One pot synthesis and anticancer activity of dimeric phloroglucinols

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 6, 2012, Pages 2251-2256

  Chauthe, Siddheshwar K ^a   Bharate, Sandip B ^a   Periyasamy, Giridharan ^b   Khanna, Amit ^b   Bhutani, Kamlesh K ^a   Mishra, Prabhu D ^b   Singh, Inder P ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b Piramal Enterprises Limited   (India)

Author keywords

2,4 Diacetyl phloroglucinol; Anticancer; Cytotoxic; Dimeric; Phloroglucinol

Indexed keywords

1 NAPTHYL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); 2,4 BIS (TRIFLOUROMETHYL) 1 BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); 2,4 BIS (TRIFLOUROMETHYL) 1 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); 3,4 METHYLENEDIOXY 1 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); 3,4 METHYLENEDIOXY 1 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); 4 BENZYLOXY 1 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); 4 BIPHENYL 1 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); 4 BIPHENYL 1 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); BENZOFURAN 2 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); BENZOFURAN 2 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); CYCLOHEXYL METHYL METHYLENE BIS (3,5 DI ISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); ETHYL METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); FLOURENE 2 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); FLUORENE 2 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); GEMCITABINE; IMIDAZOLE 2 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); IMIDAZOLE 2 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); METHYL METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); PHENYL METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); PHLOROGLUCINOL DERIVATIVE; PYRIDIN 2 YL METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); PYRIDINE 3 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); PYRIDINE 4 YL METHYLENE BIS (3 ISOPENTANOYL 5 FORMYL 2,4,6 TRIHYDROXYBENZENE); THIANAPTHENE 2 YL METHYLENE BIS (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); THIOPHENYL 2 YL METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXYBENZENE); UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; ONE POT SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DIMERIZATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MESYLATES; PHLOROGLUCINOL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84857915324     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.01.089     Document Type: Article

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