Stearoyl-Coa desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Matsui, Hiroki ^a,b   Yokoyama, Tomoyuki ^b   Sekiguchi, Kenichi ^a   Iijima, Daisuke ^b   Sunaga, Hiroaki ^b   Maniwa, Moeno ^b   Ueno, Manabu ^a   Iso, Tatsuya ^a   Arai, Masashi ^a   Kurabayashi, Masahiko ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; CASPASE 3; CERAMIDE; DIACYLGLYCEROL; GLUCOSE; INSULIN; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; SATURATED FATTY ACID; SMALL INTERFERING RNA; SUCROSE; ACYL COENZYME A DESATURASE; FATTY ACID; HYDROGEN PEROXIDE; MESSENGER RNA; OXIDIZING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; FATTY ACID OXIDATION; GLUCOSE OXIDATION; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; LIPID STORAGE; MALE; NEWBORN; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; ABDOMINAL OBESITY; ANIMAL; CELL CULTURE; DIET; DRUG EFFECT; GENE EXPRESSION; GENETICS; GLUCOSE BLOOD LEVEL; HEART MUSCLE; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION; WISTAR RAT;

MUS; RATTUS;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELLS, CULTURED; DIET; FATTY ACIDS; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION; HUMANS; HYDROGEN PEROXIDE; INSULIN; LIPID METABOLISM; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; OBESITY, ABDOMINAL; OXIDANTS; OXIDATION-REDUCTION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; STEAROYL-COA DESATURASE;

EID: 84857819523     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033283     Document Type: Article

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