Human neurocysticercosis: In vivo expansion of peripheral regulatory T cells and their recruitment in the central nervous system

Journal of Parasitology

Volumn 98, Issue 1, 2012, Pages 142-148

  Adalid Peralta, Laura ^a   Fleury, Agnes ^a   García Ibarra, Teresa M ^a,b   Hernández, Marisela ^a,b   Parkhouse, Michael ^a,c   Crispín, José Carlos ^a,d   Voltaire Proaño, Jefferson ^a,e   Cárdenas, Graciela ^a,b   Fragoso, Gladis ^a,b   Sciutto, Edda ^a,b  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HOSPITAL DE ESPECIALIDADES   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; CD69 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 6; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANNELID; CELL ORGANELLE; DISEASE PREVALENCE; FREQUENCY ANALYSIS; LARVA; NERVOUS SYSTEM; NEUROLOGY; PHYSIOLOGICAL RESPONSE;

ADULT; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MALE; NEUROCYSTICERCOSIS; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TAENIA SOLIUM;

ADRENAL CORTEX HORMONES; ADULT; ANIMALS; CD4-CD8 RATIO; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CYSTICERCUS; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MALE; NEUROCYSTICERCOSIS; T-LYMPHOCYTES, REGULATORY; TAENIA SOLIUM; VASOACTIVE INTESTINAL PEPTIDE;

TAENIA SOLIUM;

EID: 84857831130     PISSN: 00223395     EISSN: 19372345     Source Type: Journal    
DOI: 10.1645/GE-2839.1     Document Type: Article

References (38)

1. BELKAID, Y., AND K. TARBELL. 2009. Regulatory T cells in the control of host-microorganism interactions. Annual Review of Immunology 27: 551-589.
2. BETTELLI, E., Y. CARRIER, W. GAO, T. KORN, T. B. STROM, M. OUKKA, H. L. WEINER, AND V. K. KUCHROO. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
3. BULUT, D., M. SCHEELER, T. WICHMANN, J. BÖRGEL, T. MIEBACH, AND A. MÜGGE. 2010. Effect of protein A immunoadsorption on T cell activation in patients with inflammatory dilated cardiomyopathy. Clinical Research in Cardiology 99: 633-638.
4. CAO, X. 2010. Regulatory T cells and immune tolerance to tumors. Immunologic Research 46: 79-93.
5. CHAVARRÍA, A., A. FLEURY, R. J. BOBES, J. MORALES, G. FRAGOSO, AND E. SCIUTTO. 2006. A depressed peripheral cellular immune response is related to symptomatic neurocysticercosis. Microbes and Infection 8: 1082-1089.
6. -, -, E. GARCÍA, C. MÁRQUEZ, G. FRAGOSO, AND E. SCIUTTO. 2005. Relationship between the clinical heterogeneity of neurocysticercosis and the immune-inflammatory profiles. Clinical Immunology 116: 271-278.
7. COSTANTINO, C. M., C. M. BAECHER-ALLAN, AND D. A. HAFLER. 2008. Human regulatory T cells and autoimmunity. European Journal Immunology 38: 921-924.
8. CROKER, C., R. REPORTER, AND L. MASCOLA. 2010. Use of statewide hospital discharge data to evaluate the economic burden of neurocysticercosis in Los Angeles County (1991-2008). The American Journal of Tropical Medicine and Hygiene 83: 106-110.
9. DEL BRUTTO, O. H., E. GARCÍA, O, TALÁMAS, AND J. SOTELO. 1988. Sexrelated severity of inflammation in parenchymal brain cysticercosis. Archives of Internal Medicine 148: 544-546.
10. DELGADO, M., N. VARELA, AND E. GONZALEZ-REY. 2008. Vasoactive intestinal peptide protects against beta-amyloid-induced neurodegeneration by inhibiting microglia activation at multiple levels. Glia 56: 1091-1103.
11. D'ELIA, R., J. M. BEHNKE, J. E. BRADLEY, AND K. J. ELSE. 2009. Regulatory T cells: A role in the control of helminth-driven intestinal pathology and worm survival. Journal of Immunology 182: 2340-2348.
12. DIXON, H. B. F., AND F. M. LIPSCOMB. 1961. Cysticercosis: An analysis and follow-up of 450 cases. Medical Research Council Special Report Series No. 299, Her Majesty's Stationary Office, London, U.K., 58 p.
13. ERMANN, J., AND C. G. FATHMAN. 2003. Costimulatory signals controlling regulatory T cells. Proceedings of the National Academy of Sciences USA 100: 15292-15293.
14. FLEURY, A., A. DESSEIN, P. M. PREUX, M.DUMAS, G. TAPIA, C. LARRALDE, AND E. SCIUTTO. 2004. Symptomatic human neurocysticercosis-Age, sex and exposure factors relating with disease heterogeneity. Journal of Neurology 251: 830-837.
15. -, M. HERNÁNDEZ, M. AVILA, G. CÁRDENAS, R. J. BOBES, M. HUERTA, G. FRAGOSO, L. URIBE-CAMPERO, L. J. HARRISON, R. M. PARKHOUSE, and E. SCIUTTO. 2007. Detection of HP10 antigen in serum for diagnosis and follow-up of subarachnoidal and intraventricular human neurocysticercosis. The Journal of Neurology, Neurosurgery and Psychiatry 78: 970-974.
16. GANEA, D., E. GONZALEZ-REY, AND M. DELGADO. 2006. A novel mechanism for immunosuppression: From neuropeptides to regulatory T cells. Journal of Neuroimmune Pharmacology 1: 400-409.
17. GARCÍA, H. H., C. EVANS, T. NASH, O. M. TAKAYANAGUI, A. C. WHITE, JR., AND D. BOTERO. 2002. Current consensus guidelines for treatment of neurocysticercosis. Clinical Microbiological Review 15: 747-756.
18. -, A. E. GONZALEZ, C. A. EVANS, R. H. GILMAN, AND CYSTICERCOSIS WORKING GROUP IN PERU. 2003. Taenia solium cysticercosis. Lancet 362: 547-556.
19. GONZALEZ-REY, E., P. ANDERSON, AND M. DELGADO. 2007. Emerging roles of vasoactive intestinal peptide: A new approach for autoimmune therapy. Annals of the Rheumatic Diseases 66: 11170-11176.
20. GRIFFITHS, M., J. W. NEAL, AND P. GASQUE. 2007. Innate immunity and protective neuroinflammation: New emphasis on the role of neuroimmune regulatory proteins. International Review of Neurobiology 82: 29-55.
21. HAAS, J., L. SCHOPP, B. STORCH-HAGENLOCHER, B. FRITZSCHING, C. JACOBI, L. MILKOVA, B. FRITZ, A. SCHWARZ, E. SURI-PAYER, M. HENSEL, AND B. WILDEMANN. 2008. Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood 11: 761-766.
22. INFANTE-DUARTE, C., S. WAICZIES, J. WUERFEL, AND F. ZIPP. 2008. New developments in understanding and treating neuroinflammation. Journal of Molecular Medicine 86: 975-985.
23. JUNG, H., G. CÁRDENAS, E. SCIUTTO, AND A. FLEURY. 2008. Medical treatment for neurocysticercosis: Drugs, indications and perspectives. Current Topics in Medicinal Chemistry 8: 424-433.
24. KELLUM, J. A., I. KONG, M. P. FINK, L. A.WEISSFELD, D.M. YEALY, M. R. PINSKY, J. FINE, A. KRICHEVSKY, R. L. DELUDE, D. C. ANGUS, AND GENIMS INVESTIGATORS. 2007. Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the genetic and inflammatory markers of sepsis (GenIMS) study. Archives of Internal Medicine 167: 1655-1663.
25. + regulatory T cells in mice infected with the filarial parasite Brugia malayi. Journal of Immunology 181: 6456-6466.
26. OKANO, M. 2009. Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis. Clinical and Experimental Immunology 158: 164-173.
27. RADSTAKE, T. R., L. VAN BON, J. BROEN, M. WENINK, K. SANTEGOETS, Y. DENG, A. HUSSAINI, R. SIMMS, W. W. CRUIKSHANK, AND R. LAFYATIS. 2009. Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression. PLoS One 22: e5981.
28. SÁENZ, B., J. RAMÍREZ, A. ALUJA, A. ESCOBAR, G. FRAGOSO, J. MORALES, R. PÉREZ-TAMAYO, F. ROSETTI, C. LARRALDE, E. SCIUTTO, AND A. FLEURY. 2008. Human and porcine neurocysticercosis: Differences in the distribution and developmental stages of cysticerci. Tropical Medicine & International Health 13: 697-702.
29. SCIUTTO, E., G. FRAGOSO, A. FLEURY, J. P. LACLETTE, J. SOTELO, A. ALUJA, L. VARGAS, AND C. LARRALDE. 2000. Taenia solium disease in humans and pigs: An ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions. Microbes and Infection 2: 1875-1890.
30. SERPA, J., L. YANCEY, AND A. WHITE, JR. 2006. Advances in the diagnosis and management of neurocysticercosis. Expert Review of Antiinfective Therapy 4: 1051-1061.
31. SGAMBATO, A., AND A. CITTADINI. 2010. Inflammation and cancer: A multifaceted link. European Review for Medical and Pharmacological Sciences 14: 263-268.
32. SORVILLO, F., P. WILKINS, S. SHAFIR, AND M. EBERHARD. 2011. Public health implications of cysticercosis acquired in the United States. Emerging Infectious Diseases 17: 1-6.
33. SOTELO, J., AND O. H. DEL BRUTTO. 2002. Review of neurocysticercosis. Neurosurgical Focus 12: e1.
34. VAN DER KLEIJ, D., E. LATZ, J. F. BROUWERS, Y.C. KRUIZE, M. SCHMITZ, E. A. KURT-JONES, T. ESPEVIK, E. C. DE JONG, M. L. KAPSENBERG, D. T. GOLENBOCK, ET AL. 2002. A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization. The Journal of Biological Chemistry 48: 48122-48129.
35. WANG, J.,A. IOAN-FACSINAY, E. I.VAN DER VOORT, T.W. HUIZINGA, AND R. E. TOES. 2007. Transient expression of FoxP3 in human activated nonregulatory CD4+ T cells. European Journal of Immunology 37: 129-138.
36. ZACCONE, P.,O. T. BURTON, AND A. COOKE. 2008. Interplay of parasite-driven immune responses and autoimmunity. Trends in Parasitology 24: 35-42.
37. ZHANG, L., AND Y. ZHAO. 2007. The regulation of FoxP3 expression in regulatory CD4(+)CD25(+)T cells: Multiple pathways on the road. Journal of Cellular Physiology 211: 590-597.
38. ZIPP, F., AND O. AKTAS. 2006. The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases. Trends in Neurosciences 29: 518-527.