Synthesis by ring-closing metathesis and cytotoxic evaluation of Novel Thienylmacrolactones

Scientia Pharmaceutica

Volumn 80, Issue 1, 2012, Pages 29-36

  Krauss, Jürgen ^a   Köbler, Daniela ^a   Miller, Verena ^a   Bracher, Franz ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Grignard reaction; Macrolactones; MTT assay; Ring closing metathesis; Thiophenes

Indexed keywords

1 (THIOPHEN 2 YL)HEX 5 EN 1 OL; 1 (THIOPHEN 2 YL)HEX 5 EN 1 YL UNDEC 10 ENOATE; 11,12 DIHYDROXY 16 (THIOPHEN 2 YL)OXACYCLOHEXADECAN 2 ONE; 16 (THIOPHEN 2 YL)OXACYCLOHEXADEC 11 EN 2 ONE; ALDEHYDE DERIVATIVE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BENZYLIDENE(DICHLORO)BIS(TRICYCLOHEXYLPHOSPHANE)RUTHENIUM; BENZYLIDENE[1,3 BIS(2,4,6 TRIMETHYLPHENYL) 2 IMIDAZOLIDINYLIDENE]DICHLORO(TRICYCLOHEXYLPHOSPHANE)RUTHENIUM; CISPLATIN; CLOTRIMAZOLE; EPOTHILONE DERIVATIVE; LACTONE DERIVATIVE; METHANOL DERIVATIVE; RUTHENIUM DERIVATIVE; TETRACYCLINE; THIENYL CARBINOL; THIENYLMACROLACTONE DERIVATIVE; THIOPHENE 2 CARBALDEHYDE; UNCLASSIFIED DRUG;

AGAR DIFFUSION; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYST; CHEMICAL BOND; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; DIHYDROXYLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RING CLOSING METATHESIS;

EID: 84857945268     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.1109-09     Document Type: Article

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