Extracellular signal-regulated kinase 2 signaling in the hippocampal dentate gyrus mediates the antidepressant effects of testosterone

Biological Psychiatry

Volumn 71, Issue 7, 2012, Pages 642-651

  Carrier, Nicole ^a   Kabbaj, Mohamed ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

17 estradiol; depression; ERK2; hippocampus; neurogenesis; testosterone

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ESTROGEN DERIVATIVE; HERPESVIRUS VECTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; SUCROSE; TESTOSTERONE;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; AROMATIZATION; ARTICLE; BRAIN NERVE CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FORCED SWIMMING TEST; GENE EXPRESSION; GONADECTOMY; HIPPOCAMPUS; HORMONE ACTION; MALE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TASTE PREFERENCE; TESTOSTERONE BLOOD LEVEL;

ANHEDONIA; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL PROLIFERATION; CELL SURVIVAL; CHOICE BEHAVIOR; DENTATE GYRUS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IMMOBILITY RESPONSE, TONIC; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MOTOR ACTIVITY; NEUROGENESIS; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RECEPTORS, GLUCOCORTICOID; TESTOSTERONE;

EID: 84858224466     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.11.028     Document Type: Article

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