In vitro α-amylase inhibition and antioxidant activities of methanolic extract of Amaranthus caudatus Linn

Oman Medical Journal

Volumn 26, Issue 3, 2011, Pages 166-170

  Ashok, Kumar Bs ^a   Lakshman, K ^b   Jayaveera, Kn ^c   Sheshadri Shekar, D ^a   Narayan Swamy, V B ^d   Khan, Saleemulla ^e   Velumurga, C ^a  

^a Sri KV College of Pharmacy   (India)

^b PES COLLEGE OF PHARMACY   (India)

^c JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^d Karavali College of Pharmacy   (India)

^e MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

amylase inhibition; Amaranthus caudatus; Antioxidant activity; Superoxide dismutase

Indexed keywords

EID: 84857953510     PISSN: 1999768X     EISSN: 20705204     Source Type: Journal    
DOI: 10.5001/omj.2011.40     Document Type: Article

References (39)

1. Rastrelli L, Pizza C, Saturnino P, Schettino O, Dini A. Isolation and characterization of Amaranthin, a lactin present in seeds of Amaranthus caudatus that recognizes the T-antigen. J Agric Food Chem 1995;43:904-909.
2. Haile yineger, Ensermu Kelbessa, Tamrat Bekele, Ermias Lulekal. Plants used in Traditional Management of Human Ailments at Bale Mountains National Park. 2008.
3. Vanila D, Ghanthikumar S, Manickam VS. Ethnomedicinal uses of plants in the plains area of the Tirunelveli-District. Tamilnadu, India, Ethnobotonical leaflets. 2008; 12: 1198-1205.
4. Khare CP. Indian Medicinal Plants, an Illustrated Dictionary, Springer, 2007;41.
5. Kabiri N, Asgary S, Madani H, Mahzouni P. Effect of Amaranthus caudatus extract and lovastatin on atherosclerosis in hypercholesterolemic rabbits. J Medicinal Plants Res. 2010;4(5):355-361.
6. Kumar Ashok BS, Lakshman K, Jayaveera KN, Ranganayakulu D, Manoj B. Comparative in vitro anthelmintic activity of three plants belongs to Amaranthaceae. Arch Biol Sci. 2010;62(1):185-189.
7. Kumar Ashok BS, Lakshman K, Jayaveera KN, Sheshadri Sekar D, Velmurugan C. Antinociceptive and Antipyretic activities of methanolic extract of Amaranthus caudatus Linn. Latin American J Pharm. 2010;29(4):1-5.
8. Plate AY, Areas JA. Cholesterol lowering effect of extruded amaranth (Amaranthus caudatus Lin.) in hypercholesterolemic rabbits. Food Chem 2002;76:1-6.
9. Conforti F, Statti G, Loizzo MR, Sacchetti G, Poli F, Menichini F. In Vitro antioxidant effect and inhibition of α-amylase of two varieties of Amaranthus caudatus seeds. Biol Pharm Bull 2005 Jun;28(6):1098-1102.
10. Bruni R, Medici A, Guerrini A, Scalia S, Poli F, Muzzoli M, et al. Wild Amaranthus caudatus seed oil, a nutraceutical resource from Ecuadorian flora. J Agric Food Chem 2001 Nov;49(11):5455-5460.
11. Broekaert WF, Marien W, Terras FR, Debolle MF, Proost P, Vandamme J, et al. Antimicrobial peptides from Amaranthus caudatus seed with sequence homologue to the cystein/glycine-rich domain of chitin-binding proteins. Biochem. 1992;31:4308-4314.
12. Thomas R. Transue, Alexander K, Smith, Hanquing, Irwin J, Goldstein, Mark A, Saper. Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin. Nat Struct Mol Biol 1997;4:779-783.
13. Rastrelli L, Aquino R. Abdos, Proto M, Desimone F, De Tommasin. Studies on the constituents of Amaranthus caudatus leaves; isolation and structure elucidation of new triterpenoid saponins and ionol-derived glycosides. J Agric Food Chem 1998;46(5):1797-1804.
14. Bruni R, Guerrini A, Scalia S, Romagnoli C, Sacchetti G. Rapid techniques for the extraction of vitamin E isomers from Amaranthus caudatus seeds: ultrasonic and supercritical fluid extraction. Phytochem Anal 2002 Sep-Oct;13(5):257-261.
15. Rinderle SJ, Goldstein IJ, Matta KL, Ratcliffe RM. Isolation and characterization of amaranthin, a lectin present in the seeds of Amaranthus caudatus, that recognizes the T-(or cryptic T)-antigen. J Biol Chem 1989 Sep;264(27):16123-16131.
16. st ed. Vallabh Prakashan, New Delhi, 1986; 111.
17. Slinkard K, Singleton VL. Total phenol analyses:automation and comparison with manual methods. Am J Enol Vitic 1977;28:49-55.
18. Gella FJ, Gubern G, Vidal R, Canalias F. Determination of total and pancreatic α-amylase in human serum with 2-chloro-4-nitrophenyl-α-D-maltotrioside as substrate. Clin Chim Acta 1997 Mar;259(1-2):147-160.
19. Vani T, Rajani M, Sarkar S, Shishoo CJ. Antioxidant properties of the ayurvedic formulation Triphala and its constituents. Int J Pharmacognosy 1997;35:313-317.
20. Sreejayan M, Rao MN. Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol 1997 Jan;49(1):105-107.
21. Yen GC, Chen HY. Antioxidant activity of various teas extracts in relation to their antimutagenicity. J Agric Food Chem 1995;43:27-32.
22. Auddy B, Ferreira M, Blasina F, Lafon L, Arredondo F, Dajas F, et al. Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases. J Ethnopharmacol 2003 Feb;84(2-3):131-138.
23. Kunchandy E, Rao MN. Oxygen radical scavenging activity of curcumin. Int J Pharm 1990;58:237-240.
24. Yadav SB, Tripathy V, Singh RK, Pandey HP. Antioxidant activity of Cuscuta reflexa stems. Indian J Pharm Sci 2000;6:477.
25. Halliwell B, Gutteridge JM. Free radicals in biology and medicine Oxford. Oxford University Press, 1998.
26. Yazdanparast R, Ardestani A. In vitro antioxidant and free radical scavenging activity of Cyperus rotundus. J Med Food 2007 Dec;10(4):667-674.
27. Yazdanparast R, Bahramikias S, Ardestani A. Nosturtium officinale reduces oxidative stress and enhances antioxidant capacity in hypercholesterolemic rats. Chem Bio. Interact 2008;172:176-184.
28. Packer L, Ong AS. Biological oxidants and antioxidants: molecular mechanisms and health effects Champaign, IL: AOCS Press; 1997.
29. Jovanovic SV, Simic MG. Antioxidants in nutrition. Ann N Y Acad Sci 2000;899:326-334.
30. Hatano T, Edamatsu R, Mori A, Fujita Y, Yasuhara E. Effects of tannins and related polyphenols on superoxide anion radical and on 1,1-diphenyl-2-picrylhydrazyl. Chem Pharm Bull (Tokyo) 1989;37:2016-2023.
31. Zheng W, Wang SY. Antioxidant activity and phenolic compounds in selected herbs. J Agric Food Chem 2001 Nov;49(11):5165-5170.
32. th spring meeting, Naunyn-Schmiedebergs Abstract No.R27 cited in Arch Pharmacol, 1979;307:R1-R77.
33. Zhu N, Wang M, We GJ, Lin JK, Yang CS, Ho CT. Identification of reaction products of (-) epigallocatechine, (-) epigallocatechin gallate and pyrogallol with DPPB. Food Chem 2001;73:345-349.
34. Korycks-Dahl M, Richardson T. Photogeneration of superoxide anion in serum of bovine milk and in model systems containing riboflavin and amino acids. J Dairy Sci 1977;60:363-369.
35. Robak J, Gryglewski RJ. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 1988 Mar;37(5):837-841.
36. Taylor BS, Kim YM, Wang QI, Shapiro RA, Billiar TR, Geller DA. Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression. Arch Surg 1997 Nov;132(11):1177-1183.
37. Huie RE, Padmaja S. The reaction of no with superoxide. Free Radic Res Commun 1993;18(4):195-199.
38. Mathew S, Abraham TE. In vitro antioxidant activity and scavenging effects of Cinnamomum verum leaf extract assayed by different methodologies. Food Chem Toxicol 2006 Feb;44(2):198-206.
39. International Expert Committee. International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 2009 Jul;32(7):1327-1334.