-
1
-
-
0036741098
-
A role for local inflammation in the formation of drusen in the aging eye
-
Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134(3):411-431.
-
(2002)
Am J Ophthalmol
, vol.134
, Issue.3
, pp. 411-431
-
-
Anderson, D.H.1
Mullins, R.F.2
Hageman, G.S.3
Johnson, L.V.4
-
2
-
-
79954453398
-
Age-related macular degeneration: Genetic and clinical findings
-
Kokotas H, Grigoriadou M, Petersen MB. Age-related macular degeneration: genetic and clinical findings. Clin Chem Lab Med. 2010;49(4):601-616.
-
(2010)
Clin Chem Lab Med
, vol.49
, Issue.4
, pp. 601-616
-
-
Kokotas, H.1
Grigoriadou, M.2
Petersen, M.B.3
-
3
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
Edwards AO, Ritter R, Abel KJ, et al. Complement factor H polymorphism and age-related macular degeneration. Science. 2005; 308(5720):421-424.
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 421-424
-
-
Edwards, A.O.1
Ritter, R.2
Abel, K.J.3
-
4
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold B, Merriam JE, Zernant J, et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet. 2006;38(4):458-462.
-
(2006)
Nat Genet
, vol.38
, Issue.4
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
-
5
-
-
21044453724
-
A common haplo-type in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman GS, Anderson DH, Johnson LV, et al. A common haplo-type in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;102(20):7227-7232.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.20
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
-
6
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines JL, Hauser MA, Schmidt S, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308(5720):419-421.
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
-
7
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science. 2005; 308(5720):385-389.
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
-
8
-
-
27744462212
-
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
-
Rivera A, Fisher SA, Fritsche LG, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005;14(21):3227-3236.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.21
, pp. 3227-3236
-
-
Rivera, A.1
Fisher, S.A.2
Fritsche, L.G.3
-
9
-
-
44849088405
-
C3 R102G polymorphism increases risk of age-related macular degeneration
-
Spencer KL, Olson LM, Anderson BM, et al. C3 R102G polymorphism increases risk of age-related macular degeneration. Hum Mol Genet. 2008;17(12):1821-1824.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.12
, pp. 1821-1824
-
-
Spencer, K.L.1
Olson, L.M.2
Anderson, B.M.3
-
10
-
-
34547764305
-
Complement C3 variant and the risk of age-related macular degeneration
-
Yates JRW, Sepp T, Matharu BK, et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med. 2007; 357(6):553-561.
-
(2007)
N Engl J Med
, vol.357
, Issue.6
, pp. 553-561
-
-
Yates, J.R.W.1
Sepp, T.2
Matharu, B.K.3
-
11
-
-
46249098503
-
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
-
Fritsche LG, Loenhardt T, Janssen A, et al. Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet. 2008;40(7):892-896.
-
(2008)
Nat Genet
, vol.40
, Issue.7
, pp. 892-896
-
-
Fritsche, L.G.1
Loenhardt, T.2
Janssen, A.3
-
12
-
-
57649215855
-
Variation near complement factor I is associated with risk of advanced AMD
-
Fagerness JA, Maller JB, Neale BM, et al. Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet. 2008;17(1):100-104.
-
(2008)
Eur J Hum Genet
, vol.17
, Issue.1
, pp. 100-104
-
-
Fagerness, J.A.1
Maller, J.B.2
Neale, B.M.3
-
13
-
-
33749123246
-
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
-
Hughes AE, Orr N, Esfandiary H, et al. A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration. Nat Genet. 2006;38(10): 1173-1177.
-
(2006)
Nat Genet
, vol.38
, Issue.10
, pp. 1173-1177
-
-
Hughes, A.E.1
Orr, N.2
Esfandiary, H.3
-
14
-
-
33748325757
-
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
-
Li M, Atmaca-Sonmez P, Othman M, et al. CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet. 2006;38(9): 1049-1054.
-
(2006)
Nat Genet
, vol.38
, Issue.9
, pp. 1049-1054
-
-
Li, M.1
Atmaca-Sonmez, P.2
Othman, M.3
-
15
-
-
33748309136
-
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
-
Maller J, George S, Purcell S, et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet. 2006;38(9): 1055-1059.
-
(2006)
Nat Genet
, vol.38
, Issue.9
, pp. 1055-1059
-
-
Maller, J.1
George, S.2
Purcell, S.3
-
16
-
-
69449090499
-
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
-
Tortajada A, Montes T, Martínez-Barricarte R, et al. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Hum Mol Genet. 2009;18(18):3452-3461.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.18
, pp. 3452-3461
-
-
Tortajada, A.1
Montes, T.2
Martínez-Barricarte, R.3
-
17
-
-
63449141168
-
Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B
-
Montes T, Tortajada A, Morgan BP, Rodríguez de Co ́rdoba S, Harris CL. Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B. Proc Natl Acad Sci USA. 2009;106(11):4366-4371.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.11
, pp. 4366-4371
-
-
Montes, T.1
Tortajada, A.2
Morgan, B.P.3
de Rodríguez Córdoba, S.4
Harris, C.L.5
-
18
-
-
79957691055
-
Common polymorphisms in C3, factor B and factor H collaborate to determine systemic complement activity and disease risk
-
Heurich M, Martínez-Barricarte R, Francis NJ, et al. Common polymorphisms in C3, factor B and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci USA. 2010;108:8761-8766.
-
(2010)
Proc Natl Acad Sci USA
, vol.108
, pp. 8761-8766
-
-
Heurich, M.1
Martínez-Barricarte, R.2
Francis, N.J.3
-
19
-
-
33747700932
-
His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form
-
Clark SJ, Higman VA, Mulloy B, et al. His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form. J Biol Chem. 2006;281(34):24713-24720.
-
(2006)
J Biol Chem
, vol.281
, Issue.34
, pp. 24713-24720
-
-
Clark, S.J.1
Higman, V.A.2
Mulloy, B.3
-
20
-
-
34948910047
-
Structural basis for complement factor H-linked age-related macular degeneration
-
Prosser BE, Johnson S, Roversi P, et al. Structural basis for complement factor H-linked age-related macular degeneration. J Exp Med. 2007;204(10):2277-2283.
-
(2007)
J Exp Med
, vol.204
, Issue.10
, pp. 2277-2283
-
-
Prosser, B.E.1
Johnson, S.2
Roversi, P.3
-
21
-
-
34247573496
-
Defective complement control of Factor H (Y402H) and FHL-1 in age-related macular degeneration
-
Skerka C, Lauer N, Weinberger AAWA, et al. Defective complement control of Factor H (Y402H) and FHL-1 in age-related macular degeneration. Mol Immunol. 2007;44(13):3398-3406.
-
(2007)
Mol Immunol
, vol.44
, Issue.13
, pp. 3398-3406
-
-
Skerka, C.1
Lauer, N.2
Weinberger, A.A.W.A.3
-
22
-
-
77956897697
-
Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina
-
Clark SJ, Perveen R, Hakobyan S, et al. Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. J Biol Chem. 2010;285(39):30192-30202.
-
(2010)
J Biol Chem
, vol.285
, Issue.39
, pp. 30192-30202
-
-
Clark, S.J.1
Perveen, R.2
Hakobyan, S.3
-
23
-
-
36849084660
-
Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H
-
de Rodríguez Córdoba S, Goicoechea de Jorge E. Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H. Clin Exp Immunol. 2008;151(1):1-13.
-
(2008)
Clin Exp Immunol
, vol.151
, Issue.1
, pp. 1-13
-
-
de Rodríguez Córdoba, S.1
Goicoechea de Jorge, E.2
-
24
-
-
33847153137
-
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications
-
Hageman G, Hancox L, Taiber A, et al. Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. Ann Med. 2006;38(8):592-604.
-
(2006)
Ann Med
, vol.38
, Issue.8
, pp. 592-604
-
-
Hageman, G.1
Hancox, L.2
Taiber, A.3
-
25
-
-
34250329129
-
Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
-
Pickering MC, de Jorge EG, Martinez-Barricarte R, et al. Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains. J Exp Med. 2007;204(6): 1249-1256.
-
(2007)
J Exp Med
, vol.204
, Issue.6
, pp. 1249-1256
-
-
Pickering, M.C.1
de Jorge, E.G.2
Martinez-Barricarte, R.3
-
26
-
-
70349437186
-
Complement regulators and inhibitory proteins
-
Zipfel PF, Skerka C. Complement regulators and inhibitory proteins. Nat Rev Immunol. 2009;9(10):729-740.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.10
, pp. 729-740
-
-
Zipfel, P.F.1
Skerka, C.2
-
27
-
-
78149270873
-
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
-
Fritsche LG, Lauer N, Hartmann A, et al. An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD). Hum Mol Genet. 2010;19(23):4694-4704.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.23
, pp. 4694-4704
-
-
Fritsche, L.G.1
Lauer, N.2
Hartmann, A.3
-
28
-
-
0033652453
-
Risk factors associated with age-related macular degeneration: A case-control study in the age-related eye disease study: Age-related eye disease study report number 3
-
Age-Related Eye Disease Study Research Group
-
Age-Related Eye Disease Study Research Group. Risk factors associated with age-related macular degeneration: a case-control study in the age-related eye disease study: age-related eye disease study report number 3. Ophthalmology. 2000;107(12):2224-2232.
-
(2000)
Ophthalmology
, vol.107
, Issue.12
, pp. 2224-2232
-
-
-
29
-
-
76949087440
-
Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemo-lytic uremic syndrome
-
Abarrategui-Garrido C, Martinez-Barricarte R, Lopez-Trascasa M, Rodriguez de Cordoba S, Sanchez-Corral P. Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemo-lytic uremic syndrome. Blood. 2009;114(19):4261-4271.
-
(2009)
Blood
, vol.114
, Issue.19
, pp. 4261-4271
-
-
Abarrategui-Garrido, C.1
Martinez-Barricarte, R.2
Lopez-Trascasa, M.3
Rodriguez de Cordoba, S.4
Sanchez-Corral, P.5
-
30
-
-
33745085461
-
MIDAS: Software for analysis and visualisation of interallelic disequilibrium between multiallelic markers
-
Gaunt T, Rodriguez S, Zapata C, Day I. MIDAS: software for analysis and visualisation of interallelic disequilibrium between multiallelic markers. BMC Bioinformatics. 2006;7(1):227.
-
(2006)
BMC Bioinformatics
, vol.7
, Issue.1
, pp. 227
-
-
Gaunt, T.1
Rodriguez, S.2
Zapata, C.3
Day, I.4
-
31
-
-
79959348804
-
Prevalence of age-related macular degeneration in Spain
-
Spanish Eyes Epidemiological Study Group
-
Spanish Eyes Epidemiological Study Group. Prevalence of age-related macular degeneration in Spain. Br J Ophthalmol. 2011; 95(7):931-936.
-
(2011)
Br J Ophthalmol
, vol.95
, Issue.7
, pp. 931-936
-
-
|