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Volumn 16, Issue 1, 2012, Pages 68-71

Endoglin - A marker of vascular endothelial cell proliferation in cancer

Author keywords

Endoglin (CD105); Tumor angiogenesis; Vascular endothelial cells

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; ENDOGLIN; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD2 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

EID: 84858057536     PISSN: 14282526     EISSN: None     Source Type: Journal    
DOI: 10.5114/wo.2012.27340     Document Type: Review
Times cited : (30)

References (45)
  • 1
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley DM. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Development 1994; 8: 133-46.
    • (1994) Genes Development , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 2
    • 30144440059 scopus 로고    scopus 로고
    • Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders
    • Bertolino P, Deckers M, Lebrin F, ten Dijke P. Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders. Chest 2005; 128: 585-90.
    • (2005) Chest , vol.128 , pp. 585-590
    • Bertolino, P.1    Deckers, M.2    Lebrin, F.3    Ten Dijke, P.4
  • 4
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • DOI 10.1038/37284
    • Heldin C, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390: 465-71. (Pubitemid 28013118)
    • (1997) Nature , vol.390 , Issue.6659 , pp. 465-471
    • Heldin, C.-H.1    Miyazono, K.2    Ten, D.P.3
  • 5
    • 0025310515 scopus 로고
    • Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells
    • Gougos A, Letarte M. Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells. J Biol Chem 1990; 265: 8361-4.
    • (1990) J Biol Chem , vol.265 , pp. 8361-8364
    • Gougos, A.1    Letarte, M.2
  • 8
    • 42249110348 scopus 로고    scopus 로고
    • Endoglin (CD105): A marker of tumor vasculature and potential target for therapy
    • DOI 10.1158/1078-0432.CCR-07-4478
    • Dallas NA, Samuel S, Xia L, Fan F, Gray MJ, Lim SJ, Ellis LM. Endoglin (CD105): Amarker of tumor vasculature and potential target for therapy. Clin Cancer Res 2008; 14: 1931-7. (Pubitemid 351551101)
    • (2008) Clinical Cancer Research , vol.14 , Issue.7 , pp. 1931-1937
    • Dallas, N.A.1    Samuel, S.2    Xia, L.3    Fan, F.4    Gray, M.J.5    Lim, S.J.6    Ellis, L.M.7
  • 9
    • 0037113959 scopus 로고    scopus 로고
    • Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways
    • DOI 10.1074/jbc.M207160200
    • Sánchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabéu C. Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 2002; 277: 43799-808. (Pubitemid 36157800)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.46 , pp. 43799-43808
    • Sanchez-Elsner, T.1    Botella, L.M.2    Velasco, B.3    Langa, C.4    Bernabeu, C.5
  • 11
    • 0035860680 scopus 로고    scopus 로고
    • Identification of a critical Sp1 site within the endoglin promoter and its involvement in the transforming growth factor-beta stimulation
    • Botella LM, Sánchez-Elsner T, Rius C, Corbí A, Bernabéu C. Identification of a critical Sp1 site within the endoglin promoter and its involvement in the transforming growth factor-beta stimulation. J Biol Chem 2001; 276: 34486-34494.
    • (2001) J Biol Chem , vol.276 , pp. 34486-34494
    • Botella, L.M.1    Sánchez-Elsner, T.2    Rius, C.3    Corbí, A.4    Bernabéu, C.5
  • 13
    • 0028057726 scopus 로고
    • Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta
    • Yamashita H, Ichijo H, Grimsby S, Morén A, ten Dijke P, Miyazono K. Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta. J Biol Chem 1994; 269: 1995-2001. (Pubitemid 24035405)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.3 , pp. 1995-2001
    • Yamashita, H.1    Ichijo, H.2    Grimsby, S.3    Moren, A.4    Ten, D.P.5    Miyazono, K.6
  • 14
    • 0033534572 scopus 로고    scopus 로고
    • Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
    • Barbara NP, Wrana JL, Letarte M. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem 1999; 274: 584-94.
    • (1999) J Biol Chem , vol.274 , pp. 584-594
    • Barbara, N.P.1    Wrana, J.L.2    Letarte, M.3
  • 15
    • 0037047426 scopus 로고    scopus 로고
    • Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II
    • Guerrero-Esteo M, Sanchez-Elsner T, Letamendia A, Bernabeu C. Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II. J Biol Chem 2002; 277: 29197-209.
    • (2002) J Biol Chem , vol.277 , pp. 29197-29209
    • Guerrero-Esteo, M.1    Sanchez-Elsner, T.2    Letamendia, A.3    Bernabeu, C.4
  • 17
    • 0028170145 scopus 로고
    • Phosphorylation of the human-transforming-growth-factor-beta-binding protein endoglin
    • Lastres P, Martín-Perez J, Langa C, Bernabéu C. Phosphorylation of the human-transforming-growth-factor-beta-binding protein endoglin. Biochem J 1994; 301: 765-8. (Pubitemid 2118825)
    • (1994) Biochemical Journal , vol.301 , Issue.3 , pp. 765-768
    • Lastres, P.1    Martin-Perez, J.2    Langa, C.3    Bernabeu, C.4
  • 22
    • 2442700619 scopus 로고    scopus 로고
    • Endoglin regulates nitric oxide-dependent vasodilatation
    • Jerkic M, Rivas-Elena JV, Prieto M, et al. Endoglin regulates nitric oxide-dependent vasodilatation. FASEB J 2004; 18: 609-11.
    • (2004) FASEB J , vol.18 , pp. 609-611
    • Jerkic, M.1    Rivas-Elena, J.V.2    Prieto, M.3
  • 24
    • 0001421509 scopus 로고    scopus 로고
    • CD105 antagonizes the inhibitory signaling of transforming growth factor 1 on human vascular endothelial cells
    • Li C, Hampson IN, Hampson L, Kumar P, Bernabeu C, Kumar S. CD105 antagonizes the inhibitory signaling of transforming growth factor 1 on human vascular endothelial cells. FASEB J 1999; 14: 55-64.
    • (1999) FASEB J , vol.14 , pp. 55-64
    • Li, C.1    Hampson, I.N.2    Hampson, L.3    Kumar, P.4    Bernabeu, C.5    Kumar, S.6
  • 25
    • 4344652820 scopus 로고    scopus 로고
    • Highlights on endoglin (CD105): From basic findings towards clinical applications in human cancer
    • Fonsatti E, MaioM. Highlights on endoglin (CD105): from basic findings towards clinical applications in human cancer. J Translat Med 2004; 2: 18.
    • (2004) J Translat Med , vol.2 , pp. 18
    • Fonsatti, E.1    Maio, M.2
  • 26
    • 0028171579 scopus 로고
    • Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
    • McAllister KA, Grogg KM, Johnson DW et al. Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nat Genet 1994; 8: 345-51.
    • (1994) Nat Genet , vol.8 , pp. 345-351
    • McAllister, K.A.1    Grogg, K.M.2    Johnson, D.W.3
  • 27
    • 0038725471 scopus 로고    scopus 로고
    • CD105 is important for angiogenesis: Evidence and potential applications
    • DOI 10.1096/fj.02-0634rev
    • Duff SE, Li CH, Garland JM, Kumar S.CD105 is important for angiogenesis: evidence and potential applications. FASEB J 2003; 17: 984-92. (Pubitemid 36676386)
    • (2003) FASEB Journal , vol.17 , Issue.9 , pp. 984-992
    • Duff, S.E.1    Li, C.2    Garland, J.M.3    Kumar, S.4
  • 28
    • 0242708765 scopus 로고    scopus 로고
    • Endoglin (CD105): A powerful therapeutic target on tumor-associated angiogenetic blood vessels
    • Fonsatti E, Altomonte M, Nicotra MR, Natali PG, Maio M. Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels. Oncogene 2003; 22: 6557-63. (Pubitemid 37372335)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6557-6563
    • Fonsatti, E.1    Altomonte, M.2    Nicotra, M.R.3    Natali, P.G.4    Maio, M.5
  • 29
    • 18844413509 scopus 로고    scopus 로고
    • Endoglin is a better marker than CD31 in evaluation of angiogenesis in glioblastoma
    • Behrem S, Zarkowić K, Eskinja N, Jonjić N. Endoglin is a better marker than CD31 in evaluation of angiogenesis in glioblastoma. Croat Med J 2005; 46: 417-22. (Pubitemid 40686486)
    • (2005) Croatian Medical Journal , vol.46 , Issue.3 , pp. 417-422
    • Behrem, S.1    Zarkovic, K.2    Eskinja, N.3    Jonjic, N.4
  • 30
    • 33745727759 scopus 로고    scopus 로고
    • Endoglin expression is associated with poor oncologic outcome in oral and oropharyngeal carcinoma
    • DOI 10.1080/00016480500452558, PII G54MW7366M773J2L
    • Marioni G, Marino F, Giacomelli L, Staffieri C, Mariuzzi ML, Violino E, De Filippis C. Endoglin expression is associated with poor oncologic outcome in oral and oropharyngeal carcinoma. Acta Otolaryngol 2006; 126: 633-9. (Pubitemid 43995216)
    • (2006) Acta Oto-Laryngologica , vol.126 , Issue.6 , pp. 633-639
    • Marioni, G.1    Marino, F.2    Giacomelli, L.3    Staffieri, C.4    Livia, M.M.5    Violino, E.6    De Filippis, C.7
  • 31
    • 40549110569 scopus 로고    scopus 로고
    • Laryngeal carcinoma recurrence rate and disease-free interval are related to CD105 expression but not to vascular endothelial growth factor 2 (Flk-1/Kdr) expression
    • Marioni G, Giacomelli L, D'Alessandro E, Staffieri C, Guzzardo V, Staffieri A, Blandamura S. Laryngeal carcinoma recurrence rate and disease-free interval are related to CD105 expression but not to vascular endothelial growth factor 2 (Flk 1/Kdr) expression. Anticancer Res 2008; 28: 551-7. (Pubitemid 351362869)
    • (2008) Anticancer Research , vol.28 , Issue.1 B , pp. 551-557
    • Marioni, G.1    Giacomelli, L.2    D'Alessandro, E.3    Staffieri, C.4    Guzzardo, V.5    Staffieri, A.6    Blandamura, S.7
  • 33
    • 44849103617 scopus 로고    scopus 로고
    • Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype
    • DOI 10.1038/sj.onc.1211025, PII 1211025
    • Oxmann D, Held-Feindt J, Stark AM, Hattermann K, Yoneda T, Mentlein R. Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype. Oncogene 2008; 27: 3567-75. (Pubitemid 351793804)
    • (2008) Oncogene , vol.27 , Issue.25 , pp. 3567-3575
    • Oxmann, D.1    Held-Feindt, J.2    Stark, A.M.3    Hattermann, K.4    Yoneda, T.5    Mentlein, R.6
  • 37
    • 0346244039 scopus 로고    scopus 로고
    • Significance of CD 105 expression for tumour angiogenesis and prognosis in endometrial carcinomas
    • DOI 10.1111/j.1600-0463.2003.apm1111103.x
    • Salvensen HB, Gulluoglu MG, Stefansson I, Akslen LA. Significance of CD105 expression for tumour angiogenesis and prognosis in endometrial carcinomas. APMIS 2003; 111: 1011-8. (Pubitemid 37521894)
    • (2003) APMIS , vol.111 , Issue.11 , pp. 1011-1018
    • Salvesen, H.B.1    Gulluoglu, M.G.2    Stefansson, I.3    Akslen, L.A.4
  • 39
    • 4344658425 scopus 로고    scopus 로고
    • Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in colorectal cancer
    • DOI 10.1038/modpathol.3800034
    • Saad RS, Liu YL, Nathan G, Celebrezze J, Medich D, Silverman JF. Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in colorectal cancer. Modern Pathology 2004; 17: 197-203. (Pubitemid 41656516)
    • (2004) Modern Pathology , vol.17 , Issue.2 , pp. 197-203
    • Saad, R.S.1    Liu, Y.L.2    Nathan, G.3    Celebrezze, J.4    Medich, D.5    Silverman, J.F.6
  • 41
    • 33745068191 scopus 로고    scopus 로고
    • Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinoma
    • Yang L, Lu W, Huang G, Wang W. Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinoma. BMC Cancer 2006; 6: 110.
    • (2006) BMC Cancer , vol.6 , pp. 110
    • Yang, L.1    Lu, W.2    Huang, G.3    Wang, W.4
  • 42
    • 40949088879 scopus 로고    scopus 로고
    • Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer
    • Karam JA, Svatek RS, Karakiewicz PI, Gallina A, Roehrborn CG, Slawin KM, Shariat SF. Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer. Clin Cancer Res 2007; 14: 1418-22.
    • (2007) Clin Cancer Res , vol.14 , pp. 1418-1422
    • Karam, J.A.1    Svatek, R.S.2    Karakiewicz, P.I.3    Gallina, A.4    Roehrborn, C.G.5    Slawin, K.M.6    Shariat, S.F.7
  • 44
    • 0034907326 scopus 로고    scopus 로고
    • Association of serum endoglin with metastasis in patients with colorectal, breast, and other solid tumors, and suppressive effect of chemotherapy on the serum endoglin
    • Takahashi N, Kawanishi-Tabata R, Haba A, Tabata M, Haruta Y, Tsai H, Seon BK. Association of serum endoglin with metastasis in patients with colorectal, breast, and other solid tumors, and suppressive effect of chemotherapy on the serum endoglin. Clin Cancer Res 2001; 7: 524-32. (Pubitemid 32707974)
    • (2001) Clinical Cancer Research , vol.7 , Issue.3 , pp. 524-532
    • Takahashi, N.1    Kawanishi-Tabata, R.2    Haba, A.3    Tabata, M.4    Haruta, Y.5    Tsai, H.6    Seon, B.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.