mater Med 12 (2001) 249-258
7. Quinn J.M., Neale S., Fujikawa Y., McGee J.O., and Athanasou N.A. Human osteoclast formation from blood monocytes, peritoneal macrophages, and bone marrow cells. Calcif Tissue Int 62 (1998) 527-531
8. Haynes D.R., Crotti T.N., Potter A.E., Loric M., Atkins G.J., Howie D.W., et al. The osteoclastogenic molecules RANKL and RANK are associated with periprosthetic osteolysis. J Bone Joint Surg Br 83 (2001) B902-B911
9. Looney R.J., Boyd A., Totterman S., Seo G.S., Tamez-Pena J., Campbell D., et al. Volumetric computerized tomography as a measurement of periprosthetic acetabular osteolysis and its correlation with wear. Arthritis Res 4 (2002) 59-63
10. Orishimo K.F., Claus A.M., Sychterz C.J., and Engh C.A. Relationship between polyethylene wear and osteolysis in hips with a second-generation porous-coated cementless cup after seven years of follow-up. J Bone Joint Surg Am 85-A (2003) 1095-1099
11. Howie D.W., Vernon-Roberts B., Oakeshott R., and Manthey B. A rat model of resorption of bone at the cement-bone interface in the presence of polyethylene wear particles. J Bone Joint Surg 70-A (1988) 257-263
12. Kim K.J., Kobayashi Y., and Itoh T. Osteolysis model with continuous infusion of polyethylene particles. Clin Orthop Relat Res (1998) 46-52
13. Brooks R.A., Sharpe J.R., Wimhurst J.A., Myer B.J., Dawes E.N., and Rushton N. The effects of the concentration of high-density polyethylene particles on the bone-implant interface. J Bone Joint Surg Br 82 (2000) 595-600
14. Ren W., Yang S.Y., and Wooley P.H. A novel murine model of orthopaedic wear-debris associated osteolysis. Scand J Rheumatol 33 (2004) 349-357
15. Horowitz S.M., and Gonzales J.B. Effects of polyethylene on macrophages. J Orthop Res 15 (1997) 50-56
16. Rader C.P., Sterner T., Jakob F., Schutze N., and Eulert J. Cytokine response of human macrophage-like cells after contact with polyethylene and pure titanium particles. J Arthroplasty 14 (1999) 840-848
17. Baumann B., Rader C.P., Seufert J., Noth U., Rolf O., Eulert J., et al. Effects of polyethylene and TiAlV wear particles on expression of RANK, RANKL and OPG mRNA. Acta Orthop Scand 75 (2004) 295-302
18. Garrigues G.E., Cho D.R., Rubash H.E., Goldring S.R., Herndon J.H., and Shanbhag A.S. Gene expression clustering using self-organizing maps: analysis of the macrophage response to particulate biomaterials. Biomaterials 26 (2005) 2933-2945
19. Hofbauer L.C., Khosla S., Dunstan C.R., Lacey D.L., Boyle W.J., and Riggs B.L. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 15 (2000) 2-12
20. Haynes D.R. Bone lysis and inflammation. Inflamm Res 53 (2004) 596-600
21. Crotti T.N., Smith M.D., Findlay D.M., Zreiqat H., Ahern M.J., Weedon H., et al. Factors regulating osteoclast formation in human tissues adjacent to peri-implant bone loss: expression of receptor activator NFkappaB, RANK ligand and osteoprotegerin. Biomaterials 25 (2004) 565-573
22. Jiranek W.A., Machado M., Jasty M., Jevsevar D., Wolfe H.J., Goldring S.R., et al. Production of cytokines around loosened cemented acetabular components. J Bone Joint Surg 75-A (1993) 863-879
23. Fuller K., Murphy P.M., Kirstein B., Fox S.W., and Chambers T.J. TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL. Endocrinology 143 (2002) 1108-1118
24. Stamenkov R., Howie D., Taylor J., Findlay D., McGee M., Kourlis G., et al. Measurement of bone defects adjacent to acetabular components of hip replacement. Clin Orthop Relat Res (2003) 117-124
25. Link T.M., Berning W., Scherf S., Joosten U., Joist A., Engelke K., et al. CT of metal implants: reduction of artifacts using an extended CT scale technique. J Comput Assist Tomogr 24 (2000) 165-172
26. Hansen T., Otto M., Gaumann A., Petrow P.K., Delank K.S., Kirkpatrick C.J., et al. Cathepsin K in aseptic hip prosthesis loosening: expression in osteoclasts without polyethylene wear particles. J Rheumatol 28 (2001) 1615-1619
27. Haynes D.R., Atkins G.J., Loric M., Crotti T.N., Geary S.M., and Findlay D.M. Bidirectional signaling between stromal and hemopoietic cells regulates interleukin-1 expression during human osteoclast formation. Bone 25 (1999) 269-278
28. Haynes D.R., Crotti T.N., and Zreiqat H. Regulation of osteoclast activity in peri-implant tissues. Biomaterials 25 (2004) 4877-4885
29. Anderson D.M., Marakovsky E., and Billinglsey W.L. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic function. Nature 390 (1997) 175-179
30. Kobayashi K., Takahashi N., Jimi E., Udagawa N., Takami M., Kotake S., et al. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 191 (2000) 275-285
31. Sabokbar A., Kudo O., and Athanasou N.A. Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis. J Orthop Res 21 (2003) 73-80
32. Lam J., Takeshita S., Barker J.E., Kanagawa O., Ross F.P., and Teitelbaum S.L. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 106 (2000) 1481-1488
33. Frick K.K., LaPlante K., and Bushinsky D.A. RANK ligand and TNF-alpha mediate acid-induced bone calcium efflux in vitro. Am J Physiol Renal Physiol 289 (2005) F1005-F1011
34. Lee Z.H., Lee S.E., Kim C.W., Lee S.H., Kim S.W., Kwack K., et al. IL-1alpha stimulation of osteoclast survival through the PI 3-kinase/Akt and ERK pathways. J Biochem (Tokyo) 131 (2002) 161-166
35. Zhang Q., Badell I.R., Schwarz E.M., Boulukos K.E., Yao Z., Boyce B.F., et al. Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2. Arthritis Rheum 52 (2005) 2708-2718
36. Schwarz E.M., Campbell D., Totterman S., Boyd A., O'Keefe R.J., and Looney R.J. Use of volumetric computerized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri-prosthetic osteolysis: a 1-year clinical pilot of etanercept vs. placebo. J Orthop Res 21 (2003) 1049-1055