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Volumn 62, Issue 23, 1997, Pages 8188-8192

Salicylihalamides A and B, novel cytotoxic macrolides from the marine sponge Haliclona sp.

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; MACROLIDE; SALICYLIHALAMIDE A; SALICYLIHALAMIDE B; UNCLASSIFIED DRUG;

EID: 0030711108     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971556g     Document Type: Article
Times cited : (256)

References (34)
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    • (g) Shen, Y.-C.; Tai, H.-R.; Duh, C.-Y. Chin. Pharm. J. (Taipei) 1996, 48, 1-10 (Chem. Abstr. 1996, 125, 82280).
    • (1996) Chem. Abstr. , vol.125 , pp. 82280
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    • 0000719887 scopus 로고
    • DeVita, V. T., Jr., Hellman, S., Rosenberg, S. A., Eds.; Lippincott: Philadelphia
    • (a) Boyd, M. R. In Cancer: Principles and Practice of Oncology Updates; DeVita, V. T., Jr., Hellman, S., Rosenberg, S. A., Eds.; Lippincott: Philadelphia, 1989; Vol. 3, No. 10; pp 1-12;
    • (1989) Cancer: Principles and Practice of Oncology Updates , vol.3 , Issue.10 , pp. 1-12
    • Boyd, M.R.1
  • 16
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    • note
    • 6 revealed the following correlations (H/H): 4/6, 5/6, 8a/8b, 8a/9, 8a/10, 8a/11b, 8b/9, 9/10, 10/ 11a, 10/11b, 11a/11b, 11a/12, 11b/12, 12/13, 12/26, 13/14a, 13/14b, 14a/ 14b, 14a/15, 14b/15, 15/16a, 15/16b, 16a/16b, 16a/17, 16a/18, 16b/17, 16b/18, 17/18, 18/NH, 20/21, 20/22, 20/23, 21/22, 21/23, 22/23, 22/24, 23/24, 24/25.
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    • For more recent applications see
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    • (1973) J. Am. Chem. Soc. , vol.95 , pp. 512-519
    • Dale, J.A.1    Mosher, H.S.2
  • 19
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    • and references therein
    • (c) Butler, W. M.; Koreeda, M. J. Org. Chem. 1989, 54, 4499-4503 and references therein.
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    • note
    • A small amount of the tris-MTPA derivative (diester imide) was formed in each case and removed by preparative TLC prior to NMR analyses (see Experimental Section).


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