Restless legs syndrome: Evidence for nocturnal hypothalamic-pituitary- adrenal system activation

Movement Disorders

Volumn 25, Issue 8, 2010, Pages 1047-1052

  Schilling, Claudia ^a   Schredl, Michael ^a   Strobl, Philipp ^a   Deuschle, Michael ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Cardiovascular; Cortisol; HPA system; Polysomnography; Restless legs syndrome

Indexed keywords

HYDROCORTISONE;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CONTROL GROUP; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYDROCORTISONE URINE LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIMB DISEASE; MAJOR CLINICAL STUDY; MALE; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; RESTLESS LEGS SYNDROME; SLEEP DISORDER; URINALYSIS; URINARY EXCRETION; AGED; ANALYSIS OF VARIANCE; CARDIOVASCULAR DISEASES; CIRCADIAN RHYTHM; MIDDLE AGED; PHYSIOLOGY; PROCEDURES; SEX DIFFERENCE; STATISTICS; TIME; URINE;

ADULT; AGED; ANALYSIS OF VARIANCE; CARDIOVASCULAR DISEASES; CIRCADIAN RHYTHM; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; RESTLESS LEGS SYNDROME; SEX FACTORS; STATISTICS AS TOPIC; TIME FACTORS;

EID: 77953484531     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.23026     Document Type: Article

References (41)

1. Walters AS. Toward a better definition of the restless legs syndrome. Mov Disord 1995;10:634-642.
2. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisir J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-119.
3. Ulfberg J, Nystrom B, Carter N, Edling C. Prevalence of restless legs syndrome among men aged 18 to 64 years: an association with somatic disease and neuropsychiatric symptoms. Mov Disord 2001;16:1159-1163. (Pubitemid 36041234)
4. Ohayon MM, Roth T. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. J Psychosom Res 2002;53:547-554.
5. Phillips B, Hening W, Britz P, Mannino D. Prevalence and correlates of restless legs syndrome. Chest 2006;129:76-80.
6. Winkelman JW, Finn L, Young T. Prevalence and correlates of restless legs syndrome symptoms in the Wisconsin Sleep Cohort. Sleep Med 2006;7:545-552. (Pubitemid 44480745)
7. Winkelman JW, Shahar E, Sharief I, Gottlieb DJ. Associations of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study. Neurology 2008;70:35-42.
8. Walters AS, Rye DB. Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke. Sleep 2009;32:589-597.
9. Winkelman JW. The evoked heart rate response to periodic leg movements of sleep. Sleep 1999;22:575-580.
10. Sforza E, Nicolas A, Lavigne G, Gosselin A, Petit D, Montplaisir J. EEG and cardiac activation during periodic leg movements in sleep: support for a hierarchy of arousal responses. Neurology 1999;52:786-791. (Pubitemid 29120186)
11. Pennestri MH, Montplaisir J, Colombo R, Lavigne G, Lanfranchi PA. Nocturnal blood pressure changes in patients with restless legs syndrome. Neurology 2007;68:1213-1218. (Pubitemid 46608469)
12. Phillips B, Mannino DM. Do insomnia complaints cause hypertension or cardiovascular disease? J Clin Sleep Med 2007;3:489-494.
13. Schwartz S, McDowell Anderson W, Cole SR, Cornoni-Huntley J, Hays JC, Blazer D. Insomnia and heart disease: a review of epidemiologic studies. J Psychosom Res 1999;47:313-333.
14. Ayas NT, White DP, Manson JE, et al. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med 2003;163:205-209. (Pubitemid 36120188)
15. Mallon L, Broman JE, Hetta J. Sleep complaints predict coronary artery disease mortality in males: a 12-year follow-up study of a middle-aged Swedish population. J Intern Med 2002;251:207-216. (Pubitemid 34227184)
16. Schlesinger I, Erikh I, Avizohar O, Sprecher E, Yarnitsky D. Cardiovascular risk factors in restless legs syndrome. Mov Disord 2009;24:1587-1592.
17. Björntorp P, Rosmond R. Hypothalamic origin of the metabolic syndrome X. Ann NY Acad Sci 1999;892:297-307.
18. Chrousos GP. The role of stress and the hypothalamic-pituitary-adrenal axis in the pathogenesis of the metabolic syndrome: neuro-endocrine and target tissue-related causes. Int J Obes Relat Metab Disord 2000;24,S50-S55.
19. Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: epidemiology, biology and treatment. Arch Gen Psychiatry 1998;55:580-592.
20. Lett HS, Blumenthal JA, Babyak MA, et al. Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment. Psychosomatic Med 2004;66:315-325.
21. Vgontzas AN, Bixler EO, Lin HM, et al. Chronic insomnia is associated with nyctohermal activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J Clin Endocrinol Metab 2001;86:3787-3794.
22. Rodenbeck A, Huether G, Rüther E, Hajak G. Interactions between evening and nocturnal cortisol secretion and sleep parameters in patients with severe chronic primary insomnia. Neurosci Lett 2002;324:159-163. (Pubitemid 34460695)
23. Wetter TC, Collado-Seidel V, Oertel H, Uhr M, Yassouridis A, Trenkwalder C. Endocrine rhythms in patients with restless legs syndrome. J Neurol 2002;249:146-151. (Pubitemid 34143468)
24. Garcia-Borreguero D, Larrosa O, Granizo JJ, de la Llave Y, Hening WA. Circadian variation in neuroendocrine response to L-dopa in patients with restless legs syndrome. Sleep 2004;27:669-673. (Pubitemid 38823363)
25. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring for sleep stages in human subjects. Los Angeles: Brain Information Service, Brain Research Institute, UCLA; 1968.
26. The ASDA Atlas Task Force. EEG arousals: scoring rules and examples. Sleep 1992;15:174-184.
27. The ASDA Atlas Task Force. Recording and scoring leg movements. Sleep 1993;16:749-759.
28. Deuschle M, Schweiger U, Weber B, et al. Diurnal activity and pulsatility of the hypothalamus-pituitary-adrenal system in male depressed patients and healthy controls. J Clin Endocrinol Metab 1997;82:234-238. (Pubitemid 27021303)
29. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Intern Med 2000;160:2137-2141. (Pubitemid 30482720)
30. Gao X, Schwarzschild MA, Wang H, Ascherio A. Obesity and restless legs syndrome in men and women. Neurology 2009;72:1255-1261.
31. Piccietti D, Winkelman JW. Restless legs syndrome, periodic limb movements in sleep, and depression. Sleep 2005;28:891-898. (Pubitemid 40993722)
32. Holsboer F, von Bardeleben U, Steiger A. Effects of intravenous corticotropin-releasing hormone upon sleep-related growth hormone surge and sleep EEG in man. Neuroendocrinology 1988;48:32-38.
33. Vgontzas AN, Bixler EO, Wittman AM, et al. Middle-aged men show higher sensitivity of sleep to the arousing effects of corticotropin-releasing hormone than young men: clinical implications. J Clin Endocrinol Metab 2001;86:1489-1495.
34. Jarrett DB, Greenhouse JB, Thompson SB, McEachran A, Coble P, Kupfer DJ. Effect of nocturnal intravenous cannulation upon sleep-EEG measures. Biol Psychiatry 1984;19:1537-1550.
35. Vitiello MV, Larsen LH, Moe KE, Borson S, Schwartz RS, Prinz PN. Objective sleep quality of healthy older men and women is differentially disrupted by nighttime periodic blood sampling via indwelling catheter. Sleep 1996;19:304-311. (Pubitemid 26000339)
36. Späth-Schwalbe E, Gofferje M, Kern W, Born J, Fehm HL. Sleep disruption alters nocturnal ACTH and cortisol secretory patterns. Biol Psychiatry 1991;29:575-584.
37. Späth-Schwalbe E, Uthgenannt D, Voget G, Kern W, Born J, Fehm HL. Corticotropin-releasing hormone-induced adrenocorticotropin and cortisol secretion depends on sleep and wakefulness. J Clin Endocrinol Metab 1993;77:1170-1173. (Pubitemid 23345464)
38. Högl B. Circadian rhythms in RLS. Sleep Med 2006;7:209-210.
39. Vgontzas AN, Pejovic S, Zoumakis E, et al. Hypothalamic-pituitary-adrenal axis activity in obese men with and without sleep apnea: effects of continuous positive airway pressure therapy. J Clin Endocrinol Metab 2007;92:4199-4207. (Pubitemid 350074732)
40. Hening W, Walters AS, Allen RP, Montplaisir J, Myers A, Ferini-Strambi L. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study. Sleep Med 2004;5:237-246. (Pubitemid 38684217)
41. Allen RP, Walters AS, Montplaisir J, Hening W, Myers A, Bell TJ, Ferini-Strambi L. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 2005;165:1286-1292. (Pubitemid 40989594)