Synthesis of heterocyclic N-(β-d-glucopyranosyl)carboxamides for inhibition of glycogen phosphorylase

Carbohydrate Research

Volumn 351, Issue , 2012, Pages 56-63

  Kónya, Bálint ^a   Docsa, Tibor ^a   Gergely, Pál ^a,b   Somsák, László ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

1,2,3 Triazole 4 carboxamide; Azide alkyne cycloaddition; Glycogen phosphorylase; Isoxazole 5 carboxamide; N ( d Glucopyranosyl) carboxamide; Nitrile oxide alkyne cycloaddition

Indexed keywords

1 ,3-DIPOLAR CYCLOADDITIONS; 1,2,3-TRIAZOLE-4-CARBOXAMIDE; AROMATIC AZIDES; AZIDE-ALKYNE CYCLOADDITION; CARBOXAMIDES; GLYCOGEN PHOSPHORYLASE; ISOXAZOLE-5-CARBOXAMIDE; PROPIOLIC ACID;

CYANIDES; CYCLOADDITION;

ACETYLENE;

1,2,3 TRIAZOLE DERIVATIVE; AMIDE; AMINE; GLYCOGEN PHOSPHORYLASE B; ISOXAZOLE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 1 (2 NAPHTHYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 1 (3,5 DIMETHYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 1 (4 RIFLUOROMETHYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 1 (4 TBUTYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 1 PHENYL 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 3 (2 NAPHTHYL) ISOXAZOLE 5 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 3 (INDOL 2 YL) ISOXAZOLE 5 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 3 (INDOL 3 YL) ISOXAZOLE 5 CARBOXAMIDE; N (2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 3 PHENYL ISOXAZOLE 5 CARBOXAMIDE; N (BET DEXTRO GLUCOPYRANOSYL) 3 (BENZO [B] FURAN 2 YL) ISOXAZOLE 5 CARBOXAMIDE; N (BET DEXTRO GLUCOPYRANOSYL) 3 PHENYL ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 1 (2 NAPHTHYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 1 (3,5 DIMETHYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 1 (4 TBUTYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 1 (4 TRIFLUOROMETHYL PHENYL) 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 1 PHENYL 1,2,3 TRIAZOLE 4 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 3 (2 NAPHTHYL) ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 3 (BENZO [B] THIOPHEN 2 YL) ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 3 (INDOL 2 YL) ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 3 (INDOL 3 YL) ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL) 3 ISOXAZOLE 5 CARBOXAMIDE; N (BETA DEXTRO GLUCOPYRANOSYL)CARBOXAMIDE; N PROPYNOYL 2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL AMINE; N PROPYNOYL 2,3,4,6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLAMINE; O PERACETYLATED N (BETA DEXTRO GLUCOPYRANOSYL) 1 SUBSTITUTED 1,2,3 TRIAZOLE 4 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CYCLOADDITION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; PRIORITY JOURNAL; SYNTHESIS;

ANIMALS; CHEMISTRY TECHNIQUES, SYNTHETIC; ENZYME INHIBITORS; GLYCOGEN PHOSPHORYLASE; HETEROCYCLIC COMPOUNDS; ISOXAZOLES; RABBITS; TRIAZOLES;

ORYCTOLAGUS CUNICULUS; TETRA;

EID: 84858079732     PISSN: 00086215     EISSN: 1873426X     Source Type: Journal    
DOI: 10.1016/j.carres.2012.01.020     Document Type: Article

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