Losartan enhances the success of myoblast transplantation

Cell Transplantation

Volumn 21, Issue 1, 2012, Pages 139-152

  Fakhfakh, Raouia ^a   Lamarre, Yann ^a   Skuk, Daniel ^a   Tremblay, Jacques P ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Apoptosis; Duchenne muscular dystrophy (DMD); Inflammation; Myoblast transplantation; Transforming growth factor 1 (TGF 1)

Indexed keywords

DYSTROPHIN; LOSARTAN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL FUSION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; DOWN REGULATION; DUCHENNE MUSCULAR DYSTROPHY; HUMAN; HUMAN CELL; IMMUNODETECTION; IN VITRO STUDY; MOUSE; MYOBLAST TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CELLS, CULTURED; DYSTROPHIN; GRAFT SURVIVAL; HUMANS; LOSARTAN; MACROPHAGE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; MYOBLASTS; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 84858136707     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368911X576045     Document Type: Article

References (39)

1. Allen, R. E.; Boxhorn, L. K. inhibition of skeletal muscle satellite cell differentiation by transforming growth factor-beta. J. Cell. Physiol. 133(3):567-572; 1987.
2. Bedair, H. S.; Karthikeyan, T.; Quintero, A.; Li, Y.; Huard, J. Angiotensin II receptor blockade administered after injury improves muscle regeneration and decreases fibrosis in normal skeletal muscle. Am. J. Sports Med. 36(8):1548-1554; 2008.
3. Benabdallah, B. F.; Bouchentouf, M.; Rousseau, J.; Bigey, P.; Michaud, A.; Chapdelaine, P.; Scherman, D.; Tremblay, J. P. Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice. Cell Transplant. 17(3):337-350; 2008.
4. Bernasconi, P.; Torchiana, E.; Confalonieri, P.; Brugnoni, R.; Barresi, R.; Mora, M.; Cornelio, F.; Morandi, L.; Mantegazza, R. Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine. J. Clin. Invest. 96(2):1137-1144; 1995.
5. Blake, D. J.; Weir, A.; Newey, S. E.; Davies, K. E. Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiol. Rev. 82(2):291-329; 2002.
6. Border, W. A.; Ruoslahti, E. Transforming growth factor-beta in disease: The dark side of tissue repair. J. Clin. Invest. 90(1):1-7; 1992.
7. Brennan, T. J.; Edmondson, D. G.; Li, L.; Olson, E. N. Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. Proc. Natl. Acad. Sci. USA 88(9):3822-3826; 1991.
8. Chen, Y. W.; Nagaraju, K.; Bakay, M.; McIntyre, O.; Rawat, R.; Shi, R.; Hoffman, E. P. Early onset of inflammation and later involvement of TGFbeta in Duchenne muscular dystrophy. Neurology 65(6):826-834; 2005.
9. Cohn, R. D.; van Erp, C.; Habashi, J. P.; Soleimani, A. A.; Klein, E. C.; Lisi, M. T.; Gamradt, M.; ap Rhys, C. M.; Holm, T. M.; Loeys, B. L.; Ramirez, F.; Judge, D. P.; Ward, C. W.; Dietz, H. C. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat. Med. 13(2):204-210; 2007.
10. De Angelis, L.; Borghi, S.; Melchionna, R.; Berghella, L.; Baccarani-Contri, M.; Parise, F.; Ferrari, S.; Cossu, G. Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm. Proc. Natl. Acad. Sci. USA 95(21):12358-12363; 1998.
11. Dietz, H. C.; Cutting, G. R.; Pyeritz, R. E.; Maslen, C. L.; Sakai, L. Y.; Corson, G. M.; Puffenberger, E. G.; Hamosh, A.; Nanthakumar, E. J.; Curristin, S. M.; Stetten, G.; Meyers, D. A.; Francomano, C. A. Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. Nature 352(6333):337-339; 1991.
12. Fakhfakh, R.; Michaud, A.; Tremblay, J. P. Blocking the myostatin signal with a dominant negative receptor improves the success of human myoblast transplantation in dystrophic mice. Mol. Ther. 19(1):204-210; 2011.
13. Fan, Y.; Maley, M.; Beilharz, M.; Grounds, M. Rapid death of injected myoblasts in myoblast transfer therapy. Muscle Nerve 19(7):853-860; 1996.
14. Guerette, B.; Skuk, D.; Celestin, F.; Huard, C.; Tardif, F.; Asselin, I.; Roy, B.; Goulet, M.; Roy, R.; Entman, M.; Tremblay, J. P. Prevention by anti-LFA-1 of acute myoblast death following transplantation. J. Immunol. 159(5):2522-2531; 1997.
15. Habashi, J. P.; Judge, D. P.; Holm, T. M.; Cohn, R. D.; Loeys, B. L.; Cooper, T. K.; Myers, L.; Klein, E. C.; Liu, G. ; Calvi, C.; Podowski, M.; Neptune, E. R.; Halushka, M. K.; Bedja, D.; Gabrielson, K.; Rifkin, D. B.; Carta, L.; Ramirez, F.; Huso, D. L.; Dietz, H. C. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science 312(5770):117-121; 2006.
16. Iredale, J. P. Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ. J. Clin. Invest. 117(3):539-548; 2007.
17. Kinoshita, I.; Roy, R.; Dugre, F. J.; Gravel, C.; Roy, B.; Goulet, M.; Asselin, I.; Tremblay, J. P. Myoblast transplantation in monkeys: Control of immune response by FK506. J. Neuropathol. Exp. Neurol. 55(6):687-697; 1996.
18. Li, Y.; Foster, W.; Deasy, B. M.; Chan, Y.; Prisk, V.; Tang, Y.; Cummins, J.; Huard, J. Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: A key event in muscle fibrogenesis. Am. J. Pathol. 164(3):1007-1019; 2004.
19. Liu, L.; Qiu, H. B.; Yang, Y.; Wang, L.; Ding, H. M.; Li, H. P. Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat. Arch. Biochem. Biophys. 481(1):131-136; 2009.
20. Martin, J. F.; Li, L.; Olson, E. N. Repression of myogenin function by TGF-beta 1 is targeted at the basic helix-loop-helix motif and is independent of E2A products. J. Biol. Chem. 267(16):10956-10960; 1992.
21. Massague, J. TGF-beta signal transduction. Annu. Rev. Biochem. 67:753-791; 1998.
22. Massague, J.; Cheifetz, S.; Endo, T.; Nadal-Ginard, B. Type beta transforming growth factor is an inhibitor of myogenic differentiation. Proc. Natl. Acad. Sci. USA 83(21):8206-8210; 1986.
23. Morelli, A. E.; Zahorchak, A. F.; Larregina, A. T.; Colvin, B. L.; Logar, A. J.; Takayama, T.; Falo, L. D.; Thomson, A. W. Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation. Blood 98(5):1512-1523; 2001.
24. Mori, S.; Tokuyama, K. Variation in ACE activity affects myogenic differentiation in C2C12 cells. Biochem. Biophys. Res. Commun. 353(2):369-375; 2007.
25. Ohlendieck, K.; Ervasti, J. M.; Matsumura, K.; Kahl, S. D.; Leveille, C. J.; Campbell, K. P. Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle. Neuron 7(3):499-508; 1991.
26. Perry, R. L.; Rudnicki, M. A. Molecular mechanisms regulating myogenic determination and differentiation. Front. Biosci. 5:D750-767; 2000.
27. Roberts, A. B.; Anzano, M. A.; Lamb, L. C.; Smith, J. M.; Sporn, M. B. New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non-neoplastic tissues. Proc. Natl. Acad. Sci. USA 78(9): 5339-5343; 1981.
28. Rosenkranz, S. TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc. Res. 63(3):423-432; 2004.
29. Rousseau, J.; Dumont, N.; Lebel, C.; Quenneville, S. P.; Cote, C. H.; Frenette, J.; Tremblay, J. P. Dystrophin expression following the transplantation of normal muscle precursor cells protects mdx muscle from contraction-induced damage. Cell Transplant. 19(5):589-596; 2010.
30. Ruperez, M.; Lorenzo, O.; Blanco-Colio, L. M.; Esteban, V.; Egido, J.; Ruiz-Ortega, M. Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. Circulation 108(12):1499-1505; 2003.
31. Schaller, E.; Macfarlane, A. J.; Rupec, R. A.; Gordon, S.; McKnight, A. J.; Pfeffer, K. Inactivation of the F4/80 glycoprotein in the mouse germ line. Mol. Cell. Biol. 22(22): 8035-8043; 2002.
32. Sime, P. J.; Xing, Z.; Graham, F. L.; Csaky, K. G.; Gauldie, J. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J. Clin. Invest. 100(4):768-776; 1997.
33. Skuk, D.; Caron, N.; Goulet, M.; Roy, B.; Espinosa, F.; Tremblay, J. P. Dynamics of the early immune cellular reactions after myogenic cell transplantation. Cell Transplant. 11(7):671-681; 2002.
34. Skuk, D.; Tremblay, J. P. Myoblast transplantation: The current status of a potential therapeutic tool for myopathies. J. Muscle Res. Cell Motil. 24(4-6):285-300; 2003.
35. Takahashi, H. Dendritic cells and tumor specific immunity. Gan To Kagaku Ryoho 26(14):2121-2126; 1999.
36. Vaidya, T. B.; Rhodes, S. J.; Taparowsky, E. J.; Konieczny, S. F. Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1. Mol. Cell. Biol. 9(8):3576-3579; 1989.
37. Yang, H. H.; Kim, J. M.; Chum, E.; van Breemen, C.; Chung, A. W. Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome. J. Thorac. Cardiovasc. Surg. 140(2): 305-312 e302.
38. Zaccagnini, G.; Martelli, F.; Magenta, A.; Cencioni, C.; Fasanaro, P.; Nicoletti, C.; Biglioli, P.; Pelicci, P. G.; Capogrossi, M. C. p66(ShcA) and oxidative stress modulate myogenic differentiation and skeletal muscle regeneration after hind limb ischemia. J. Biol. Chem. 282(43): 31453-31459; 2007.
39. Ziai, F.; Nagano, H.; Kusaka, M.; Coito, A. J.; Troy, J. L.; Nadeau, K. C.; Rennke, H. G.; Tilney, N. L.; Brenner, B. M.; MacKenzie, H. S. Renal allograft protection with losartan in Fisher Lewis rats: Hemodynamics, macrophages, and cytokines. Kidney Int. 57(6):2618-2625; 2000.