Solubilization and anticancer-activity enhancement of Methotrexate by novel dendrimeric nanodevices synthesized in one-step reaction

Bioorganic Chemistry

Volumn 41-42, Issue , 2012, Pages 13-21

  Soto Castro, Delia ^a   Cruz Morales, Jorge A ^a   Apan, María Teresa Ramírez ^a   Guadarrama, Patricia ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Conjugates; Dendrimers; Encapsulation; Methotrexate; Nanodevices

Indexed keywords

FOLIC ACID; METHOTREXATE; POLYAMIDOAMINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL GROWTH; DRUG TARGETING; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIMIT OF QUANTITATION; NANODEVICE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SOLUBILIZATION; SYNTHESIS; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DENDRIMERS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LYMPHOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; METHOTREXATE; NANOSTRUCTURES; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84857917614     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2012.01.002     Document Type: Article

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