Effects of long-term exposure to low levels of organophosphorous pesticides and their mixture on altered antioxidative defense mechanisms and lipid peroxidation in rat liver

Cell Biochemistry and Function

Volumn 30, Issue 2, 2012, Pages 122-128

  Yang, Jindan ^a   Cao, Jie ^a,b   Sun, Xiaowei ^a   Feng, Zhijing ^a   Hao, Dongfang ^a   Zhao, Xiujuan ^a   Sun, Changhao ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Zhenjiang Energy Saving Center   (China)

Author keywords

Antioxidant enzyme; Lipid peroxidation; Liver; Organophosphorous pesticides; Rats

Indexed keywords

ACEPHATE; ANTIOXIDANT; CATALASE; DICHLORVOS; DIMETHOATE; DRINKING WATER; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PHORATE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; CLINICAL EVALUATION; CONTROLLED STUDY; ENZYME ACTIVITY; EXPERIMENTAL RAT; LIPID PEROXIDATION; LIVER; LONG TERM EXPOSURE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; CATALASE; ENVIRONMENTAL EXPOSURE; GLUTATHIONE PEROXIDASE; HUMANS; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; PESTICIDES; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TIME;

RATTUS;

EID: 84858002821     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1825     Document Type: Article

References (32)

1. Joshi AK, Rajini PS. Reversible hyperglycemia in rats following acute exposure to acephate and organophosphorus insecticide: role of gluconeogenesis. Toxicol 2009; 257: 40-45.
2. Yarsan E, Cakir O. Effects of dichlorvos on lipid peroxidation in mice on subacute and subchronic periods. Pestic Biochem Physiol 2006; 86: 106-109.
3. Peter JV, Cherian AM. Organic insecticides. Anaesth Intensive Care 2000; 28: 11-21.
4. Moser VC, Casey M, Hamm A, Carter WH, Jr, Simmons JE, Gennings C. Neurotoxicological and Statistical Analyses of a Mixture of Five Organophosphorus Pesticides Using a Ray Design. Toxicol Sci 2005; 86(1): 101-115.
5. Ecobichon DJ. Toxic effects of pesticides. In Casarett and Doull's Toxicology, Klaassen CD, Amdur MO, Doull J (eds). McGraw-Hill: New York, 1996; 643-689.
6. Nostrandt AC, Padilla S, Moser VC. The relationship of oral chlorpyrifos effects on behavior, cholinesterase inhibition, and muscarinic receptor density in rat. Pharmacol Biochem Behav 1997; 58: 15-23.
7. Gupta J, Datta C, Sarkar A, Sengupta D. Effect of malathion on antioxidant defence system in human fetus-an in vitro study. Indian J Exp Biol 1996; 30: 352.
8. Bagchi D, Bagchi M, Hassoun EA, Stohs SJ. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 1995; 104: 129-140.
9. Ning YH, Liu XF, Xue YB, Guan SZ, Liu GZ. Effect of acephate on the capability of anti-oxidizing in testis of male rats. Chinese Journal of Ningxia Medical College 2008; 30(6): 726-728.
10. Celik I, Suzek H. Effects of subacute exposure of dichlorvos at sublethal dosages on erythrocyte and tissue antioxidant defense systems and lipid peroxidation in rats. Ecotoxicol Environ Saf 2009; 72: 905-908.
11. Cohen SD. Mechanisms of toxicological interactions involving organophosphate insecticides. Toxicol Sci 1984; 4: 315-324.
12. Casida JE, Baron RL, Eto M, Engel JL. Potentiation and neurotoxicity induced by certain organophosphates. Biochem Pharmacol 1963; 12: 73-78.
13. Tuzmen N, Candan N, Kaya E, Demiryas N. Biochemical effects of chlorpyrifos and deltamethrin on altered antioxidative defense mechanisms and lipid peroxidation in rat liver. Cell Biochem Funct 2008; 26: 119-124.
14. Ender Y, Onder C. Effects of dichlorvos on lipid peroxidation in mice on subacute and subchronic periods. Pest Biochem Physiol 2006; 86: 106-109.
15. Bebe FN, Panemangalore M. Exposure to lowdoses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats. J Environ Sci Heal B 2003; 38: 349-363.
16. Panemangalore M, Bebe FN. Dermal exposure to pesticides modifies antioxidant enzymes in tissues of rats. J Environ Sci Heal B 2000; 35: 399-416.
17. Gutteridge JM. Lipid peroxidations and antioxidants as biomarkers of tissue damage. Clin Chem 1995; 41: 1819-1828.
18. Kehrer JP. Free radicals as mediators of tissue injury and disease. Crit Rev Toxicol 1993; 23: 21-48.
19. Sanjukta D, Pubali D, Aniruddha M, Santinath G. Influence of polyphenolic extracts from Enydra fluctuans on oxidative stress induced by acephate in rats. Food Chem Toxicol 2010; 48: 2766-2771.
20. Akhgari M, Abdollahi M, Kebryaeezadeh A, Hosseini R, Sabzevari O. Biochemical evidence for free radical-induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Hum Exp Toxicol 2003; 22: 205-211.
21. Shadnia S, Azizi E, Hosseini R, et al. Evaluation of oxidative stress and genotoxicity in organophosphorus insecticide formulators. Hum Exp Toxicol 2005; 24: 439-445.
22. Dowla HA, Panemangalore M, Byers ME. Comparative inhibition of enzymes of human erythrocytes and plasma in vitro by agricultural chemicals. Arch Environ Contam Toxicol 1996; 31: 107-114.
23. Pedrajas JR, Peinado J, Lopez-Barea J. Oxidative stress in fish exposed to model xenobiotics. Oxidatively modified forms of Cu, Zn-superoxide dismutase as potential biomarkers. Chem Biol Interact 1995; 98: 267-282.
24. Gromov LA, Seredi PI, Syrovatskaia LP, Ovinova GV, Filenenko MA. Free radical mechanisms of memory disorders of toxic origin and experimental therapy of the condition. Patol Fiziol Eksp Ter 1993; 4: 24-26.
25. Altuntas I, Delibas N, Sutcu R. The effects of organophosphate insecticide methidathion on lipid peroxidation and anti-oxidant enzymes in rat erythrocytes: role of vitamins E and C. Hum Exp Toxicol 2002; 21: 681-685.
26. Khan SM, Sobti RC, Kataria L. Pesticide-induced alteration in mice hepato-oxidative status and protective effects of black tea extract. Clin Chim Acta 2005; 358: 131-138.
27. Bebe FN, Panemangalore M. Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats. J Environ Sci Health B 2003; 38: 349-363.
28. Gultekin F, Ozturk M, Akdogan M. The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes(in vitro). Arch Toxicol 2000; 74: 533-538.
29. Khan SM, Kour G. Subacute oral toxicity of chlorpyriphos and protective effect of green tea extract. Pest Biochem Physiol 2007; 89: 118-123.
30. Reffstrup TK. Combined actions of pesticide in food. The Danish Veterinary and Food Administration, Fodevarerapport 2002; 19: 6-9.
31. Groten JP, Butler W, Feron VJ, Kozianowski G, Renwick AG, Walker R. An analysis of the possibility for health implications of joint actions and interactions between food additives. Regul Toxicol Pharmacol 2000; 31: 77-91.