Comparison of cellular damage response to low-dose-rate 125I seed irradiation and high-dose-rate gamma irradiation in human lung cancer cells

Brachytherapy

Volumn 11, Issue 2, 2012, Pages 149-156

  Chen, Honghong ^a   Bao, Yizhong ^a   Yu, Lei ^a   Jia, Rongfei ^a   Cheng, Wenying ^a   Shao, Chunlin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

HDR irradiation; Ku protein; LDR 125I seeds; Lung cancer cells; Radiosensitivity

Indexed keywords

IODINE 125; WORTMANNIN;

ARTICLE; CANCER CELL; CELL DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; GAMMA IRRADIATION; HIGH DOSE RATE GAMMA IRRADIATION; HUMAN; HUMAN CELL; IRRADIATION; LOW DOSE RATE SEED IRRADIATION; MICRONUCLEUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIOSENSITIVITY;

CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HUMANS; IODINE RADIOISOTOPES; LUNG NEOPLASMS; MICRONUCLEUS TESTS;

EID: 84857800534     PISSN: 15384721     EISSN: 18731449     Source Type: Journal    
DOI: 10.1016/j.brachy.2011.05.002     Document Type: Article

References (27)

1. Heysek R.V. Modern brachytherapy for treatment of prostate cancer. Cancer Control 2007, 14:238-243.
2. Chen A.M., Chang S., Pouliot J., et al. Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2007, 69:825-830.
3. Vavrova J., Rezacova M., Vokurkova D., et al. Cell cycle alteration, apoptosis and response of leukemic cell lines to gamma radiation with high- and low-dose rate. Physiol Res 2004, 53:335-342.
4. Collis S.J., Swartz M.J., Nelson W.G., et al. Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. Cancer Res 2003, 63:1550-1554.
5. Pisch J., Belsley S.J., Ashton R., et al. Placement of 125I implants with the da Vinci robotic system after video-assisted thoracoscopic wedge resection: A feasibility study. Int J Radiat Oncol Biol Phys 2004, 60:928-932.
6. Martinez-Monge R., Pagola M., Vivas I., et al. CT-guided permanent brachytherapy for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC). Lung Cancer 2008, 61:209-213.
7. Branzei D., Foiani M. Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 2008, 9:297-308.
8. Mahaney B.L., Meek K., Lees-Miller S.P. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 2009, 417:639-650.
9. Wilson C.R., Davidson S.E., Margison G.P., et al. Expression of Ku70 correlates with survival in carcinoma of the cervix. Br J Cancer 2000, 83:1702-1706.
10. Komuro Y., Watanabe T., Hosoi Y., et al. The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma. Cancer 2002, 95:1199-1205.
11. Nimura Y., Kawata T., Uzawa K., et al. Silencing Ku80 using small interfering RNA enhanced radiation sensitivity in vitro and in vivo. Int J Oncol 2007, 30:1477-1484.
12. Yang Q.S., Gu J.L., Du L.Q., et al. ShRNA-mediated Ku80 gene silencing inhibits cell proliferation and sensitizes to gamma-radiation and mitomycin C-induced apoptosis in esophageal squamous cell carcinoma lines. J Radiat Res (Tokyo) 2008, 49:399-407.
13. He F., Li L., Kim D., et al. Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions. Cancer Res 2007, 67:634-642.
14. Ayene I.S., Ford L.P., Koch C.J. Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. Mol Cancer Ther 2005, 4:529-536.
15. Ortiz T., Lopez S., Burguillos M.A., et al. Radiosensitizer effect of wortmannin in radioresistant bladder tumoral cell lines. Int J Oncol 2004, 24:169-175.
16. Okayasu R., Suetomi K., Yu Y., et al. A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse. Cancer Res 2000, 60:4342-4345.
17. Sakata K., Matsumoto Y., Satoh M., et al. Clinical studies of immunohistochemical staining of DNA-dependent protein kinase in oropharyngeal and hypopharyngeal carcinomas. Radiat Med 2001, 19:93-97.
18. Kodym E., Kodym R., Chen B.P., et al. DNA-PKcs-dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 inhibitor. Int J Radiat Oncol Biol Phys 2007, 69:187-193.
19. Tomita M., Morohoshi F., Matsumoto Y., et al. Role of DNA double-strand break repair genes in cell proliferation under low dose-rate irradiation conditions. J Radiat Res (Tokyo) 2008, 49:557-564.
20. Chen H.H., Jia R.F., Yu L., et al. Bystander effects induced by continuous low-dose-rate 125I seeds potentiate the killing action of irradiation on human lung cancer cells in vitro. Int J Radiat Oncol Biol Phys 2008, 72:1560-1566.
21. Nath R. Dosimetry of Interstitial Brachytherapy Sources:Recommendations of the AAPM Radiation Therapy Committee Task Group No. 43. Med Phys 1995, 22:209-234.
22. Sarkaria J.N., Bush C., Eady J.J., et al. Comparison between pulsed-field gel electrophoresis and the comet assay as predictive assays for radiosensitivity in fibroblasts. Radiat Res 1998, 150:17-22.
23. Negroni A., Stronati L., Grollino M.G., et al. Radioresistance in a tumour cell line correlates with radiation inducible Ku 70/80 end-binding activity. Int J Radiat Biol 2008, 84:265-276.
24. Owen D.G., McNamee J.P., Raaphorst G.P., et al. Potentiation of cell killing by low-dose-rate radiation by camptothecin is related to an increase in the level of DNA double-strand breaks. Radiat Res 2002, 157:149-157.
25. Guo W.F., Lin R.X., Huang J., et al. Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis. Radiat Res 2005, 164:27-35.
26. Dicker A.P., Lin C.C., Leeper D.B., et al. Isotope selection for permanent prostate implants? An evaluation of 103Pd versus 125I based on radiobiological effectiveness and dosimetry. Semin Urol Oncol 2000, 18:152-159.
27. Sak A., Stuschke M., Wurm R., et al. Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: Consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines. Cancer Res 2002, 62:6621-6624.