Gene deletion of nos2 protects against manganese-induced neurological dysfunction in juvenile mice

Toxicological Sciences

Volumn 126, Issue 1, 2012, Pages 183-192

  Streifel, Karin M ^a   Moreno, Julie A ^a   Hanneman, William H ^a   Legare, Marie E ^a   Tjalkens, Ronald B ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

Author keywords

3 nitrotyrosine; Astrocyte; Inducible nitric oxide synthase; Manganese; Microglia

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 3 NITROTYROSINE; CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOCORTIN 5; MANGANESE CHLORIDE; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BASAL GANGLION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; GENE DELETION; GENOTYPE; GLIA; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; JUVENILE ANIMAL; MALE; MICROGLIA; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTOXICITY; NITROSATIVE STRESS; NONHUMAN; PROTEIN EXPRESSION;

MUS;

EID: 84857967628     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr335     Document Type: Article

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