The effects of a gentle yoga program on sleep, mood, and blood pressure in older women with restless legs syndrome (RLS): A preliminary randomized controlled trial

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Innes, Kim E ^a,b   Selfe, Terry Kit ^a,b  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANXIETY; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; EDUCATION PROGRAM; EFFECT SIZE; FEMALE; FILM; HEART RATE; HUMAN; INSOMNIA; MOOD; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OUTCOME ASSESSMENT; PERCEIVED STRESS SCALE; PITTSBURGH SLEEP QUALITY INDEX; PREVALENCE; PRIORITY JOURNAL; PROFILE OF MOOD STATES STATE TRAIT ANXIETY INVENTORY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESTLESS LEGS SYNDROME; SLEEP; SLEEP QUALITY; STRESS; SYMPATHETIC FUNCTION; YOGA;

EID: 84858275731     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/294058     Document Type: Article

References (119)

1. Innes K. E., Selfe T. K., Agarwal P., Prevalence of restless legs syndrome in North American and Western European populations: a systematic review Sleep Medicine 2011 12 7 623 634
2. Allen R. P., Picchietti D., Hening W. A., Trenkwalder C., Walters A. S., Montplaisi J., Bara-Jimenez W., Becker P., Bell G., Berger K., Bliwise D. L., Brooks D., Consens F., Earley C. J., Ehrenberg B. L., Foley D., Murray C. F., Garcia-Borreguero D., Hallett M., Hornyak M., Hunt C. E., Kushida C., Kurth T., Launer L., Monjan A., Nichols P., Rye D. B., Sharon D., Streiner D. L., Winkelman J. W., Winkelmann J., Zak R., Adler C., Benes H., Chokroverty S., Ekbom K., Frauscher B., Hgl B., Kryger M., Montagna P., Oertel W., Plazzi G., Poceta J. S., Silber M., Stiasny K., Tolosa E., Tufik S., de Mello M. T., Zucconi M., Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health Sleep Medicine 2003 4 2 101 119 (Pubitemid 36527231)
3. Abetz L., Allen R., Follet A., Washburn T., Early C., Kirsch J., Knight H., Evaluating the quality of life of patients with restless legs syndrome Clinical Therapeutics 2004 26 6 925 935 (Pubitemid 38943041)
4. Reese J. P., Stiasny-Kolster K., Oertel W. H., Dodel R. C., Health-related quality of life and economic burden in patients with restless legs syndrome Expert Review of Pharmacoeconomics and Outcomes Research 2007 7 5 503 521 (Pubitemid 350120044)
5. Reinhold T., Mller-Riemenschneider F., Willich S. N., Brggenjrgen B., Economic and human costs of restless legs syndrome PharmacoEconomics 2009 27 4 267 279
6. Happe S., Reese J. P., Stiasny-Kolster K., Peglau I., Mayer G., Klotsche J., Giani G., Geraedts M., Trenkwalder C., Dodel R., Assessing health-related quality of life in patients with restless legs syndrome Sleep Medicine 2009 10 3 295 305
7. Earley C. J., Silber M. H., Restless legs syndrome: understanding its consequences and the need for better treatment Sleep Medicine 2010 11 9 807 815
8. Winkelman J. W., Considering the causes of RLS European Journal of Neurology 2006 13 2 8 14
9. Walters A. S., Rye D. B., Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke Sleep 2009 32 5 589 597
10. Smith J. E., Tolson J. M., Recognition, diagnosis, and treatment of restless legs syndrome Journal of the American Academy of Nurse Practitioners 2008 20 8 396 401
11. Matthews W. B., Letter: iron deficiency and restless legs British Medical Journal 1976 1 6014 898
12. Sandyk R., The restless legs syndrome (Ekbom's syndrome) South African Medical Journal 1983 63 18 701 702 (Pubitemid 13097139)
13. O'Keeffe S. T., Restless legs syndrome: a review Archives of Internal Medicine 1996 156 3 243 248 (Pubitemid 26058474)
14. Allen R., Dopamine and iron in the pathophysiology of restless legs syndrome (RLS) Sleep Medicine 2004 5 4 385 391
15. Trotti L. M., Bhadriraju S., Rye D. B., An update on the pathophysiology and genetics of restless legs syndrome Current Neurology and Neuroscience Reports 2008 8 4 281 287
16. Ekbom K., Ulfberg J., Restless legs syndrome Journal of Internal Medicine 2009 266 5 419 431
17. Trenkwalder C., Hgl B., Winkelmann J., Recent advances in the diagnosis, genetics and treatment of restless legs syndrome Journal of Neurology 2009 256 4 539 553
18. Trenkwalder C., Paulus W., Restless legs syndrome: pathophysiology, clinical presentation and management Nature Reviews Neurology 2010 6 6 337 346
19. Earley C. J., Allen R. P., Connor J. R., Ferrucci L., Troncoso J., The dopaminergic neurons of the A11 system in RLS autopsy brains appear normal Sleep Medicine 2009 10 10 1155 1157
20. McDonagh B., King T., Guptan R. C., Restless legs syndrome in patients with chronic venous disorders: an untold story Phlebology 2007 22 4 156 163
21. Innes K. E., Selfe T. K., Agarwal P., Restless legs syndrome and conditions associated with metabolic dysregulation, sympathoadrenal dysfunction, and cardiovascular disease risk: a systematic review Sleep Medicine Reviews 2011 38 5 1 31
22. Ferri R., Zucconi M., Rundo F., Spruyt K., Manconi M., Ferini-Strambi L., Heart rate and spectral EEG changes accompanying periodic and non-periodic leg movements during sleep Clinical Neurophysiology 2007 118 2 438 448 (Pubitemid 46038815)
23. Siddiqui F., Strus J., Ming X., Lee I. A., Chokroverty S., Walters A. S., Rise of blood pressure with periodic limb movements in sleep and wakefulness Clinical Neurophysiology 2007 118 9 1923 1930 (Pubitemid 47187754)
24. Pennestri M. H., Montplaisir J., Colombo R., Lavigne G., Lanfranchi P. A., Nocturnal blood pressure changes in patients with restless legs syndrome Neurology 2007 68 15 1213 1218 (Pubitemid 46608469)
25. Schilling C., Schredl M., Strobl P., Deuschle M., Restless legs syndrome: evidence for nocturnal hypothalamic-pituitary- adrenal system activation Movement Disorders 2010 25 8 1047 1052
26. Cikrikcioglu M. A., Hursitoglu M., Erkal H., Kinas B. E., Sztajzel J., Cakirca M., Arslan A. G., Erek A., Halac G., Tukek T., Oxidative stress and autonomic nervous system functions in restless legs syndrome European Journal of Clinical Investigation 2011 41 7 734 742
27. Ferrin-Strambi L., Poccia F., Oldani A., Heart rate variability during wakefulness and sleep in restless legs Syndrome Journal of Sleep Research 2000 9, article 63
28. Oertel W. H., Trenkwalder C., Zucconi M., Benes H., Borreguero D. G., Bassetti C., Partinen M., Ferini-Strambi L., Stiasny-Kolster K., State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome Movement Disorders 2007 22 supplement 18 S466 S475
29. Spiegelhalder K., Hornyak M., Restless legs syndrome in older adults Clinics in Geriatric Medicine 2008 24 1 167 180 (Pubitemid 351491169)
30. Trenkwalder C., Hening W. A., Montagna P., Oertel W. H., Allen R. P., Walters A. S., Costa J., Stiasny-Kolster K., Sampaio C., Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice Movement Disorders 2008 23 16 2267 2302
31. Garca-Borreguero D., Williams A. M., Dopaminergic augmentation of restless legs syndrome Sleep Medicine Reviews 2010 14 5 339 346
32. Milligan S. A., Chesson A. L., Restless legs syndrome in the older adult: diagnosis and management Drugs and Aging 2002 19 10 741 751 (Pubitemid 35305833)
33. Wolkove N., Elkholy O., Baltzan M., Palayew M., Sleep and aging: 2. Management of sleep disorders in older people CMAJ 2007 176 10 1449 1454 (Pubitemid 46762024)
34. Cochen V., Arbus C., Soto M. E., Villars H., Tiberge M., Montemayor T., Hein C., Veccherini M. F., Onen S. H., Ghorayeb I., Verny M., Fitten L. J., Savage J., Dauvilliers Y., Vellas B., Sleep disorders and their impacts on healthy, dependent, and frail older adults Journal of Nutrition, Health and Aging 2009 13 4 322 329
35. Winkelman J. W., Johnston L., Augmentation and tolerance with long-term pramipexole treatment of restless legs syndrome (RLS) Sleep Medicine 2004 5 1 9 14 (Pubitemid 38145706)
36. Garcia-Borreguero D., Allen R., Kohnen R., Benes H., Winkelman J., Hgl B., Ferini-Strambi L., Zucconi M., Trenkwalder C., Loss of response during long-term treatment of restless legs syndrome: guidelines approved by the International Restless Legs Syndrome Study Group for use in clinical trials Sleep Medicine 2010 11 9 956 957
37. Sakkas G. K., Hadjigeorgiou G. M., Karatzaferi C., Maridaki M. D., Giannaki C. D., Mertens P. R., Rountas C., Vlychou M., Liakopoulos V., Stefanidis I., Intradialytic aerobic exercise training ameliorates symptoms of restless legs syndrome and improves functional capacity in patients on hemodialysis: a pilot study ASAIO Journal 2008 54 2 185 190 (Pubitemid 351450764)
38. Aukerman M. M., Aukerman D., Bayard M., Tudiver F., Thorp L., Bailey B., Exercise and restless legs syndrome: a randomized controlled trial Journal of the American Board of Family Medicine 2006 19 5 487 493 (Pubitemid 44577207)
39. Hornyak M., Grossmann C., Kohnen R., Schlatterer M., Richter H., Voderholzer U., Riemann D., Berger M., Cognitive behavioural group therapy to improve patients' strategies for coping with restless legs syndrome: a proof-of-concept trial Journal of Neurology, Neurosurgery and Psychiatry 2008 79 7 823 825 (Pubitemid 351914733)
40. Barnes P. M., Bloom B., Nahin R. L., Complementary and alternative medicine use among adults and children: United States, 2007 National Health Statistics Reports 2009 12 1 23
41. Yang K., A review of yoga programs for four leading risk factors of chronic diseases Evidence-Based Complementary and Alternative Medicine 2007 4 4 487 491
42. Innes K. E., Vincent H. K., The influence of yoga-based programs on risk profiles in adults with type 2 diabetes mellitus: a systematic review Evidence-Based Complementary and Alternative Medicine 2007 4 4 469 486
43. Gordon L. A., Morrison E. Y., McGrowder D. A., Young R., Fraser Y. T. P., Zamora E., Alexander-Lindo R. L., Irving R. R., Effect of exercise therapy on lipid profile and oxidative stress indicators in patients with type 2 diabetes BMC Complementary and Alternative Medicine 2008 8, article 21
44. Ross A., Thomas S., The health benefits of yoga and exercise: a review of comparison studies Journal of Alternative and Complementary Medicine 2010 16 1 3 12
45. Innes K. E., Selfe T. K., Taylor A. G., Menopause, the metabolic syndrome, and mind-body therapies Menopause 2008 15 5 1005 1013
46. Khalsa S. B. S., Shorter S. M., Cope S., Wyshak G., Sklar E., Yoga ameliorates performance anxiety and mood disturbance in young professional musicians Applied Psychophysiology Biofeedback 2009 34 4 279 289
47. Butler L. D., Waelde L. C., Hastings T. A., Chen X. H., Symons B., Marshall J., Kaufman A., Nagy T. F., Blasey C. M., Seibert E. O., Spiegel D., Meditation with yoga, group therapy with hypnosis, and psychoeducation for long-term depressed mood: a randomized pilot trial Journal of Clinical Psychology 2008 64 7 806 820 (Pubitemid 351969756)
48. Chen K. M., Chen M. H., Lin M. H., Fan J. T., Lin H. S., Li C. H., Effects of yoga on sleep quality and depression in elders in assisted living facilities The Journal of Nursing Research 2010 18 1 53 61
49. Innes K. E., Selfe T. K., Vishnu A., Mind-body therapies for menopausal symptoms: a systematic review Maturitas 2010 66 2 135 149
50. Chen K. M., Chen M. H., Chao H. C., Hung H. M., Lin H. S., Li C. H., Sleep quality, depression state, and health status of older adults after silver yoga exercises: cluster randomized trial International Journal of Nursing Studies 2009 46 2 154 163
51. Yurtkuran M., Alp A., Yurtkuran M., Dilek K., A modified yoga-based exercise program in hemodialysis patients: a randomized controlled study Complementary Therapies in Medicine 2007 15 3 164 171 (Pubitemid 47260319)
52. Bhatnagar O. P., Anantharaman V., The effect of Yoga training on neuromuscular excitability and muscular relaxation Neurology India 1977 25 4 230 232 (Pubitemid 8272865)
53. Tergau F., Wischer S., Paulus W., Motor system excitability in patients with restless legs syndrome Neurology 1999 52 5 1060 1063 (Pubitemid 29161620)
54. Scalise A., Pittaro-Cadore I., Janes F., Marinig R., Gigli G. L., Changes of cortical excitability after dopaminergic treatment in restless legs syndrome Sleep Medicine 2010 11 1 75 81
55. Chaudhuri K. R., The restless legs syndrome: time to recognize a very common movement disorder Practical Neurology 2003 3 4 204 213 (Pubitemid 36974702)
56. MacMahon D., Muzerengi S., Chaudhuri K. R., Treatment and identification of restless legs syndrome Prescriber 2008 5 56 59
57. Innes K. E., Selfe T. K., Alexander G. K., Taylor A. G., A new educational film control for use in studies of active mind-body therapies: acceptability and feasibility Journal of Alternative and Complementary Medicine 2011 17 5 453 458
58. Buysse D. J., Reynolds C. F., Monk T. H., Berman S. R., Kupfer D. J., The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research Psychiatry Research 1989 28 2 193 213 (Pubitemid 19144991)
59. Cohen S., Kamarck T., Mermelstein R., A global measure of perceived stress Journal of Health and Social Behavior 1983 24 4 385 396
60. Berger B. G., Motl R. W., Exercise and mood: a selective review and synthesis of research employing the Profile of Mood States Journal of Applied Sport Psychology 2000 12 1 69 92
61. Ramanaiah N. V., Franzen M., Schill T., A psychometric study of the State-Trait Anxiety Inventory Journal of Personality Assessment 1983 47 5 531 535
62. Backhaus J., Junghanns K., Broocks A., Riemann D., Hohagen F., Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia Journal of Psychosomatic Research 2002 53 3 737 740
63. Picchietti D., Winkelman J. W., Restless legs syndrome, periodic limb movements in sleep, and depression Sleep 2005 28 7 891 898 (Pubitemid 40993722)
64. Strhle A., Physical activity, exercise, depression and anxiety disorders Journal of Neural Transmission 2009 116 6 777 784
65. Washburn R. A., McAuley E., Katula J., Mihalko S. L., Boileau R. A., The physical activity scale for the elderly (PASE): evidence for validity Journal of Clinical Epidemiology 1999 52 7 643 651 (Pubitemid 29281660)
66. Koenig H. G., Westlund R. E., George L. K., Hughes D. C., Blazer D. G., Hybels C., Abbreviating the Duke Social Support Index for use in chronically ill elderly individuals Psychosomatics 1993 34 1 61 69 (Pubitemid 23052836)
67. Cohen J., Statistical Power Analysis for the Behavioral Sciences 1988 2nd Hillsdale, NJ, USA Lawrence Erlbaum Associates
68. Cohen D. L., Bloedon L. T., Rothman R. L., Farrar J. T., Galantino M. L., Volger S., Mayor C., Szapary P. O., Townsend R. R., Iyengar yoga versus enhanced usual care on blood pressure in patients with prehypertension to stage i hypertension: a randomized controlled trial Evidence-based Complementary and Alternative Medicine 2011 2011 8
69. Innes K. E., Bourguignon C., Taylor A. G., Risk indices associated with the insulin resistance syndrome, cardiovascular disease, and possible protection with yoga: a systematic review Journal of the American Board of Family Practice 2005 18 6 491 519 (Pubitemid 41823887)
70. Saptharishi L. G., Soudarssanane M. B., Thiruselvakumar D., Navasakthi D., Mathanraj S., Karthigeyan M., Sahai A., Community-based randomized controlled trial of non-pharmacological interventions in prevention and control of hypertension among young adults Indian Journal of Community Medicine 2009 34 4 329 334
71. Saletu M., Anderer P., Hgl B., Saletu-Zyhlarz G., Kunz A., Poewe W., Saletu B., Acute double-blind, placebo-controlled sleep laboratory and clinical follow-up studies with a combination treatment of rr-L-dopa and sr-L-dopa in restless legs syndrome Journal of Neural Transmission 2003 110 6 611 626 (Pubitemid 36683515)
72. Inoue Y., Kuroda K., Hirata K., Uchimura N., Kagimura T., Shimizu T., Long-term open-label study of pramipexole in patients with primary restless legs syndrome Journal of the Neurological Sciences 2010 294 1-2 62 66
73. Happe S., Klsch G., Saletu B., Zeitlhofer J., Treatment of idiopathic restless legs syndrome (RLS) with gabapentin Neurology 2001 57 9 1717 1719 (Pubitemid 33055499)
74. Bogan R. K., Fry J. M., Schmidt M. H., Carson S. W., Ritchie S. Y., Ropinirole in the treatment of patients with restless legs syndrome: a US-based randomized, double-blind, placebo-controlled clinical trial Mayo Clinic Proceedings 2006 81 1 17 27 (Pubitemid 43054313)
75. Partinen M., Hirvonen K., Jama L., Alakuijala A., Hublin C., Tamminen I., Koester J., Reess J., Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study-The PRELUDE study Sleep Medicine 2006 7 5 407 417 (Pubitemid 44130411)
76. McCormack P. L., Siddiqui M. A. A., Pramipexole: in restless legs syndrome CNS Drugs 2007 21 5 429 440
77. Garcia-Borreguero D., Larrosa O., De la Llave Y., Verger K., Masramon X., Hernandez G., Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study Neurology 2002 59 10 1573 1579 (Pubitemid 35387065)
78. Tison F., Crochard A., Léger D., Bouée S., Lainey E., El Hasnaoui A., Epidemiology of restless legs syndrome in French adultsa nationwide survey: the INSTANT Study Neurology 2005 65 2 239 246 (Pubitemid 41022368)
79. Allen R. P., Walters A. S., Montplaisir J., Hening W., Myers A., Bell T. J., Ferini-Strambi L., Restless legs syndrome prevalence and impact: REST general population study Archives of Internal Medicine 2005 165 11 1286 1292 (Pubitemid 40989594)
80. Allen R. P., Stillman P., Myers A. J., Physician-diagnosed restless legs syndrome in a large sample of primary medical care patients in western Europe: prevalence and characteristics Sleep Medicine 2010 11 1 31 37
81. Berger K., Luedemann J., Trenkwalder C., John U., Kessler C., Sex and the risk of restless legs syndrome in the general population Archives of Internal Medicine 2004 164 2 196 202 (Pubitemid 38140407)
82. Lee H. B., Hening W. A., Allen R. P., Earley C. J., Eaton W. W., Lyketsos C. G., Race and restless legs syndrome symptoms in an adult community sample in east Baltimore Sleep Medicine 2006 7 8 642 645 (Pubitemid 44815275)
83. Winkelman J. W., Finn L., Young T., Prevalence and correlates of restless legs syndrome symptoms in the Wisconsin Sleep Cohort Sleep Medicine 2006 7 7 545 552 (Pubitemid 44480745)
84. Hachul H., Bittencourt L. R. A., Andersen M. L., Haidar M. A., Baracat E. C., Tufik S., Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women International Journal of Gynecology and Obstetrics 2008 103 3 207 212
85. Polo-Kantola P., Erkkola R., Sleep and the menopause Journal of the British Menopause Society 2004 10 4 145 150 (Pubitemid 40057757)
86. Saletu-Zyhlarz G., Anderer P., Gruber G., Mandl M., Gruber D., Metka M., Huber J., Oettel M., Grser T., Hassan Abu-Bakr M., Grtzhofer E., Saletu B., Insomnia related to postmenopausal syndrome and hormone replacement therapy: sleep laboratory studies on baseline differences between patients and controls and double-blind, placebo-controlled investigations on the effects of a novel estrogen-progestogen combination (Climodien, Lafamme) versus estrogen alone Journal of Sleep Research 2003 12 3 239 254 (Pubitemid 37083022)
87. Weitz G., Elam M., Born J., Fehm H. L., Dodt C., Postmenopausal estrogen administration suppresses muscle sympathetic nerve activity Journal of Clinical Endocrinology and Metabolism 2001 86 1 344 348 (Pubitemid 32109816)
88. Rothdach A. J., Trenkwalder C., Haberstock J., Keil U., Berger K., Prevalence and risk factors of RLS in an elderly population: the MEMO study Neurology 2000 54 5 1064 1068 (Pubitemid 30151846)
89. Wesstrm J., Nilsson S., Sundstrm-Poromaa I., Ulfberg J., Restless legs syndrome among women: prevalence, co-morbidity and possible relationship to menopause Climacteric 2008 11 5 422 428
90. Ghorayeb I., Bioulac B., Scribans C., Tison F., Perceived severity of restless legs syndrome across the female life cycle Sleep Medicine 2008 9 7 799 802
91. McEwen B. S., Physiology and neurobiology of stress and adaptation: central role of the brain Physiological Reviews 2007 87 3 873 904 (Pubitemid 47086281)
92. McEwen B. S., Sleep deprivation as a neurobiologic and physiologic stressor: allostasis and allostatic load Metabolism 2006 55 supplement 1 S20 S23 (Pubitemid 44353567)
93. Brown R. P., Gerbarg P. L., Sudarshan Kriya yogic breathing in the treatment of stress, anxiety, and depression: part Ineurophysiologic model Journal of Alternative and Complementary Medicine 2005 11 1 189 201 (Pubitemid 40328134)
94. Innes K. E., Vincent H. K., Taylor A. G., Chronic stress and insulin resistance-related indices of cardiovascular disease risk, part I: neurophysiological responses and pathological sequelae Alternative Therapies in Health and Medicine 2007 13 4 46 52 (Pubitemid 351299282)
95. Innes K. E., Vincent H. K., Taylor A. G., Chronic stress and insulin resistance-related indices of cardiovascular disease risk, part 2: a potential role for mind-body therapies Alternative Therapies in Health and Medicine 2007 13 5 44 51 (Pubitemid 351299605)
96. Cohen D. L., Wintering N., Tolles V., Townsend R. R., Farrar J. T., Galantino M. L., Newberg A. B., Cerebral blood flow effects of yoga training: preliminary evaluation of 4 cases Journal of Alternative and Complementary Medicine 2009 15 1 9 14
97. Streeter C. C., Jensen J. E., Perlmutter R. M., Cabral H. J., Tian H., Terhune D. B., Ciraulo D. A., Renshaw P. F., Yoga Asana sessions increase brain GABA levels: a pilot study Journal of Alternative and Complementary Medicine 2007 13 4 419 426 (Pubitemid 46802346)
98. Kjaer T. W., Bertelsen C., Piccini P., Brooks D., Alving J., Lou H. C., Increased dopamine tone during meditation-induced change of consciousness Cognitive Brain Research 2002 13 2 255 259 (Pubitemid 34212051)
99. Leknes S., Tracey I., A common neurobiology for pain and pleasure Nature Reviews Neuroscience 2008 9 4 314 320 (Pubitemid 351430831)
100. Mignot E., Taheri S., Nishino S., Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders Nature Neuroscience 2002 5 1071 1075 (Pubitemid 35247202)
101. Goerendt I. K., Messa C., Lawrence A. D., Grasby P. M., Piccini P., Brooks D. J., Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study Brain 2003 126 2 312 325 (Pubitemid 36172738)
102. Scranton R., Cincotta A., Bromocriptine unique formulation of a dopamine agonist for the treatment of type 2 diabetes Expert Opinion on Pharmacotherapy 2010 11 2 269 279
103. Belavic J. M., A new treatment option for type 2 diabetes The Nurse Practitioner 2010 35 1 51 52
104. Lloyd K. G., Worms P., Neuropharmacological actions of GABA agonists: predictability for their clinical usefulness Advances in Biochemical Psychopharmacology 1981 29 59 67
105. Shiah I. S., Yatham L. N., GABA function in mood disorders: an update and critical review Life Sciences 1998 63 15 1289 1303 (Pubitemid 29369125)
106. Enna S. J., McCarson K. E., The role of GABA in the mediation and perception of pain Advances in Pharmacology 2006 54 1 27
107. Chouinard G., The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs Journal of Psychiatry and Neuroscience 2006 31 3 168 176 (Pubitemid 43954735)
108. Arnold L. M., Goldenberg D. L., Stanford S. B., Lalonde J. K., Sandhu H. S., Keck P. E., Welge J. A., Bishop F., Stanford K. E., Hess E. V., Hudson J. I., Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial Arthritis and Rheumatism 2007 56 4 1336 1344 (Pubitemid 46608659)
109. Baillie J. K., Power I., The mechanism of action of gabapentin in neuropathic pain Current Opinion in Investigational Drugs 2006 7 1 33 39 (Pubitemid 43115778)
110. Fulda S., Wetter T. C., Where dopamine meets opioids: a meta-analysis of the placebo effect in restless legs syndrome treatment studies Brain 2008 131, part 4 902 917 (Pubitemid 351499412)
111. Benes H., Walters A. S., Allen R. P., Hening W. A., Kohnen R., Definition of restless legs syndrome, how to diagnose it, and how to differentiate it from RLS mimics Movement Disorders 2007 22 supplement 18 S401 S408
112. Brindani F., Vitetta F., Gemignani F., Restless legs syndrome: differential diagnosis and management with pramipexole Clinical Interventions in Aging 2009 4 305 313
113. Hansen R. A., Song L., Moore C. G., Gilsenan A. W., Kim M. M., Calloway M. O., Murray M. D., Effect of ropinirole on sleep outcomes in patients with restless legs syndrome: meta-Analysis of pooled individual patient data from randomized controlled trials Pharmacotherapy 2009 29 3 255 262
114. Conti C. F., De Oliveira M. M., Andriolo R. B., Saconato H., Atallah A. N., Valbuza J. S., De Carvalho L. B. C., Do Prado G. F., Levodopa for idiopathic restless legs syndrome: evidence-based review Movement Disorders 2007 22 13 1943 1951 (Pubitemid 350134209)
115. Conti C. F., De Oliveira M. M., Valbuza J. S., Prado L. B. F., De Carvalho L. B. C., Prado G. F. D., Anticonvulsants to treat idiopathic restless legs syndrome: systematic review Arquivos de Neuro-Psiquiatria 2008 66 2 431 435 (Pubitemid 352030302)
116. Kushida C. A., Ropinirole for the treatment of restless legs syndrome Neuropsychiatric Disease and Treatment 2006 2 4 407 419 (Pubitemid 46321871)
117. Winkelman J. W., Redline S., Baldwin C. M., Resnick H. E., Newman A. B., Gottlieb D. J., Polysomnographic and health-related quality of life correlates of restless legs syndrome in the sleep heart health study Sleep 2009 32 6 772 778
118. Hornyak M., Kopasz M., Berger M., Riemann D., Voderholzer U., Impact of sleep-related complaints on depressive symptoms in patients with restless legs syndrome Journal of Clinical Psychiatry 2005 66 9 1139 1145 (Pubitemid 41442281)
119. Hening W., Walters A. S., Allen R. P., Montplaisir J., Myers A., Ferini-Strambi L., Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study Sleep Medicine 2004 5 3 237 246 (Pubitemid 38684217)