Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

Journal of Molecular Recognition

Volumn 25, Issue 3, 2012, Pages 147-154

  Nesspor, Thomas C ^a   Raju, T Shantha ^a   Chin, Chen Ni ^a   Vafa, Omid ^a   Brezski, Randall J ^a  

^a CENTOCOR INC   (United States)

Author keywords

avidity; Fc gamma receptor; glycosylation; imune effector function; monoclonal antibodies

Indexed keywords

FC RECEPTOR; GLYCOPEPTIDASE; IMMUNOGLOBULIN G; LEUKOCYTE ANTIGEN;

ANIMAL; ANTIBODY AFFINITY; ARTICLE; BINDING COMPETITION; CELL PROLIFERATION; CELL STRAIN HEK293; CHEMISTRY; GLYCOSYLATION; HUMAN; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE; PHAGOCYTOSIS; PHYSIOLOGY; PROTEIN BINDING; T LYMPHOCYTE;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS, CD; BINDING, COMPETITIVE; CELL PROLIFERATION; GLYCOSYLATION; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN G; MACROPHAGES; MICE; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PHAGOCYTOSIS; PROTEIN BINDING; RECEPTORS, IGG; T-LYMPHOCYTES;

EID: 84858176295     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.2155     Document Type: Article

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