Radon and lung cancer

Clinical Advances in Hematology and Oncology

Volumn 10, Issue 3, 2012, Pages 157-164

  Sethi, Tarsheen K ^a   El Ghamry, Moataz N ^a   Kloecker, Goetz H ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Carcinogenesis; Lung cancer; Radon; Tobacco

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CALCYCLIN; GLUTATHIONE TRANSFERASE; RADON; RADON 222; REACTIVE OXYGEN METABOLITE;

ADENOCARCINOMA; ALPHA RADIATION; ARTICLE; CARCINOGENESIS; CHROMOSOME BREAKAGE; DISEASE ASSOCIATION; DNA DAMAGE; GAS; HEALTH CARE PERSONNEL; HISTOPATHOLOGY; INFLAMMATION; LINEAR ENERGY TRANSFER; LUNG CANCER; LUNG FIBROSIS; MUTATION; RADIATION DETECTOR; RADIATION EXPOSURE; RADIOACTIVITY; RADIOISOTOPE DECAY; RISK FACTOR; SMOKING; SQUAMOUS CELL CARCINOMA; TOBACCO; TUMOR SUPPRESSOR GENE;

CARCINOGENS, ENVIRONMENTAL; CASE-CONTROL STUDIES; HUMANS; LUNG NEOPLASMS; NEOPLASMS; RADON; RISK FACTORS; SMOKING; UNITED STATES;

EID: 84858136732     PISSN: 15430790     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (69)

1. US Department of Health and Human Services. Surgeon General releases national health advisory on radon. Washington, DC: US Department of Health and Human Services; 2005. http://www.surgeongeneral.gov/pressreleases/ sg01132005.html. Accessed January 7, 2011.
2. Reuben SH. Reducing environmental cancer risk: what we can do now. In: 2008-2009 Annual Report: President's Cancer Panel, US Department Of Health and Human Services; 2010. http://deainfo.nci.nih.gov/advisory/pcp/annualReports/ pcp08-09rpt/PCP_Report_08-09_508.pdf. Accessed January 7, 2011.
3. Health Effects of Exposure to Radon: BEIR VI. Washington, D.C.: National Academy Press; 1999.
4. Marcinowski F LR, Yeager WM. National and regional distribution of airborne radon concentrations in US homes. Health Phys. 1994;66:699-707.
5. Generalised radon potential of United States: United States Geological Survey; 995. [updated October 13, 1995; cited June 8, 2011]; Available at: http://energy. cr.usgs.gov/radon/rnus.html.
6. Huda W. Review of Radiologic Physics. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2010:104-105.
7. Narayanan PK, Goodwin EH, Lehnert BE. Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res. 1997;57:3963-3971.
8. Jostes RF. Genetic, cytogenetic, and carcinogenic effects of radon: a review. Mutat Res. 1996;340:125-139.
9. Sawant SG, Randers-Pehrson G, Geard CR, Brenner DJ, Hall EJ. The bystander effect in radiation oncogenesis: I. Transformation in C3H 10T1/2 cells in vitro can be initiated in the unirradiated neighbors of irradiated cells. Radiat Res. 2001;155:397-401.
10. Brenner DJ, Little JB, Sachs RK. The bystander effect in radiation oncogenesis: II. A quantitative model. Radiat Res. 2001;155:402-408.
11. Brenner DJ, Sachs RK. Do low dose-rate bystander effects influence domestic radon risks? Int J Radiat Biol. 2002;78:593-604.
12. Azzam EI, De Toledo SM, Spitz DR, Little JB. Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alpha-particle-irradiated normal human fibroblast cultures. Cancer Res. 2002;62:5436-5442.
13. Breier R, Bohm R, Kopani M. Simulation of radiation damage to lung cells after exposure to radon decay products. Neuro Endocrinol Lett. 2006;27:86-90.
14. International Agency for Research on Cancer Monographs on the Evaluation of Carcinogenic Risks to Humans: Man-Made Mineral Fibres and Radon. Vol. 43. Lyon, France: IARC Press; 1988:33-171.
15. Hamza VZ, Mohankumar MN. Cytogenetic damage in human blood lymphocytes exposed in vitro to radon. Mutat Res. 2009;661:1-9.
16. Taylor JA, Watson MA, Devereux TR, Michels RY, Saccomanno G, Anderson M. p53 mutation hotspot in radon-associated lung cancer. Lancet. 1994;343:86-87.
17. Ruano-Ravina A, Faraldo-Valles MJ, Barros-Dios JM. Is there a specific mutation of p53 gene due to radon exposure? A systematic review. Int J Radiat Biol. 2009;85:614-621.
18. Ruano-Ravina A, Perez-Becerra R, Fraga M, Kelsey KT, Barros-Dios JM. Analysis of the relationship between p53 immunohistochemical expression and risk factors for lung cancer, with special emphasis on residential radon exposure. Ann Oncol. 2008;19:109-114.
19. Bastide K, Guilly MN, Bernaudin JF, et al. Molecular analysis of the Ink4a/ Rb1-Arf/Tp53 pathways in radon-induced rat lung tumors. Lung Cancer. 2009;63:348-353.
20. Xu NY, Zhang SP, Nie JH, Li JX, Tong J. Radon-induced proteomic profile of lung tissue in rats. J Toxicol Environ Health A. 2008;71:361-366.
21. US Department of Health and Human Services. Public Health Service, National Toxicology Program. Report on Carcinogens, 11th Edition. 2005. http://ntp.niehs. nih.gov/ntp/roc/eleventh/profiles/s097zird.pdf. Accessed January 7, 2011.
22. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Radon. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service; 1990.
23. Lubin JH, Boice JD Jr, Edling C, et al. Lung cancer in radon-exposed estimation of risk from indoor miners and exposure. J Natl Cancer Inst. 1995;87:817-827.
24. Lubin JH, Boice JD Jr, Edling C, et al. Lung Cancer and Radon: a Joint Analysis of 11 Underground Miner Studies. Bethesda, MD: National Cancer Institute; 1994. DHS Publ No. (NIH)94-3644.
25. Hornung R. Health effects in underground uranium miners. Occup Med. 2001;16:331-344.
26. Krewski D, Lubin JH, Zielinski JM, et al. Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies. Epidemiology. 2005;16:137-145.
27. Krewski D, Lubin JH, Zielinski JM, et al. A combined analysis of North American case-control studies of residential radon and lung cancer. J Toxicol Environ Health A. 2006;69:533-597.
28. Darby S, Hill D, Auvinen A, et al. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ. 2005;330:223.
29. Darby S, Hill D, Auvinen A, et al. Residential radon and lung cancer: detailed results of a collaborative analysis of individual data on 7,148 subjects with lung cancer and 14,208 subjects without lung cancer from 13 epidemiological studies in Europe. Scand J Work Environ Health. 2006;32:1-83.
30. Lubin JH, Wang ZY, Boice JD Jr, et al. Risk of lung cancer and residential radon in China: pooled results of two studies. Int J Cancer. 2004;109:132-137.
31. Pershagen G, Akerblom G, Axelson O, et al. Residential radon exposure and lung cancer in Sweden. N Engl J Med. 1994;330:159-164.
32. Field RW, Steck DJ, Smith BJ, et al. Residential radon gas exposure and lung cancer: the Iowa Radon Lung Cancer Study. Am J Epidemiol. 2000;151:1091-1102.
33. Thompson RE, Nelson DF, Popkin JH, Popkin Z. Case-control study of lung cancer risk from residential radon exposure in Worcester county, Massachusetts. Health Phys. 2008;94:228-241.
34. Wilcox HB, Al-Zoughool M, Garner MJ, et al. Case-control study of radon and lung cancer in New Jersey. Radiat Prot Dosimetry. 2008;128:169-179.
35. Mahaffey JA, Parkhurst MA, James AC, et al. Estimating past exposure to indoor radon from household glass. Health Phys. 1993;64:381-391.
36. Baysson H, Billon S, Laurier D, et al. Seasonal correction factors for estimating radon exposure in dwellings in France. Radiat Prot Dosimetry. 2003;104:245-252.
37. Sanders CL, Scott BR. Smoking and hormesis as confounding factors in radiation pulmonary carcinogenesis. Dose Response. 2008;6:53-79.
38. Brenner DJ, Doll R, Goodhead DT, et al. Cancer risks attributable to low doses of ionizing radiation: assessing what we really know. Proc Natl Acad Sci U S A. 2003;100:13761-13766.
39. Kreuzer M, Muller KM, Brachner A, et al. Histopathologic findings of lung carcinoma in German uranium miners. Cancer. 2000;89:2613-2621.
40. Land CE, Shimosato Y, Saccomanno G, et al. Radiation-associated lung cancer: a comparison of the histology of lung cancers in uranium miners and survivors of the atomic bombings of Hiroshima and Nagasaki. Radiat Res. 1993;134:234-243.
41. Saccomanno G, Auerbach O, Kuschner M, et al. A comparison between the localization of lung tumors in uranium miners and in nonminers from 1947 to 1991. Cancer. 1996;77:1278-1283.
42. Yao SX, Lubin JH, Qiao YL, et al. Exposure to radon progeny, tobacco use and lung cancer in a case-control study in southern China. Radiat Res. 1994;138:326-336.
43. Environmental Protection Agency. A Citizen's Guide to Radon. The Guide to Protecting Yourself and Your Family From Radon. Washington, DC; Environmental Protection Agency. http://www.epa.gov/radon/pubs/citguide.html. Accessed January 11, 2011.
44. Lagarde F, Axelsson G, Damber L, Mellander H, Nyberg F, Pershagen G. Residential radon and lung cancer among never-smokers in Sweden. Epidemiology. 2001;12:396-404.
45. Baias PF, Hofmann W, Winkler-Heil R, Cosma C, Duliu OG. Lung dosimetry for inhaled radon progeny in smokers. Radiat Prot Dosimetry. 2010;138:111-118.
46. Streffer C. The ICRP 2007 recommendations. Radiat Prot Dosimetry. 2007;127:2-7.
47. Bonner MR, Bennett WP, Xiong W, et al. Radon, secondhand smoke, glutathione-S-transferase M1 and lung cancer among women. Int J Cancer. 2006;119:1462-1467.
48. Archer VE, Renzetti AD, Doggett RS, Jarvis JQ, Colby TV. Chronic diffuse interstitial fibrosis of the lung in uranium miners. J Occup Environ Med. 1998;40:460-474.
49. Lubin JH, Linet MS, Boice JD, Jr, et al. Case-control study of childhood acute lymphoblastic leukemia and residential radon exposure. J Natl Cancer Inst. 1998;90:294-300.
50. Raaschou-Nielsen O. Indoor radon and childhood leukaemia. Radiat Prot Dosimetry. 2008;132:175-181.
51. Angell WJ. The US radon problem, policy, program and industry: achievements, challenges and strategies. Radiat Prot Dosimetry. 2008;130:8-13.
52. Zeeb H, Shannoun F. WHO Handbook on Indoor Radon: A Public Health Perspective. Geneva, Switzerland: World Health Organization; 2009. Accessed June 8, 2011.
53. Field RW. Environmental factors in cancer: radon. Rev Environ Health. 2010;25:23-31.
54. Henschel DB. Analysis of radon mitigation techniques used in existing US houses. Radiat Prot Dosimetry. 1994;56:21-27.
55. Environmental Protection Agency, State of Iowa, Department of Public Health. Radon Reduction Methods-A Homeowners Guide. 1995; http://www3. abe.iastate.edu/human_house/pm1350.asp. Accessed June 8, 2011.
56. Rahman NM, Tracy BL. Radon control systems in existing and new construction: a review. Radiat Prot Dosimetry. 2009;135:243-255.
57. Stigum H, Strand T, Magnus P. Should radon be reduced in homes? A costeffect analysis. Health Phys. 2003;84:227-235.
58. Coskeran T, Denman A, Phillips P, Tornberg R. A cost-effectiveness analysis of radon protection methods in domestic properties: a comparative case study in Brixworth, Northamptonshire, UK. J Environ Radioact. 2006;91:73-89.
59. Gray A, Read S, McGale P, Darby S. Lung cancer deaths from indoor radon and the cost effectiveness and potential of policies to reduce them. BMJ. 2009;338:a3110.
60. Mendez D, Alshanqeety O, Warner KE, Lantz PM, Courant PN. The impact of declining smoking on radon-related lung cancer in the United States. Am J Public Health. 2011;101:310-314.
61. Pass HI, Carbone DP, Johnson DH, et al. Principles & Practice of Lung cancer: the Official Reference Text of the IASLC. 4th ed. Philadelphia, PA: Wolters Kluver, Lipincott Williams & Wilkins; 2010.
62. Gonzalez CA, Riboli E. Diet and cancer prevention: contributions from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Eur J Cancer. 2010;46:2555-2562.
63. Hein MJ, Stayner LT, Lehman E, Dement JM. Follow-up study of chrysotile textile workers: cohort mortality and exposure-response. Occup Environ Med. 2007;64:616-625.
64. Hung RJ, McKay JD, Gaborieau V, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature. 2008;452:633-637.
65. Raaschou-Nielsen O, Andersen ZJ, Hvidberg M, et al. Lung cancer incidence and long-term exposure to air pollution from traffic. Environ Health Perspect. 2011;119:860-865.
66. Lubin JH, Boice JD Jr, Edling C, et al. Lung cancer in radon-exposed miners and estimation of risk from indoor exposure. J Natl Cancer Inst. 1995;87:817-827.
67. Darby SC, Whitley E, Howe GR, et al. Radon and cancers other than lung cancer in underground miners: a collaborative analysis of 11 studies. J Natl Cancer Inst. 1995;87:378-384.
68. Kreuzer M, Grosche B, Schnelzer M, Tschense A, Dufey F, Walsh L. Radon and risk of death from cancer and cardiovascular diseases in the German uranium miners cohort study: follow-up 1946-2003. Radiat Environ Biophys. 2010;49:177-185.
69. Wheeler BW, Allen J, Depledge MH, Curnow A. Radon and skin cancer in southwest England: an ecologic study. Epidemiology. 2012;23:44-52.