Expression of NF-κB and downstream antioxidant genes in skeletal muscle of hibernating ground squirrels, Spermophilus tridecemlineatus

Cell Biochemistry and Function

Volumn 30, Issue 2, 2012, Pages 166-174

  Allan, Marcus E ^a   Storey, Kenneth B ^a  

^a CARLETON UNIVERSITY   (Canada)

Author keywords

Heme oxygenase; Hibernation; I B ; Mn dependent superoxide dismutase; NF B; Torpor arousal

Indexed keywords

ANTIOXIDANT; DNA; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PROTEIN P50; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ARTICLE; DISSOCIATION; DNA BINDING; DOWNSTREAM PROCESSING; GENE ACTIVATION; GENE EXPRESSION; HIBERNATION; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE; SPERMOPHILUS TRIDECEMLINEATUS; SQUIRREL;

ANIMALS; ANTIOXIDANTS; HEME OXYGENASE (DECYCLIZING); HIBERNATION; MUSCLE, SKELETAL; NF-KAPPA B; SCIURIDAE; SUPEROXIDE DISMUTASE; UP-REGULATION;

MAMMALIA; SPERMOPHILUS; SPERMOPHILUS TRIDECEMLINEATUS;

EID: 84858005971     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1832     Document Type: Article

References (44)

1. Storey KB. Regulation of liver metabolism by enzyme phosphorylation during mammalian hibernation. J Biol Chem 1987; 162: 1670-1673.
2. Wang CHI, Lee TF. Torpor and hibernation in mammals: metabolic, physiological and biochemical adaptations. In Handbook of Physiology: Environmental Physiology. Fregley MJ, Blatteis CM (eds.). Oxford University Press: New York, 1996; 507-532.
3. Storey KB. Out cold: biochemical regulation of mammalian hibernation. Gerontology 2010; 56: 220-230.
4. Storey KB, Storey JM. Tribute to P.L. Lutz: putting life on 'pause'-molecular regulation of hypometabolism. J Exp Biol 2007; 210: 1700-1714.
5. Hermes-Lima M, Zenteno-Savín T. Animal response to drastic changes in oxygen availability and physiological oxidative stress. Comp Biochem Physiol C 2002; 133: 537-556.
6. Muleme HM, Walpole AC, Staples JF. Mitochondrial metabolism in hibernation: metabolic suppression, temperature effects, and substrate preferences. Physiol Biochem Zool 2006; 79: 474-483.
7. Buzadzic B, Spasic M, Saicic ZS, Radojicic R, Petrovic VM, Halliwell B. Antioxidant defences in the ground squirrel Citellus citellus. Free Radic Biol Med 1990; 9: 407-413.
8. Carey HV, Andrews MT, Martin SL. Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature. Physiol Rev 2003; 83: 1153-1181.
9. Wang Y, Yamamoto S, Miyakawa A, Sakurai T, Ibaraki K, Terakawa S. Intravital oxygen radical imaging in normal and ischemic rat cortex. Neurosurgery 2010; 67: 118-127.
10. Ma YL, Zhu X, Rivera PM, et al. Absence of cellular stress in brain after hypoxia induced by arousal from hibernation in arctic ground squirrels. Am J Physiol 2005; 289: R1297-R1306.
11. Frerichs KU, Kennedy C, Sokoloff L, Hallenbeck JM. Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia". J Cereb Blood Flow Metab 1994; 14: 193-205.
12. Carey HV, Frank CL, Seifert JP. Hibernation induces oxidative stress and activation of NK-κB in ground squirrel intestine. J Comp Physiol B 2000; 170: 551-559.
13. Morin P Jr, Ni Z, McMullen DC, Storey KB. Expression of Nrf2 and its downstream gene targets in hibernating 13-lined ground squirrels, Spermophilus tridecemlineatus. Mol Cell Biochem 2008; 312: 121-129.
14. Ni Z, Storey KB. Heme oxygenase expression and Nrf2 signaling during hibernation in ground squirrels. Can J Pharmacol 2010; 88: 379-387.
15. Orr AL, Lohse LA, Drew KL, Hermes-Lima M. Physiological oxidative stress after arousal from hibernation in Arctic ground squirrel. Comp Biochem Physiol A 2009; 153: 213-221.
16. Carey HV, Rhoads CA, Aw TY. Hibernation induces glutathione redox imbalance in ground squirrel intestine. J Comp Physiol B 2003; 173: 269-276.
17. Drew KL, Tøien Ø, Rivera PM, Smith MA, Perry G, Rice ME. Role of the antioxidant ascorbate in hibernation and warming from hibernation. Comp Biochem Physiol C 2002; 133: 483-492.
18. MacDonald JA, Storey KB. Mitogen-activated protein kinases and selected downstream targets display organ-specific responses in the hibernating ground squirrel. Int J Biochem Cell Biol 2005; 37: 679-691.
19. Morin P Jr, Storey KB. Antioxidant defense in hibernation: cloning and expression of peroxiredoxins from hibernating ground squirrels, Spermophilus tridecemlineatus. Arch Biochem Biophys 2007; 461: 59-65.
20. Petrović VM, Saicić Z, Milić B, Spasić M, Radojicić R. Distribution of superoxide dismutase in the ground squirrel (Citellus citellus): effect of hibernation and arousal. Comp Biochem Physiol B 1983; 75: 699-700.
21. Li H, Malhotra S, Kumar A. Nuclear factor-κB signaling in skeletal muscle atrophy. J Mol Med 2008; 86: 1113-1126.
22. Ali S, Mann DA. Signal transduction via the NF-κB pathway: a targeted treatment modality for infection, inflammation and repair. Cell Biochem Funct 2004; 22: 67-79.
23. McMullen DC, Hallenbeck JM. Regulation of Akt during torpor in the hibernating ground squirrel, Ictidomys tridecemlineatus. J Comp Physiol B 2010; 180: 927-934.
24. Tessier SN, Storey KB. Expression of myocyte enhancer factor-2 and downstream genes in ground squirrel skeletal muscle during hibernation. Mol Cell Biochem 2010; 344: 151-162. doi:10.1007/s11010-010-0538-y.
25. Mamady H, Storey KB. Up-regulation of the endoplasmic reticulum molecular chaperone GRP78 during hibernation in thirteen-lined ground squirrels. Mol Cell Biochem 2006; 292: 89-98.
26. Häcker H, Karin M. Regulation of function of IKK and IKK related kinases. Sci STKE 2006; 357: re13.
27. Dark J, Miller DR. Metabolic fuel privation in hibernating and awake ground squirrels. Physiol Behav 1998; 63: 59-65.
28. Bar-Shai M, Carmeli E, Ljubuncic P, Reznick AZ. Exercise of immobilization in aging animals: the involvement of oxidative stress and NF-κB activation. Free Radic Biol Med 2008; 44: 202-214.
29. Hasselgren PO. Transcription factors and nuclear cofactors in muscle wasting. In Yearbook of Intensive Care and Emergency Medicine, Vol. 2007. Vincent JL (ed.). Springer; New York, 2007; 229-237.
30. Ji LL, Gomez-Cabrera M, Vina J. Role of nuclear factor κB and mitogen-activated protein kinase signaling in exercise-induced antioxidant enzyme adaptation. Appl Physiol Nutr Metab 2007; 32: 930-935.
31. Dejardin E. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem Pharmacol 2006; 72: 1161-1179.
32. Ten RM, Paya CV, Israel N, et al. The characterization of the promoter of the gene encoding the p50 subunit of NF-κB indicates that it participates in its own regulation. EMBO J 1992; 11: 195-203.
33. Cogswell PC, Scheinman RI, Baldwin AS, Jr. Promoter of human NF-κB p50/p105 gene. Regulation of NF-κB subunits and by c-REL. J Immunol 1993; 150: 2794-2804.
34. Ueberla K, Lu YC, Chung E, Haseltin WA. The NF-κB p65 promotor. J AIDS Res 1993; 6: 227-230.
35. Hoffmann A, Levchenko A, Scott ML, Baltimore D. The IκB-NF-κB signaling module: temporal control selective gene activation. Science 2002; 298: 1241-1245.
36. Scott ML, Fujita T, Liou H, Nolan GP, Baltimore D. The p65 subunit of NF-κB regulates IκB by two distinct mechanisms. Genes Dev 1993; 7: 1266-1276.
37. Kiningham KK, Cardoze ZA, Cook C, et al. All trans-retinoic acid induces manganese superoxide dismutase in human neruoblastoma through NF-κB. Free Radic Biol Med 2008; 44: 1610-1616.
38. Lin CC, Chiang LL, Lin CH, et al. Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-κB pathways in human lung epithelial cells. Eur J Pharmacol 2007; 560: 101-109.
39. Morin P, Jr, Dubuc A, Storey KB. Differential expression of microRNA species in organs of hibernating ground squirrels: a role in translational suppression during torpor. Biochim Biophys Acta 2008; 1779: 628-633.
40. Morin P, Storey KB. Mammalian hibernation: differential gene expression and novel application of epigenetic controls. Int J Dev Biol 2009; 53: 433-442.
41. Guo Y, Xiao P, Lei S, et al. How is mRNA expression predictive of protein expression? A correlation study on human circulating monocytes. Acta Biochim Biophys Sin 2008; 40: 426-436.
42. Pan P, van Breukelen F. Preference of IRES-mediated initiation of translation during hibernation in golden-mantled ground squirrels, Spermophilus lateralis. Am J Physiol 2011; 301: R370-R377.
43. Van Breukelen F, Martin SL. Translational initiation is uncoupled from elongation at 18°C during mammalian hibernation. Am J Physiol 2001; 281: R1374-R1379.
44. Van Breukelen F, Martin SL. Reversible depression of transcription during hibernation. J Comp Physiol B 2002; 172: 355-361.