The inhibition of lipopolysaccharide-induced macrophage inflammation by 4 compounds in Hypericum perforatum extract is partially dependent on the activation of SOCS3

Phytochemistry

Volumn 76, Issue , 2012, Pages 106-116

  Huang, Nan ^a   Rizshsky, Ludmila ^a   Hauck, Catherine C ^a   Nikolau, Basil J ^a   Murphy, Patricia A ^a   Birt, Diane F ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Guttiferae; Hypericum perforatum; Inflammation; Lipopolysaccharide; Macrophage; Nitric oxide; Prostaglandin E2; St. John's wort; Suppressor of cytokine signaling 3

Indexed keywords

ALCOHOL; AMENTOFLAVONE; ANTIINFLAMMATORY AGENT; AUTACOID; BIFLAVONOID; CHLOROGENIC ACID; CYTOKINE; DRUG DERIVATIVE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PERYLENE; PROSTAGLANDIN E2; PSEUDOHYPERICIN; QUERCETIN; SMALL INTERFERING RNA; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HYPERICUM; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; MOUSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIFLAVONOIDS; CELL LINE; CHLOROGENIC ACID; CYTOKINES; DINOPROSTONE; ETHANOL; GENE KNOCKDOWN TECHNIQUES; HYPERICUM; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; PERYLENE; QUERCETIN; RNA, SMALL INTERFERING; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION, GENETIC; TRANSFECTION;

CLUSIACEAE; HYPERICUM PERFORATUM;

EID: 84857915404     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2011.12.001     Document Type: Article

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