Predictors of positive blood cultures in critically ill patients: A retrospective evaluation

Croatian Medical Journal

Volumn 53, Issue 1, 2012, Pages 30-39

  Previsdomini, Marco ^a   Gini, Massimiliano ^a   Cerutti, Bernard ^b   Dolina, Marisa ^c   Perren, Andreas ^a  

^a Ospedale Regionale Bellinzona e Valli   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c Cantonal Institute of Microbiology   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PROCALCITONIN;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BLOOD CULTURE; CRITICALLY ILL PATIENT; DESCRIPTIVE RESEARCH; DISEASE SEVERITY; FEMALE; FEVER; HORMONE BLOOD LEVEL; HOSPITAL PATIENT; HUMAN; LENGTH OF STAY; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; RETROSPECTIVE STUDY; SCORING SYSTEM; SEQUENTIAL ORGAN FAILURE ASSESSMENT; SIMPLIFIED ACUTE PHYSIOLOGY SCORE; SWITZERLAND; TREATMENT OUTCOME;

AGED; BACTEREMIA; CALCITONIN; CRITICAL ILLNESS; FEMALE; FEVER; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; LIVER FAILURE; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROTEIN PRECURSORS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 84857891347     PISSN: 03539504     EISSN: 13328166     Source Type: Journal    
DOI: 10.3325/cmj.2012.53.30     Document Type: Article

References (42)

1. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34:344-53.
2. Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, et al. Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA. 1995;274:968-74.
3. Grace CJ, Lieberman J, Pierce K, Littenberg B. Usefulness of blood culture for hospitalized patients who are receiving antibiotic therapy. Clin Infect Dis. 2001;32:1651-5.
4. Schermer CR, Sanchez DP, Qualls CR, Demarest GB, Albrecht RM, Fry DE. Blood culturing practices in a trauma intensive care unit: does concurrent antibiotic use make a difference? J Trauma. 2002;52:463-8.
5. McKenzie R, Reimer LG. Effect of antimicrobials on blood cultures in endocarditis. Diagn Microbiol Infect Dis. 1987;8:165-72.
6. Pazin GJ, Saul S, Thompson ME. Blood culture positivity: suppression by outpatient antibiotic therapy in patients with bacterial endocarditis. Arch Intern Med. 1982;142:263-8.
7. Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA. 1994;271:1598-601.
8. Leibovici L, Shraga I, Drucker M, Konigsberger H, Samra Z, Pitlik SD. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med. 1998;244:379-86.
9. Ibrahim EH, Sherman G, Ward S, Fraser VJ, Kollef MH. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest. 2000;118:146-55.
10. Schwenzer KJ, Gist A, Durbin CG. Can bacteremia be predicted in surgical intensive care unit patients? Intensive Care Med. 1994;20:425-30.
11. Bates DW, Goldman L, Lee TH. Contaminant blood cultures and resource utilization. The true consequences of false-positive results. JAMA. 1991;265:365-9.
12. Ortega M, Marco F, Soriano A, Almela M, Martínez JA, Munoz A, et al. Analysis of 4758 Escherichia coli bacteraemia episodes: predictive factors for isolation of an antibiotic-resistant strain and their impact on the outcome. J Antimicrob Chemother. 2009;63:568-74.
13. Zarrilli R, Crispino M, Bagattini M, Barretta E, Di Popolo A, Triassi M, et al. Molecular epidemiology of sequential outbreaks of Acinetobacter baumannii in an intensive care unit shows the emergence of carbapenem resistance. J Clin Microbiol. 2004;42:946-53.
14. Galicier C, Richet H. A prospective study of postoperative fever in a general surgery department. Infect Control. 1985;6:487-90.
15. Bell DM, Goldmann DA, Hopkins CC, Karchmer AW, Moellering RC Jr. Unreliability of fever and leukocytosis in the diagnosis of infection after cardiac valve surgery. J Thorac Cardiovasc Surg. 1978;75:87-90.
16. Torras-Comamala M, Aceituno-Ruiz R. Influence of axillary temperature on blood culture yield in the emergency department [in Spanish]. Enferm Clin. 2007;17:10-6.
17. Claridge JA, Golob JF Jr, Fadlalla AM, Malangoni MA, Blatnik J, Yowler CJ. Fever and leukocytosis in critically ill trauma patients: it is not the blood. Am Surg. 2009;75:405-10.
18. Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA. 1993;270:2957-63.
19. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22:707-10.
20. Shafazand S, Weinacker AB. Blood cultures in the critical care unit: improving utilization and yield. Chest. 2002;122:1727-36.
21. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20:864-74.
22. Tabriz MS, Riederer K, Baran J Jr, Khatib R. Repeating blood cultures during hospital stay: practice pattern at a teaching hospital and a proposal for guidelines. Clin Microbiol Infect. 2004;10:624-7.
23. Laupland KB, Davies HD, Church DL, Louie TJ, Dool JS, Zygun DA, et al. Bloodstream infection-associated sepsis and septic shock in critically ill adults: a population-based study. Infection. 2004;32:59-64.
24. Edgeworth JD, Treacher DF, Eykyn SJ. A 25-year study of nosocomial bacteremia in an adult intensive care unit. Crit Care Med. 1999;27:1421-8.
25. Smith-Elekes S, Weinstein MP. Blood cultures. Infect Dis Clin North Am. 1993;7:221-34.
26. Nakamura A, Wada H, Ikejiri M, Hatada T, Sakurai H, Matsushima Y, et al. Efficacy of procalcitonin in the early diagnosis of bacterial infections in a critical care unit. Shock. 2009;31:586-91.
27. Muller F, Christ-Crain M, Bregenzer T, Krause M, Zimmerli W, Mueller B, et al. Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial. Chest. 2010;138:121-9.
28. Koivula I, Hamalainen S, Jantunen E, Pulkki K, Kuittinen T, Nousiainen T, et al. Elevated procalcitonin predicts Gram-negative sepsis in haematological patients with febrile neutropenia. Scand J Infect Dis. 2011;43:471-8.
29. Graudal N, Milman N, Kirkegaard E, Korner B, Thomsen AC. Bacteremia in cirrhosis of the liver. Liver. 1986;6:297-301.
30. Graudal N, Hubeck B, Bonde J, Thomsen AC. The prognostic significance of bacteremia in hepatic cirrhosis. Liver. 1987;7:138-41.
31. Rolando N, Harvey F, Brahm J, Philpott-Howard J, Alexander G, Gimson A, et al. Prospective study of bacterial infection in acute liver failure: an analysis of fifty patients. Hepatology. 1990;11:49-53.
32. Metersky ML, Ma A, Bratzler DW, Houck PM. Predicting bacteremia in patients with community-acquired pneumonia. Am J Respir Crit Care Med. 2004;169:342-7.
33. Arii S, Imamura M. Physiological role of sinusoidal endothelial cells and Kupffer cells and their implication in the pathogenesis of liver injury. J Hepatobiliary Pancreat Surg. 2000;7:40-8.
34. Unsworth DJ. Complement deficiency and disease. J Clin Pathol. 2008;61:1013-7.
35. Stoeckle M, Kaech C, Trampus A, Zimmerli W. The role of diabetes mellitus in patients with blodstream infections. Swiss Med Wkly. 2008;138:512-9.
36. Garibaldi RA, Brodine S, Matsumiya S, Coleman M. Evidence for the non-infectious etiology of early postoperative fever. Infect Control. 1985;6:273-7.
37. Luna CM, Videla A, Mattera J, Vay C, Famiglietti A, Vujacich P, et al. Blood cultures have limited value in predicting severity of illness and as a diagnostic tool in ventilator-associated pneumonia. Chest. 1999;116:1075-84.
38. Gross PA, Van Antwerpen CL, Hess WA, Reilly KA. Use and abuse of blood cultures: program to limit use. Am J Infect Control. 1988;16:114-7.
39. Raymond DP, Pelletier SJ, Crabtree TD, Gleason TG, Pruett TL, Sawyer RG. Impact of bloodstream infection on outcomes among infected surgical inpatients. Ann Surg. 2001;233:549-55.
40. Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest. 1999;115:462-74.
41. Digiovine B, Chenoweth C, Watts C, Higgins M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med. 1999;160:976-81.
42. Cockerill FR III, Wilson JW, Vetter EA, Goodman KM, Torgerson CA, Harmsen WS, et al. Optimal testing parameters for blood cultures. Clin Infect Dis. 2004;38:1724-30.