HLA-G and NK receptor are expressed in psoriatic skin: A possible pathway for regulating infiltrating T cells?

American Journal of Pathology

Volumn 159, Issue 1, 2001, Pages 71-77

  Aractingi, Selim ^a   Briand, Nicola ^a   Le Danff, Caroline ^a   Viguier, Manuelle ^a   Bachelez, Hervé ^a   Michel, Laurence ^a   Dubertret, Louis ^a   Carosella, Edgardo D ^a  

^a HÔPITAL TENON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; GLYCOPROTEIN P 15095; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA G ANTIGEN; HLA-G ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; LILRB1 PROTEIN, HUMAN; MESSENGER RNA; NKTR PROTEIN, HUMAN;

ALTERNATIVE RNA SPLICING; ARTICLE; CD4+ T LYMPHOCYTE; FEMALE; GENETICS; HUMAN; MACROPHAGE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSORIASIS; REFERENCE VALUE; SKIN; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

ALTERNATIVE SPLICING; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; INTEGRIN ALPHAXBETA2; LYMPHOCYTES, TUMOR-INFILTRATING; MACROPHAGES; PSORIASIS; RECEPTORS, IMMUNOLOGIC; REFERENCE VALUES; RNA, MESSENGER; SKIN; T-LYMPHOCYTES;

EID: 0035403427     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61675-6     Document Type: Article

References (35)

1. Greaves MW, Weinstein GD: Treatment of psoriasis. N Engl J Med 1995, 332:581-588
2. Christophers E, Mrowietz U: The inflammatory infiltrate in psoriasis. Clin Dermatol 1995, 13:131-135
3. Strange P, Cooper KD, Hansen ER, Fisher G, Larsen JK, Fox D, Krag C, Voorhees JJ, Baadsgaard O: T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinocyte proliferation. J Invest Dermatol 1993, 101:695-700
4. Gilhar A, David M, Ullmann Y, Berkutski T, Kalish RS: T-lymphocyte dependence of psoriatic pathology in human psoriatic skin grafted to SCID mice. J Invest Dermatol 1997, 109:283-288
5. Wrone-Smith T, Nickoloff BJ: Dermal injection of immunocytes induces psoriasis. J Clin Invest 1996, 98:1878-1887
6. Nickoloff BJ, Wrone-Smith T: Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis. Am J Pathol 1999, 155:145-158
7. Griffiths CE, Powels A, Leonard J, Fry L, Baker BS, Valdimarsson H: Clearance of psoriasis with low dose cyclosporin. Br Med J 1986, 293:731-732
8. 389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat Med 1995, 1:442-447
9. Abrams JR, Lebwohl MG, Guzzo CA, Jegasothy BV, Goldfarb MT, Goffe BS, Menter A, Lowe NJ, Krueger G, Brown MJ, Weiner RS, Birkhofer MJ, Warner GL, Berry KK, Linsley PS, Krueger JG, Ochs HD, Kelley SL, Kang S: CTLA4Ig-mediated blockade of T-cell co-stimulation in patients with psoriasis vulgaris. J Clin Invest 1999, 103:1243-1252
10. Schlaak JF, Buslau M, Jocum W, Hermann E, Girndt M, Gallati H, Meyer zum Buschenfelde KH, Fleischer B: T cells involved in psoriasis vulgaris belong to the Th1 subset. J Invest Dermatol 1994, 102:145-149
11. Vogel U, Denecke B, Troyanovsky SM, Leube RE, Bottger EC: Transcriptional actuation of psoriasis-associated cytokeratin 17 by interferon-γ. Analysis of interferon-γ activation sites. Eur J Biochem 1995, 227:143-149
12. Nickoloff BJ, Wrone-Smith T, Bonish B, Porcelli S: Response of murine and normal human skin to injection of allogeneic blood derived psoriatic immunocytes. Arch Dermatol 1999, 135:546-552
13. Carosella ED, Rouas-Freiss N, Paul P, Dausset J: HLA-G: a tolerance molecule from the major histocompatibility complex. Immunol Today 1999, 20:60-62
14. Colonna M, Navarro F, Bellon T, Llano M, Garcia P, Samaridis J, Angman L, Ce la M, Lopez-Botet M: A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytoid cells J Exp Med 1997, 186:1809-1818
15. Cosman D, Fanger N, Borges L, Kubin M, Chin W, Peterson L, Hsu ML: A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 1997, 7:273-282
16. Rajagopalan S, Long EO: A human histocompatibility leucocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J Exp Med 1999, 189:1093-1099
17. Ponte M, Cantoni C, Biassoni R, Radori-Cappai A, Bentivoglio G, Vitale C, Bertone S, Moretta A, Moretta L, Mingari MC: Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor. Proc Natl Acad Sci USA 1999, 96:5674-5679
18. Rouas-Freiss N, Marchai R, Kieszenbaum M, Dausset J, Carosella ED: The α domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: is HLA-G the public ligand for natural killer inhibitory receptors? Proc Natl Acad Sci USA 1997, 94:5249-5254
19. Riteau B, Menier C, Khalil-Daher I, Dausset J, Rouas-Freiss N, Carosella ED: HLA-G inhibits the allogeneic proliferate response. J Reprod Immunol 1999, 43:203-211
20. Le Gal FA, Riteau B, Sedlik C, Khalil-Daher I, Menier C, Dausset J, Guillet JG, Carosella ED, Rouas-Freiss N: HLA-G mediated-inhibition of antigen-specific cytotoxic T lymphocytes. Int Immunity 1999, 11: 101-106
21. Yang Y, Chu W, Geraghty DE, Hunt JS: Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-γ. J Immunol 1996, 156:4224-4231
22. Yokoyama YM: The mother-child union: the case of missing self and protection of the fetus. Proc Natl Acad Sci USA 1997, 94:5998-6000
23. Paul P, Rouas-Freiss N, Khalil-Daher I, Moreau P, Riteau B, le Gal FA, Avirl MF, Dausset J, Guillet JG, Carosella E: HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci USA 1998, 95:4510-4515
24. Wagner SN, Rebmann V, Willers CP, Grosse-Wilde H, Goos M: Expression analysis of classic and non-classic HLA molecules before interferon alfa-2b treatment of melanoma. Lancet 2000, 356:220-221
25. Austin LM, Coven TR, Bhardwaj N, Steinman R, Krueger JG: Intraepidermal lymphocytes in psoriatic lymphocytes are activated GMP-17 (TIA 1)+CD8+CD3+ CTLs as determined by phenotypic analysis. J Cutan Pathol 1998, 25:78-88
26. Lee N, Malacko AR, Ishitani A, Chen M-C, Bajorath J, Marquart H, Geraghty DE: The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association. Immunity 1995, 3:591-600
27. Ulbrecht M, Rehberger B, Strobel I, Messer G, Kind P, Degitz K, Bieber T, Weiss EH: HLA-G: expression in human keratinocytes in vitro and in human skin in vivo. Eur J Immunol 1994, 24:176-180
28. Van den Oord JJ, de Wolf-Peeters C: Epithelium lining macrophages in psoriasis. Br J Dermatol 1994, 130:589-594
29. Boehncke WH, Wortmann S, Kaufman R, Mielke V Sterry W: A subset of macrophages located along the basement membrane (lining cells) is a characteristic histopathological feature of psoriasis. Am J Dermatopathol 1995, 17:139-144
30. Lefebvre S, Moreau P, Guiard V, Ibrahim EC, Adrian-Cabestre F, Menier C, Dausset J, Carosella ED, Paul P: Molecular mechanisms controlling constitutive and IFN inducible HLA-G expression in various cell types. J Reprod Immunol 1999, 43:213-224
31. Rouas-Freiss N, Marchal R, Menier C, Daussel J, Carosella ED: Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis. Proc Natl Acad Sci USA 1997, 94:11520-11525
32. Paul P, Cabestre FA, Le Gal FA, Khalil-Daher I, Le Danff C, Schmid M, Mercier S, Avril MF, Daussel J, Guillet JG, Carosella ED: Heterogeneity of HLA-G gene transcription and protein expression in malignant melanoma biopsies. Cancer Res 1999, 59:1954-1960
33. Nickoloff BJ: Skin innate immune system in psoriasis: friend or foe? J Clin Invest 1999, 104:1161-1164
34. Fournel S, Aguerre-Guirr M, Huc X, Lenfant F, Alam A, Toubert A, Bensoussan A, Le Bouteiller A: Soluble HLA-G1 triggers CD95/CD95 ligand mediated apoptosis in activated CD8+ cells by interacting with CD8. J Immunol 2000, 164:6100-6104
35. Saverino D, Fabbi M, Ghiotto F, Merlo A, Bruno S, Zarcone D, Tenca C, Tiso M, Santoro G, Anastasi G, Cosman D, Grossi CE, Ciccone E: The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions. J Immunol. 2000, 165:3742-3755