Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold

Journal of the American Chemical Society

Volumn 134, Issue 10, 2012, Pages 4654-4660

  Yoshidome, Tomofumi ^a   Endo, Masayuki ^b,c   Kashiwazaki, Gengo ^a   Hidaka, Kumi ^a   Bando, Toshikazu ^a   Sugiyama, Hiroshi ^a,b,c  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENTS; ATOMIC FORCE MICROSCOPIES (AFM); BASE PAIRS; CHLOROMETHYL; DNA ORIGAMIS; DOUBLE-STRANDED DNA (DS-DNA); FUNCTIONALIZED; GEL ELECTROPHORESIS; NANOSCAFFOLDS; NOVEL STRATEGIES; PYRROLE-IMIDAZOLE POLYAMIDES; SINGLE MOLECULE LEVEL; SINGLE-MOLECULE; SINGLE-MOLECULE OBSERVATION; STREPTAVIDIN; TARGET POSITION; TARGET SEQUENCES; TARGET SITES;

ALKYLATION; ATOMIC FORCE MICROSCOPY; DNA; ELECTROPHORESIS; GENE ENCODING; MOLECULES; PROTEINS; SCAFFOLDS;

DNA SEQUENCES;

(CHLOROMETHYL) 5 HYDROXY 1,2 DIHYDRO 3H BENZ[E]INDOLE; BIOTIN; DOUBLE STRANDED DNA; IMIDAZOLE; INDOLE; PYRROLE; STREPTAVIDIN; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMICAL STRUCTURE; DNA ALKYLATION; DNA DETERMINATION; DNA SEQUENCE; GEL ELECTROPHORESIS;

ALKYLATION; BASE SEQUENCE; DNA; IMIDAZOLES; MICROSCOPY, ATOMIC FORCE; NYLONS; PYRROLES;

EID: 84858259472     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja209023u     Document Type: Article

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