Biomimetic synthesis and anti-HIV activity of dimeric phloroglucinols

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 5, 2010, Pages 2029-2036

  Chauthe, Siddheshwar K ^a   Bharate, Sandip B ^a   Sabde, Sudeep ^b   Mitra, Debashis ^b   Bhutani, Kamlesh K ^a   Singh, Inder P ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Anti HIV activity; Antivirals; CEM GFP cells; Phloroglucinol

Indexed keywords

1 3 ACETYL 5 (3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYL) 2 PHENYLETHYLMETHYL 2,4,6 TRIHYDROXYPHENYLETHANONE; 1 3 ACETYL 5 (3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYLCYCLOHEXYLMETHYL) 2,4,6 TRIHYDROXYPHENYLETHANONE; 1 3 ACETYL 5 (3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYLETHYLMETHYL) 2,4,6-TRIHYDROXYPHENYLETHANONE; 1 3 ACETYL 5 [(3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYL) 4 HYDROXYPHENYLMETHYL] 2,4,6 TRIHYDROXYPHENYLETHANONE; 1 3 ACETYL 5 [(3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYL) QUINOLIN 4 YLMETHYL] 2,4,6 TRIHYDROXYPHENYLETHANONE; 1 [3 ACETYL 5 ((3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYL) 4 N,N DIMETHYLAMINOPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] ETHANONE; 1 [3 ACETYL 5 (3,5 DIACETYL 2,4,6 TRIHYDROXYPHENYLFURAN 2 YLMETHYL) 2,4,6 TRIHYDROXYPHENYL] ETHANONE; 1 [3 FORMYL 5 ((5 FORMYL 3 ISOPENTANOYL 2,4,6 TRIHYDROXYPHENYL) 4 BENZYLOXYPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 FORMYL 5 (5 FORMYL 3 ISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLPYRIDIN 2 YLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 ((3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYL) 3,4 METHYLENEDIOXYPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 ((3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYL) 4 BENZYLOXYPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 ((3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYL) 4 HYDROXYPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLFURAN 2 YLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLPHENYLETHYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLPHENYLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLPYRIDIN 2 YLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; 1 [3 ISOPENTANOYL 5 (3,5 DIISOPENTANOYL 2,4,6 TRIHYDROXYPHENYLQUINOLIN 4 YLMETHYL) 2,4,6 TRIHYDROXYPHENYL] 3 METHYLBUTAN 1 ONE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; METHYLENE BIS (3 FORMYL 5 ISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); METHYLENE BIS (3,5 DI ISOBUTANOYL 2,4,6 TRIHYDROXYBENZENE); METHYLENE BIS (3,5 DI ISOPENTANOYL 2,4,6 TRIHYDROXYBENZENE); METHYLENE BIS (3,5 DIACETYL 2,4,6 TRIHYDROXY BENZENE); NEVIRAPINE; PHLOROGLUCINOL; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IC 50; STRUCTURE ACTIVITY RELATION;

ANTI-HIV AGENTS; BIOMIMETIC MATERIALS; DIMERIZATION; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HUMANS; PHLOROGLUCINOL; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77549083227     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.01.023     Document Type: Article

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